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The map label for this gene is rsbU [H]

Identifier: 159897258

GI number: 159897258

Start: 838300

End: 839394

Strand: Direct

Name: rsbU [H]

Synonym: Haur_0729

Alternate gene names: 159897258

Gene position: 838300-839394 (Clockwise)

Preceding gene: 159897257

Following gene: 159897259

Centisome position: 13.21

GC content: 52.88

Gene sequence:

>1095_bases
ATGCAAAAAGCACAATCAGCAATCTATAGTTCACTGCTCAGTCACCGCGCCCAAGGTCGTGTGGCGGTTCTGCTTGAGCC
ACCAGTACCAACCCCGCCCGTAGCGCCTGAACCCGACCAACGCCAAGCTGAACTGGAACAAGATTTGCAATTGGCGCGAG
ATTTGCAACAGGGCTTGATGCTCGAAACCGTGCCGCGCCTGCCTGGCTGGGAAATGAGCGCGGTCTCATTGCCAGCGCGT
GAGCTTGGCGGCGACCTCTATGATTTTTTGGCGGTCAACGGCTCGCAGGGAATTATGATTGGCGATGTGAGCGGCAAGGG
CTTACCTGCGGCGTTGCGGATGGCGGTAGCACGAACCGTGTTTCGGGCTGAAGTCCGGCGCGGCCAATCGCCAGGCCAAA
CCCTAGCGGCAGTCAATAATATTTTGATCGAAGAAATGCCCCAAGGCATGGTTACGATGCTCTATGCCTTAATCGACCCG
CAAACGGGCATGATGCACTTGGCGAATGCTGGTCACAATTATCTGATTGTGATCAATAATCAAGTGATTGAAATCGAAAC
GTCAGGTGTGCCACTTGGGGTTATGGAAATTGATTGTTATAGTGAATCCATCTTACAACTGAACTATGGCGATTCAGTCA
TGTTGTACACTGATGGTATTGTTGAAGCGACCAACGAACACCAAGTATTGTATGGCTACCCGCGTTTTCAAAGCCTGTTA
CAAGCAGTTGGCCATCTCAAGCCTCGCGCCTTGATGGCCCGCGTGCTGAGCGAAGTTCGCGCATGGACCCAAGGCCAGCT
TAAACACGATGATGTGACGATGGTGCTAGTCCGGCGGCGCTTGGCCAATTTGCTTGATGAAATGCATAGCATTGTGGCCG
ATGTGGTTGGGCCAATCACTGCTGACGAGTGGTGGCAAGCCTTGAGCTTGGTTGGTACAACCCGCACACCCGACCAATGT
TTAGAGTTATTGCGCCCGCTGAATGAAATGGTATCCAGCCAATTTGGCCGTGGGATTGCCCGCGAACTCCAAGCGCAATT
GCGCCCAGTGATCGAAGAATATCGCTTGCTCCAATCCACCAAAGGATCGTCCTAA

Upstream 100 bases:

>100_bases
AGTAGTACGGTTATTGATGGAATTGCCGTGGGGTGGCTGCGTTCTGCTTGTGAACGCTGGATTGGCGGATTAGAAGCCAG
CCAAGGAACATTCTAAAACT

Downstream 100 bases:

>100_bases
GGGAACTGTTATGACTACCAATGTTGACACTTTGAATGTAATGCCGCTGGACCTCGATACCTTTGCTGGGAGCGAGCGTT
TTATGGCTGGGACGCGCTTG

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MQKAQSAIYSSLLSHRAQGRVAVLLEPPVPTPPVAPEPDQRQAELEQDLQLARDLQQGLMLETVPRLPGWEMSAVSLPAR
ELGGDLYDFLAVNGSQGIMIGDVSGKGLPAALRMAVARTVFRAEVRRGQSPGQTLAAVNNILIEEMPQGMVTMLYALIDP
QTGMMHLANAGHNYLIVINNQVIEIETSGVPLGVMEIDCYSESILQLNYGDSVMLYTDGIVEATNEHQVLYGYPRFQSLL
QAVGHLKPRALMARVLSEVRAWTQGQLKHDDVTMVLVRRRLANLLDEMHSIVADVVGPITADEWWQALSLVGTTRTPDQC
LELLRPLNEMVSSQFGRGIARELQAQLRPVIEEYRLLQSTKGSS

Sequences:

>Translated_364_residues
MQKAQSAIYSSLLSHRAQGRVAVLLEPPVPTPPVAPEPDQRQAELEQDLQLARDLQQGLMLETVPRLPGWEMSAVSLPAR
ELGGDLYDFLAVNGSQGIMIGDVSGKGLPAALRMAVARTVFRAEVRRGQSPGQTLAAVNNILIEEMPQGMVTMLYALIDP
QTGMMHLANAGHNYLIVINNQVIEIETSGVPLGVMEIDCYSESILQLNYGDSVMLYTDGIVEATNEHQVLYGYPRFQSLL
QAVGHLKPRALMARVLSEVRAWTQGQLKHDDVTMVLVRRRLANLLDEMHSIVADVVGPITADEWWQALSLVGTTRTPDQC
LELLRPLNEMVSSQFGRGIARELQAQLRPVIEEYRLLQSTKGSS
>Mature_364_residues
MQKAQSAIYSSLLSHRAQGRVAVLLEPPVPTPPVAPEPDQRQAELEQDLQLARDLQQGLMLETVPRLPGWEMSAVSLPAR
ELGGDLYDFLAVNGSQGIMIGDVSGKGLPAALRMAVARTVFRAEVRRGQSPGQTLAAVNNILIEEMPQGMVTMLYALIDP
QTGMMHLANAGHNYLIVINNQVIEIETSGVPLGVMEIDCYSESILQLNYGDSVMLYTDGIVEATNEHQVLYGYPRFQSLL
QAVGHLKPRALMARVLSEVRAWTQGQLKHDDVTMVLVRRRLANLLDEMHSIVADVVGPITADEWWQALSLVGTTRTPDQC
LELLRPLNEMVSSQFGRGIARELQAQLRPVIEEYRLLQSTKGSS

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 40138; Mature: 40138

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKAQSAIYSSLLSHRAQGRVAVLLEPPVPTPPVAPEPDQRQAELEQDLQLARDLQQGLM
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCH
LETVPRLPGWEMSAVSLPARELGGDLYDFLAVNGSQGIMIGDVSGKGLPAALRMAVARTV
HHHCCCCCCCCCHHHCCCHHHHCCHHHHHHEECCCCCEEEECCCCCCCHHHHHHHHHHHH
FRAEVRRGQSPGQTLAAVNNILIEEMPQGMVTMLYALIDPQTGMMHLANAGHNYLIVINN
HHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECC
QVIEIETSGVPLGVMEIDCYSESILQLNYGDSVMLYTDGIVEATNEHQVLYGYPRFQSLL
EEEEEEECCCCEEEEEECCCCCCEEEEECCCEEEEEECCCEECCCCCEEEECCHHHHHHH
QAVGHLKPRALMARVLSEVRAWTQGQLKHDDVTMVLVRRRLANLLDEMHSIVADVVGPIT
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ADEWWQALSLVGTTRTPDQCLELLRPLNEMVSSQFGRGIARELQAQLRPVIEEYRLLQST
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
KGSS
CCCC
>Mature Secondary Structure
MQKAQSAIYSSLLSHRAQGRVAVLLEPPVPTPPVAPEPDQRQAELEQDLQLARDLQQGLM
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCH
LETVPRLPGWEMSAVSLPARELGGDLYDFLAVNGSQGIMIGDVSGKGLPAALRMAVARTV
HHHCCCCCCCCCHHHCCCHHHHCCHHHHHHEECCCCCEEEECCCCCCCHHHHHHHHHHHH
FRAEVRRGQSPGQTLAAVNNILIEEMPQGMVTMLYALIDPQTGMMHLANAGHNYLIVINN
HHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECC
QVIEIETSGVPLGVMEIDCYSESILQLNYGDSVMLYTDGIVEATNEHQVLYGYPRFQSLL
EEEEEEECCCCEEEEEECCCCCCEEEEECCCEEEEEECCCEECCCCCEEEECCHHHHHHH
QAVGHLKPRALMARVLSEVRAWTQGQLKHDDVTMVLVRRRLANLLDEMHSIVADVVGPIT
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ADEWWQALSLVGTTRTPDQCLELLRPLNEMVSSQFGRGIARELQAQLRPVIEEYRLLQST
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
KGSS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]