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The map label for this gene is cyoB [H]

Identifier: 158423723

GI number: 158423723

Start: 2415758

End: 2417770

Strand: Direct

Name: cyoB [H]

Synonym: AZC_2099

Alternate gene names: 158423723

Gene position: 2415758-2417770 (Clockwise)

Preceding gene: 158423722

Following gene: 158423724

Centisome position: 44.99

GC content: 62.54

Gene sequence:

>2013_bases
ATGTCTGCAGCCATCTCAACCCCCGTAAATCCCATCTTCGGGCGGCTCACGCTGGAGAGCCTCCCGCTGCATGAGCCGAT
CGTCGTCATGACGTTCTGCGTCGTGGCGCTGGGCGGCATCGCCGTCCTCGGTGCCCTGACGTACTTCCGCCTCTGGGGCT
ATCTCTGGAAGGAGTGGTTCACGAGCGTGGACCACAAGAAGATCGGCATCATGTACATGGTGCTCGGCATCATCATGCTG
CTGCGCGGCTTCGCCGACGCCATCATGATGCGCCTCCAGCAGGCCATCGCCTTCGGCGGTTCCGAGGGCTATCTGCCGGC
GCACCATTACGATCAGGTCTTCACGGCCCATGGCGTGATCATGATCTTCTTCGTGGCCATGCCGCTGGTCACGGGTTTCA
TGAACTTCGTGGTGCCGCTGCAGATCGGCGCCCGCGACGTGTCCTTCCCCTTCCTGAACAACTTCAGCTTCTGGATGACG
GTGGGCGGCGCGGTCCTGATCATGGCCTCGCTGTTCATCGGCGAGTTCGCCAAGACCGGCTGGCTCGCCTATCCGCCGCT
CTCGGGCATCGGATACAGTCCGGATGTCGGTGTCGATTATTATATCTGGGGCCTACAGGTCGCAGGTGTCGGCACAACAT
TGTCAGGCGTCAACCTGATCTGCACCATCATCAAGATGCGTGCCCCGGGCATGAGCCTGATGAAGATGCCGGTCTTCACC
TGGACCGCCCTCTGCACCAACGTGCTGATCGTCGCCAGCTTCCCGGTCCTGACCGCCTGCCTCGCGCTGCTGTCGCTGGA
CCGCTATGTCGGCACGAACTTCTTCACCAACGACTTCGGCGGCAGCCCGATGCTGTACGTGAACCTGATCTGGATCTGGG
GTCACCCCGAGGTCTACATCCTGGTTCTCCCGGTGTTCGGCATCTTCTCGGAGGTCACCTCGACCTTCGCGGGCAAGCGC
CTGTTCGGCTACACCTCGATGGTCTACGCCACGGTGGCGATCACCATCCTGTCCTACCTCGTGTGGCTGCACCACTTCTT
CACCATGGGCTCGGGCGCCAGCGTGAACTCGTTCTTCGGGATCACGACCATGATCATCTCCATCCCCACGGGTGCGAAGA
TGTTCAACTGGCTCTTCACCATGTACCGCGGCCGCATCCGCTTTGAAGTTCCGATGATGTACACGGTGGCCTTCATGCTC
ACCTTCGTCATCGGCGGCATGACGGGCGTGATGCTCGCCGTGCCCCCGGCGGACTTCGTGCTGCACAACAGCCTGTTCCT
CATCGCCCACTTCCACAACGTCATCATCGGTGGTGTGGTGTTCGGCATCTTCGCCGGCATCGCCTTCTGGTTCCCGAAGG
CCTTCGGCTTCAAGCTCGATCCCTTCTGGGGCAAGTGCTCGTTCTGGTTCTGGGTGGTGGGCTTCTACTTTGCCTTCATG
CCGCTCTACGTGCTGGGCTTCATGGGTGTCACCCGCCGCATGCGCGTCTTCGAGGACCCGTCCCTCCAGATCTGGTTCGT
CGTTGCCGCCTTCGGTGCCGCGCTCATCGCGCTCGGCATCCTGTGCTTCCTCATCCAGCTCGGCGTCAGCATCCTGCGCC
GCGACAAGCTGCGGGACACCACGGGCGACCCGTGGAACGCCCGCACGCTGGAGTGGGCGACGTCTTCCCCGCCGCCCGCC
TACAACTTCGCCTTCACCCCTGTCGTGCACGACCATGATGCCTGGTACGACATGAAGGCGCGCGGCTACGAGCGTCCGCT
CACCGGCTTCAAGCCGATCCACATGCCGCAGAACACCGGCGCCGGCGTGCTCCTCGCCGCCTGCAGCACGGCCATGGGCT
TCGGTCTCATCTGGTACATGTGGTGGCTGGTTGCGGCGAGCTTCATCGCTCTCCTCGCCATCGCCATCGGTCACACCTTC
AACTACCACCGCGACTTCTACATCTCCGCCGAGGAGGTGACGCGGACCGAGGATGAGCGGACCCGCCTCATCGCTGCGCA
GGTGAAAGCATGA

Upstream 100 bases:

>100_bases
TCGGCGGCCCCTCCGCTCCCGTATTCACCCCCATCAGCGCACCCTCGGCGGTTCCCCTGCCGAGCCTGCGCACCCTTTCC
AATTCCTGACGCGAGGCGTC

Downstream 100 bases:

>100_bases
GCTCTGCCGCCACCCCCCAGACCGGCGCGCCCGTCTTCTACGAAGTAGACGAGCACGCGCATCCCGAGGGCCACAGCACG
GCCCTCGGCTTCTGGATCTA

Product: cytochrome o ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 670; Mature: 669

Protein sequence:

>670_residues
MSAAISTPVNPIFGRLTLESLPLHEPIVVMTFCVVALGGIAVLGALTYFRLWGYLWKEWFTSVDHKKIGIMYMVLGIIML
LRGFADAIMMRLQQAIAFGGSEGYLPAHHYDQVFTAHGVIMIFFVAMPLVTGFMNFVVPLQIGARDVSFPFLNNFSFWMT
VGGAVLIMASLFIGEFAKTGWLAYPPLSGIGYSPDVGVDYYIWGLQVAGVGTTLSGVNLICTIIKMRAPGMSLMKMPVFT
WTALCTNVLIVASFPVLTACLALLSLDRYVGTNFFTNDFGGSPMLYVNLIWIWGHPEVYILVLPVFGIFSEVTSTFAGKR
LFGYTSMVYATVAITILSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKMFNWLFTMYRGRIRFEVPMMYTVAFML
TFVIGGMTGVMLAVPPADFVLHNSLFLIAHFHNVIIGGVVFGIFAGIAFWFPKAFGFKLDPFWGKCSFWFWVVGFYFAFM
PLYVLGFMGVTRRMRVFEDPSLQIWFVVAAFGAALIALGILCFLIQLGVSILRRDKLRDTTGDPWNARTLEWATSSPPPA
YNFAFTPVVHDHDAWYDMKARGYERPLTGFKPIHMPQNTGAGVLLAACSTAMGFGLIWYMWWLVAASFIALLAIAIGHTF
NYHRDFYISAEEVTRTEDERTRLIAAQVKA

Sequences:

>Translated_670_residues
MSAAISTPVNPIFGRLTLESLPLHEPIVVMTFCVVALGGIAVLGALTYFRLWGYLWKEWFTSVDHKKIGIMYMVLGIIML
LRGFADAIMMRLQQAIAFGGSEGYLPAHHYDQVFTAHGVIMIFFVAMPLVTGFMNFVVPLQIGARDVSFPFLNNFSFWMT
VGGAVLIMASLFIGEFAKTGWLAYPPLSGIGYSPDVGVDYYIWGLQVAGVGTTLSGVNLICTIIKMRAPGMSLMKMPVFT
WTALCTNVLIVASFPVLTACLALLSLDRYVGTNFFTNDFGGSPMLYVNLIWIWGHPEVYILVLPVFGIFSEVTSTFAGKR
LFGYTSMVYATVAITILSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKMFNWLFTMYRGRIRFEVPMMYTVAFML
TFVIGGMTGVMLAVPPADFVLHNSLFLIAHFHNVIIGGVVFGIFAGIAFWFPKAFGFKLDPFWGKCSFWFWVVGFYFAFM
PLYVLGFMGVTRRMRVFEDPSLQIWFVVAAFGAALIALGILCFLIQLGVSILRRDKLRDTTGDPWNARTLEWATSSPPPA
YNFAFTPVVHDHDAWYDMKARGYERPLTGFKPIHMPQNTGAGVLLAACSTAMGFGLIWYMWWLVAASFIALLAIAIGHTF
NYHRDFYISAEEVTRTEDERTRLIAAQVKA
>Mature_669_residues
SAAISTPVNPIFGRLTLESLPLHEPIVVMTFCVVALGGIAVLGALTYFRLWGYLWKEWFTSVDHKKIGIMYMVLGIIMLL
RGFADAIMMRLQQAIAFGGSEGYLPAHHYDQVFTAHGVIMIFFVAMPLVTGFMNFVVPLQIGARDVSFPFLNNFSFWMTV
GGAVLIMASLFIGEFAKTGWLAYPPLSGIGYSPDVGVDYYIWGLQVAGVGTTLSGVNLICTIIKMRAPGMSLMKMPVFTW
TALCTNVLIVASFPVLTACLALLSLDRYVGTNFFTNDFGGSPMLYVNLIWIWGHPEVYILVLPVFGIFSEVTSTFAGKRL
FGYTSMVYATVAITILSYLVWLHHFFTMGSGASVNSFFGITTMIISIPTGAKMFNWLFTMYRGRIRFEVPMMYTVAFMLT
FVIGGMTGVMLAVPPADFVLHNSLFLIAHFHNVIIGGVVFGIFAGIAFWFPKAFGFKLDPFWGKCSFWFWVVGFYFAFMP
LYVLGFMGVTRRMRVFEDPSLQIWFVVAAFGAALIALGILCFLIQLGVSILRRDKLRDTTGDPWNARTLEWATSSPPPAY
NFAFTPVVHDHDAWYDMKARGYERPLTGFKPIHMPQNTGAGVLLAACSTAMGFGLIWYMWWLVAASFIALLAIAIGHTFN
YHRDFYISAEEVTRTEDERTRLIAAQVKA

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=37.8167641325536, Blast_Score=325, Evalue=1e-88,
Organism=Escherichia coli, GI1786634, Length=651, Percent_Identity=65.1305683563748, Blast_Score=905, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=539, Percent_Identity=36.5491651205937, Blast_Score=334, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6226524, Length=329, Percent_Identity=42.2492401215805, Blast_Score=240, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6226523, Length=252, Percent_Identity=35.7142857142857, Blast_Score=137, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74744; Mature: 74613

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCC
>Mature Secondary Structure 
SAAISTPVNPIFGRLTLESLPLHEPIVVMTFCVVALGGIAVLGALTYFRLWGYLWKEWF
CCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSVDHKKIGIMYMVLGIIMLLRGFADAIMMRLQQAIAFGGSEGYLPAHHYDQVFTAHGVI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
MIFFVAMPLVTGFMNFVVPLQIGARDVSFPFLNNFSFWMTVGGAVLIMASLFIGEFAKTG
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
WLAYPPLSGIGYSPDVGVDYYIWGLQVAGVGTTLSGVNLICTIIKMRAPGMSLMKMPVFT
CEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
WTALCTNVLIVASFPVLTACLALLSLDRYVGTNFFTNDFGGSPMLYVNLIWIWGHPEVYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCEEE
LVLPVFGIFSEVTSTFAGKRLFGYTSMVYATVAITILSYLVWLHHFFTMGSGASVNSFFG
EHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
ITTMIISIPTGAKMFNWLFTMYRGRIRFEVPMMYTVAFMLTFVIGGMTGVMLAVPPADFV
HHHHEEECCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCHHCEEEEECCHHHH
LHNSLFLIAHFHNVIIGGVVFGIFAGIAFWFPKAFGFKLDPFWGKCSFWFWVVGFYFAFM
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHH
PLYVLGFMGVTRRMRVFEDPSLQIWFVVAAFGAALIALGILCFLIQLGVSILRRDKLRDT
HHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TGDPWNARTLEWATSSPPPAYNFAFTPVVHDHDAWYDMKARGYERPLTGFKPIHMPQNTG
CCCCCCCCEEEECCCCCCCCCCEEECCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGVLLAACSTAMGFGLIWYMWWLVAASFIALLAIAIGHTFNYHRDFYISAEEVTRTEDER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCCHHHH
TRLIAAQVKA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]