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The map label for this gene is frzF [H]

Identifier: 159897257

GI number: 159897257

Start: 836835

End: 838295

Strand: Direct

Name: frzF [H]

Synonym: Haur_0728

Alternate gene names: 159897257

Gene position: 836835-838295 (Clockwise)

Preceding gene: 159897256

Following gene: 159897258

Centisome position: 13.19

GC content: 53.59

Gene sequence:

>1461_bases
ATGAGCGAGTTGAGCACTGAACAATGGATGATCATCCGCGATTATCTGGCTCAACGGGCTGGCTTATATCTCGATGATAG
TCGTATGCGCCAAGGTCGTATGCTTGTTCAGGAGCGTTATCGGCAATTACAAATTAGCCCCGCTGCCTATACATTGCGAA
TTCAAGACCCCACTAATGGCGGCGAGTTGCAATGGTTGGCTGAACGCTTAGCTAACCATGAAACCCAATTTTTTCGCAAC
CCAGCCCATTTTCGAGCGTTGCGTGAGCATATTCTGCCTGAATTGCAGCGTTCGCGTTCGCCCTTGCGACCATTACGCTG
TTGGAGTGCTGGCTGCTCAACTGGCGAGGAACCCTATAGCATGGCCATGGTGGCCTTGCAGCAATGGGGCAATCCGCCGA
GCCGCCCAATTTCGATTTGGGCCACCGATTTGAGCAATGTGCCCTTGGAGCGAGCGATTGCCGCCGAGTATCGTGGCCGT
TCGCTAACAAATGTGCAAGCCGACTACAGACAATGGTTTGAGCAGCAGGCCAACGGAGCGTTGCGTGTCAGCGAAGCCGT
GCGATCCTTGGTACAATTTGAGCAGCACAATTTGCTGGATGCCCTGCCACATTGGGCCTATCAACTTGATGTGGTATTTT
GCCAGAATGTCACGATCTATTTTCAGCTGGAAACATGTCGCCAATTGATCGAACGGATTTATGCGGCGATGGCGGTTGGT
GGCTATCTGCTCTTGGGCTTTTCCGAGTCGCTGTGGGGCATTTTTGATCGCTTTGAAACGGTCGAGGTGGCTGGGGCATT
CATCTATCGCAAAGGCGATGGTCAGCCTAAACCACGCCCCAACTTGAGCGAAGGACCAATCACCAAGCCGCTGAATAAGC
CAGCCGAGCCAGTACCAGCGCGGCCACGCCCAAGTACGCGGCCATTAGCGCCAGCCAGCCCAATTAAGCCGCCCGATGTG
ACGAGCTTGTTGGATGAAGCACGGAAATTGCGCGGCCAAGGCCAGCAGCGACGTGGATTAAGCCTGTTGGCGAGTATTGC
GCCCAACCAGCGCCAGCCAGCAATTTTGGCTTTAGCCGCGCAATTGCACGCCGATCTTGGGCAGCATGAGCAAGCGGCGG
CTGAGGCGCGGCGGGCATTAGAGCTTGATGTGCTGCAAGATGCTGCCTATGTCGTGCTGGGCATGATTGAACTCAATCAA
GGCGCATGGGATAAAGCGATTAATTATCTTGAGCGAGCCAGCTATTTAGTGCCCGATTCGCCAACGATTGCCTTTCATTT
AGCTGAAAGTTATCGCCATCAAGGGCGAGCAACCGCCGCCTTACGTTATTATCAACATGCCTTGCGCAAATTGGCGCAGC
ATTCAAGTAGTACGGTTATTGATGGAATTGCCGTGGGGTGGCTGCGTTCTGCTTGTGAACGCTGGATTGGCGGATTAGAA
GCCAGCCAAGGAACATTCTAA

Upstream 100 bases:

>100_bases
TGCCACGGGCGGCAGAGGAAGCTGGGGCTGCCATGGAATTTTTAGCTGCTGATCTGATTGCACCGCGTTTGGTGGCGTTG
CTCAGCGAAACTGAACGTCG

Downstream 100 bases:

>100_bases
AACTATGCAAAAAGCACAATCAGCAATCTATAGTTCACTGCTCAGTCACCGCGCCCAAGGTCGTGTGGCGGTTCTGCTTG
AGCCACCAGTACCAACCCCG

Product: TPR repeat-containing CheR-type MCP methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MSELSTEQWMIIRDYLAQRAGLYLDDSRMRQGRMLVQERYRQLQISPAAYTLRIQDPTNGGELQWLAERLANHETQFFRN
PAHFRALREHILPELQRSRSPLRPLRCWSAGCSTGEEPYSMAMVALQQWGNPPSRPISIWATDLSNVPLERAIAAEYRGR
SLTNVQADYRQWFEQQANGALRVSEAVRSLVQFEQHNLLDALPHWAYQLDVVFCQNVTIYFQLETCRQLIERIYAAMAVG
GYLLLGFSESLWGIFDRFETVEVAGAFIYRKGDGQPKPRPNLSEGPITKPLNKPAEPVPARPRPSTRPLAPASPIKPPDV
TSLLDEARKLRGQGQQRRGLSLLASIAPNQRQPAILALAAQLHADLGQHEQAAAEARRALELDVLQDAAYVVLGMIELNQ
GAWDKAINYLERASYLVPDSPTIAFHLAESYRHQGRATAALRYYQHALRKLAQHSSSTVIDGIAVGWLRSACERWIGGLE
ASQGTF

Sequences:

>Translated_486_residues
MSELSTEQWMIIRDYLAQRAGLYLDDSRMRQGRMLVQERYRQLQISPAAYTLRIQDPTNGGELQWLAERLANHETQFFRN
PAHFRALREHILPELQRSRSPLRPLRCWSAGCSTGEEPYSMAMVALQQWGNPPSRPISIWATDLSNVPLERAIAAEYRGR
SLTNVQADYRQWFEQQANGALRVSEAVRSLVQFEQHNLLDALPHWAYQLDVVFCQNVTIYFQLETCRQLIERIYAAMAVG
GYLLLGFSESLWGIFDRFETVEVAGAFIYRKGDGQPKPRPNLSEGPITKPLNKPAEPVPARPRPSTRPLAPASPIKPPDV
TSLLDEARKLRGQGQQRRGLSLLASIAPNQRQPAILALAAQLHADLGQHEQAAAEARRALELDVLQDAAYVVLGMIELNQ
GAWDKAINYLERASYLVPDSPTIAFHLAESYRHQGRATAALRYYQHALRKLAQHSSSTVIDGIAVGWLRSACERWIGGLE
ASQGTF
>Mature_485_residues
SELSTEQWMIIRDYLAQRAGLYLDDSRMRQGRMLVQERYRQLQISPAAYTLRIQDPTNGGELQWLAERLANHETQFFRNP
AHFRALREHILPELQRSRSPLRPLRCWSAGCSTGEEPYSMAMVALQQWGNPPSRPISIWATDLSNVPLERAIAAEYRGRS
LTNVQADYRQWFEQQANGALRVSEAVRSLVQFEQHNLLDALPHWAYQLDVVFCQNVTIYFQLETCRQLIERIYAAMAVGG
YLLLGFSESLWGIFDRFETVEVAGAFIYRKGDGQPKPRPNLSEGPITKPLNKPAEPVPARPRPSTRPLAPASPIKPPDVT
SLLDEARKLRGQGQQRRGLSLLASIAPNQRQPAILALAAQLHADLGQHEQAAAEARRALELDVLQDAAYVVLGMIELNQG
AWDKAINYLERASYLVPDSPTIAFHLAESYRHQGRATAALRYYQHALRKLAQHSSSTVIDGIAVGWLRSACERWIGGLEA
SQGTF

Specific function: This methyltransferase is one of the proteins required for the normal aggregation of M.xanthus cells during fruiting body formation. It is also a component of a sensory transduction pathway that controls the frequency at which cells reverse their gliding

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1788193, Length=260, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01739 CheR; PF03705 CheR_N [H]

EC number: =2.1.1.80 [H]

Molecular weight: Translated: 54798; Mature: 54667

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION ; PS50123 CHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELSTEQWMIIRDYLAQRAGLYLDDSRMRQGRMLVQERYRQLQISPAAYTLRIQDPTNG
CCCCCCHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCC
GELQWLAERLANHETQFFRNPAHFRALREHILPELQRSRSPLRPLRCWSAGCSTGEEPYS
CHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHH
MAMVALQQWGNPPSRPISIWATDLSNVPLERAIAAEYRGRSLTNVQADYRQWFEQQANGA
HHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
LRVSEAVRSLVQFEQHNLLDALPHWAYQLDVVFCQNVTIYFQLETCRQLIERIYAAMAVG
CHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEECCEEEEEEHHHHHHHHHHHHHHHHHH
GYLLLGFSESLWGIFDRFETVEVAGAFIYRKGDGQPKPRPNLSEGPITKPLNKPAEPVPA
HHHEEECCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPRPSTRPLAPASPIKPPDVTSLLDEARKLRGQGQQRRGLSLLASIAPNQRQPAILALAA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
QLHADLGQHEQAAAEARRALELDVLQDAAYVVLGMIELNQGAWDKAINYLERASYLVPDS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
PTIAFHLAESYRHQGRATAALRYYQHALRKLAQHSSSTVIDGIAVGWLRSACERWIGGLE
CCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
ASQGTF
CCCCCC
>Mature Secondary Structure 
SELSTEQWMIIRDYLAQRAGLYLDDSRMRQGRMLVQERYRQLQISPAAYTLRIQDPTNG
CCCCCHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCC
GELQWLAERLANHETQFFRNPAHFRALREHILPELQRSRSPLRPLRCWSAGCSTGEEPYS
CHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHH
MAMVALQQWGNPPSRPISIWATDLSNVPLERAIAAEYRGRSLTNVQADYRQWFEQQANGA
HHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
LRVSEAVRSLVQFEQHNLLDALPHWAYQLDVVFCQNVTIYFQLETCRQLIERIYAAMAVG
CHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEECCEEEEEEHHHHHHHHHHHHHHHHHH
GYLLLGFSESLWGIFDRFETVEVAGAFIYRKGDGQPKPRPNLSEGPITKPLNKPAEPVPA
HHHEEECCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPRPSTRPLAPASPIKPPDVTSLLDEARKLRGQGQQRRGLSLLASIAPNQRQPAILALAA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
QLHADLGQHEQAAAEARRALELDVLQDAAYVVLGMIELNQGAWDKAINYLERASYLVPDS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
PTIAFHLAESYRHQGRATAALRYYQHALRKLAQHSSSTVIDGIAVGWLRSACERWIGGLE
CCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
ASQGTF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2168368 [H]