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The map label for this gene is zntR [H]

Identifier: 159046500

GI number: 159046500

Start: 26181

End: 26609

Strand: Direct

Name: zntR [H]

Synonym: Dshi_3961

Alternate gene names: 159046500

Gene position: 26181-26609 (Clockwise)

Preceding gene: 159046488

Following gene: 159046501

Centisome position: 20.73

GC content: 61.07

Gene sequence:

>429_bases
ATGCTGACGATTGGGACGCTGGCGAAGAAGACCGGAACAAAGGTGCAGACCATCCGGTATTACGAGCAGATCGGACTTAT
GCCTGAGCCCGGCAGGACCGAGGGGGGCCAACGACGCTATGGCGACGCCGAACTCGACCGCTTGTCATTCGTCCGGCACG
CACGGCAACTGGGGTTCTCGTTGGACGCGATCCGTGAGCTCCTCGATCTCAGCGATCATCCGGGAAAGTCCTGCGCTGAG
GCGGATGCAATAGCCCGTCGGCAACTCAAACAGGTCGAGCAACGATTGGCGCGGCTCGAGGCGCTGCGGACGGAATTGAA
GCGGATGGTGCATGAGTGCAGCGGCGGACAGACTTCTGATTGCCGTGTGCTCGAGGTACTGCGCGACCATTCCGAATGCC
TGACCGACCATGAAGAGATCGGCGCCTGA

Upstream 100 bases:

>100_bases
CATCGATCGGCCAACAATCACCGATCTGTGAAACTCGGGTGAAGCTTGTGATGCGCACCGCATAAAGCTACACCCACTGT
AGGTAATGTGGGGAGCGGAA

Downstream 100 bases:

>100_bases
GCAATTTCGACGACCTTTGATCGGAACGCAAAAAGCCCGGTGTTAGTTACTCATTGGCAATTCACTAATTTGGATACCCG
GCATGGCGGAGCAGAGAAAC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MLTIGTLAKKTGTKVQTIRYYEQIGLMPEPGRTEGGQRRYGDAELDRLSFVRHARQLGFSLDAIRELLDLSDHPGKSCAE
ADAIARRQLKQVEQRLARLEALRTELKRMVHECSGGQTSDCRVLEVLRDHSECLTDHEEIGA

Sequences:

>Translated_142_residues
MLTIGTLAKKTGTKVQTIRYYEQIGLMPEPGRTEGGQRRYGDAELDRLSFVRHARQLGFSLDAIRELLDLSDHPGKSCAE
ADAIARRQLKQVEQRLARLEALRTELKRMVHECSGGQTSDCRVLEVLRDHSECLTDHEEIGA
>Mature_142_residues
MLTIGTLAKKTGTKVQTIRYYEQIGLMPEPGRTEGGQRRYGDAELDRLSFVRHARQLGFSLDAIRELLDLSDHPGKSCAE
ADAIARRQLKQVEQRLARLEALRTELKRMVHECSGGQTSDCRVLEVLRDHSECLTDHEEIGA

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=130, Percent_Identity=44.6153846153846, Blast_Score=104, Evalue=2e-24,
Organism=Escherichia coli, GI1786695, Length=126, Percent_Identity=32.5396825396825, Blast_Score=87, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16018; Mature: 16018

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTIGTLAKKTGTKVQTIRYYEQIGLMPEPGRTEGGQRRYGDAELDRLSFVRHARQLGFS
CCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
LDAIRELLDLSDHPGKSCAEADAIARRQLKQVEQRLARLEALRTELKRMVHECSGGQTSD
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
CRVLEVLRDHSECLTDHEEIGA
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTIGTLAKKTGTKVQTIRYYEQIGLMPEPGRTEGGQRRYGDAELDRLSFVRHARQLGFS
CCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
LDAIRELLDLSDHPGKSCAEADAIARRQLKQVEQRLARLEALRTELKRMVHECSGGQTSD
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
CRVLEVLRDHSECLTDHEEIGA
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]