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The map label for this gene is mtrA [H]

Identifier: 159897249

GI number: 159897249

Start: 829203

End: 829913

Strand: Direct

Name: mtrA [H]

Synonym: Haur_0720

Alternate gene names: 159897249

Gene position: 829203-829913 (Clockwise)

Preceding gene: 159897248

Following gene: 159897250

Centisome position: 13.07

GC content: 51.9

Gene sequence:

>711_bases
ATGCCAGCACGATGGCGTATTCTTGTAGTTGATGATGACACGATTATTCGCCGCACGCTCGTGAGCAATTTGCTTAACGA
TGGGTTTGAAGTAATGGCGGCAGAATCAGGCCAATCGGCCTTGACCATGGTCGAAAGTTCATGGCCTGATCTGGCGATTC
TCGATTTGATGATGCCTGGTATGACTGGCTTTGAACTATCCGACCGTTTGCGGCGCTATGTGGAAATTCCGGTAATTATG
CTGACCTCGATTTCTGATGAGGCTACGACCGTGCGCGGCCTTGAGCAGCATGCCGATGATTATATGACTAAGCCCTATCG
CTACCCTGAATTGCGAGCGCGGGTCAACAAACTGCTGACCAAATCGTATGAAGGTGGCTTGCATCCAGGCGAGTTGGTGG
TGATTGACGAAGATCTTTCGGTCAATTTTGGTCAGCATATTCTGTTGCGCAAGGGCGAGGCCATTCCGTTGGAGCCGATT
GAGCTACGAGTGTTGTATTTGCTGCTCCAAACGCCAACCGTGGCGGTGGCAACCACAACCCTGTTACGTAAAGCGTGGGG
TTTGGGCGAAGAGGGCGATCAATCCTCGTTGTGGGTGCGAATTCGCTCGTTGCGCACCAAACTTGAGGACAATCCATCGA
AGCCGATCTACTTAAAAACTGTGCGTGGCGTGGGCTACGTGTTTGACGTACAACCACGGCGCGGCTTGTAA

Upstream 100 bases:

>100_bases
TTTAGCAGTTGGTGCTCATGGCGGCACAATTAGCGTGGATAGCCAAGTAGGCAAGGGGACGACGGTCACCGTGCAACTAC
CTTGGAAGGAGTAAACTCTA

Downstream 100 bases:

>100_bases
TCTTACTCGTAAACTTACATTCTTATAGTGGTGGTGATGGTTGCCCAAATGATCCATCGCTATAAGGATGTTAAGTATGC
TAAAGACTGTTTTGCTGGTT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MPARWRILVVDDDTIIRRTLVSNLLNDGFEVMAAESGQSALTMVESSWPDLAILDLMMPGMTGFELSDRLRRYVEIPVIM
LTSISDEATTVRGLEQHADDYMTKPYRYPELRARVNKLLTKSYEGGLHPGELVVIDEDLSVNFGQHILLRKGEAIPLEPI
ELRVLYLLLQTPTVAVATTTLLRKAWGLGEEGDQSSLWVRIRSLRTKLEDNPSKPIYLKTVRGVGYVFDVQPRRGL

Sequences:

>Translated_236_residues
MPARWRILVVDDDTIIRRTLVSNLLNDGFEVMAAESGQSALTMVESSWPDLAILDLMMPGMTGFELSDRLRRYVEIPVIM
LTSISDEATTVRGLEQHADDYMTKPYRYPELRARVNKLLTKSYEGGLHPGELVVIDEDLSVNFGQHILLRKGEAIPLEPI
ELRVLYLLLQTPTVAVATTTLLRKAWGLGEEGDQSSLWVRIRSLRTKLEDNPSKPIYLKTVRGVGYVFDVQPRRGL
>Mature_235_residues
PARWRILVVDDDTIIRRTLVSNLLNDGFEVMAAESGQSALTMVESSWPDLAILDLMMPGMTGFELSDRLRRYVEIPVIML
TSISDEATTVRGLEQHADDYMTKPYRYPELRARVNKLLTKSYEGGLHPGELVVIDEDLSVNFGQHILLRKGEAIPLEPIE
LRVLYLLLQTPTVAVATTTLLRKAWGLGEEGDQSSLWVRIRSLRTKLEDNPSKPIYLKTVRGVGYVFDVQPRRGL

Specific function: Member of the two-component regulatory system mtrA/mtrB [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=34.2342342342342, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=34.061135371179, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=33.1896551724138, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=30.3030303030303, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=30.0448430493274, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=30.3030303030303, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=28.5087719298246, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=29.0178571428571, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=30.3964757709251, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=32.15859030837, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=28.1938325991189, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=31.4159292035398, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=29.646017699115, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=35, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=26.9565217391304, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=34.453781512605, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26694; Mature: 26563

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARWRILVVDDDTIIRRTLVSNLLNDGFEVMAAESGQSALTMVESSWPDLAILDLMMPG
CCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHCCC
MTGFELSDRLRRYVEIPVIMLTSISDEATTVRGLEQHADDYMTKPYRYPELRARVNKLLT
CCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KSYEGGLHPGELVVIDEDLSVNFGQHILLRKGEAIPLEPIELRVLYLLLQTPTVAVATTT
HHCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
LLRKAWGLGEEGDQSSLWVRIRSLRTKLEDNPSKPIYLKTVRGVGYVFDVQPRRGL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCCCC
>Mature Secondary Structure 
PARWRILVVDDDTIIRRTLVSNLLNDGFEVMAAESGQSALTMVESSWPDLAILDLMMPG
CCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHCCC
MTGFELSDRLRRYVEIPVIMLTSISDEATTVRGLEQHADDYMTKPYRYPELRARVNKLLT
CCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KSYEGGLHPGELVVIDEDLSVNFGQHILLRKGEAIPLEPIELRVLYLLLQTPTVAVATTT
HHCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
LLRKAWGLGEEGDQSSLWVRIRSLRTKLEDNPSKPIYLKTVRGVGYVFDVQPRRGL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]