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The map label for this gene is glcK [H]

Identifier: 159897710

GI number: 159897710

Start: 1355675

End: 1356685

Strand: Reverse

Name: glcK [H]

Synonym: Haur_1181

Alternate gene names: 159897710

Gene position: 1356685-1355675 (Counterclockwise)

Preceding gene: 159897711

Following gene: 159897709

Centisome position: 21.38

GC content: 53.31

Gene sequence:

>1011_bases
GTGGATCAACGACAGCGCCGGAACGCCAATGGCTGGCGGCTGGGAGTCGATGTAGGGGGGACGAAAATTGCCACCCTACT
TGTCGATGGCGATAATCGAGTTTGGGCCAGCGTTCAACGCCCAACCGATACCGCAACTCCAGACCATGCCCTCAAGTCTC
TTGCTGATGCGATTTGGGAAACCTTGAAACAAGCCGACCTACCCATTCGGCTCCTTGCGGGCATTGGGATTGGCATTCCA
GGCCAAGTCGATACGCAGAGCGGGATTGTTCGGCACGCCGTCAATCTTGGCTGGCAAGCAGTTGATCTACGTGGATTCAT
CAACGCAACCTTTGGCACGGCCTGTGTGATTGAAAACGATGTTCGAGCAGCAGCATTAGGCATTCAACGCTATTGGTTGG
CTGGTTCGATCGATTCGATGTTATATGTTAGTATAGGCACTGGCATAGCCGCTGGCATGATTCTTGATGGTACTGTCTAC
CGTGGTAGTCACGGAATGGCGGGCGAAATCGGCCATGCACGCTTCGGATCATCAACAATTCGCTGTCGCTGTGGCAATTA
TGGCTGTCTTGAAGCCATCGTTGCTGGGCCAGCAATTGCCAACTATGCACACTCTCTGCTCTCAACATTCCCGCATAGCC
AACTGCATCAACTCGATTCGATAACCACTCCAGCAGTTTACGCCGCTGCTGAAGCTGGCGATGATTTAGCGTTGGCAGTT
GCCCACATGGTTGGCGAACAACTTGCTCAAGCCCTCTATACCATGGTGCTTGCCTACGATTGCGATCATATTGTGCTTGG
AGGCGGTGTTAGCCGCGCAGGCTCAGCCTTCTTCGCACCAATCGAACAAGCACTTGATGTCTTACGTCAGCAAAGTTCTC
TAGCAACATCATTACTTCCGACGGGGCGGGTTAAGCTCTTAGATCGTGATTTTGCTGCTGGTGCATGGGGCGGAATCGCC
TTGCTCGATAGCCAAGCGTTGGCGCGGGTTGCGCAAACGCAACTGGCATAA

Upstream 100 bases:

>100_bases
CTCTGTTACTAGCCAATGAGCTAGGCATTGTTCGGGATTAAGTTCCAGCAAACCACCCCCGACAGGCTTAGCCACTTAGT
TCCTTGTATAGGGGGTTTGC

Downstream 100 bases:

>100_bases
CTCGCCAAGGGATTGGCACAGAATCCCACGGCAAAACCATACCAGTACCACATCGATTTAGGTTGGATTTGGGGAAACCT
ACGGGTTATGGGTCACGCAT

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MDQRQRRNANGWRLGVDVGGTKIATLLVDGDNRVWASVQRPTDTATPDHALKSLADAIWETLKQADLPIRLLAGIGIGIP
GQVDTQSGIVRHAVNLGWQAVDLRGFINATFGTACVIENDVRAAALGIQRYWLAGSIDSMLYVSIGTGIAAGMILDGTVY
RGSHGMAGEIGHARFGSSTIRCRCGNYGCLEAIVAGPAIANYAHSLLSTFPHSQLHQLDSITTPAVYAAAEAGDDLALAV
AHMVGEQLAQALYTMVLAYDCDHIVLGGGVSRAGSAFFAPIEQALDVLRQQSSLATSLLPTGRVKLLDRDFAAGAWGGIA
LLDSQALARVAQTQLA

Sequences:

>Translated_336_residues
MDQRQRRNANGWRLGVDVGGTKIATLLVDGDNRVWASVQRPTDTATPDHALKSLADAIWETLKQADLPIRLLAGIGIGIP
GQVDTQSGIVRHAVNLGWQAVDLRGFINATFGTACVIENDVRAAALGIQRYWLAGSIDSMLYVSIGTGIAAGMILDGTVY
RGSHGMAGEIGHARFGSSTIRCRCGNYGCLEAIVAGPAIANYAHSLLSTFPHSQLHQLDSITTPAVYAAAEAGDDLALAV
AHMVGEQLAQALYTMVLAYDCDHIVLGGGVSRAGSAFFAPIEQALDVLRQQSSLATSLLPTGRVKLLDRDFAAGAWGGIA
LLDSQALARVAQTQLA
>Mature_336_residues
MDQRQRRNANGWRLGVDVGGTKIATLLVDGDNRVWASVQRPTDTATPDHALKSLADAIWETLKQADLPIRLLAGIGIGIP
GQVDTQSGIVRHAVNLGWQAVDLRGFINATFGTACVIENDVRAAALGIQRYWLAGSIDSMLYVSIGTGIAAGMILDGTVY
RGSHGMAGEIGHARFGSSTIRCRCGNYGCLEAIVAGPAIANYAHSLLSTFPHSQLHQLDSITTPAVYAAAEAGDDLALAV
AHMVGEQLAQALYTMVLAYDCDHIVLGGGVSRAGSAFFAPIEQALDVLRQQSSLATSLLPTGRVKLLDRDFAAGAWGGIA
LLDSQALARVAQTQLA

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=198, Percent_Identity=29.7979797979798, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI298566325, Length=198, Percent_Identity=29.7979797979798, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4885285, Length=198, Percent_Identity=29.7979797979798, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI190014632, Length=198, Percent_Identity=29.7979797979798, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786891, Length=307, Percent_Identity=28.0130293159609, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787363, Length=312, Percent_Identity=27.8846153846154, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787878, Length=227, Percent_Identity=29.5154185022026, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082127, Length=243, Percent_Identity=24.2798353909465, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081733, Length=271, Percent_Identity=25.830258302583, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790522, Length=261, Percent_Identity=24.904214559387, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082230, Length=282, Percent_Identity=25.531914893617, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 35371; Mature: 35371

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQRQRRNANGWRLGVDVGGTKIATLLVDGDNRVWASVQRPTDTATPDHALKSLADAIWE
CCCHHCCCCCCEEEEEEECCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
TLKQADLPIRLLAGIGIGIPGQVDTQSGIVRHAVNLGWQAVDLRGFINATFGTACVIEND
HHHHCCCCEEEEHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHCCCCEEEEEECC
VRAAALGIQRYWLAGSIDSMLYVSIGTGIAAGMILDGTVYRGSHGMAGEIGHARFGSSTI
HHHHHHHHHHHHECCCCCCEEEEEECCCHHHCEEECCEEEECCCCCCCCCCCCCCCCCEE
RCRCGNYGCLEAIVAGPAIANYAHSLLSTFPHSQLHQLDSITTPAVYAAAEAGDDLALAV
EEECCCCHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHEEHHCCCCHHHHHH
AHMVGEQLAQALYTMVLAYDCDHIVLGGGVSRAGSAFFAPIEQALDVLRQQSSLATSLLP
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TGRVKLLDRDFAAGAWGGIALLDSQALARVAQTQLA
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDQRQRRNANGWRLGVDVGGTKIATLLVDGDNRVWASVQRPTDTATPDHALKSLADAIWE
CCCHHCCCCCCEEEEEEECCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
TLKQADLPIRLLAGIGIGIPGQVDTQSGIVRHAVNLGWQAVDLRGFINATFGTACVIEND
HHHHCCCCEEEEHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHCCCCEEEEEECC
VRAAALGIQRYWLAGSIDSMLYVSIGTGIAAGMILDGTVYRGSHGMAGEIGHARFGSSTI
HHHHHHHHHHHHECCCCCCEEEEEECCCHHHCEEECCEEEECCCCCCCCCCCCCCCCCEE
RCRCGNYGCLEAIVAGPAIANYAHSLLSTFPHSQLHQLDSITTPAVYAAAEAGDDLALAV
EEECCCCHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHEEHHCCCCHHHHHH
AHMVGEQLAQALYTMVLAYDCDHIVLGGGVSRAGSAFFAPIEQALDVLRQQSSLATSLLP
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TGRVKLLDRDFAAGAWGGIALLDSQALARVAQTQLA
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]