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The map label for this gene is nagA [H]

Identifier: 159897704

GI number: 159897704

Start: 1348367

End: 1349506

Strand: Reverse

Name: nagA [H]

Synonym: Haur_1175

Alternate gene names: 159897704

Gene position: 1349506-1348367 (Counterclockwise)

Preceding gene: 159897705

Following gene: 159897703

Centisome position: 21.26

GC content: 53.86

Gene sequence:

>1140_bases
ATGAGCAGCCTACGTTTTGAAAATGCCACGATCTATACGCCAGAGCTAAGTGCTGCGCGTAGTTTGGCGATTGCCAATGG
TCATGTGGCTGAGGCTGCTCCTACAGCGCCCTGCTACGATCTGACTGATCTGATTGTTGTGCCAGGTTTGATCGATTTGC
AACTGAATGGGGCATTTGGCCACGATTTCACCAGCGATCCTCATACGATTGGTGCGGTTGCTGCTGGCTTACCGCAATAT
GGCGTGACAGCATTTTTGCCAACGATCATTACTTCACCGCTGAGTCAAGTTGCGGCGGCTCAACAGGTGGTGCAACAGGG
CAATTTTACTGGTTCGCGGGTATTGGGGTTGCATCTCGAAGGGCCGTTTCTCAACCCAGCCAAGCGTGGTGCGCATAATC
CCAGCCATTTGCAAAACCCCAGTTTAGCGGCGATTGAAACTTGGTCGCCAGCCAATGGCGTGCGTTTGGTAACTTTGGCT
CCTGAACTTGATGCTGCCGACGAACTCATTCGAGCATTGGTTGAGCGGGGAGTGGTGGTCAGTGCTGGCCATTCCGAGGC
CACATTTGAAGAAGCTGAGGCTGGTTTCAATCAAGGCATTCGCGCGGTAACCCATTTGTTCAACGCCATGCCAGCCTTGC
ACCATCGCGAACCAGGTTTAGCCGGAGCCGCCTTGAGCGATCAACGGATCACCATGGGCTTGATTCCCGATGGCGTACAC
GTTCATGCAGGCTTGGTGCGCCATATTTGGCACAGTGCCAGTCAACGGATTGCAATTGTCAGCGATGCCCAAGCTGCGCT
CGGCATGCCCGACGGCGAATATCTGCTTGGCGATACAACCCTGACCGTAGCCAACGGTGAGGCTCGGCGCAGCGATGGCC
GTTTGGCGGGCAGCGTGTTGGCGATGGATCAAGCTTTACGCAACATTCATGCGTGGACGAACAGCCCGCTTGAGCAGATT
CTGCCAGCCTTTACCACGATTCCGGCCAATTTGTTGGGCTTAGCTCACTATGGCCGGATTGCAATCAATAACCCTGCTGA
TTTAGTCATTTTTGATCAGCAGCACTATCAGGTTGTCGCCACACTTGTGGGCGGCAACATCGTCTATGGTTCTACAACCT
TGGAGCAACGTCAATGCTAA

Upstream 100 bases:

>100_bases
GCGATGCTGGCCCCGTTGAGTTTTATCAACGCACAGTTGGCGCAATTGTCATCCCCGATTCGACTCCTGGGGTGTATCGT
GGGATGTTGCAAGGGGACGC

Downstream 100 bases:

>100_bases
CCCAAAGCCATCTTTATCGCGAAATTTATGAGCAACCCCAATCGTTGGCACGGCTGCTTGAGGCCGAAAAAGCGACGGTT
GCCAAATTGGCGGCGGCCAT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSSLRFENATIYTPELSAARSLAIANGHVAEAAPTAPCYDLTDLIVVPGLIDLQLNGAFGHDFTSDPHTIGAVAAGLPQY
GVTAFLPTIITSPLSQVAAAQQVVQQGNFTGSRVLGLHLEGPFLNPAKRGAHNPSHLQNPSLAAIETWSPANGVRLVTLA
PELDAADELIRALVERGVVVSAGHSEATFEEAEAGFNQGIRAVTHLFNAMPALHHREPGLAGAALSDQRITMGLIPDGVH
VHAGLVRHIWHSASQRIAIVSDAQAALGMPDGEYLLGDTTLTVANGEARRSDGRLAGSVLAMDQALRNIHAWTNSPLEQI
LPAFTTIPANLLGLAHYGRIAINNPADLVIFDQQHYQVVATLVGGNIVYGSTTLEQRQC

Sequences:

>Translated_379_residues
MSSLRFENATIYTPELSAARSLAIANGHVAEAAPTAPCYDLTDLIVVPGLIDLQLNGAFGHDFTSDPHTIGAVAAGLPQY
GVTAFLPTIITSPLSQVAAAQQVVQQGNFTGSRVLGLHLEGPFLNPAKRGAHNPSHLQNPSLAAIETWSPANGVRLVTLA
PELDAADELIRALVERGVVVSAGHSEATFEEAEAGFNQGIRAVTHLFNAMPALHHREPGLAGAALSDQRITMGLIPDGVH
VHAGLVRHIWHSASQRIAIVSDAQAALGMPDGEYLLGDTTLTVANGEARRSDGRLAGSVLAMDQALRNIHAWTNSPLEQI
LPAFTTIPANLLGLAHYGRIAINNPADLVIFDQQHYQVVATLVGGNIVYGSTTLEQRQC
>Mature_378_residues
SSLRFENATIYTPELSAARSLAIANGHVAEAAPTAPCYDLTDLIVVPGLIDLQLNGAFGHDFTSDPHTIGAVAAGLPQYG
VTAFLPTIITSPLSQVAAAQQVVQQGNFTGSRVLGLHLEGPFLNPAKRGAHNPSHLQNPSLAAIETWSPANGVRLVTLAP
ELDAADELIRALVERGVVVSAGHSEATFEEAEAGFNQGIRAVTHLFNAMPALHHREPGLAGAALSDQRITMGLIPDGVHV
HAGLVRHIWHSASQRIAIVSDAQAALGMPDGEYLLGDTTLTVANGEARRSDGRLAGSVLAMDQALRNIHAWTNSPLEQIL
PAFTTIPANLLGLAHYGRIAINNPADLVIFDQQHYQVVATLVGGNIVYGSTTLEQRQC

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=384, Percent_Identity=35.4166666666667, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI224922791, Length=379, Percent_Identity=35.6200527704486, Blast_Score=190, Evalue=2e-48,
Organism=Escherichia coli, GI1786892, Length=348, Percent_Identity=36.2068965517241, Blast_Score=195, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17553768, Length=353, Percent_Identity=39.0934844192635, Blast_Score=197, Evalue=8e-51,
Organism=Drosophila melanogaster, GI19920392, Length=388, Percent_Identity=34.5360824742268, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI281361140, Length=402, Percent_Identity=33.5820895522388, Blast_Score=202, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40027; Mature: 39896

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLRFENATIYTPELSAARSLAIANGHVAEAAPTAPCYDLTDLIVVPGLIDLQLNGAFG
CCCCCCCCCEEECCCHHHHHEEEECCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCCCC
HDFTSDPHTIGAVAAGLPQYGVTAFLPTIITSPLSQVAAAQQVVQQGNFTGSRVLGLHLE
CCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GPFLNPAKRGAHNPSHLQNPSLAAIETWSPANGVRLVTLAPELDAADELIRALVERGVVV
CCCCCHHHHCCCCCHHCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEE
SAGHSEATFEEAEAGFNQGIRAVTHLFNAMPALHHREPGLAGAALSDQRITMGLIPDGVH
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCH
VHAGLVRHIWHSASQRIAIVSDAQAALGMPDGEYLLGDTTLTVANGEARRSDGRLAGSVL
HHHHHHHHHHHCCCCEEEEEECCHHHCCCCCCCEEECCEEEEEECCCCCCCCCCHHHHHH
AMDQALRNIHAWTNSPLEQILPAFTTIPANLLGLAHYGRIAINNPADLVIFDQQHYQVVA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEECCCHHEEEE
TLVGGNIVYGSTTLEQRQC
EECCCEEEECCCCHHHCCC
>Mature Secondary Structure 
SSLRFENATIYTPELSAARSLAIANGHVAEAAPTAPCYDLTDLIVVPGLIDLQLNGAFG
CCCCCCCCEEECCCHHHHHEEEECCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCCCC
HDFTSDPHTIGAVAAGLPQYGVTAFLPTIITSPLSQVAAAQQVVQQGNFTGSRVLGLHLE
CCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GPFLNPAKRGAHNPSHLQNPSLAAIETWSPANGVRLVTLAPELDAADELIRALVERGVVV
CCCCCHHHHCCCCCHHCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEE
SAGHSEATFEEAEAGFNQGIRAVTHLFNAMPALHHREPGLAGAALSDQRITMGLIPDGVH
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCH
VHAGLVRHIWHSASQRIAIVSDAQAALGMPDGEYLLGDTTLTVANGEARRSDGRLAGSVL
HHHHHHHHHHHCCCCEEEEEECCHHHCCCCCCCEEECCEEEEEECCCCCCCCCCHHHHHH
AMDQALRNIHAWTNSPLEQILPAFTTIPANLLGLAHYGRIAINNPADLVIFDQQHYQVVA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEECCCHHEEEE
TLVGGNIVYGSTTLEQRQC
EECCCEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]