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The map label for this gene is regB [H]

Identifier: 158423727

GI number: 158423727

Start: 2419568

End: 2420881

Strand: Direct

Name: regB [H]

Synonym: AZC_2103

Alternate gene names: 158423727

Gene position: 2419568-2420881 (Clockwise)

Preceding gene: 158423726

Following gene: 158423728

Centisome position: 45.06

GC content: 64.84

Gene sequence:

>1314_bases
ATGCCCGTCGCCCAGCAAGACACCAGCGGGAACAAGAACCTCTTCCTGCTGATCCAGCTCCGCTGGCTGGCCGTGGCGGG
GCAGGTCTTCACCATCCTCGTGGTGGATGTCTGGCTTCACATCCGCCTGCCGCTCCAGGAGATGATCTCCGTCCTGCTGC
TGCTGGTCGGCCTCAATCTCGTGGCTCTCTGGCGCCACCGCAGCGAGGCGGAGGTCACAAATGTCGAACTGCTGGGCGAA
CTGATCCTCGACGTCGCGGCGCTGACGGCCCAGCTCTATCTCAGCGGCGGCGCCACCAACCCCTTCATCTCGCTCTATCT
GCTCCAGGTGGGGCTGGGAGCGGTGCTGCTCCAGCCCTGGTCGGCCTGGGTGCTGGTGGTGCTGACCAGCGCCTGCTTCG
TCTGGCTGATCGGCCAGTTTCGCCCGCTGCCTCTGCCGCATGACGACCATTCGACCCTGTTCAACCTGCATATCGGGGGC
ATGTTCGTCTGCTTCCTGCTGGCGGCGAGCCTGCTGGTGCAGTTCATCAGCCGCATCAGCGCGAACGTCCATGAGCGGGA
GCAGAGGCTGGCGGAACTGCGTCGCAAATCGGCGGAGGAGGACCTCATCGTCCGCATGGGCCTGCTCGCCTCGGGCGCGG
CCCATGAACTTGGAACGCCGCTCGCGACGCTCTCGGTGATCCTGAACGACTGGCAGCACATGGAGGCGGTGGAGGAGGAC
CCCGAGCTGATGGAGGACCTCTCCGAGATGCAGGCGCAGGTGGCGCGCTGCAAGATGATCGTTTCGGGCATCCTGATGTC
GTCGGGGCAGGCGCGCGGGGAGGGGACCCTTCGCACCACGGCCGACGTCTTCTTCGACGAACTGGTGGACGAGTGGCAGG
AGAGCCGCTCGCCGGCTGCGCTCGAATTCGTGAACGACCTGCCGCCGGATCTGCCCATCATCTCCGACGTCGCTCTGAAA
CAGGTGATTTTGAACGTCTTCGATAATGCGCTAGAAGCCTCTCCGGCATGGGTCGCCGTCAGCGTCACCCGTGCCGCAGA
CGCCATTGTGCTCGAGGTCCGCGACCATGGTCCGGGATTCGCCCCGGACATCCTTGCCGAGTTCGGCAAGCCCTACGGCT
CCACCAAGGGGCGGCCGGGTGGCGGGCTTGGTCTCTTCCTCGTGGTCAATGTGGTCCGCAAGCTTGGAGGCACCGTAACA
GCGCAGAACGAGGCTGACGGAGCGTCCGTCATCCTGGATTTGCCGCTGCATGCTCTCTCACCCGATGTCGATGACGGAGA
CCACCACACCCCGCCTGCTGATCGTCGAGGATGA

Upstream 100 bases:

>100_bases
CCATCTGGTCTATGCGCTGACGTGGTTTTCCCTTTGCGCTATGGCTCTGGGTGCGGCGGTTCTGGTGTGGAGGCGCCGCG
TCCGATAGGAGCGCGCCGCC

Downstream 100 bases:

>100_bases
CGCGTCCTTCGCGCGCGCCCTGCGCCGCTCCTTCGAACGGCGAGGCTACGAAGTCCGGCTGACCAGCAGTCTCGAAGGCG
TGCAGTCCGTGCTCTCCGAA

Product: two-component, sensor histidine protein kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MPVAQQDTSGNKNLFLLIQLRWLAVAGQVFTILVVDVWLHIRLPLQEMISVLLLLVGLNLVALWRHRSEAEVTNVELLGE
LILDVAALTAQLYLSGGATNPFISLYLLQVGLGAVLLQPWSAWVLVVLTSACFVWLIGQFRPLPLPHDDHSTLFNLHIGG
MFVCFLLAASLLVQFISRISANVHEREQRLAELRRKSAEEDLIVRMGLLASGAAHELGTPLATLSVILNDWQHMEAVEED
PELMEDLSEMQAQVARCKMIVSGILMSSGQARGEGTLRTTADVFFDELVDEWQESRSPAALEFVNDLPPDLPIISDVALK
QVILNVFDNALEASPAWVAVSVTRAADAIVLEVRDHGPGFAPDILAEFGKPYGSTKGRPGGGLGLFLVVNVVRKLGGTVT
AQNEADGASVILDLPLHALSPDVDDGDHHTPPADRRG

Sequences:

>Translated_437_residues
MPVAQQDTSGNKNLFLLIQLRWLAVAGQVFTILVVDVWLHIRLPLQEMISVLLLLVGLNLVALWRHRSEAEVTNVELLGE
LILDVAALTAQLYLSGGATNPFISLYLLQVGLGAVLLQPWSAWVLVVLTSACFVWLIGQFRPLPLPHDDHSTLFNLHIGG
MFVCFLLAASLLVQFISRISANVHEREQRLAELRRKSAEEDLIVRMGLLASGAAHELGTPLATLSVILNDWQHMEAVEED
PELMEDLSEMQAQVARCKMIVSGILMSSGQARGEGTLRTTADVFFDELVDEWQESRSPAALEFVNDLPPDLPIISDVALK
QVILNVFDNALEASPAWVAVSVTRAADAIVLEVRDHGPGFAPDILAEFGKPYGSTKGRPGGGLGLFLVVNVVRKLGGTVT
AQNEADGASVILDLPLHALSPDVDDGDHHTPPADRRG
>Mature_436_residues
PVAQQDTSGNKNLFLLIQLRWLAVAGQVFTILVVDVWLHIRLPLQEMISVLLLLVGLNLVALWRHRSEAEVTNVELLGEL
ILDVAALTAQLYLSGGATNPFISLYLLQVGLGAVLLQPWSAWVLVVLTSACFVWLIGQFRPLPLPHDDHSTLFNLHIGGM
FVCFLLAASLLVQFISRISANVHEREQRLAELRRKSAEEDLIVRMGLLASGAAHELGTPLATLSVILNDWQHMEAVEEDP
ELMEDLSEMQAQVARCKMIVSGILMSSGQARGEGTLRTTADVFFDELVDEWQESRSPAALEFVNDLPPDLPIISDVALKQ
VILNVFDNALEASPAWVAVSVTRAADAIVLEVRDHGPGFAPDILAEFGKPYGSTKGRPGGGLGLFLVVNVVRKLGGTVTA
QNEADGASVILDLPLHALSPDVDDGDHHTPPADRRG

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=268, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47539; Mature: 47407

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVAQQDTSGNKNLFLLIQLRWLAVAGQVFTILVVDVWLHIRLPLQEMISVLLLLVGLNL
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VALWRHRSEAEVTNVELLGELILDVAALTAQLYLSGGATNPFISLYLLQVGLGAVLLQPW
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SAWVLVVLTSACFVWLIGQFRPLPLPHDDHSTLFNLHIGGMFVCFLLAASLLVQFISRIS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
ANVHEREQRLAELRRKSAEEDLIVRMGLLASGAAHELGTPLATLSVILNDWQHMEAVEED
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCC
PELMEDLSEMQAQVARCKMIVSGILMSSGQARGEGTLRTTADVFFDELVDEWQESRSPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
LEFVNDLPPDLPIISDVALKQVILNVFDNALEASPAWVAVSVTRAADAIVLEVRDHGPGF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCC
APDILAEFGKPYGSTKGRPGGGLGLFLVVNVVRKLGGTVTAQNEADGASVILDLPLHALS
CHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCHHHCC
PDVDDGDHHTPPADRRG
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PVAQQDTSGNKNLFLLIQLRWLAVAGQVFTILVVDVWLHIRLPLQEMISVLLLLVGLNL
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VALWRHRSEAEVTNVELLGELILDVAALTAQLYLSGGATNPFISLYLLQVGLGAVLLQPW
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SAWVLVVLTSACFVWLIGQFRPLPLPHDDHSTLFNLHIGGMFVCFLLAASLLVQFISRIS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
ANVHEREQRLAELRRKSAEEDLIVRMGLLASGAAHELGTPLATLSVILNDWQHMEAVEED
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCC
PELMEDLSEMQAQVARCKMIVSGILMSSGQARGEGTLRTTADVFFDELVDEWQESRSPAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
LEFVNDLPPDLPIISDVALKQVILNVFDNALEASPAWVAVSVTRAADAIVLEVRDHGPGF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCC
APDILAEFGKPYGSTKGRPGGGLGLFLVVNVVRKLGGTVTAQNEADGASVILDLPLHALS
CHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCHHHCC
PDVDDGDHHTPPADRRG
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]