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The map label for this gene is mntR [H]

Identifier: 159046488

GI number: 159046488

Start: 17795

End: 18253

Strand: Direct

Name: mntR [H]

Synonym: Dshi_3949

Alternate gene names: 159046488

Gene position: 17795-18253 (Clockwise)

Preceding gene: 159046486

Following gene: 159046500

Centisome position: 14.09

GC content: 62.96

Gene sequence:

>459_bases
ATGACAAAGCTACAATCACAAGGGCGTGAGCCATTCGAAGCGGTCGACCGGGCTCCCGAGGCGCAGGCCGATGGCTTTGC
GACCGTGCGTCAGGCACATGAAAGCGAGATGGCGGAGGATTACGTCGAACTGATCGCGGAACTGATCGAGACGCGCGGGG
AGGCCAGACCGGTCGAGATCGCCGAGCGGCTTGGCGTGAAGCCGCCGACCGTGACCAAGAACATCTCGCGGCTCAAGGCT
GCTGGTCTGGTCCGGCGGGAGCCATACCGCGCGATATTCCTCACCGATGCCGGGCAGGACCTCGCGGAGATCTGTCGACG
CCGCCACAGGGTCGTCGTCGCCTTTCTTCTGAGCCTGGGAATCGACGAAGAGACCGCGGAACGCGATGCGGAAGGGATCG
AGCATCACGTCAGCGGGACGACATTGGAGGCGTTCGAGCGACGGCTCAATCAGAAATGA

Upstream 100 bases:

>100_bases
CATCACCACGGCCTCCAAAGTAAAAAGTTAGACATGGCTAACTTATCTACCCGAAGCAAACAAGTTGTCAATCCCGCTGT
TTCGCTGCAAAGTCCCGAGT

Downstream 100 bases:

>100_bases
GCTCGCCTAGATGCACATTCGCGCGATTCTCTATCGGGACCTCGAGCTATCAGGTCTTCAAGCCGCTGACACGTTTGCGC
AATTTCGAAGCTCGCTAGCC

Product: DtxR family iron dependent repressor

Products: NA

Alternate protein names: Manganese transport regulator [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MTKLQSQGREPFEAVDRAPEAQADGFATVRQAHESEMAEDYVELIAELIETRGEARPVEIAERLGVKPPTVTKNISRLKA
AGLVRREPYRAIFLTDAGQDLAEICRRRHRVVVAFLLSLGIDEETAERDAEGIEHHVSGTTLEAFERRLNQK

Sequences:

>Translated_152_residues
MTKLQSQGREPFEAVDRAPEAQADGFATVRQAHESEMAEDYVELIAELIETRGEARPVEIAERLGVKPPTVTKNISRLKA
AGLVRREPYRAIFLTDAGQDLAEICRRRHRVVVAFLLSLGIDEETAERDAEGIEHHVSGTTLEAFERRLNQK
>Mature_151_residues
TKLQSQGREPFEAVDRAPEAQADGFATVRQAHESEMAEDYVELIAELIETRGEARPVEIAERLGVKPPTVTKNISRLKAA
GLVRREPYRAIFLTDAGQDLAEICRRRHRVVVAFLLSLGIDEETAERDAEGIEHHVSGTTLEAFERRLNQK

Specific function: In the presence of manganese, it represses the manganese transporter mntH [H]

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787038, Length=133, Percent_Identity=52.6315789473684, Blast_Score=134, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress [H]

EC number: NA

Molecular weight: Translated: 17063; Mature: 16932

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50944 HTH_DTXR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLQSQGREPFEAVDRAPEAQADGFATVRQAHESEMAEDYVELIAELIETRGEARPVEI
CCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AERLGVKPPTVTKNISRLKAAGLVRREPYRAIFLTDAGQDLAEICRRRHRVVVAFLLSLG
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHC
IDEETAERDAEGIEHHVSGTTLEAFERRLNQK
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TKLQSQGREPFEAVDRAPEAQADGFATVRQAHESEMAEDYVELIAELIETRGEARPVEI
CCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AERLGVKPPTVTKNISRLKAAGLVRREPYRAIFLTDAGQDLAEICRRRHRVVVAFLLSLG
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHC
IDEETAERDAEGIEHHVSGTTLEAFERRLNQK
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]