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The map label for this gene is add [H]

Identifier: 159899316

GI number: 159899316

Start: 3556150

End: 3557190

Strand: Direct

Name: add [H]

Synonym: Haur_2797

Alternate gene names: 159899316

Gene position: 3556150-3557190 (Clockwise)

Preceding gene: 159899315

Following gene: 159899319

Centisome position: 56.03

GC content: 52.35

Gene sequence:

>1041_bases
ATGCACTCGCCGCTTGCTGAATTTATTCGCCGCATGCCCAAATGTGAGCTTCATGTTCACTTAGAAGGCTCGATTACCCC
TAAAACGCTTTTAGAGCTAGCGACGAAGAATGGCATTAGCTTGCCTGCTAGCGATTTGGCTGGGGTCGAGCGCATGTTTC
AATATGAACATTTCCTCGGCTTTTTGGATGTGTATCGCACCTGTGCTCGCTGTTTGATCCATGGTGAGGATTTTGAGCGG
GTTGCCTATGAATTGGCAATCGATTTGGCGCAACAACAGGTGCGTTATGCTGAAGTGATGCTCTCGCCTGCTCAGCACAT
GCTCCGCAACATGGATTTCGATGAGATTCTTGGTGGTGTTGCGGCTGGGTTTGCCCGTGCTGAGCGCGAGATGGGCATTG
TGTGTCGGCCTGCCTTTGATTTTGGTCGGCAGTTTAGCCTTGATCAAGCCTTACGAGCGGTCGAGTTGGCCCAAGCTGGC
ATGCAATATGGGGTTGTCGCCTTTTCGATTGGCGGCGATGAGGCCAACTATCCCCCTGAGCCGTTTGTTGAGGTGTTTGC
CTTGGCCAAGGCGGTTGGGCTGCACGTTATGGCTCATGCTGGCGAGGTCGCTGGGGCCAATAGCGTGCGCGGCGCAGTCG
AAATGCTGGGCGTAGATCGAATTGGCCATGGTTTTCGGGTGCTTGAGGATGCCGAATTAACCCAATTTCTGGCTCGCCGT
GGCGATATTACCTTCGATGTGTGCCCAACCAGCAATATTCGGACTGGTGTGGTTGCCTCGTTTGATCAACACCCTCTGCG
CCAGATGCTCGATGCTGGATTGCCAATTACCCTCAACTCCGATGATCCAGTCTTGTTTGATACAACAGTAACTGGTGAGT
TTTTGCTGGCCGCCGAACGCTATGATTTTACGATTGATGATATTTGTAAAGTCGCCCGCCAAAGCGCCAAAGCCGCCTTC
TTACCAGCCGAACAACGCCAACAACTGCTGCTTGAGTTTGATCAACAACAAGCCCAATTGCGGCGCGAACTCGGCTTATA
A

Upstream 100 bases:

>100_bases
TGCTTGATGGAGCGCTTGATCGCTTGATCGATGCGCTAGTTACCTTCGACAACGCCGAACGGCTTAAGGCCTTGGGTATG
GGAGCCTAGGAGTTTGTTGC

Downstream 100 bases:

>100_bases
TCCGAAGAGCATAGAACAGAACAGAGGGTTCATTCTCTGCCCTTCCAGCAGGCGAGAGGAAACTATGCCATGATAGCTAT
TAGAACTTCCAGCTATGGTC

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MHSPLAEFIRRMPKCELHVHLEGSITPKTLLELATKNGISLPASDLAGVERMFQYEHFLGFLDVYRTCARCLIHGEDFER
VAYELAIDLAQQQVRYAEVMLSPAQHMLRNMDFDEILGGVAAGFARAEREMGIVCRPAFDFGRQFSLDQALRAVELAQAG
MQYGVVAFSIGGDEANYPPEPFVEVFALAKAVGLHVMAHAGEVAGANSVRGAVEMLGVDRIGHGFRVLEDAELTQFLARR
GDITFDVCPTSNIRTGVVASFDQHPLRQMLDAGLPITLNSDDPVLFDTTVTGEFLLAAERYDFTIDDICKVARQSAKAAF
LPAEQRQQLLLEFDQQQAQLRRELGL

Sequences:

>Translated_346_residues
MHSPLAEFIRRMPKCELHVHLEGSITPKTLLELATKNGISLPASDLAGVERMFQYEHFLGFLDVYRTCARCLIHGEDFER
VAYELAIDLAQQQVRYAEVMLSPAQHMLRNMDFDEILGGVAAGFARAEREMGIVCRPAFDFGRQFSLDQALRAVELAQAG
MQYGVVAFSIGGDEANYPPEPFVEVFALAKAVGLHVMAHAGEVAGANSVRGAVEMLGVDRIGHGFRVLEDAELTQFLARR
GDITFDVCPTSNIRTGVVASFDQHPLRQMLDAGLPITLNSDDPVLFDTTVTGEFLLAAERYDFTIDDICKVARQSAKAAF
LPAEQRQQLLLEFDQQQAQLRRELGL
>Mature_346_residues
MHSPLAEFIRRMPKCELHVHLEGSITPKTLLELATKNGISLPASDLAGVERMFQYEHFLGFLDVYRTCARCLIHGEDFER
VAYELAIDLAQQQVRYAEVMLSPAQHMLRNMDFDEILGGVAAGFARAEREMGIVCRPAFDFGRQFSLDQALRAVELAQAG
MQYGVVAFSIGGDEANYPPEPFVEVFALAKAVGLHVMAHAGEVAGANSVRGAVEMLGVDRIGHGFRVLEDAELTQFLARR
GDITFDVCPTSNIRTGVVASFDQHPLRQMLDAGLPITLNSDDPVLFDTTVTGEFLLAAERYDFTIDDICKVARQSAKAAF
LPAEQRQQLLLEFDQQQAQLRRELGL

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=343, Percent_Identity=31.4868804664723, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI226693318, Length=337, Percent_Identity=22.5519287833828, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787910, Length=323, Percent_Identity=30.6501547987616, Blast_Score=147, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI32565969, Length=342, Percent_Identity=29.5321637426901, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17538512, Length=342, Percent_Identity=29.5321637426901, Blast_Score=134, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6324188, Length=338, Percent_Identity=29.8816568047337, Blast_Score=158, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24645260, Length=344, Percent_Identity=27.0348837209302, Blast_Score=108, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 38333; Mature: 38333

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSPLAEFIRRMPKCELHVHLEGSITPKTLLELATKNGISLPASDLAGVERMFQYEHFLG
CCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLDVYRTCARCLIHGEDFERVAYELAIDLAQQQVRYAEVMLSPAQHMLRNMDFDEILGGV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAGFARAEREMGIVCRPAFDFGRQFSLDQALRAVELAQAGMQYGVVAFSIGGDEANYPPE
HHHHHHHHHHCCEEEECCHHCCCCCCHHHHHHHHHHHHHCHHHCEEEEEECCCCCCCCCH
PFVEVFALAKAVGLHVMAHAGEVAGANSVRGAVEMLGVDRIGHGFRVLEDAELTQFLARR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GDITFDVCPTSNIRTGVVASFDQHPLRQMLDAGLPITLNSDDPVLFDTTVTGEFLLAAER
CCCEEEECCCCCCCCCHHCCCCHHHHHHHHHCCCCEEECCCCCEEEEEECCCCEEEEECC
YDFTIDDICKVARQSAKAAFLPAEQRQQLLLEFDQQQAQLRRELGL
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHSPLAEFIRRMPKCELHVHLEGSITPKTLLELATKNGISLPASDLAGVERMFQYEHFLG
CCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLDVYRTCARCLIHGEDFERVAYELAIDLAQQQVRYAEVMLSPAQHMLRNMDFDEILGGV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAGFARAEREMGIVCRPAFDFGRQFSLDQALRAVELAQAGMQYGVVAFSIGGDEANYPPE
HHHHHHHHHHCCEEEECCHHCCCCCCHHHHHHHHHHHHHCHHHCEEEEEECCCCCCCCCH
PFVEVFALAKAVGLHVMAHAGEVAGANSVRGAVEMLGVDRIGHGFRVLEDAELTQFLARR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GDITFDVCPTSNIRTGVVASFDQHPLRQMLDAGLPITLNSDDPVLFDTTVTGEFLLAAER
CCCEEEECCCCCCCCCHHCCCCHHHHHHHHHCCCCEEECCCCCEEEEEECCCCEEEEECC
YDFTIDDICKVARQSAKAAFLPAEQRQQLLLEFDQQQAQLRRELGL
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA