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The map label for this gene is garP [H]

Identifier: 158423645

GI number: 158423645

Start: 2331655

End: 2332875

Strand: Direct

Name: garP [H]

Synonym: AZC_2021

Alternate gene names: 158423645

Gene position: 2331655-2332875 (Clockwise)

Preceding gene: 158423644

Following gene: 158423646

Centisome position: 43.42

GC content: 64.29

Gene sequence:

>1221_bases
ATGTTGAAAAAGATTGCCGGCAATAAGGCCGCCATCGTCGGCTTCGCGCTTCTCTATCTGGCATTCTGCATCTCCTATAT
CGACCGGGCGGCCATGTCGCTGGCGCTGACCCATGTGGGCAAGGAGTTCAGTCTCAAGCCCGACGAACTCGGCGCCGTGC
TGAGCATCTTCTTCCTGGGCTATGCCATCATGCAGATTCCCGGCGGCTGGCTGGCCGACCGGTTCGGGTCGAAATACGTG
GTGATCGTCACGATCGCGGCGTGGTCCGTCTTCACCATCCTCACCAGCCAGGCCTGGTCGCTGGTGTCGCTGCTGGCGAT
CCGCTTCATCTTCGGTCTTGCGGAAGGTGGCTTCCCGGCGGCCAGCATCAAGGGCGTGTCGGAACTGGTGGCGAAGCCCA
ACCGGCCGAAGTTTACCGCCCTGCTCACCTCCTCCAATTATCTCGGCAGCATGGTGGCGCCGCTCATCATGGCGCCGCTC
ATCATCTCCTTCGGCTGGCGCCACGCCTTCGAGATCGTCGGCATCGCCGGCGTGGTCTTCGCGGTGGCCTATTTCCTGGC
CGTGCCCTACCGCCGCCCGGCGCCGCGCGCGGCGTCCGTGAACGGAAAGGCCCGCACTCCGGTGCGCGACCTCATGAAGA
ACCCGCTCATGTGGCAACTGCTCGTGGTGTGGTTCGGGCTCTCGTGCGTGAACAAGGGCCTCGATTCCTGGATGCCGACC
TACCTGCTCCAGCAGCGCGGCCTTGACCTCAAGGCGGTGGGCCTTCTCACCCCCGTGCCGTTCCTCATGGCCACCATCTC
CACCGCCATGGGCGGCTGGGTGATGACGCGCTTCTTCGCCCAGCGGGAGAAGTATCTGCTCATGGCCAGCGCGACCCTGA
CCGGCATCTTTCTCTATGCCATGTACAAGGCGGAGACGGTGGCTGGCGTCATCTTCTTCCAGTCGCTCGTCTATTTCTTC
AAATCCTTCGTGCTGGCGACGGTCATCGCCCTGCCCACGAAAGTGCTGGCGGACGACCAGATCGGCACCGGCATCGGCAT
CGTCAATGTGGGCGGGCAGGGCGCCGGTTCGGTCGCGCCCTATGTGATGGGCGTGCTGGTGGCGAGCTTTGGTGTCTATG
ACGCCGCCTTCAACTTCCTGCTGGTGATGACCGCCATGTCGGTCGTGGTCGCGGCCACCATCCGCACGCCCGCGCCGGAA
GCGGCCGCGCAGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCTTCATGACCTGGGAATGATCCGGGCGCGGACCTGACTCCCATCAAGCAGACGCCGCAAAGGCGCGCTCAAGAGCCATA
ACAAACCTTCCGAGGCTTCC

Downstream 100 bases:

>100_bases
GCCCTTCTCTTCCTTGTCAGAGGTGATCCATGTCCAAGCCCGCTCTGCCGTTCTCCCCCTGCCGCGAAGTCGGCGACATG
CTCTATCTGTCGGGCGAGGT

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: D-galactarate permease [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MLKKIAGNKAAIVGFALLYLAFCISYIDRAAMSLALTHVGKEFSLKPDELGAVLSIFFLGYAIMQIPGGWLADRFGSKYV
VIVTIAAWSVFTILTSQAWSLVSLLAIRFIFGLAEGGFPAASIKGVSELVAKPNRPKFTALLTSSNYLGSMVAPLIMAPL
IISFGWRHAFEIVGIAGVVFAVAYFLAVPYRRPAPRAASVNGKARTPVRDLMKNPLMWQLLVVWFGLSCVNKGLDSWMPT
YLLQQRGLDLKAVGLLTPVPFLMATISTAMGGWVMTRFFAQREKYLLMASATLTGIFLYAMYKAETVAGVIFFQSLVYFF
KSFVLATVIALPTKVLADDQIGTGIGIVNVGGQGAGSVAPYVMGVLVASFGVYDAAFNFLLVMTAMSVVVAATIRTPAPE
AAAQAA

Sequences:

>Translated_406_residues
MLKKIAGNKAAIVGFALLYLAFCISYIDRAAMSLALTHVGKEFSLKPDELGAVLSIFFLGYAIMQIPGGWLADRFGSKYV
VIVTIAAWSVFTILTSQAWSLVSLLAIRFIFGLAEGGFPAASIKGVSELVAKPNRPKFTALLTSSNYLGSMVAPLIMAPL
IISFGWRHAFEIVGIAGVVFAVAYFLAVPYRRPAPRAASVNGKARTPVRDLMKNPLMWQLLVVWFGLSCVNKGLDSWMPT
YLLQQRGLDLKAVGLLTPVPFLMATISTAMGGWVMTRFFAQREKYLLMASATLTGIFLYAMYKAETVAGVIFFQSLVYFF
KSFVLATVIALPTKVLADDQIGTGIGIVNVGGQGAGSVAPYVMGVLVASFGVYDAAFNFLLVMTAMSVVVAATIRTPAPE
AAAQAA
>Mature_406_residues
MLKKIAGNKAAIVGFALLYLAFCISYIDRAAMSLALTHVGKEFSLKPDELGAVLSIFFLGYAIMQIPGGWLADRFGSKYV
VIVTIAAWSVFTILTSQAWSLVSLLAIRFIFGLAEGGFPAASIKGVSELVAKPNRPKFTALLTSSNYLGSMVAPLIMAPL
IISFGWRHAFEIVGIAGVVFAVAYFLAVPYRRPAPRAASVNGKARTPVRDLMKNPLMWQLLVVWFGLSCVNKGLDSWMPT
YLLQQRGLDLKAVGLLTPVPFLMATISTAMGGWVMTRFFAQREKYLLMASATLTGIFLYAMYKAETVAGVIFFQSLVYFF
KSFVLATVIALPTKVLADDQIGTGIGIVNVGGQGAGSVAPYVMGVLVASFGVYDAAFNFLLVMTAMSVVVAATIRTPAPE
AAAQAA

Specific function: Uptake of D-galactarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=391, Percent_Identity=24.0409207161125, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI9945322, Length=303, Percent_Identity=26.4026402640264, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI9966811, Length=294, Percent_Identity=26.530612244898, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI21322234, Length=291, Percent_Identity=25.085910652921, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789515, Length=419, Percent_Identity=27.6849642004773, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789152, Length=422, Percent_Identity=28.436018957346, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367379, Length=396, Percent_Identity=24.4949494949495, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082320, Length=393, Percent_Identity=26.972010178117, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI2367193, Length=428, Percent_Identity=20.7943925233645, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17535049, Length=413, Percent_Identity=23.4866828087167, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI115533556, Length=304, Percent_Identity=25.9868421052632, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533554, Length=306, Percent_Identity=25.8169934640523, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583789, Length=260, Percent_Identity=30.3846153846154, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24584153, Length=360, Percent_Identity=23.8888888888889, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920686, Length=305, Percent_Identity=23.9344262295082, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24641682, Length=390, Percent_Identity=24.1025641025641, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI20130135, Length=294, Percent_Identity=26.8707482993197, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655271, Length=294, Percent_Identity=26.8707482993197, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19922400, Length=244, Percent_Identity=26.2295081967213, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24654215, Length=244, Percent_Identity=26.2295081967213, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24648416, Length=252, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356189, Length=252, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43583; Mature: 43583

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]