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The map label for this gene is prsA [H]

Identifier: 159897379

GI number: 159897379

Start: 959741

End: 960688

Strand: Reverse

Name: prsA [H]

Synonym: Haur_0850

Alternate gene names: 159897379

Gene position: 960688-959741 (Counterclockwise)

Preceding gene: 159897380

Following gene: 159897378

Centisome position: 15.14

GC content: 46.94

Gene sequence:

>948_bases
ATGCGACGACACGCCCAGTGGTTGCTGCTCTGTTTGGTAATCGCAATCCTAGCAGGCTGTGGTAGTGAAATTACTACCAG
CCAATCCAAAGTCTTGGTTGAGGTTGGTAATTCCTCGATCACCGAAGCAGAATTTACCACCTTTTTGGATTTAAATTCCA
ATATTATCAACCAAAATGCCAGTGGCCTTGATGCCAATACCACCCGCCAACAACTTTTAGATCAAATGATTTTACAAAAA
GTGATTTTAGAAGAAAGCGCCAAGCTTGGGGCGGGCATCGATAGCGTTTCAGCTGAACAAACTACTATGATGATCGATCA
GGCAGTTGGCAAGGAAAAACCAACCTATGCCGATTACGAAGCTTTTGCCAAAGAAAATCGCTTTGGTACGGTTGAAAGTA
TGCGAGCCTATGTGGCCCAAATTTTGACCTACGAAAGCTATGCCCAAAAGCTCGAAGTCCCCAGCGCAACCCCCCAATTC
CACCTGTTCCATATTTTGCTTTCAAGCGATACGGTCAGCGAAAGTGTGGCACTTGAGCAAGCCAACCAGGTGCTAGCTCA
ACTAAAAACGGGCGAAGATTTCTCAATCCTCGCCCAACAATACTCGGCAGACCCTGGCAGCGGCAGCAACGGCGGCGACC
TTGGCTGGTACACCCAAGAGCAATATGCCGGCTTTGTGCCCGAATTTGCGGCGGCGCTGAATACGCTCGAAATTGGTCAA
TTGAGCGAACCAGTGAAAACGCAATTCGGCTATCACATCATCAAAATTACCGAAAGCCGCAATGCGATTAGCTTTGGCAC
ATTCCAAGAATTAATGGACTCACCCGAAGGCAATGCCTATATCCAAAGCAAAGTCGAAGAATATCGCAAAAATGATTTGA
TCAAAAATTACGTGCGCGCCGAGGAAGTGCCCTTCCCTGAATCAGTCACCGTTTTCCAAGATCAATAA

Upstream 100 bases:

>100_bases
GAACTACGACTGTCTCGCTTGGCGTTTGACAAGCGGCCATGGCTGCGGTATCAATGAGATATATAATTTAGCATTTCAAG
AATGTGGAGGACTTTCGCTC

Downstream 100 bases:

>100_bases
TCAGAGCAATGCCAATGGGCGTTACGACAGGATGCATCGCTCATCCTGTCGCTCTTTATTTAAGGAGCAATGATGTTAAG
CCAACTTCTTACGCAATTGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MRRHAQWLLLCLVIAILAGCGSEITTSQSKVLVEVGNSSITEAEFTTFLDLNSNIINQNASGLDANTTRQQLLDQMILQK
VILEESAKLGAGIDSVSAEQTTMMIDQAVGKEKPTYADYEAFAKENRFGTVESMRAYVAQILTYESYAQKLEVPSATPQF
HLFHILLSSDTVSESVALEQANQVLAQLKTGEDFSILAQQYSADPGSGSNGGDLGWYTQEQYAGFVPEFAAALNTLEIGQ
LSEPVKTQFGYHIIKITESRNAISFGTFQELMDSPEGNAYIQSKVEEYRKNDLIKNYVRAEEVPFPESVTVFQDQ

Sequences:

>Translated_315_residues
MRRHAQWLLLCLVIAILAGCGSEITTSQSKVLVEVGNSSITEAEFTTFLDLNSNIINQNASGLDANTTRQQLLDQMILQK
VILEESAKLGAGIDSVSAEQTTMMIDQAVGKEKPTYADYEAFAKENRFGTVESMRAYVAQILTYESYAQKLEVPSATPQF
HLFHILLSSDTVSESVALEQANQVLAQLKTGEDFSILAQQYSADPGSGSNGGDLGWYTQEQYAGFVPEFAAALNTLEIGQ
LSEPVKTQFGYHIIKITESRNAISFGTFQELMDSPEGNAYIQSKVEEYRKNDLIKNYVRAEEVPFPESVTVFQDQ
>Mature_315_residues
MRRHAQWLLLCLVIAILAGCGSEITTSQSKVLVEVGNSSITEAEFTTFLDLNSNIINQNASGLDANTTRQQLLDQMILQK
VILEESAKLGAGIDSVSAEQTTMMIDQAVGKEKPTYADYEAFAKENRFGTVESMRAYVAQILTYESYAQKLEVPSATPQF
HLFHILLSSDTVSESVALEQANQVLAQLKTGEDFSILAQQYSADPGSGSNGGDLGWYTQEQYAGFVPEFAAALNTLEIGQ
LSEPVKTQFGYHIIKITESRNAISFGTFQELMDSPEGNAYIQSKVEEYRKNDLIKNYVRAEEVPFPESVTVFQDQ

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=105, Percent_Identity=40, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 34800; Mature: 34800

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRHAQWLLLCLVIAILAGCGSEITTSQSKVLVEVGNSSITEAEFTTFLDLNSNIINQNA
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHEEEECCCHHHCCCC
SGLDANTTRQQLLDQMILQKVILEESAKLGAGIDSVSAEQTTMMIDQAVGKEKPTYADYE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHH
AFAKENRFGTVESMRAYVAQILTYESYAQKLEVPSATPQFHLFHILLSSDTVSESVALEQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHH
ANQVLAQLKTGEDFSILAQQYSADPGSGSNGGDLGWYTQEQYAGFVPEFAAALNTLEIGQ
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHH
LSEPVKTQFGYHIIKITESRNAISFGTFQELMDSPEGNAYIQSKVEEYRKNDLIKNYVRA
CCCHHHHHCCEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EEVPFPESVTVFQDQ
HCCCCCCCEECEECC
>Mature Secondary Structure
MRRHAQWLLLCLVIAILAGCGSEITTSQSKVLVEVGNSSITEAEFTTFLDLNSNIINQNA
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHEEEECCCHHHCCCC
SGLDANTTRQQLLDQMILQKVILEESAKLGAGIDSVSAEQTTMMIDQAVGKEKPTYADYE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHH
AFAKENRFGTVESMRAYVAQILTYESYAQKLEVPSATPQFHLFHILLSSDTVSESVALEQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHH
ANQVLAQLKTGEDFSILAQQYSADPGSGSNGGDLGWYTQEQYAGFVPEFAAALNTLEIGQ
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHH
LSEPVKTQFGYHIIKITESRNAISFGTFQELMDSPEGNAYIQSKVEEYRKNDLIKNYVRA
CCCHHHHHCCEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EEVPFPESVTVFQDQ
HCCCCCCCEECEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA