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The map label for this gene is glmS [H]

Identifier: 159897703

GI number: 159897703

Start: 1347327

End: 1348373

Strand: Reverse

Name: glmS [H]

Synonym: Haur_1174

Alternate gene names: 159897703

Gene position: 1348373-1347327 (Counterclockwise)

Preceding gene: 159897704

Following gene: 159897702

Centisome position: 21.25

GC content: 53.58

Gene sequence:

>1047_bases
ATGCTAACCCAAAGCCATCTTTATCGCGAAATTTATGAGCAACCCCAATCGTTGGCACGGCTGCTTGAGGCCGAAAAAGC
GACGGTTGCCAAATTGGCGGCGGCCATTCGCGAACGAAATATTAGCCAAATTGTGATTGCCGCGCGTGGCACCAGCGATA
ATGCTGCTCGCTACGCCCAATATTTGCTTGGCTCACTCAACGGCATCTTAGTCACCTTGGCTACACCCAGCCTGTTCTCA
ATCTATCAACGCCCGCCGGTTTTGGGCAATGTTTGTGTCCTGGGCATCAGCCAAAGTGGCAAAAGCCCCGACATCGTGGC
CGTGCTGACCGAAGCTCGCAAGCAAGGCGCACTCACCGCCGCAATCACCAACAAAACCGATTCGCCCTTAGCGCAAGCTG
GCGATTTTGTGATCGATTTACACGCTGGCGAGGAATTGGCGGTTGCCGCAACCAAAAGCTATACCGCTCAACTCGCGGCG
ATTGCGCTGCTCAGCACTGCCTTGGCCGATGATTCGGCCATGAACCAAGCCTTAGAGCGTTTGCCCCGCGTTGTTGGCGA
CACCCTGAGCAACTTGCCAGATATGGCGAATGTGGTGCAGCGCTATCGTTACATGCAGCAATGCGTGGTGATTGGCCGTG
GCTACAATTATTCAACTGCCTTTGAATTGGCGCTCAAGCTCAAAGAATTAACCTATACGATTGTGCAGCCCTACAGCAGC
GCCGACTTTTTGCATGGCCCCGTGGCAGTGCTCGAACCTGGTTTTCCGGTGATTGTGATTGCACCAAGTGGTCAGATGTT
GCCTGAAATGCAAAGTTTCATCCAAACTATTCGCGAGCGTGGCGCAGAAATTCTGGCGATCAGCGATGACCACGATACCT
TGCGCTTGAGCCGCACATCCTTGCGCACACCAGCTGGTTTGCCTGAATGGCTCTCGCCAATTATCAACATTGTGCCTGGC
CAACTGCTGGCCTTGCATTTAGCCCACACCCGCGATTTTGATGTTGATCAGCCACGTGGTTTGCGCAAAGTTACCGAAAC
CCGCTAA

Upstream 100 bases:

>100_bases
CTGCTGATTTAGTCATTTTTGATCAGCAGCACTATCAGGTTGTCGCCACACTTGTGGGCGGCAACATCGTCTATGGTTCT
ACAACCTTGGAGCAACGTCA

Downstream 100 bases:

>100_bases
TTGTTCAATTACTCTCCATCCACGAAGCCTTGCCTTTGGGCAGGGCTTTCAGTTTGTAGCCAAAAAAGGCGAATCTATGC
TACAGTAGGATAATTAAGCA

Product: glutamine--fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MLTQSHLYREIYEQPQSLARLLEAEKATVAKLAAAIRERNISQIVIAARGTSDNAARYAQYLLGSLNGILVTLATPSLFS
IYQRPPVLGNVCVLGISQSGKSPDIVAVLTEARKQGALTAAITNKTDSPLAQAGDFVIDLHAGEELAVAATKSYTAQLAA
IALLSTALADDSAMNQALERLPRVVGDTLSNLPDMANVVQRYRYMQQCVVIGRGYNYSTAFELALKLKELTYTIVQPYSS
ADFLHGPVAVLEPGFPVIVIAPSGQMLPEMQSFIQTIRERGAEILAISDDHDTLRLSRTSLRTPAGLPEWLSPIINIVPG
QLLALHLAHTRDFDVDQPRGLRKVTETR

Sequences:

>Translated_348_residues
MLTQSHLYREIYEQPQSLARLLEAEKATVAKLAAAIRERNISQIVIAARGTSDNAARYAQYLLGSLNGILVTLATPSLFS
IYQRPPVLGNVCVLGISQSGKSPDIVAVLTEARKQGALTAAITNKTDSPLAQAGDFVIDLHAGEELAVAATKSYTAQLAA
IALLSTALADDSAMNQALERLPRVVGDTLSNLPDMANVVQRYRYMQQCVVIGRGYNYSTAFELALKLKELTYTIVQPYSS
ADFLHGPVAVLEPGFPVIVIAPSGQMLPEMQSFIQTIRERGAEILAISDDHDTLRLSRTSLRTPAGLPEWLSPIINIVPG
QLLALHLAHTRDFDVDQPRGLRKVTETR
>Mature_348_residues
MLTQSHLYREIYEQPQSLARLLEAEKATVAKLAAAIRERNISQIVIAARGTSDNAARYAQYLLGSLNGILVTLATPSLFS
IYQRPPVLGNVCVLGISQSGKSPDIVAVLTEARKQGALTAAITNKTDSPLAQAGDFVIDLHAGEELAVAATKSYTAQLAA
IALLSTALADDSAMNQALERLPRVVGDTLSNLPDMANVVQRYRYMQQCVVIGRGYNYSTAFELALKLKELTYTIVQPYSS
ADFLHGPVAVLEPGFPVIVIAPSGQMLPEMQSFIQTIRERGAEILAISDDHDTLRLSRTSLRTPAGLPEWLSPIINIVPG
QLLALHLAHTRDFDVDQPRGLRKVTETR

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=356, Percent_Identity=29.4943820224719, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI4826742, Length=354, Percent_Identity=29.3785310734463, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI1790167, Length=356, Percent_Identity=30.6179775280899, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI87082251, Length=331, Percent_Identity=25.6797583081571, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17539970, Length=358, Percent_Identity=27.3743016759777, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17532899, Length=358, Percent_Identity=26.536312849162, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17532897, Length=358, Percent_Identity=26.536312849162, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6322745, Length=359, Percent_Identity=27.2980501392758, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323731, Length=357, Percent_Identity=23.8095238095238, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357745, Length=359, Percent_Identity=28.133704735376, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 37814; Mature: 37814

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTQSHLYREIYEQPQSLARLLEAEKATVAKLAAAIRERNISQIVIAARGTSDNAARYAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
YLLGSLNGILVTLATPSLFSIYQRPPVLGNVCVLGISQSGKSPDIVAVLTEARKQGALTA
HHHHCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEE
AITNKTDSPLAQAGDFVIDLHAGEELAVAATKSYTAQLAAIALLSTALADDSAMNQALER
EECCCCCCCHHHCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LPRVVGDTLSNLPDMANVVQRYRYMQQCVVIGRGYNYSTAFELALKLKELTYTIVQPYSS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
ADFLHGPVAVLEPGFPVIVIAPSGQMLPEMQSFIQTIRERGAEILAISDDHDTLRLSRTS
CCCCCCCHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEHHH
LRTPAGLPEWLSPIINIVPGQLLALHLAHTRDFDVDQPRGLRKVTETR
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MLTQSHLYREIYEQPQSLARLLEAEKATVAKLAAAIRERNISQIVIAARGTSDNAARYAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
YLLGSLNGILVTLATPSLFSIYQRPPVLGNVCVLGISQSGKSPDIVAVLTEARKQGALTA
HHHHCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEE
AITNKTDSPLAQAGDFVIDLHAGEELAVAATKSYTAQLAAIALLSTALADDSAMNQALER
EECCCCCCCHHHCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LPRVVGDTLSNLPDMANVVQRYRYMQQCVVIGRGYNYSTAFELALKLKELTYTIVQPYSS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
ADFLHGPVAVLEPGFPVIVIAPSGQMLPEMQSFIQTIRERGAEILAISDDHDTLRLSRTS
CCCCCCCHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEHHH
LRTPAGLPEWLSPIINIVPGQLLALHLAHTRDFDVDQPRGLRKVTETR
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA