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The map label for this gene is 159897717

Identifier: 159897717

GI number: 159897717

Start: 1364922

End: 1366547

Strand: Direct

Name: 159897717

Synonym: Haur_1188

Alternate gene names: NA

Gene position: 1364922-1366547 (Clockwise)

Preceding gene: 159897715

Following gene: 159897718

Centisome position: 21.51

GC content: 51.85

Gene sequence:

>1626_bases
ATGAGCCGTCGCATTGCACTTGTTTTTTGTTTGATCTTGCTGGTCGGCACGCCAGTCTATGCCCAAAATGCCTTAACTGG
CCCACCCAACGACCCCGACGCAAATAAACAATGGGTCATTCGCCAACTTGGTTTAGCGTGTGCATGGGAGCATTTGACGG
GTAACTCCGATGTTACTGTGGCCGTGATCGACTCTGGCGTTGATATGAACCACCCCGATTTGGTCGATGTCTTGCGCACC
GACGGCTTTGATGCTGTCGATGGCGATGATGATCCATCGGATGAGAATGGCCACGGAACCCATGTTTCAGGCATTATTGC
CGCCACCATCAACAACAGTAAAGGAATTGCAGGGGTTGCCGGTGGGGGCACGCGCATTTTGCCAATTCGGGTGATGGCTG
CCGATGGTTCGGGCACGAATCAAGATATTATTGCGGGCATTCGCTATGCCGTTAGCAAAAATGTCCAGATCATCAATATG
AGCCTTGGCTCGATGTTACCGCTCGATAGCGAAGATATTGTTGAGGCAATCAAAGAGGCCGATGCCGCTGGCGTACTGGT
GATTATCGCCGCTGGTAATTCGTTTGTGCCCTTGCCCAACTTCGCCTTTGGGGTTGAAGAATTTGCCATGGTCGTGGCCG
CAACTGATCCTGATGATCGCAAAACCGATTTTTCGAACTATGGTAAGTGGATTTCGGTTTCGGCACCAGGGGCAGGCATT
TACTCAACAATGCCCACCTACGATGTGTATATGACCAGTCAGTTGCCTGCTGAAGAACGCTTCAACAAAAACTACGATCA
AATGAGCGGCACATCGCAAGCTACGCCAGTGGTTGCTGGCTTGGCAGCCTTGCTATTTGCCCAACACCCCGATTGGAATG
CCGACCAAGTACGGGCTGAAATCGAAAAAACTGCTGATGATATTTCAGCGCAAAATCCGATTAAGCGCTATGGCCCAATC
ACCTATTTCGAGCCAAGCAACCTTGGCAAAGGCCGTGTCAATGCTTGCAATGCCTTGGGTGGCCCAGTTAAAGGTAGTGC
TGCAGCAGTTGGCGGCCCTGAAGGAAAATCCAATTTAATCATGCTGCTTGGGTTTAGCGCGGTCATGTTGGTAGTTTTGG
GCGGATTAACCGTCTTTTTAATTCGCCGTCGCAAGCACAACGCCCGCCCTGCGGCGATTCCCGCTGGTGGTTTTGCCCCA
CCGCCACCAATTCATTATGATCAAGCAATGGCCCAACAGCAACGCAACCTTGCCTCGCAACCAATCGTCGGATCAACGCC
GCCATTGAACCAGAGTTATGCCCCACCCAGCGCGGCTCCGGCAGGCGGGCCAGCGTGGGGCAAATTAACGGTTGTCCGGG
GAGCCGAATTGAACAAGTTCTATTTGCTGCGTGAAAATCAAATTTTTATTGGCCGTGAAGCCTCGCTTGCCGTGGCAATT
AGCGGTGATAGCACCGTTTCACGTCGCCATACGATCATCTATCGTGATCCTCGTGGCATTGAAATTGAAGATGCAGGCAG
CAGTCATGGCACCAAAATCAACGGCATTCCAGTACAAGGCCGCCAACTGGTTCGACCAGGCGATGTGATCGAAGTTGGGC
AGACCCATTTACGTTTTGAGGGTTAA

Upstream 100 bases:

>100_bases
CAGGCTGTGAGTGTAAGCAAAAGGCAGCCAATAAGCAACTGTTTGAAACGCATGGGGAATCCTCCAGCGTGCTGAGTGTT
TGTCAGGAGGCGATTATATC

Downstream 100 bases:

>100_bases
CATTTGGAACTAGCACTTGCATTGTTGATTATGTTTCTCGGCTTGGTGAGCGTGGTAATTTTGCCAATCTTGCCAGGCGC
AGCCTTGATTTGGCTTGGGG

Product: FHA domain-containing protein

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MSRRIALVFCLILLVGTPVYAQNALTGPPNDPDANKQWVIRQLGLACAWEHLTGNSDVTVAVIDSGVDMNHPDLVDVLRT
DGFDAVDGDDDPSDENGHGTHVSGIIAATINNSKGIAGVAGGGTRILPIRVMAADGSGTNQDIIAGIRYAVSKNVQIINM
SLGSMLPLDSEDIVEAIKEADAAGVLVIIAAGNSFVPLPNFAFGVEEFAMVVAATDPDDRKTDFSNYGKWISVSAPGAGI
YSTMPTYDVYMTSQLPAEERFNKNYDQMSGTSQATPVVAGLAALLFAQHPDWNADQVRAEIEKTADDISAQNPIKRYGPI
TYFEPSNLGKGRVNACNALGGPVKGSAAAVGGPEGKSNLIMLLGFSAVMLVVLGGLTVFLIRRRKHNARPAAIPAGGFAP
PPPIHYDQAMAQQQRNLASQPIVGSTPPLNQSYAPPSAAPAGGPAWGKLTVVRGAELNKFYLLRENQIFIGREASLAVAI
SGDSTVSRRHTIIYRDPRGIEIEDAGSSHGTKINGIPVQGRQLVRPGDVIEVGQTHLRFEG

Sequences:

>Translated_541_residues
MSRRIALVFCLILLVGTPVYAQNALTGPPNDPDANKQWVIRQLGLACAWEHLTGNSDVTVAVIDSGVDMNHPDLVDVLRT
DGFDAVDGDDDPSDENGHGTHVSGIIAATINNSKGIAGVAGGGTRILPIRVMAADGSGTNQDIIAGIRYAVSKNVQIINM
SLGSMLPLDSEDIVEAIKEADAAGVLVIIAAGNSFVPLPNFAFGVEEFAMVVAATDPDDRKTDFSNYGKWISVSAPGAGI
YSTMPTYDVYMTSQLPAEERFNKNYDQMSGTSQATPVVAGLAALLFAQHPDWNADQVRAEIEKTADDISAQNPIKRYGPI
TYFEPSNLGKGRVNACNALGGPVKGSAAAVGGPEGKSNLIMLLGFSAVMLVVLGGLTVFLIRRRKHNARPAAIPAGGFAP
PPPIHYDQAMAQQQRNLASQPIVGSTPPLNQSYAPPSAAPAGGPAWGKLTVVRGAELNKFYLLRENQIFIGREASLAVAI
SGDSTVSRRHTIIYRDPRGIEIEDAGSSHGTKINGIPVQGRQLVRPGDVIEVGQTHLRFEG
>Mature_540_residues
SRRIALVFCLILLVGTPVYAQNALTGPPNDPDANKQWVIRQLGLACAWEHLTGNSDVTVAVIDSGVDMNHPDLVDVLRTD
GFDAVDGDDDPSDENGHGTHVSGIIAATINNSKGIAGVAGGGTRILPIRVMAADGSGTNQDIIAGIRYAVSKNVQIINMS
LGSMLPLDSEDIVEAIKEADAAGVLVIIAAGNSFVPLPNFAFGVEEFAMVVAATDPDDRKTDFSNYGKWISVSAPGAGIY
STMPTYDVYMTSQLPAEERFNKNYDQMSGTSQATPVVAGLAALLFAQHPDWNADQVRAEIEKTADDISAQNPIKRYGPIT
YFEPSNLGKGRVNACNALGGPVKGSAAAVGGPEGKSNLIMLLGFSAVMLVVLGGLTVFLIRRRKHNARPAAIPAGGFAPP
PPIHYDQAMAQQQRNLASQPIVGSTPPLNQSYAPPSAAPAGGPAWGKLTVVRGAELNKFYLLRENQIFIGREASLAVAIS
GDSTVSRRHTIIYRDPRGIEIEDAGSSHGTKINGIPVQGRQLVRPGDVIEVGQTHLRFEG

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI76443679, Length=290, Percent_Identity=27.9310344827586, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324576, Length=249, Percent_Identity=34.136546184739, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319893, Length=330, Percent_Identity=27.2727272727273, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320775, Length=245, Percent_Identity=31.8367346938775, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 57201; Mature: 57070

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50006 FHA_DOMAIN ; PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRIALVFCLILLVGTPVYAQNALTGPPNDPDANKQWVIRQLGLACAWEHLTGNSDVTV
CCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
AVIDSGVDMNHPDLVDVLRTDGFDAVDGDDDPSDENGHGTHVSGIIAATINNSKGIAGVA
EEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCEEEEC
GGGTRILPIRVMAADGSGTNQDIIAGIRYAVSKNVQIINMSLGSMLPLDSEDIVEAIKEA
CCCEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHC
DAAGVLVIIAAGNSFVPLPNFAFGVEEFAMVVAATDPDDRKTDFSNYGKWISVSAPGAGI
CCCCEEEEEECCCCCCCCCCHHHCCCCEEEEEEECCCCCCCCCHHHCCCEEEEECCCCCC
YSTMPTYDVYMTSQLPAEERFNKNYDQMSGTSQATPVVAGLAALLFAQHPDWNADQVRAE
CCCCCCEEEEEECCCCHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
IEKTADDISAQNPIKRYGPITYFEPSNLGKGRVNACNALGGPVKGSAAAVGGPEGKSNLI
HHHHHHHHHCCCCHHHHCCEEEECCCCCCCCCCCHHHCCCCCCCCCEEECCCCCCCCCEE
MLLGFSAVMLVVLGGLTVFLIRRRKHNARPAAIPAGGFAPPPPIHYDQAMAQQQRNLASQ
EEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
PIVGSTPPLNQSYAPPSAAPAGGPAWGKLTVVRGAELNKFYLLRENQIFIGREASLAVAI
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCEEEEECCCEEEEEE
SGDSTVSRRHTIIYRDPRGIEIEDAGSSHGTKINGIPVQGRQLVRPGDVIEVGQTHLRFE
CCCCCCCCCEEEEEECCCCCEEECCCCCCCCEECCCCCCCCEECCCCCEEECCCCEEEEC
G
C
>Mature Secondary Structure 
SRRIALVFCLILLVGTPVYAQNALTGPPNDPDANKQWVIRQLGLACAWEHLTGNSDVTV
CCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
AVIDSGVDMNHPDLVDVLRTDGFDAVDGDDDPSDENGHGTHVSGIIAATINNSKGIAGVA
EEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCEEEEC
GGGTRILPIRVMAADGSGTNQDIIAGIRYAVSKNVQIINMSLGSMLPLDSEDIVEAIKEA
CCCEEEEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHC
DAAGVLVIIAAGNSFVPLPNFAFGVEEFAMVVAATDPDDRKTDFSNYGKWISVSAPGAGI
CCCCEEEEEECCCCCCCCCCHHHCCCCEEEEEEECCCCCCCCCHHHCCCEEEEECCCCCC
YSTMPTYDVYMTSQLPAEERFNKNYDQMSGTSQATPVVAGLAALLFAQHPDWNADQVRAE
CCCCCCEEEEEECCCCHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
IEKTADDISAQNPIKRYGPITYFEPSNLGKGRVNACNALGGPVKGSAAAVGGPEGKSNLI
HHHHHHHHHCCCCHHHHCCEEEECCCCCCCCCCCHHHCCCCCCCCCEEECCCCCCCCCEE
MLLGFSAVMLVVLGGLTVFLIRRRKHNARPAAIPAGGFAPPPPIHYDQAMAQQQRNLASQ
EEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
PIVGSTPPLNQSYAPPSAAPAGGPAWGKLTVVRGAELNKFYLLRENQIFIGREASLAVAI
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCEEEEECCCEEEEEE
SGDSTVSRRHTIIYRDPRGIEIEDAGSSHGTKINGIPVQGRQLVRPGDVIEVGQTHLRFE
CCCCCCCCCEEEEEECCCCCEEECCCCCCCCEECCCCCCCCEECCCCCEEECCCCEEEEC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]