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The map label for this gene is xylR [H]

Identifier: 159897711

GI number: 159897711

Start: 1356745

End: 1357905

Strand: Reverse

Name: xylR [H]

Synonym: Haur_1182

Alternate gene names: 159897711

Gene position: 1357905-1356745 (Counterclockwise)

Preceding gene: 159897712

Following gene: 159897710

Centisome position: 21.4

GC content: 53.32

Gene sequence:

>1161_bases
ATGCAGGGACTGCCCAAGAAAGCCAGTCGGGAGCAAAGCAAGCTTCACAACTACCGACTTGTCTTCAAAGCCATCTACGA
CGGTGGCGCGATTAGTCGGGTGGATGTAGCACGCTTAACCAACCTCACGCCAACCACAGTTTCGAGTAACGTCGCGATCC
TACTCGAAGAAGAATTGGTGCAAGAAGTCGGGTTAGCGCCCTCTGGTGGTGGAAAGCCAGCGACATTGCTGAGCGTATTG
GATGATGGTCGCCACTTGATAGGTTTGGATGTTGCGGGACACGAACTGCGGGGCACGATCATCAACTTACGTGGGGCAAT
TCGCCAACGCCAAACGCTCGCGCTGAATGGGGGCAATGTTCTCGAACAATTGTATCAACTGATTGATCAATTGCTAGCGA
ACACCCACAGCCCAGTTCTCGGAATTGGCATCGGCGCACCAGGGGTCATTAACACCACCGCTGGAGTTGTCCAACAAGCA
GTCAACCTTGGTTGGCACAATCTCGCACTCCGCGATTTGTTGGGCAAGCGTTATGGGTTACCGGTCTATTTGGCCAACGA
TAGTCATGTAACGGCGATTGCTGAACACACGTTTGGCAGCCAGCGCAACGCGGCAAACCTTGTGGTGATCAACGTTGGGC
GTGGGATCGGCGCAGGCATTTTTATCAATGGTCGAATTGTTGGTGGTGATGCTTGGGGAGCGGGTGAAATCGGTCACGTC
GTGGTTCAACCTCATGGAACTCTCTGTCGTTGTGGCCATTATGGCTGCCTCGAAACTGTTGCCAGCACAAGTGCGCTGCT
AACAAAACTTGATGCAACCCAACCACAATCACAGCCATGGACGATTGCCGAGGTCCAAGCGGCCTTAGCCGCGAATGATC
CGACTGTCCGAGCCTTGGTTGACGAAGCTGCCTACTATCTTGGCATCGCCATTGCAAATGTAGTGGGTTTGCTCAACGCT
CAATCAATTATCCTTGCTGGGTCGCTGGCCCAACTTGGCAATGATTTACTCCAACCGTTACGCCGTTCGCTAGCACAACA
CGCTTTGCAGACTTTGGTCGCCGCCACCGATGTGCAAGTGAGCACCCTCGGCAGCGATATCGTTACCCTAGGTGCAGCAG
CTCTGTTACTAGCCAATGAGCTAGGCATTGTTCGGGATTAA

Upstream 100 bases:

>100_bases
TGATACCTAAAGCTCAGCCTTTTGCCCCTCGCAAAGCTGCGCTTGACAAATTGAGCCGCTTGTGGGATACTCTCACTTAG
TAAATTCATTGGAATAAGTT

Downstream 100 bases:

>100_bases
GTTCCAGCAAACCACCCCCGACAGGCTTAGCCACTTAGTTCCTTGTATAGGGGGTTTGCGTGGATCAACGACAGCGCCGG
AACGCCAATGGCTGGCGGCT

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MQGLPKKASREQSKLHNYRLVFKAIYDGGAISRVDVARLTNLTPTTVSSNVAILLEEELVQEVGLAPSGGGKPATLLSVL
DDGRHLIGLDVAGHELRGTIINLRGAIRQRQTLALNGGNVLEQLYQLIDQLLANTHSPVLGIGIGAPGVINTTAGVVQQA
VNLGWHNLALRDLLGKRYGLPVYLANDSHVTAIAEHTFGSQRNAANLVVINVGRGIGAGIFINGRIVGGDAWGAGEIGHV
VVQPHGTLCRCGHYGCLETVASTSALLTKLDATQPQSQPWTIAEVQAALAANDPTVRALVDEAAYYLGIAIANVVGLLNA
QSIILAGSLAQLGNDLLQPLRRSLAQHALQTLVAATDVQVSTLGSDIVTLGAAALLLANELGIVRD

Sequences:

>Translated_386_residues
MQGLPKKASREQSKLHNYRLVFKAIYDGGAISRVDVARLTNLTPTTVSSNVAILLEEELVQEVGLAPSGGGKPATLLSVL
DDGRHLIGLDVAGHELRGTIINLRGAIRQRQTLALNGGNVLEQLYQLIDQLLANTHSPVLGIGIGAPGVINTTAGVVQQA
VNLGWHNLALRDLLGKRYGLPVYLANDSHVTAIAEHTFGSQRNAANLVVINVGRGIGAGIFINGRIVGGDAWGAGEIGHV
VVQPHGTLCRCGHYGCLETVASTSALLTKLDATQPQSQPWTIAEVQAALAANDPTVRALVDEAAYYLGIAIANVVGLLNA
QSIILAGSLAQLGNDLLQPLRRSLAQHALQTLVAATDVQVSTLGSDIVTLGAAALLLANELGIVRD
>Mature_386_residues
MQGLPKKASREQSKLHNYRLVFKAIYDGGAISRVDVARLTNLTPTTVSSNVAILLEEELVQEVGLAPSGGGKPATLLSVL
DDGRHLIGLDVAGHELRGTIINLRGAIRQRQTLALNGGNVLEQLYQLIDQLLANTHSPVLGIGIGAPGVINTTAGVVQQA
VNLGWHNLALRDLLGKRYGLPVYLANDSHVTAIAEHTFGSQRNAANLVVINVGRGIGAGIFINGRIVGGDAWGAGEIGHV
VVQPHGTLCRCGHYGCLETVASTSALLTKLDATQPQSQPWTIAEVQAALAANDPTVRALVDEAAYYLGIAIANVVGLLNA
QSIILAGSLAQLGNDLLQPLRRSLAQHALQTLVAATDVQVSTLGSDIVTLGAAALLLANELGIVRD

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI4885285, Length=314, Percent_Identity=27.3885350318471, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI190014632, Length=314, Percent_Identity=27.3885350318471, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI298566325, Length=314, Percent_Identity=27.3885350318471, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI298566315, Length=314, Percent_Identity=27.3885350318471, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786891, Length=355, Percent_Identity=28.4507042253521, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1787878, Length=381, Percent_Identity=28.8713910761155, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87082127, Length=345, Percent_Identity=25.7971014492754, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87081733, Length=202, Percent_Identity=29.2079207920792, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082230, Length=244, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787363, Length=205, Percent_Identity=26.8292682926829, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790522, Length=254, Percent_Identity=24.4094488188976, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 40360; Mature: 40360

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLPKKASREQSKLHNYRLVFKAIYDGGAISRVDVARLTNLTPTTVSSNVAILLEEELV
CCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCEEEEEHHHHH
QEVGLAPSGGGKPATLLSVLDDGRHLIGLDVAGHELRGTIINLRGAIRQRQTLALNGGNV
HHHCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHCEEEEHHHHHHHCCEEEECCCHH
LEQLYQLIDQLLANTHSPVLGIGIGAPGVINTTAGVVQQAVNLGWHNLALRDLLGKRYGL
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PVYLANDSHVTAIAEHTFGSQRNAANLVVINVGRGIGAGIFINGRIVGGDAWGAGEIGHV
EEEEECCCCEEEEEHHCCCCCCCCCEEEEEECCCCCCCCEEEECEEEECCCCCCCCCCEE
VVQPHGTLCRCGHYGCLETVASTSALLTKLDATQPQSQPWTIAEVQAALAANDPTVRALV
EECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHH
DEAAYYLGIAIANVVGLLNAQSIILAGSLAQLGNDLLQPLRRSLAQHALQTLVAATDVQV
HHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
STLGSDIVTLGAAALLLANELGIVRD
HHHCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQGLPKKASREQSKLHNYRLVFKAIYDGGAISRVDVARLTNLTPTTVSSNVAILLEEELV
CCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCEEEEEHHHHH
QEVGLAPSGGGKPATLLSVLDDGRHLIGLDVAGHELRGTIINLRGAIRQRQTLALNGGNV
HHHCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHCEEEEHHHHHHHCCEEEECCCHH
LEQLYQLIDQLLANTHSPVLGIGIGAPGVINTTAGVVQQAVNLGWHNLALRDLLGKRYGL
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PVYLANDSHVTAIAEHTFGSQRNAANLVVINVGRGIGAGIFINGRIVGGDAWGAGEIGHV
EEEEECCCCEEEEEHHCCCCCCCCCEEEEEECCCCCCCCEEEECEEEECCCCCCCCCCEE
VVQPHGTLCRCGHYGCLETVASTSALLTKLDATQPQSQPWTIAEVQAALAANDPTVRALV
EECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHH
DEAAYYLGIAIANVVGLLNAQSIILAGSLAQLGNDLLQPLRRSLAQHALQTLVAATDVQV
HHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
STLGSDIVTLGAAALLLANELGIVRD
HHHCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]