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The map label for this gene is 158423597

Identifier: 158423597

GI number: 158423597

Start: 2275450

End: 2276928

Strand: Direct

Name: 158423597

Synonym: AZC_1973

Alternate gene names: NA

Gene position: 2275450-2276928 (Clockwise)

Preceding gene: 158423592

Following gene: 158423599

Centisome position: 42.38

GC content: 68.09

Gene sequence:

>1479_bases
GTGAATTTCGCTTTGATGCTGACGATGGGGCATGCGCCTTGTGAACAGGCAGATCTGGAGAAGGATGGCGTGAAAAGTAT
CACTGTGGCCGAACAGAGCCTTCCGACATGGGCGAGCGCTGCGGACCTCGCACGCCGCATCGCGACCCGCGCCTGCACGG
CTAGCGCGGCGGTGGAAGAGCATCTGGCGCGGATCGCGGCGCTCGAACCGCACCTGAAGGCCTTCATCACGGTCGATGCG
GATGGGGCGCGGCGACGCGCGCGCGAACTTGATGTCAGCCCGCAACGGCAGGGGCCGCTGCATGGCCTGCCGGTCGCCAT
CAAGGACCTCACGCGCACGAGGGGCCTGCGCACCACGTTCGGCTCGCGCGCCTTTGCCGGCGAGGTGCCCGAGGCCGACG
ATCCCGTGGTGGCGCGGCTGCGGCGGGCGGGCGCCGTCATCATCGGCAAGACGAATACGCCGGAATTCGGCTTCGGTGCC
GTCTGCGTCAATGATCTGCAAGGGCCAACCGCAAATCCCTATGACCTCGTGCTCACCTCCGGCGGATCGTCGGGCGGCTC
CGCGGTGGCGGTGGCAACGGGCATGTCGGCGCTCGCGCATGGCACGGACTTCGGCGGATCGGTGCGCACGCCCGCGAGCT
TCTGCGGCGTGGTGTCGATCCGCCCCGCTATCGGCGTCATCGCCGATCCAGACCGTGAACTGGGCTGGACCGGCCTTGCC
ACCCATGGCGCCATGGGCCGTTCGGTCGCGGATGCGGCGCTGCTGCTTCAGGCTATGGCCGCGCCCAACGCCTATGATCC
GCTCTCGACCGCTCTGGCCGCCGGTCCGGATGCCCCGCCCAGACGGGTCGCCGTGACGCCGGATTTCGCCGTCGCGCCCG
TCTGCAAAGCGGTGCGCCGGCGCTTTGCACGTGCGGTGGACGAGATGCGTGCCGTTGTGGGCGAGGTCGTAGAGGCAACG
CCCGATTGCGCGGGTGCACCGCTGGCGTTCCGCACCTTGCGGGCGGCGCAGATCGCGCGAACCTATGGTGCATTCGTTGA
CGGAAACGTGCCGGTGTCACCCACCGTGCGCTGGAATGTGGAGGCGGCCCGCAGCCTCACGGCGCAGGACTATCTGGCGG
CGGAAGCCGCGCGGACAGCGCTCTGGCGCCGTTTCACCCGCTTCTTCGAGCAATATGATGTGCTGGTGACGCCGGCGGCC
TCTGTCCTGCCCTGGCCGAATGCCGAGGGAGAGCGCATGGAGATGGACGGGCGATCGCTGGCCGACATCCTTGATTATCT
GACGATCACTTTCATCGTCTCGCTGGTGGGTTTTCCGGTCGTCACGCTTCCGGCGCCCCGCCAGCCCGGAGAGGTCCCCT
TCGGCCTCCAGCTCATCGGGCGACCCGGCGCGGAGGCTGCGCTCATTGCGCTCGCGGCACGTCTGGAAGGCGAGGCGGGG
TTTTGTTGGTCACCCCCGCCATCTGTCAGCATGTTGTAA

Upstream 100 bases:

>100_bases
GGTCCCTGTCTGCATCATTCCATCCGGCATCCATCTTGCGTGGTCTCCTCTCAGCAAGTGGTATGCCAAAAGCTGAAAAT
GTATTTTCAGTCAGGGCTTT

Downstream 100 bases:

>100_bases
GTCCTGCGCGGCTGTCCAGGGGCCGTCACAGGGCGAGGTCGAGCACCTTGCCCTCGAACAGGCGGTCGTAGGAGCCCTGG
ATGTGCCGCCTCATGGCGTC

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MNFALMLTMGHAPCEQADLEKDGVKSITVAEQSLPTWASAADLARRIATRACTASAAVEEHLARIAALEPHLKAFITVDA
DGARRRARELDVSPQRQGPLHGLPVAIKDLTRTRGLRTTFGSRAFAGEVPEADDPVVARLRRAGAVIIGKTNTPEFGFGA
VCVNDLQGPTANPYDLVLTSGGSSGGSAVAVATGMSALAHGTDFGGSVRTPASFCGVVSIRPAIGVIADPDRELGWTGLA
THGAMGRSVADAALLLQAMAAPNAYDPLSTALAAGPDAPPRRVAVTPDFAVAPVCKAVRRRFARAVDEMRAVVGEVVEAT
PDCAGAPLAFRTLRAAQIARTYGAFVDGNVPVSPTVRWNVEAARSLTAQDYLAAEAARTALWRRFTRFFEQYDVLVTPAA
SVLPWPNAEGERMEMDGRSLADILDYLTITFIVSLVGFPVVTLPAPRQPGEVPFGLQLIGRPGAEAALIALAARLEGEAG
FCWSPPPSVSML

Sequences:

>Translated_492_residues
MNFALMLTMGHAPCEQADLEKDGVKSITVAEQSLPTWASAADLARRIATRACTASAAVEEHLARIAALEPHLKAFITVDA
DGARRRARELDVSPQRQGPLHGLPVAIKDLTRTRGLRTTFGSRAFAGEVPEADDPVVARLRRAGAVIIGKTNTPEFGFGA
VCVNDLQGPTANPYDLVLTSGGSSGGSAVAVATGMSALAHGTDFGGSVRTPASFCGVVSIRPAIGVIADPDRELGWTGLA
THGAMGRSVADAALLLQAMAAPNAYDPLSTALAAGPDAPPRRVAVTPDFAVAPVCKAVRRRFARAVDEMRAVVGEVVEAT
PDCAGAPLAFRTLRAAQIARTYGAFVDGNVPVSPTVRWNVEAARSLTAQDYLAAEAARTALWRRFTRFFEQYDVLVTPAA
SVLPWPNAEGERMEMDGRSLADILDYLTITFIVSLVGFPVVTLPAPRQPGEVPFGLQLIGRPGAEAALIALAARLEGEAG
FCWSPPPSVSML
>Mature_492_residues
MNFALMLTMGHAPCEQADLEKDGVKSITVAEQSLPTWASAADLARRIATRACTASAAVEEHLARIAALEPHLKAFITVDA
DGARRRARELDVSPQRQGPLHGLPVAIKDLTRTRGLRTTFGSRAFAGEVPEADDPVVARLRRAGAVIIGKTNTPEFGFGA
VCVNDLQGPTANPYDLVLTSGGSSGGSAVAVATGMSALAHGTDFGGSVRTPASFCGVVSIRPAIGVIADPDRELGWTGLA
THGAMGRSVADAALLLQAMAAPNAYDPLSTALAAGPDAPPRRVAVTPDFAVAPVCKAVRRRFARAVDEMRAVVGEVVEAT
PDCAGAPLAFRTLRAAQIARTYGAFVDGNVPVSPTVRWNVEAARSLTAQDYLAAEAARTALWRRFTRFFEQYDVLVTPAA
SVLPWPNAEGERMEMDGRSLADILDYLTITFIVSLVGFPVVTLPAPRQPGEVPFGLQLIGRPGAEAALIALAARLEGEAG
FCWSPPPSVSML

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=471, Percent_Identity=25.4777070063694, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI195972892, Length=238, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI166795287, Length=127, Percent_Identity=41.7322834645669, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17537465, Length=241, Percent_Identity=30.7053941908714, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17538252, Length=145, Percent_Identity=36.551724137931, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17543272, Length=458, Percent_Identity=24.235807860262, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71990152, Length=184, Percent_Identity=35.3260869565217, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17556264, Length=186, Percent_Identity=30.1075268817204, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17556276, Length=235, Percent_Identity=28.0851063829787, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17556278, Length=235, Percent_Identity=28.0851063829787, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538254, Length=131, Percent_Identity=35.8778625954198, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319685, Length=392, Percent_Identity=28.8265306122449, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323950, Length=462, Percent_Identity=22.2943722943723, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6320448, Length=129, Percent_Identity=34.8837209302326, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24648435, Length=258, Percent_Identity=32.1705426356589, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24648437, Length=258, Percent_Identity=32.1705426356589, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI45550774, Length=258, Percent_Identity=32.1705426356589, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24648113, Length=460, Percent_Identity=26.7391304347826, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI161078093, Length=501, Percent_Identity=26.9461077844311, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24648441, Length=426, Percent_Identity=24.4131455399061, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24648439, Length=426, Percent_Identity=24.4131455399061, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356731, Length=509, Percent_Identity=26.7190569744597, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24644968, Length=504, Percent_Identity=25, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24652985, Length=494, Percent_Identity=25.1012145748988, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19922090, Length=494, Percent_Identity=25.1012145748988, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24652981, Length=494, Percent_Identity=25.1012145748988, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24652983, Length=494, Percent_Identity=25.1012145748988, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 51692; Mature: 51692

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFALMLTMGHAPCEQADLEKDGVKSITVAEQSLPTWASAADLARRIATRACTASAAVEE
CCEEEEEEECCCCCCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HLARIAALEPHLKAFITVDADGARRRARELDVSPQRQGPLHGLPVAIKDLTRTRGLRTTF
HHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHC
GSRAFAGEVPEADDPVVARLRRAGAVIIGKTNTPEFGFGAVCVNDLQGPTANPYDLVLTS
CCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEEEC
GGSSGGSAVAVATGMSALAHGTDFGGSVRTPASFCGVVSIRPAIGVIADPDRELGWTGLA
CCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHHCEEEECCCCCEEECCCCCCCCCCCH
THGAMGRSVADAALLLQAMAAPNAYDPLSTALAAGPDAPPRRVAVTPDFAVAPVCKAVRR
HCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHH
RFARAVDEMRAVVGEVVEATPDCAGAPLAFRTLRAAQIARTYGAFVDGNVPVSPTVRWNV
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCEEECH
EAARSLTAQDYLAAEAARTALWRRFTRFFEQYDVLVTPAASVLPWPNAEGERMEMDGRSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHCCCCCCCCCEEECCCHHH
ADILDYLTITFIVSLVGFPVVTLPAPRQPGEVPFGLQLIGRPGAEAALIALAARLEGEAG
HHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCC
FCWSPPPSVSML
CCCCCCCCCCCC
>Mature Secondary Structure
MNFALMLTMGHAPCEQADLEKDGVKSITVAEQSLPTWASAADLARRIATRACTASAAVEE
CCEEEEEEECCCCCCCCCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HLARIAALEPHLKAFITVDADGARRRARELDVSPQRQGPLHGLPVAIKDLTRTRGLRTTF
HHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHC
GSRAFAGEVPEADDPVVARLRRAGAVIIGKTNTPEFGFGAVCVNDLQGPTANPYDLVLTS
CCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEEEC
GGSSGGSAVAVATGMSALAHGTDFGGSVRTPASFCGVVSIRPAIGVIADPDRELGWTGLA
CCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHHCEEEECCCCCEEECCCCCCCCCCCH
THGAMGRSVADAALLLQAMAAPNAYDPLSTALAAGPDAPPRRVAVTPDFAVAPVCKAVRR
HCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHH
RFARAVDEMRAVVGEVVEATPDCAGAPLAFRTLRAAQIARTYGAFVDGNVPVSPTVRWNV
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCEEECH
EAARSLTAQDYLAAEAARTALWRRFTRFFEQYDVLVTPAASVLPWPNAEGERMEMDGRSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHCCCCCCCCCEEECCCHHH
ADILDYLTITFIVSLVGFPVVTLPAPRQPGEVPFGLQLIGRPGAEAALIALAARLEGEAG
HHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCC
FCWSPPPSVSML
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]