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The map label for this gene is 158423592

Identifier: 158423592

GI number: 158423592

Start: 2270906

End: 2271265

Strand: Direct

Name: 158423592

Synonym: AZC_1968

Alternate gene names: NA

Gene position: 2270906-2271265 (Clockwise)

Preceding gene: 158423578

Following gene: 158423597

Centisome position: 42.29

GC content: 66.11

Gene sequence:

>360_bases
ATGGCGCAGGCGGGCGGAATCTCCATCCATGGGGTCGATATCGCGCAGGGCGTCGCCGCGCGGGGCCTGCAGGTGAAGGT
CTATGCCCTCGATCCGGAGCGGCGGCTGATCACCGAAGGCGTTCTCGGCGCCAATGGCGTGTTCGACGATCCCATCATCA
CCGGCGCCGGTATCACGGCGGGCACCTATGAGGTGGAGTTTGCGCTGGGCGCCTGGCTCAAGGCGAATGGCTATGGCGCG
CGGGAGGCGGCCTTCCTCGACATCGTGCCGTTCCGCTTCGTCGTCACGCGGGTGGAGGAGCATTACCATCTGCCGTTCAA
GTTCACGCCCTGGGGCATCCAGCTGTTTCGCGGCGTGTGA

Upstream 100 bases:

>100_bases
GCCGGCAGGGCGGCCCGAAGACCCGCGGGACGCGATGACCGAAGGGAATGAAACCGCTACCATGGGGTCTCTTCCTTCAC
GGTGATGCGGGGTCAGAGGC

Downstream 100 bases:

>100_bases
TCAGGCGAGGCGCCGCGACAGGCCGGTGAAGCGCTCCATCACCATGATGAGGGCGACGGTGAAGACGATCAGAACGCCGG
AGAGGGCGGCGATGGTCACG

Product: transthyretin-like protein

Products: NA

Alternate protein names: HIU hydrolase 2; HIUHase 2 [H]

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MAQAGGISIHGVDIAQGVAARGLQVKVYALDPERRLITEGVLGANGVFDDPIITGAGITAGTYEVEFALGAWLKANGYGA
REAAFLDIVPFRFVVTRVEEHYHLPFKFTPWGIQLFRGV

Sequences:

>Translated_119_residues
MAQAGGISIHGVDIAQGVAARGLQVKVYALDPERRLITEGVLGANGVFDDPIITGAGITAGTYEVEFALGAWLKANGYGA
REAAFLDIVPFRFVVTRVEEHYHLPFKFTPWGIQLFRGV
>Mature_118_residues
AQAGGISIHGVDIAQGVAARGLQVKVYALDPERRLITEGVLGANGVFDDPIITGAGITAGTYEVEFALGAWLKANGYGAR
EAAFLDIVPFRFVVTRVEEHYHLPFKFTPWGIQLFRGV

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 12846; Mature: 12715

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAGGISIHGVDIAQGVAARGLQVKVYALDPERRLITEGVLGANGVFDDPIITGAGITA
CCCCCCEEEECCHHHCCHHCCCEEEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCC
GTYEVEFALGAWLKANGYGAREAAFLDIVPFRFVVTRVEEHYHLPFKFTPWGIQLFRGV
CEEEEEEEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHEECCEEECCHHEEEECCC
>Mature Secondary Structure 
AQAGGISIHGVDIAQGVAARGLQVKVYALDPERRLITEGVLGANGVFDDPIITGAGITA
CCCCCEEEECCHHHCCHHCCCEEEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCC
GTYEVEFALGAWLKANGYGAREAAFLDIVPFRFVVTRVEEHYHLPFKFTPWGIQLFRGV
CEEEEEEEEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHEECCEEECCHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]