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The map label for this gene is resE [H]

Identifier: 159897248

GI number: 159897248

Start: 827601

End: 829196

Strand: Direct

Name: resE [H]

Synonym: Haur_0719

Alternate gene names: 159897248

Gene position: 827601-829196 (Clockwise)

Preceding gene: 159897247

Following gene: 159897249

Centisome position: 13.04

GC content: 50.56

Gene sequence:

>1596_bases
ATGCAAGCAACACCCGAACTAATTTTGATTGTGGATGATCAAACCACCAATGTGATGGTGTTACAGCGGATGTTAGAACG
CGCTGGTTATGCTACTGCCTGTGCTCGCAGCGGCTTCGAAGCCTTGACCATGCTCGAACAACAAGTTCCCGATTTGATTT
TGCTTGACGTAATGATGCCGGAGATGGATGGCTATCAAACGCTTCAGGCGATTCGTGAACGTAATCATCTGCCATTTATT
CCAATTATCTTTGTTTCGGCCAAGCAAACCACCGCCGATACGGTAACTGGTTTGGATTTGGGCGCTGATGATTACGTTAC
CAAGCCCGTCAATCGTGATGAATTGCTGGCTCGTATGCGGGTGCTGTTGCGTTTGAAGCATACGCGACGGGCGCTCCATC
GTGAACAAGAACGTTTGCGCTTTCTCTATCGGGTTTCGCAAACCTTGCATCGCTCGTTGGATATTGATCAAGTGCTGCCC
GAAGCCTTGAATGCGATCAACGAGCTGTTGGGAGCCAGCCGTGGTAGCGTCTTGCTACTTGATGATCAAAATCGGGTTTG
GCGGCGAATTCTGTTTCGACCGCATTTGCCGCCTGCCGAGGCTGAACAAGCGATTCAGGCGGTGTTGCGTGAAGGTTTGG
CCTCGTATGCCTTGCGCACTGGCGAAGTCCAAATCGTCGAAGATGCCCAAAACGATCCCCGCTGGAAGCATTTTTATGAT
GATCGCGAGGAAATTGGCTCGGCGCTGGCCTTGCCATTGCATAATTATGCCCAAAATACGATTATCGGCGTATTTATCTT
GGTGCATCCCCAACGCAACTTCTTCCGCACCGAGCTAGAAACCCTGATCAAAGCCTTGACTGATCAATTAAGCGTGGCCT
TGACCAATGCGGCGGTTTACACTCGTTTGCGCGAAGCTGAAGATAGCCGCGATAGTTTTATTCAGATGCTGACCCATGAC
TTACGCGCACCTTTGGCGGGCATGGTTGGCTGCTTCGATGCCTTGATGACCACCCAACTTGACGATGATGGCAAATTGTT
TGTCGAGCTTGGCTTTCGAGCCGGAGCTGCCCAACAACGCCTGATCGACGATTTGCTTGATGTTTACAAGGCTGAGGCAG
GCCGCTTGATGCTTAGCAAGGAAACCACCAGCTTGCAACGTTTGGGTGAATTGCTGAGCGAGCAAGTATTGGGAATTACG
GTTGAACAACAACTGAGCTTTGAGCTTGATCTGCCAGCCGAGCCATTGGTGGTGCTTGATGAGCATAAAATGGTGCGCGT
ATTGGCCAATCTGGTCAGCAACGGCATCAAATGGACAAGGCCAGGTGGTACAATTCGCGTGGTTGGAACGATTGATCAAG
CGCAGCAACTGATTACCCTAAACGTCAGCGATACGGGGCAGGGGATTGCTGCCGAAGATATTCCACATATTTTCGATAAA
TTTTATCAAGGTCGTACTACCGCCCAATCGCGGGGCACTGGTTTAGGCTTGACCTTTTGTAATTTAGCAGTTGGTGCTCA
TGGCGGCACAATTAGCGTGGATAGCCAAGTAGGCAAGGGGACGACGGTCACCGTGCAACTACCTTGGAAGGAGTAA

Upstream 100 bases:

>100_bases
GCAGGTCAGCCAAACCCTAGAACAAAGCTACGAACGCTGGATGGAACTTTCTGAGCTAGCGTCGGCTTCGTAATTTTCAG
CGCATGGATGGAGCACAGGA

Downstream 100 bases:

>100_bases
ACTCTAATGCCAGCACGATGGCGTATTCTTGTAGTTGATGATGACACGATTATTCGCCGCACGCTCGTGAGCAATTTGCT
TAACGATGGGTTTGAAGTAA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MQATPELILIVDDQTTNVMVLQRMLERAGYATACARSGFEALTMLEQQVPDLILLDVMMPEMDGYQTLQAIRERNHLPFI
PIIFVSAKQTTADTVTGLDLGADDYVTKPVNRDELLARMRVLLRLKHTRRALHREQERLRFLYRVSQTLHRSLDIDQVLP
EALNAINELLGASRGSVLLLDDQNRVWRRILFRPHLPPAEAEQAIQAVLREGLASYALRTGEVQIVEDAQNDPRWKHFYD
DREEIGSALALPLHNYAQNTIIGVFILVHPQRNFFRTELETLIKALTDQLSVALTNAAVYTRLREAEDSRDSFIQMLTHD
LRAPLAGMVGCFDALMTTQLDDDGKLFVELGFRAGAAQQRLIDDLLDVYKAEAGRLMLSKETTSLQRLGELLSEQVLGIT
VEQQLSFELDLPAEPLVVLDEHKMVRVLANLVSNGIKWTRPGGTIRVVGTIDQAQQLITLNVSDTGQGIAAEDIPHIFDK
FYQGRTTAQSRGTGLGLTFCNLAVGAHGGTISVDSQVGKGTTVTVQLPWKE

Sequences:

>Translated_531_residues
MQATPELILIVDDQTTNVMVLQRMLERAGYATACARSGFEALTMLEQQVPDLILLDVMMPEMDGYQTLQAIRERNHLPFI
PIIFVSAKQTTADTVTGLDLGADDYVTKPVNRDELLARMRVLLRLKHTRRALHREQERLRFLYRVSQTLHRSLDIDQVLP
EALNAINELLGASRGSVLLLDDQNRVWRRILFRPHLPPAEAEQAIQAVLREGLASYALRTGEVQIVEDAQNDPRWKHFYD
DREEIGSALALPLHNYAQNTIIGVFILVHPQRNFFRTELETLIKALTDQLSVALTNAAVYTRLREAEDSRDSFIQMLTHD
LRAPLAGMVGCFDALMTTQLDDDGKLFVELGFRAGAAQQRLIDDLLDVYKAEAGRLMLSKETTSLQRLGELLSEQVLGIT
VEQQLSFELDLPAEPLVVLDEHKMVRVLANLVSNGIKWTRPGGTIRVVGTIDQAQQLITLNVSDTGQGIAAEDIPHIFDK
FYQGRTTAQSRGTGLGLTFCNLAVGAHGGTISVDSQVGKGTTVTVQLPWKE
>Mature_531_residues
MQATPELILIVDDQTTNVMVLQRMLERAGYATACARSGFEALTMLEQQVPDLILLDVMMPEMDGYQTLQAIRERNHLPFI
PIIFVSAKQTTADTVTGLDLGADDYVTKPVNRDELLARMRVLLRLKHTRRALHREQERLRFLYRVSQTLHRSLDIDQVLP
EALNAINELLGASRGSVLLLDDQNRVWRRILFRPHLPPAEAEQAIQAVLREGLASYALRTGEVQIVEDAQNDPRWKHFYD
DREEIGSALALPLHNYAQNTIIGVFILVHPQRNFFRTELETLIKALTDQLSVALTNAAVYTRLREAEDSRDSFIQMLTHD
LRAPLAGMVGCFDALMTTQLDDDGKLFVELGFRAGAAQQRLIDDLLDVYKAEAGRLMLSKETTSLQRLGELLSEQVLGIT
VEQQLSFELDLPAEPLVVLDEHKMVRVLANLVSNGIKWTRPGGTIRVVGTIDQAQQLITLNVSDTGQGIAAEDIPHIFDK
FYQGRTTAQSRGTGLGLTFCNLAVGAHGGTISVDSQVGKGTTVTVQLPWKE

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=228, Percent_Identity=31.140350877193, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788713, Length=257, Percent_Identity=26.8482490272374, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=28.755364806867, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=29.6943231441048, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1790437, Length=121, Percent_Identity=40.495867768595, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=31.2236286919831, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87082012, Length=122, Percent_Identity=40.1639344262295, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788394, Length=134, Percent_Identity=38.8059701492537, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=25.8771929824561, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790860, Length=119, Percent_Identity=34.453781512605, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787229, Length=139, Percent_Identity=35.9712230215827, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=35.042735042735, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=37.6068376068376, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI2367329, Length=120, Percent_Identity=43.3333333333333, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=29.7777777777778, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=26.2931034482759, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=36.7521367521368, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=130, Percent_Identity=36.9230769230769, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790552, Length=117, Percent_Identity=37.6068376068376, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=35.1351351351351, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=270, Percent_Identity=26.2962962962963, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787375, Length=117, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786911, Length=121, Percent_Identity=36.3636363636364, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790863, Length=120, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=26.0504201680672, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787487, Length=103, Percent_Identity=35.9223300970874, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788905, Length=115, Percent_Identity=33.9130434782609, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=223, Percent_Identity=24.6636771300448, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59333; Mature: 59333

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQATPELILIVDDQTTNVMVLQRMLERAGYATACARSGFEALTMLEQQVPDLILLDVMMP
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCCEEEHHHHCC
EMDGYQTLQAIRERNHLPFIPIIFVSAKQTTADTVTGLDLGADDYVTKPVNRDELLARMR
CCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHH
VLLRLKHTRRALHREQERLRFLYRVSQTLHRSLDIDQVLPEALNAINELLGASRGSVLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
DDQNRVWRRILFRPHLPPAEAEQAIQAVLREGLASYALRTGEVQIVEDAQNDPRWKHFYD
ECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHCC
DREEIGSALALPLHNYAQNTIIGVFILVHPQRNFFRTELETLIKALTDQLSVALTNAAVY
CHHHHCHHHHHHHHHHHHHCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLREAEDSRDSFIQMLTHDLRAPLAGMVGCFDALMTTQLDDDGKLFVELGFRAGAAQQR
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHH
LIDDLLDVYKAEAGRLMLSKETTSLQRLGELLSEQVLGITVEQQLSFELDLPAEPLVVLD
HHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCEEEECCEEEEECCCCCCEEEEC
EHKMVRVLANLVSNGIKWTRPGGTIRVVGTIDQAQQLITLNVSDTGQGIAAEDIPHIFDK
CHHHHHHHHHHHHCCCEEECCCCEEEEEEEHHCCCEEEEEEECCCCCCCCHHHHHHHHHH
FYQGRTTAQSRGTGLGLTFCNLAVGAHGGTISVDSQVGKGTTVTVQLPWKE
HHCCCCCHHCCCCCCEEEHHHHHEECCCCEEEECCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MQATPELILIVDDQTTNVMVLQRMLERAGYATACARSGFEALTMLEQQVPDLILLDVMMP
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCCEEEHHHHCC
EMDGYQTLQAIRERNHLPFIPIIFVSAKQTTADTVTGLDLGADDYVTKPVNRDELLARMR
CCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHH
VLLRLKHTRRALHREQERLRFLYRVSQTLHRSLDIDQVLPEALNAINELLGASRGSVLLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
DDQNRVWRRILFRPHLPPAEAEQAIQAVLREGLASYALRTGEVQIVEDAQNDPRWKHFYD
ECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHCC
DREEIGSALALPLHNYAQNTIIGVFILVHPQRNFFRTELETLIKALTDQLSVALTNAAVY
CHHHHCHHHHHHHHHHHHHCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLREAEDSRDSFIQMLTHDLRAPLAGMVGCFDALMTTQLDDDGKLFVELGFRAGAAQQR
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHH
LIDDLLDVYKAEAGRLMLSKETTSLQRLGELLSEQVLGITVEQQLSFELDLPAEPLVVLD
HHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCEEEECCEEEEECCCCCCEEEEC
EHKMVRVLANLVSNGIKWTRPGGTIRVVGTIDQAQQLITLNVSDTGQGIAAEDIPHIFDK
CHHHHHHHHHHHHCCCEEECCCCEEEEEEEHHCCCEEEEEEECCCCCCCCHHHHHHHHHH
FYQGRTTAQSRGTGLGLTFCNLAVGAHGGTISVDSQVGKGTTVTVQLPWKE
HHCCCCCHHCCCCCCEEEHHHHHEECCCCEEEECCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]