Click here to switch to the map view.

The map label for this gene is 158423644

Identifier: 158423644

GI number: 158423644

Start: 2330081

End: 2331574

Strand: Direct

Name: 158423644

Synonym: AZC_2020

Alternate gene names: NA

Gene position: 2330081-2331574 (Clockwise)

Preceding gene: 158423642

Following gene: 158423645

Centisome position: 43.39

GC content: 69.61

Gene sequence:

>1494_bases
ATGACCGAACTCTGCGACCTGACCGCCCTCGAACTGCGCGACGCCATCGCGCACAAGCGCCTCTCGCCGGTGGAGGTTCT
GGAGGCCTGTCTCGACCGCATCGAAGCGGTCAATCCCGCCGTCAACGCCATGGTCACGCTGGACGTGGAGGGCGCGCGCA
AGGCGGCGGTCGAGGCCGAGGCGGCGGTGATGCGCGGCGATGCGCTGGGTCCGCTCCACGGCCTCCCTCTGGCGGTTAAG
GACACGCAGGACGTGGGCGGGATGCGCACCACTTACGGCAGTCCGCTGTTCGCCGAGCACGTTCCGGCGGCGGATGCGGG
CAGCGTGGCGCGCCTGCGGGCGGCCGGCGCCATCATCGTCGGCAAGACCAACACGCCGGAATGGGCGGCCGGGGCCAATA
CCCGCAATCCCGTCTATGGCGCCACCGGCAATCCGTTCGATCCGCTCAAATCCTGCGCCGGCTCGTCCGGCGGCGCGGCG
GTGGCGCTCGCCTGCGGCATGACCCCCCTCGCCACCGGCTCCGACACCGGCGGCAGCCTGCGCAATCCGGCGGGCTTTTG
CGGCATTGTCGGCATGCGCCCTTCTTATGGCCTCGTGGCCAGCGAACGGCGCCTGCACGGCTGGTCGAGCCTGTCCACCG
ATGGCCCGATGGCCCGCAACGTCTCCGACACGGCGCTGATGCTCTCGGTCATGGCCAGCGACGATAGCCGCGATCCGCTG
GCCTATACGCTGCCGGGAGAACCCGTGCGAGCGCGACCGGGCCGCTGGACCGTCCCGGAGATCAATCTGAAGGAACTGCG
GCTCGCCTTCACGGAGGATTTCGGCTTCGCGCCGACGGAGCAGCAGATCCGCCGCGTCTTCCGTTCGCGGGTCGCAGCTT
TGGCGCCGCATTTTGCCACCGCTGAAGAGGCAGGGCCCGACTGTACGGGCGCGGACGACGCCTTCGCGGTGCTGCGGGCC
TCCATGTTCCTCTCCATGTTCGAGAAGATCCATGCCGAGAAGCCCCACATGCTGGGGCCGAACGTGACGGCGAACGTGAA
GGAGGGGCTCTCCTACAGCCTCTCCGATTATGCCCGCGCCGCCGCCACCCAGACGCGGATCTATCGCTCCTATCAGAGCT
TCTTCGCCACCCACGACGTGCTCATTTCCCCGACCATCACGCTGAGCCCGCGCCCGTGGTCGGAACCTCATCCGGCCGAG
ATCGACGGCGTGCCGACCCGCTCCTATTTCCACTGGCTGGCGCTGGCCTATGCGGTGACGCTCGCCGGCCATCCGGCCAT
CAGCCTGCCGCTGGGCGTGGACGAGGCGGGCATGCCGTTCGGCCTCCAGATCGTCGGGCCCCGCGGGGGCGATGCACTGG
TGCTCGGCGTCGCGAAGGCGCTTGAGACGGTCTGCGCGAGCGACGCCGCGCTTTGCCGCCCGGTGCCGGACCTCGCCGGC
CTTAAGGCGGCCCGTCCGCTGCGCGAGACCCCAGGCTTCATGACCTGGGAATGA

Upstream 100 bases:

>100_bases
TGAAGATTTCATCATCATCTGCACGCAGATTAAGCGGCGCATGATTTGCCGATTTAGAAAAAATTCGTACGATACGAAAA
ATCACCATCGGACCGCCGCG

Downstream 100 bases:

>100_bases
TCCGGGCGCGGACCTGACTCCCATCAAGCAGACGCCGCAAAGGCGCGCTCAAGAGCCATAACAAACCTTCCGAGGCTTCC
ATGTTGAAAAAGATTGCCGG

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MTELCDLTALELRDAIAHKRLSPVEVLEACLDRIEAVNPAVNAMVTLDVEGARKAAVEAEAAVMRGDALGPLHGLPLAVK
DTQDVGGMRTTYGSPLFAEHVPAADAGSVARLRAAGAIIVGKTNTPEWAAGANTRNPVYGATGNPFDPLKSCAGSSGGAA
VALACGMTPLATGSDTGGSLRNPAGFCGIVGMRPSYGLVASERRLHGWSSLSTDGPMARNVSDTALMLSVMASDDSRDPL
AYTLPGEPVRARPGRWTVPEINLKELRLAFTEDFGFAPTEQQIRRVFRSRVAALAPHFATAEEAGPDCTGADDAFAVLRA
SMFLSMFEKIHAEKPHMLGPNVTANVKEGLSYSLSDYARAAATQTRIYRSYQSFFATHDVLISPTITLSPRPWSEPHPAE
IDGVPTRSYFHWLALAYAVTLAGHPAISLPLGVDEAGMPFGLQIVGPRGGDALVLGVAKALETVCASDAALCRPVPDLAG
LKAARPLRETPGFMTWE

Sequences:

>Translated_497_residues
MTELCDLTALELRDAIAHKRLSPVEVLEACLDRIEAVNPAVNAMVTLDVEGARKAAVEAEAAVMRGDALGPLHGLPLAVK
DTQDVGGMRTTYGSPLFAEHVPAADAGSVARLRAAGAIIVGKTNTPEWAAGANTRNPVYGATGNPFDPLKSCAGSSGGAA
VALACGMTPLATGSDTGGSLRNPAGFCGIVGMRPSYGLVASERRLHGWSSLSTDGPMARNVSDTALMLSVMASDDSRDPL
AYTLPGEPVRARPGRWTVPEINLKELRLAFTEDFGFAPTEQQIRRVFRSRVAALAPHFATAEEAGPDCTGADDAFAVLRA
SMFLSMFEKIHAEKPHMLGPNVTANVKEGLSYSLSDYARAAATQTRIYRSYQSFFATHDVLISPTITLSPRPWSEPHPAE
IDGVPTRSYFHWLALAYAVTLAGHPAISLPLGVDEAGMPFGLQIVGPRGGDALVLGVAKALETVCASDAALCRPVPDLAG
LKAARPLRETPGFMTWE
>Mature_496_residues
TELCDLTALELRDAIAHKRLSPVEVLEACLDRIEAVNPAVNAMVTLDVEGARKAAVEAEAAVMRGDALGPLHGLPLAVKD
TQDVGGMRTTYGSPLFAEHVPAADAGSVARLRAAGAIIVGKTNTPEWAAGANTRNPVYGATGNPFDPLKSCAGSSGGAAV
ALACGMTPLATGSDTGGSLRNPAGFCGIVGMRPSYGLVASERRLHGWSSLSTDGPMARNVSDTALMLSVMASDDSRDPLA
YTLPGEPVRARPGRWTVPEINLKELRLAFTEDFGFAPTEQQIRRVFRSRVAALAPHFATAEEAGPDCTGADDAFAVLRAS
MFLSMFEKIHAEKPHMLGPNVTANVKEGLSYSLSDYARAAATQTRIYRSYQSFFATHDVLISPTITLSPRPWSEPHPAEI
DGVPTRSYFHWLALAYAVTLAGHPAISLPLGVDEAGMPFGLQIVGPRGGDALVLGVAKALETVCASDAALCRPVPDLAGL
KAARPLRETPGFMTWE

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=496, Percent_Identity=27.6209677419355, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI195972892, Length=500, Percent_Identity=27.4, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI166795287, Length=241, Percent_Identity=33.195020746888, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17537465, Length=504, Percent_Identity=25.5952380952381, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17543272, Length=451, Percent_Identity=27.0509977827051, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17538252, Length=292, Percent_Identity=29.4520547945205, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17556264, Length=229, Percent_Identity=32.7510917030568, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71990152, Length=296, Percent_Identity=28.7162162162162, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17538254, Length=231, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17556276, Length=195, Percent_Identity=31.7948717948718, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17556278, Length=195, Percent_Identity=31.7948717948718, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319685, Length=446, Percent_Identity=27.5784753363229, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320448, Length=232, Percent_Identity=30.1724137931034, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323950, Length=427, Percent_Identity=25.0585480093677, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356731, Length=494, Percent_Identity=26.3157894736842, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24644968, Length=512, Percent_Identity=26.7578125, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24648435, Length=497, Percent_Identity=25.7545271629779, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24648437, Length=497, Percent_Identity=25.7545271629779, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI45550774, Length=497, Percent_Identity=25.7545271629779, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24652985, Length=489, Percent_Identity=28.0163599182004, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI19922090, Length=489, Percent_Identity=28.0163599182004, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24652981, Length=489, Percent_Identity=28.0163599182004, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24652983, Length=489, Percent_Identity=28.0163599182004, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI161078093, Length=498, Percent_Identity=25.9036144578313, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24648113, Length=265, Percent_Identity=35.8490566037736, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24648441, Length=425, Percent_Identity=25.4117647058824, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24648439, Length=425, Percent_Identity=25.4117647058824, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 52424; Mature: 52293

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELCDLTALELRDAIAHKRLSPVEVLEACLDRIEAVNPAVNAMVTLDVEGARKAAVEAE
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHH
AAVMRGDALGPLHGLPLAVKDTQDVGGMRTTYGSPLFAEHVPAADAGSVARLRAAGAIIV
HHHHCCCCCCCCCCCCEEEECCHHCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHCCEEEE
GKTNTPEWAAGANTRNPVYGATGNPFDPLKSCAGSSGGAAVALACGMTPLATGSDTGGSL
ECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCC
RNPAGFCGIVGMRPSYGLVASERRLHGWSSLSTDGPMARNVSDTALMLSVMASDDSRDPL
CCCCCEEEEECCCCCCCCEECCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCE
AYTLPGEPVRARPGRWTVPEINLKELRLAFTEDFGFAPTEQQIRRVFRSRVAALAPHFAT
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHH
AEEAGPDCTGADDAFAVLRASMFLSMFEKIHAEKPHMLGPNVTANVKEGLSYSLSDYARA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCHHHHHHH
AATQTRIYRSYQSFFATHDVLISPTITLSPRPWSEPHPAEIDGVPTRSYFHWLALAYAVT
HHHHHHHHHHHHHHHHHCCEEECCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LAGHPAISLPLGVDEAGMPFGLQIVGPRGGDALVLGVAKALETVCASDAALCRPVPDLAG
HCCCCCEEECCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHCCHHHHCCCCHHHC
LKAARPLRETPGFMTWE
CHHCCCHHHCCCCCCCC
>Mature Secondary Structure 
TELCDLTALELRDAIAHKRLSPVEVLEACLDRIEAVNPAVNAMVTLDVEGARKAAVEAE
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHH
AAVMRGDALGPLHGLPLAVKDTQDVGGMRTTYGSPLFAEHVPAADAGSVARLRAAGAIIV
HHHHCCCCCCCCCCCCEEEECCHHCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHCCEEEE
GKTNTPEWAAGANTRNPVYGATGNPFDPLKSCAGSSGGAAVALACGMTPLATGSDTGGSL
ECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCC
RNPAGFCGIVGMRPSYGLVASERRLHGWSSLSTDGPMARNVSDTALMLSVMASDDSRDPL
CCCCCEEEEECCCCCCCCEECCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCE
AYTLPGEPVRARPGRWTVPEINLKELRLAFTEDFGFAPTEQQIRRVFRSRVAALAPHFAT
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHH
AEEAGPDCTGADDAFAVLRASMFLSMFEKIHAEKPHMLGPNVTANVKEGLSYSLSDYARA
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCHHHHHHH
AATQTRIYRSYQSFFATHDVLISPTITLSPRPWSEPHPAEIDGVPTRSYFHWLALAYAVT
HHHHHHHHHHHHHHHHHCCEEECCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LAGHPAISLPLGVDEAGMPFGLQIVGPRGGDALVLGVAKALETVCASDAALCRPVPDLAG
HCCCCCEEECCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHCCHHHHCCCCHHHC
LKAARPLRETPGFMTWE
CHHCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]