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The map label for this gene is yycF [H]

Identifier: 159897434

GI number: 159897434

Start: 1036822

End: 1037538

Strand: Direct

Name: yycF [H]

Synonym: Haur_0905

Alternate gene names: 159897434

Gene position: 1036822-1037538 (Clockwise)

Preceding gene: 159897430

Following gene: 159897435

Centisome position: 16.34

GC content: 51.6

Gene sequence:

>717_bases
ATGGCTGAGCATGTGCCGACAATTTTGGTGGTTGAAGATGCTGTCGATTTGGCCGAAGTGTTGGTGCGCGAACTGAGCAA
CTTGGGTTATCAGGTCTGGCATGCTGCTGATGGCCGAACAGCTCTAAGTTTACACCAGCAACATCAACCAGATTTAGTGA
TTTTAGATTGGATGTTGCCGCAACTTGATGGTTTAGAGGTGTTGCGCACGATTCGCCAAACCAAATCGACCCCGGTGCTG
ATGTTAACAGCGCGTAGCGAAGAAACCGATTTGGTGGTGGGCTTGGAATTGGGTGCTGATGATTATTTGACCAAACCATT
TGGCATGCGCGAACTGATTGCCAGAGTACGAGCCTTGTTGCGCCGCGATCAGCGGATTCAGCAGTTGTTGCAGGCCGATG
CCCAACCAGCGACCGAGGTCTTGCGCTATGGCGATTTGGTGCTTGACCCGCATTTGCACATTGTTGCCTTGCGTCAGCAG
GAGCTTGATTTGACCCCAACTGAGTTTGCAATTCTCGATTTGTTGTTGCGTAACCCAGGCCGAGCCTTTAGCCGCAATTA
CTTGCTCGATACGATTTGGGGTCAAAGTTATGTTGGCGGCGATCGCTCGGTCGATAATGCCATGCTGCGGTTGCGCAAAA
AATTGGCCGATTTTGGCGATGCAATCGAGACGGTTTGGGGCTTGGGCTATCGTTTGCAGGCGGAAGCACCACGATGA

Upstream 100 bases:

>100_bases
CTTTGAGCAACTGGCTGAAAGGCTGACTAGCTAAAATCTGCTGACCGATAGCGGTTAGATCATCACTCATTTGAACCTCA
CACAGAATAAGGATTTGGCG

Downstream 100 bases:

>100_bases
TGAAGTTTTGGTTGCGCTGGTATGGGCAGGCGGAGCTTTGGCGAGCGTTTGCCATAATGCTGCTGTTCGATGGCTTGTGC
TTAGCAATCTTGCTCGCGAT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MAEHVPTILVVEDAVDLAEVLVRELSNLGYQVWHAADGRTALSLHQQHQPDLVILDWMLPQLDGLEVLRTIRQTKSTPVL
MLTARSEETDLVVGLELGADDYLTKPFGMRELIARVRALLRRDQRIQQLLQADAQPATEVLRYGDLVLDPHLHIVALRQQ
ELDLTPTEFAILDLLLRNPGRAFSRNYLLDTIWGQSYVGGDRSVDNAMLRLRKKLADFGDAIETVWGLGYRLQAEAPR

Sequences:

>Translated_238_residues
MAEHVPTILVVEDAVDLAEVLVRELSNLGYQVWHAADGRTALSLHQQHQPDLVILDWMLPQLDGLEVLRTIRQTKSTPVL
MLTARSEETDLVVGLELGADDYLTKPFGMRELIARVRALLRRDQRIQQLLQADAQPATEVLRYGDLVLDPHLHIVALRQQ
ELDLTPTEFAILDLLLRNPGRAFSRNYLLDTIWGQSYVGGDRSVDNAMLRLRKKLADFGDAIETVWGLGYRLQAEAPR
>Mature_237_residues
AEHVPTILVVEDAVDLAEVLVRELSNLGYQVWHAADGRTALSLHQQHQPDLVILDWMLPQLDGLEVLRTIRQTKSTPVLM
LTARSEETDLVVGLELGADDYLTKPFGMRELIARVRALLRRDQRIQQLLQADAQPATEVLRYGDLVLDPHLHIVALRQQE
LDLTPTEFAILDLLLRNPGRAFSRNYLLDTIWGQSYVGGDRSVDNAMLRLRKKLADFGDAIETVWGLGYRLQAEAPR

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=239, Percent_Identity=38.9121338912134, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=39.6551724137931, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=38.2608695652174, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=42.0353982300885, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=37.9310344827586, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=38.4955752212389, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=37.9912663755458, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=35.8078602620087, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=36.6812227074236, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=32.2033898305085, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=34.5132743362832, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=34.6320346320346, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=38.2608695652174, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=32.7659574468085, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788550, Length=129, Percent_Identity=34.8837209302326, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788191, Length=126, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787487, Length=100, Percent_Identity=40, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=148, Percent_Identity=32.4324324324324, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26931; Mature: 26800

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHVPTILVVEDAVDLAEVLVRELSNLGYQVWHAADGRTALSLHQQHQPDLVILDWMLP
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCCEEEEECCCC
QLDGLEVLRTIRQTKSTPVLMLTARSEETDLVVGLELGADDYLTKPFGMRELIARVRALL
CCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCHHHCCCCCHHHHHHHHHHHH
RRDQRIQQLLQADAQPATEVLRYGDLVLDPHLHIVALRQQELDLTPTEFAILDLLLRNPG
HHHHHHHHHHHCCCCHHHHHHHHCCEEECCCEEEEEEEHHCCCCCCHHHHHHHHHHHCCC
RAFSRNYLLDTIWGQSYVGGDRSVDNAMLRLRKKLADFGDAIETVWGLGYRLQAEAPR
CHHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
>Mature Secondary Structure 
AEHVPTILVVEDAVDLAEVLVRELSNLGYQVWHAADGRTALSLHQQHQPDLVILDWMLP
CCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCCEEEEECCCC
QLDGLEVLRTIRQTKSTPVLMLTARSEETDLVVGLELGADDYLTKPFGMRELIARVRALL
CCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCHHHCCCCCHHHHHHHHHHHH
RRDQRIQQLLQADAQPATEVLRYGDLVLDPHLHIVALRQQELDLTPTEFAILDLLLRNPG
HHHHHHHHHHHCCCCHHHHHHHHCCEEECCCEEEEEEEHHCCCCCCHHHHHHHHHHHCCC
RAFSRNYLLDTIWGQSYVGGDRSVDNAMLRLRKKLADFGDAIETVWGLGYRLQAEAPR
CHHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]