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The map label for this gene is rssA [H]

Identifier: 158423578

GI number: 158423578

Start: 2254945

End: 2256255

Strand: Direct

Name: rssA [H]

Synonym: AZC_1954

Alternate gene names: 158423578

Gene position: 2254945-2256255 (Clockwise)

Preceding gene: 158423577

Following gene: 158423592

Centisome position: 41.99

GC content: 69.49

Gene sequence:

>1311_bases
ATGCTGGCGCTGGGCGCGCTGCTGCTGAGCTTCGCGGCGTGGGAATATGCCAAGGTCGCGGCGCGCGATGCCTATGACAA
GCTGCTTATCGGCGGCGCGGTGCAGATTGCGGAAAACGTCTACGTGCAGGGGGGCGTTGTGGCGCTGGACCCCCCGGCCG
CCGCCTTTTCCACGCTCTCGGCCTATGACCTTGTCTTCTATCGCGTCACCGACCCGCGCGGGGTCGTGGTGGCGGGCTAT
GACGATCTGGCGAAGGGGGTCGGCGGCGCCGCGCTGCACCGCGGCGTCGTCCTGCGCGACGGCACCTATCAGGGGCAGCC
GGTGCGTATCGCGGCCCTCGGCAAGCAACTGGAGGACGCGGGCGGCGGCTGGGCGGAGATCGTGCTTGCCCAGACCATGC
GGGCCCGGGAAGCCCTGGCCTGGGATCTGACCACCAAGGCCGTCGCGCTCATCGCCGTGATGAGCCTGCTCGGCCTTCTG
GCAACGGCCCTCTCCCTGGGCCTCGCGTTTTCGCCTCTGACGCGGCTTGAGGGCGAGATCGCCGGCCGACGGCCCGATGA
CCTGCGTCCCATCCAGGTCTCGCCTCCACGGGAGGTGCGGGCGCTGGTTGGCGCCATCGACGGGTTCATGCGCCGGCTGG
AGGAGCGGATCGTCATGATGCAGCGCTTCATCGCCGATGCCGCCCACCAGATCCGCACGCCGCTCGCAGCTATCGATGCC
GAAGCGGAACTCTTAAGCGACGAACTGGACGATCCGGCGCGGATGGACCCGCTGCGGAACCGCATTGCGGATGTGGGGCG
CCTCGCCAGCCAGTTGCTCGATCACGCCATGGTGCTGCATCGGATGGAGACGGCGCGGCTGCAGCCGGTGGAGCTCAATG
CGCTGGCCAAGTCGGTTCTGGCGCAGACGGTGCCCCTGAGCCTTGAGCGGGAGGTGAGCATCACCTTCGTGCCGGCGCCC
GGCGAGGTGACGATTGCCGGAGACCCCATCAGCCTGCGGGAGGCCATCGCCAACCTCATCCACAATGCGGTCGTCCACGG
GGCGAGGGCGCGGCTCGCCGTCGAGGTTGGCGGGGACCAAGCCCATGCAGTGGTCACCGTGGGCGACGATGGACCGGGCA
TTCCCGATGGCGAGCGCGAGCGCCTCTGCGCGCCGTTCCAGCGCGGTGAGGGTTCCCATGGATCGGGTCTCGGGCTCGCC
ATCGCGGCCGAAGTGGCGCGGGCGCATGGCGGGGGCATCCGCTTTGAGATGCGCGAAGGCCTGTTTTGCGTGAGCCTGGT
GCTTGCCGTGGCGCCAGCCCGCGAGGCCTGA

Upstream 100 bases:

>100_bases
CCAGTCGAGATCCGGACAGAGCGCGGCCTTGGCTATCAGCTCGCGACTTGAAAGCCTGCGCACCTCGCTGCGCGCGCGCA
TCCTCGCCCTCGTCGGCATC

Downstream 100 bases:

>100_bases
GCCACCCGGCCGGGCCGGGTGGCACTGCGGCGCGATCAGGCGGAGAAGGTGACTTCCGCCGTGCCGAGGCCGGAGAAGGA
TGCGACGCAGGTGTCGCCGG

Product: ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MLALGALLLSFAAWEYAKVAARDAYDKLLIGGAVQIAENVYVQGGVVALDPPAAAFSTLSAYDLVFYRVTDPRGVVVAGY
DDLAKGVGGAALHRGVVLRDGTYQGQPVRIAALGKQLEDAGGGWAEIVLAQTMRAREALAWDLTTKAVALIAVMSLLGLL
ATALSLGLAFSPLTRLEGEIAGRRPDDLRPIQVSPPREVRALVGAIDGFMRRLEERIVMMQRFIADAAHQIRTPLAAIDA
EAELLSDELDDPARMDPLRNRIADVGRLASQLLDHAMVLHRMETARLQPVELNALAKSVLAQTVPLSLEREVSITFVPAP
GEVTIAGDPISLREAIANLIHNAVVHGARARLAVEVGGDQAHAVVTVGDDGPGIPDGERERLCAPFQRGEGSHGSGLGLA
IAAEVARAHGGGIRFEMREGLFCVSLVLAVAPAREA

Sequences:

>Translated_436_residues
MLALGALLLSFAAWEYAKVAARDAYDKLLIGGAVQIAENVYVQGGVVALDPPAAAFSTLSAYDLVFYRVTDPRGVVVAGY
DDLAKGVGGAALHRGVVLRDGTYQGQPVRIAALGKQLEDAGGGWAEIVLAQTMRAREALAWDLTTKAVALIAVMSLLGLL
ATALSLGLAFSPLTRLEGEIAGRRPDDLRPIQVSPPREVRALVGAIDGFMRRLEERIVMMQRFIADAAHQIRTPLAAIDA
EAELLSDELDDPARMDPLRNRIADVGRLASQLLDHAMVLHRMETARLQPVELNALAKSVLAQTVPLSLEREVSITFVPAP
GEVTIAGDPISLREAIANLIHNAVVHGARARLAVEVGGDQAHAVVTVGDDGPGIPDGERERLCAPFQRGEGSHGSGLGLA
IAAEVARAHGGGIRFEMREGLFCVSLVLAVAPAREA
>Mature_436_residues
MLALGALLLSFAAWEYAKVAARDAYDKLLIGGAVQIAENVYVQGGVVALDPPAAAFSTLSAYDLVFYRVTDPRGVVVAGY
DDLAKGVGGAALHRGVVLRDGTYQGQPVRIAALGKQLEDAGGGWAEIVLAQTMRAREALAWDLTTKAVALIAVMSLLGLL
ATALSLGLAFSPLTRLEGEIAGRRPDDLRPIQVSPPREVRALVGAIDGFMRRLEERIVMMQRFIADAAHQIRTPLAAIDA
EAELLSDELDDPARMDPLRNRIADVGRLASQLLDHAMVLHRMETARLQPVELNALAKSVLAQTVPLSLEREVSITFVPAP
GEVTIAGDPISLREAIANLIHNAVVHGARARLAVEVGGDQAHAVVTVGDDGPGIPDGERERLCAPFQRGEGSHGSGLGLA
IAAEVARAHGGGIRFEMREGLFCVSLVLAVAPAREA

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=285, Percent_Identity=29.1228070175439, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789403, Length=302, Percent_Identity=28.1456953642384, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790861, Length=267, Percent_Identity=32.9588014981273, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789808, Length=224, Percent_Identity=29.4642857142857, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=25.764192139738, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786783, Length=287, Percent_Identity=27.5261324041812, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693157, Length=210, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=209, Percent_Identity=28.2296650717703, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788279, Length=355, Percent_Identity=21.4084507042254, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=27.6595744680851, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=27.1929824561404, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787374, Length=285, Percent_Identity=25.2631578947368, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=28.310502283105, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081816, Length=222, Percent_Identity=29.2792792792793, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=23.5059760956175, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994928, Length=214, Percent_Identity=26.6355140186916, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786600, Length=218, Percent_Identity=27.0642201834862, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789149, Length=225, Percent_Identity=25.7777777777778, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI87082128, Length=241, Percent_Identity=27.3858921161826, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46134; Mature: 46134

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALGALLLSFAAWEYAKVAARDAYDKLLIGGAVQIAENVYVQGGVVALDPPAAAFSTLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEEECCEEEECCCHHHHHHHH
AYDLVFYRVTDPRGVVVAGYDDLAKGVGGAALHRGVVLRDGTYQGQPVRIAALGKQLEDA
HEEEEEEEEECCCEEEEECHHHHHHCCCCHHHHCCEEEECCCCCCCCEEEEHHHHHHHHC
GGGWAEIVLAQTMRAREALAWDLTTKAVALIAVMSLLGLLATALSLGLAFSPLTRLEGEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHH
AGRRPDDLRPIQVSPPREVRALVGAIDGFMRRLEERIVMMQRFIADAAHQIRTPLAAIDA
CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
EAELLSDELDDPARMDPLRNRIADVGRLASQLLDHAMVLHRMETARLQPVELNALAKSVL
HHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AQTVPLSLEREVSITFVPAPGEVTIAGDPISLREAIANLIHNAVVHGARARLAVEVGGDQ
HHHCCCCEECEEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
AHAVVTVGDDGPGIPDGERERLCAPFQRGEGSHGSGLGLAIAAEVARAHGGGIRFEMREG
EEEEEEECCCCCCCCCCCHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHCC
LFCVSLVLAVAPAREA
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLALGALLLSFAAWEYAKVAARDAYDKLLIGGAVQIAENVYVQGGVVALDPPAAAFSTLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEEECCEEEECCCHHHHHHHH
AYDLVFYRVTDPRGVVVAGYDDLAKGVGGAALHRGVVLRDGTYQGQPVRIAALGKQLEDA
HEEEEEEEEECCCEEEEECHHHHHHCCCCHHHHCCEEEECCCCCCCCEEEEHHHHHHHHC
GGGWAEIVLAQTMRAREALAWDLTTKAVALIAVMSLLGLLATALSLGLAFSPLTRLEGEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHH
AGRRPDDLRPIQVSPPREVRALVGAIDGFMRRLEERIVMMQRFIADAAHQIRTPLAAIDA
CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
EAELLSDELDDPARMDPLRNRIADVGRLASQLLDHAMVLHRMETARLQPVELNALAKSVL
HHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AQTVPLSLEREVSITFVPAPGEVTIAGDPISLREAIANLIHNAVVHGARARLAVEVGGDQ
HHHCCCCEECEEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
AHAVVTVGDDGPGIPDGERERLCAPFQRGEGSHGSGLGLAIAAEVARAHGGGIRFEMREG
EEEEEEECCCCCCCCCCCHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEHHCC
LFCVSLVLAVAPAREA
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA