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The map label for this gene is resE [H]

Identifier: 159896980

GI number: 159896980

Start: 525327

End: 526139

Strand: Direct

Name: resE [H]

Synonym: Haur_0448

Alternate gene names: 159896980

Gene position: 525327-526139 (Clockwise)

Preceding gene: 159896979

Following gene: 159896981

Centisome position: 8.28

GC content: 51.29

Gene sequence:

>813_bases
ATGATTGTTCTACCGCTCAAATCGTTGCTTTTTGGAATTTTATTGCTACTGTGGCTGGTTGCCAGCTTTGCTTGGTGGCT
TGGTCAGCGTGGCAAACGCCCCATTATCCAACATAGCGCCGATCCATTATTGCGCCAACAAATTGCTCAGCATCGCGCCT
TTATTGGCACGCTTTCGCATGAATTACGCACACCATTAACCGCTCTTTTGGCGCATACCGCAATTGTGCACAACCAACAA
AGCGAGCCAGCCGTGCGCGAACATTCGTTGCTCACCTTGGAGCGTGAAGCTCAACGTATGGCTCGCTTGGTACGCGATTT
GTTGGAATTGCACCGTTTGGAATTAAGCGATGAATTGCCCTTGGTTCCGGTGAATGTGGCGTTGTTGGCCGAAGAAGCGA
TTGCCAGCGTGTGGGTGATGGCCGATGAAGCCCAAATTGAACTGCAATTCGAGGCTGACCCAACCCATCAGCGAGTTTTG
GCGCATCCTGATCGCTTAAAACAAGTCTGGCTCAATTTGTTGATGAATTGTTTGCGCTATTGTCGTGCAGGCGATCTGGT
GATTGTGCGGGTGCTGGCGAGTGAGCAAGGGTTACGTTGTAGCATTGAAGATAGTGGGCCTGGGATTGCTGCCACTGATT
TGCCGCATGTGACCGAGCCACTCTATCGCGGGGTCTTGGATAACGAAGGCAGCGGCTTGGGCTTGAGCCTAGTCAAACAG
ATTTTGGCGCGGCATCATAGCACCCTCCAGATTGAAAGTAGCACCAACCCGCCAACTGGCACACATATATGGTGGATCTT
GCCCTATGACTAA

Upstream 100 bases:

>100_bases
TGTGTGTGCAACGCTTACGTGCTAAAATCAACCAACTTGATGCGAATGCCGACCCGATTCAGACCGTGCGTGGTTTTGGC
TATCGGTTAAAGTGTGAGCC

Downstream 100 bases:

>100_bases
ATTGCGGTGGCTTAGCCTGCTCATTCTTGGTTCGATCATCTACTGGCTTTTGCCAATCGACGGCAATTTAGTGCTTCAGA
CCAACCAACAAGCTGGTTGG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MIVLPLKSLLFGILLLLWLVASFAWWLGQRGKRPIIQHSADPLLRQQIAQHRAFIGTLSHELRTPLTALLAHTAIVHNQQ
SEPAVREHSLLTLEREAQRMARLVRDLLELHRLELSDELPLVPVNVALLAEEAIASVWVMADEAQIELQFEADPTHQRVL
AHPDRLKQVWLNLLMNCLRYCRAGDLVIVRVLASEQGLRCSIEDSGPGIAATDLPHVTEPLYRGVLDNEGSGLGLSLVKQ
ILARHHSTLQIESSTNPPTGTHIWWILPYD

Sequences:

>Translated_270_residues
MIVLPLKSLLFGILLLLWLVASFAWWLGQRGKRPIIQHSADPLLRQQIAQHRAFIGTLSHELRTPLTALLAHTAIVHNQQ
SEPAVREHSLLTLEREAQRMARLVRDLLELHRLELSDELPLVPVNVALLAEEAIASVWVMADEAQIELQFEADPTHQRVL
AHPDRLKQVWLNLLMNCLRYCRAGDLVIVRVLASEQGLRCSIEDSGPGIAATDLPHVTEPLYRGVLDNEGSGLGLSLVKQ
ILARHHSTLQIESSTNPPTGTHIWWILPYD
>Mature_270_residues
MIVLPLKSLLFGILLLLWLVASFAWWLGQRGKRPIIQHSADPLLRQQIAQHRAFIGTLSHELRTPLTALLAHTAIVHNQQ
SEPAVREHSLLTLEREAQRMARLVRDLLELHRLELSDELPLVPVNVALLAEEAIASVWVMADEAQIELQFEADPTHQRVL
AHPDRLKQVWLNLLMNCLRYCRAGDLVIVRVLASEQGLRCSIEDSGPGIAATDLPHVTEPLYRGVLDNEGSGLGLSLVKQ
ILARHHSTLQIESSTNPPTGTHIWWILPYD

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=34.9557522123894, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=259, Percent_Identity=29.7297297297297, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786783, Length=244, Percent_Identity=29.9180327868852, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=28.2407407407407, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=31.0043668122271, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789403, Length=220, Percent_Identity=28.6363636363636, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=214, Percent_Identity=28.9719626168224, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=227, Percent_Identity=24.2290748898678, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=23.8095238095238, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=231, Percent_Identity=25.5411255411255, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788713, Length=224, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=28.82096069869, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=222, Percent_Identity=25.6756756756757, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=227, Percent_Identity=24.6696035242291, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790861, Length=190, Percent_Identity=28.9473684210526, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 30345; Mature: 30345

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLPLKSLLFGILLLLWLVASFAWWLGQRGKRPIIQHSADPLLRQQIAQHRAFIGTLSH
CEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHH
ELRTPLTALLAHTAIVHNQQSEPAVREHSLLTLEREAQRMARLVRDLLELHRLELSDELP
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LVPVNVALLAEEAIASVWVMADEAQIELQFEADPTHQRVLAHPDRLKQVWLNLLMNCLRY
EEEHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
CRAGDLVIVRVLASEQGLRCSIEDSGPGIAATDLPHVTEPLYRGVLDNEGSGLGLSLVKQ
HCCCCEEEEEEECCCCCCEEEECCCCCCCEECCCCHHHHHHHHHCCCCCCCCCCHHHHHH
ILARHHSTLQIESSTNPPTGTHIWWILPYD
HHHCCCCEEEEECCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MIVLPLKSLLFGILLLLWLVASFAWWLGQRGKRPIIQHSADPLLRQQIAQHRAFIGTLSH
CEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHH
ELRTPLTALLAHTAIVHNQQSEPAVREHSLLTLEREAQRMARLVRDLLELHRLELSDELP
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LVPVNVALLAEEAIASVWVMADEAQIELQFEADPTHQRVLAHPDRLKQVWLNLLMNCLRY
EEEHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
CRAGDLVIVRVLASEQGLRCSIEDSGPGIAATDLPHVTEPLYRGVLDNEGSGLGLSLVKQ
HCCCCEEEEEEECCCCCCEEEECCCCCCCEECCCCHHHHHHHHHCCCCCCCCCCHHHHHH
ILARHHSTLQIESSTNPPTGTHIWWILPYD
HHHCCCCEEEEECCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]