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The map label for this gene is ygbD [C]

Identifier: 159897218

GI number: 159897218

Start: 792537

End: 793886

Strand: Direct

Name: ygbD [C]

Synonym: Haur_0689

Alternate gene names: 159897218

Gene position: 792537-793886 (Clockwise)

Preceding gene: 159897216

Following gene: 159897219

Centisome position: 12.49

GC content: 53.19

Gene sequence:

>1350_bases
ATGGCTAGCGAACGGGTGATCGTGATTGGAGCCGTCGCCGCCGGAACGAGTGCTGCCGCCAAAGCCAAACGCACCAATCC
CGATTTGGATATTTGTGTGTATGGCCGAGAAGCCCATGTTTCTTACTCTGCTTGTGGGTTGCCCTATTTGATTAGCGGGG
CAGTTGCTGATTATCAGGCGTTAATCGCCCGCACTCCAGCCCAATTTGCCCGCGATGGCGTGACCGTCAAAACCGAACAT
GAAGTGATTGATCTTGATGTAGCGGCGGGGCGGGTGACCGTGCGCGATTTGGCTACCAATAGTACGTTCCACGATCATTT
TGATCGTTTGGTGCTGGCAACTGGCGCGAGAGTCAATTGTCCACCAGTACGAGGGATTGAACTACAGGGGGTCTTTCGGT
TACGCTCAATGCATGATGGTTTGGCGATTCAAACCTACATCAGCGAACAGCAACCCAAGCATGCTGTCGTGGTTGGTGCT
GGCTATATTGGGCTAGAAATGGCCGAGGCCTTGCTCGATCGTGGGATTGGCGTAACCTTGGTCAATCGCAGCAAAACCGT
GTTAAGCTCACTCGATCACGATATGAGCAGCCAGATTATCTCCCGACTTGAAGCTGCGGGCGTGCAATTGGCGCTTGGTT
GTGGCTTGGAAGGCCTTGAAGGTAAGCACGATCGAGTGACCCATGTGGTCGCTGGAGGTCGCGATATTCCCGCCGAATTG
GTGATTATCGCGACTGGGGTACAGCCGAATAGCGAATTGGCGCAAAGCTGTGGTGCTGAGCTTGGCGAGCATGGCGCAAT
CAAAATCGACCAATTAGGCCGTACTAGCGTCGATAGGGTGTATGCCGCTGGCGATTGCAGTACCGTTGATCATCGAATTC
TCAATAAGCCCGTGTATTTACCACTGGGCACGACTGCCAATAAACAAGGGCGGACGCTTGGAGCCTATCTCGCAGGCCAC
GAACGCCCATTTCGCGGAGTTGTGGGCACAGCAGTCACCAAATTTGCTGATTTACATATTGCCGCAACTGGATTAAGTGT
TGAGCAAGCTCTCCACCATGGCTACCACGTTCGTAGCAAAATCATCCATTCAACCGATCATGCGGGGTACTACCCCAATG
CTCGGCCAATTACGGTTAAGTTGGTTGCCGACGCAGCTGACGGCACATTGTTGGGTGGCCAAATTATTGGCTTCGACGAT
GTAGCAAAGCGGGTTGATGTGGTAGCGGTGGCACTCGCGGGAAGAATGACGGTAGATGAGTTTGCTTGGCAAGACCTGAG
TTATGCACCCCCATTTTCATCGGTGTGGGACCCACTGTTGGTTGCTGCCCAAGCATTGGCTAAAGGCTAA

Upstream 100 bases:

>100_bases
TGGCAAACGTGGTTGATTCTTGCTAGGGCTTGGTGGCATAATTAAGGTCTCATGCTAGTGACAATCTGTCCAAATAGTAG
CATAGCTAAAGGAGCTTGGA

Downstream 100 bases:

>100_bases
GCTTGAAAGGACATTCTGTGAGCATCGAAACGCTTTTTGCCCATGCCCGTGCTGCCATAAGCACTGGCCGGAAGGAGGAG
GGGCGCAGCTTATTGATTTC

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MASERVIVIGAVAAGTSAAAKAKRTNPDLDICVYGREAHVSYSACGLPYLISGAVADYQALIARTPAQFARDGVTVKTEH
EVIDLDVAAGRVTVRDLATNSTFHDHFDRLVLATGARVNCPPVRGIELQGVFRLRSMHDGLAIQTYISEQQPKHAVVVGA
GYIGLEMAEALLDRGIGVTLVNRSKTVLSSLDHDMSSQIISRLEAAGVQLALGCGLEGLEGKHDRVTHVVAGGRDIPAEL
VIIATGVQPNSELAQSCGAELGEHGAIKIDQLGRTSVDRVYAAGDCSTVDHRILNKPVYLPLGTTANKQGRTLGAYLAGH
ERPFRGVVGTAVTKFADLHIAATGLSVEQALHHGYHVRSKIIHSTDHAGYYPNARPITVKLVADAADGTLLGGQIIGFDD
VAKRVDVVAVALAGRMTVDEFAWQDLSYAPPFSSVWDPLLVAAQALAKG

Sequences:

>Translated_449_residues
MASERVIVIGAVAAGTSAAAKAKRTNPDLDICVYGREAHVSYSACGLPYLISGAVADYQALIARTPAQFARDGVTVKTEH
EVIDLDVAAGRVTVRDLATNSTFHDHFDRLVLATGARVNCPPVRGIELQGVFRLRSMHDGLAIQTYISEQQPKHAVVVGA
GYIGLEMAEALLDRGIGVTLVNRSKTVLSSLDHDMSSQIISRLEAAGVQLALGCGLEGLEGKHDRVTHVVAGGRDIPAEL
VIIATGVQPNSELAQSCGAELGEHGAIKIDQLGRTSVDRVYAAGDCSTVDHRILNKPVYLPLGTTANKQGRTLGAYLAGH
ERPFRGVVGTAVTKFADLHIAATGLSVEQALHHGYHVRSKIIHSTDHAGYYPNARPITVKLVADAADGTLLGGQIIGFDD
VAKRVDVVAVALAGRMTVDEFAWQDLSYAPPFSSVWDPLLVAAQALAKG
>Mature_448_residues
ASERVIVIGAVAAGTSAAAKAKRTNPDLDICVYGREAHVSYSACGLPYLISGAVADYQALIARTPAQFARDGVTVKTEHE
VIDLDVAAGRVTVRDLATNSTFHDHFDRLVLATGARVNCPPVRGIELQGVFRLRSMHDGLAIQTYISEQQPKHAVVVGAG
YIGLEMAEALLDRGIGVTLVNRSKTVLSSLDHDMSSQIISRLEAAGVQLALGCGLEGLEGKHDRVTHVVAGGRDIPAELV
IIATGVQPNSELAQSCGAELGEHGAIKIDQLGRTSVDRVYAAGDCSTVDHRILNKPVYLPLGTTANKQGRTLGAYLAGHE
RPFRGVVGTAVTKFADLHIAATGLSVEQALHHGYHVRSKIIHSTDHAGYYPNARPITVKLVADAADGTLLGGQIIGFDDV
AKRVDVVAVALAGRMTVDEFAWQDLSYAPPFSSVWDPLLVAAQALAKG

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=324, Percent_Identity=24.6913580246914, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI65787454, Length=324, Percent_Identity=24.6913580246914, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI226437568, Length=324, Percent_Identity=24.6913580246914, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1789065, Length=326, Percent_Identity=28.2208588957055, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1789765, Length=378, Percent_Identity=24.6031746031746, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788892, Length=295, Percent_Identity=27.4576271186441, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082354, Length=138, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789915, Length=327, Percent_Identity=25.6880733944954, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786307, Length=306, Percent_Identity=24.8366013071895, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=244, Percent_Identity=27.4590163934426, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639257, Length=194, Percent_Identity=25.2577319587629, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281359715, Length=194, Percent_Identity=25.2577319587629, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281359713, Length=194, Percent_Identity=25.2577319587629, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639250, Length=194, Percent_Identity=25.2577319587629, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18543267, Length=194, Percent_Identity=25.2577319587629, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639252, Length=194, Percent_Identity=25.2577319587629, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585130, Length=253, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 47505; Mature: 47373

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASERVIVIGAVAAGTSAAAKAKRTNPDLDICVYGREAHVSYSACGLPYLISGAVADYQA
CCCCCEEEEEEEECCCHHHHHHHCCCCCEEEEEECCCCCCEEHHCCCCHHHHHHHHHHHH
LIARTPAQFARDGVTVKTEHEVIDLDVAAGRVTVRDLATNSTFHDHFDRLVLATGARVNC
HHHCCCHHHHHCCCEEEECCEEEEEEECCCEEEEEHHHCCCCHHHHHHHEEEECCCCCCC
PPVRGIELQGVFRLRSMHDGLAIQTYISEQQPKHAVVVGAGYIGLEMAEALLDRGIGVTL
CCCCCEEEHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEE
VNRSKTVLSSLDHDMSSQIISRLEAAGVQLALGCGLEGLEGKHDRVTHVVAGGRDIPAEL
ECCCHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCEE
VIIATGVQPNSELAQSCGAELGEHGAIKIDQLGRTSVDRVYAAGDCSTVDHRILNKPVYL
EEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHEEECCCCCHHHHHHHCCCEEE
PLGTTANKQGRTLGAYLAGHERPFRGVVGTAVTKFADLHIAATGLSVEQALHHGYHVRSK
EECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHEEEEEECCHHHHHHHCCHHHHHH
IIHSTDHAGYYPNARPITVKLVADAADGTLLGGQIIGFDDVAKRVDVVAVALAGRMTVDE
HHHCCCCCCCCCCCCCEEEEEEEECCCCEEECCEEECHHHHHHHHHHHEEEHHCCCCHHH
FAWQDLSYAPPFSSVWDPLLVAAQALAKG
HHHCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASERVIVIGAVAAGTSAAAKAKRTNPDLDICVYGREAHVSYSACGLPYLISGAVADYQA
CCCCEEEEEEEECCCHHHHHHHCCCCCEEEEEECCCCCCEEHHCCCCHHHHHHHHHHHH
LIARTPAQFARDGVTVKTEHEVIDLDVAAGRVTVRDLATNSTFHDHFDRLVLATGARVNC
HHHCCCHHHHHCCCEEEECCEEEEEEECCCEEEEEHHHCCCCHHHHHHHEEEECCCCCCC
PPVRGIELQGVFRLRSMHDGLAIQTYISEQQPKHAVVVGAGYIGLEMAEALLDRGIGVTL
CCCCCEEEHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEE
VNRSKTVLSSLDHDMSSQIISRLEAAGVQLALGCGLEGLEGKHDRVTHVVAGGRDIPAEL
ECCCHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCEE
VIIATGVQPNSELAQSCGAELGEHGAIKIDQLGRTSVDRVYAAGDCSTVDHRILNKPVYL
EEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHEEECCCCCHHHHHHHCCCEEE
PLGTTANKQGRTLGAYLAGHERPFRGVVGTAVTKFADLHIAATGLSVEQALHHGYHVRSK
EECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHEEEEEECCHHHHHHHCCHHHHHH
IIHSTDHAGYYPNARPITVKLVADAADGTLLGGQIIGFDDVAKRVDVVAVALAGRMTVDE
HHHCCCCCCCCCCCCCEEEEEEEECCCCEEECCEEECHHHHHHHHHHHEEEHHCCCCHHH
FAWQDLSYAPPFSSVWDPLLVAAQALAKG
HHHCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA