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The map label for this gene is cpx [H]

Identifier: 158423418

GI number: 158423418

Start: 2052813

End: 2054525

Strand: Direct

Name: cpx [H]

Synonym: AZC_1794

Alternate gene names: 158423418

Gene position: 2052813-2054525 (Clockwise)

Preceding gene: 158423417

Following gene: 158423430

Centisome position: 38.23

GC content: 66.14

Gene sequence:

>1713_bases
ATGCGCAAACCCCAGAATCTCGTCTATGGCGTGGACGATCTGCCGCCCGCGCGCGTCGGCCTTTTGAGTGCGCTCCAGCA
GGTGGCCTTCCTCAGCGCGCTGCTGAGCGTGCCCAGCATCGCGCTCGCAAACCTCGGGCTCGATGACGACCAGTTCCTGC
GCCTGGCAGCGGCGACCCTGTTCTGTTCCGGCTTCGTGCTGGTCCTCCAGGGCTTTGGCATCGGCGGGGTCGGCGCCCGG
CTGTTCTATCCGCTCCAGTGCACCACGGCGGCCATTCCAGCGCTCGTCTATGCCTCGTCCGCCGGCCTGTCGCTCGCCGA
GAACTTCACCATGGTCGGCATGGTGGGCGTGTCCCAGGTGCTGTTTTCCTTTGTCATCTTCCGCCTGCGGGCGATCTTCA
CGGTGGAGGTGGCGGGGCTCGCGGTATTTCTCATCGGTGTCGGACTCGGCCAGCAGGGCCTCTTTCTCGTGCTGGACCTG
CCGCCGGACAGGCCCGACGCCATCGCCCATCTCACCATCGTCGGGGTGACGCTGGCGACGCTGGTCATCCTGCATGTGTA
TGTGCAAAGCCGGTTAAGGCTGTTCACCAACCTCATCGGCCTCTGCGTGGGGATGGTACTGAGCGTCGCGCTGGGCCAAC
TCGATCCCCATGACCTGCGCCTGTTCGCGGATGCGCGCGTCGTGGATTTCCCCCGTCCGCCGCTTTTCGGCTGGGCCTTC
AACCTCGGCGCGGTCATCCCCTTCATGGTCACCGGCTTCGTCTTCGCGCTCACCTCCATGGGCGTGCAGACCATTGCCCA
GCGCAACAATGACCGCGACTGGAAGAGCCCGGACCTGGTCTCCATCGGCCGGGGCATCCGTGCGGAAGGCGTGATGCATA
TGATGGCGGGTTTTCTGAACGCCATGCCCATGGTGGCGTCGGGCGGCGCAGTGGCGCTGGCGGCGGCCTCCGGCTGCACG
GCACGAGCGCTCGCCTTCTGGACCGGCGGCCTGTTGATGACCTTCTCGCTCCTACCCAAGGTGATCGGCTTCTGGTTGCT
GATGCCTGTCTCGGTCACAGGCGCGCTCTTCATCTTCCTGTCCACCTTCACGACGGTGAACGGCATCCAGCTTGTGGCGA
GCCGGGTGCTGGATGCCCGCAAGGTGTTGGCGATCGGAATGGGCTTCGTCGCCGCCATCGCCTACGAGCCACTGCACCGG
TTGCTGGACGGGCAGGTGCCGGGCCTGCGGCTGTTCACCTTCTCCGCCTTCGCGGTGTCCATCCTCGTCACGGTAGTGCT
GCTCGCCATCTTCCGCATCGGCGTCACCCGCAAGGTGGTGCGGCGCTTTCCGGCCAGCGGTGCCCGGCATGACGACGTGG
CGAACTTCATCGAGGCCGAGGGCGCGCGGTGGAGCGCGCGGGTGGACGTGGTGCAGCGCGCCGCGCAGGTGACCTGGCAT
GCGCTGGAACTGATCGGCCGCGATTATGTGGATCCCGAACGGCCGGTGATCGAGGTGACCACCCGCTATAACGATATCCT
GTTCGACATCGTGCTGCGCTACGAGGGCACGGCGCCGGCCCTGGCGAGCCGCCCGCCGACGGCGGAGGAACTGCTGGAAA
ATCCTGCGCTGGCGGAGCAGTTGACGGGCTTCCTCATTACCCGCCTCGCGCCGGACCTGAAGATCCAGCGCATCGGCAGT
TCGTGGGAACTGCACTTCCGCCTGCCGGTATGA

Upstream 100 bases:

>100_bases
GAGCCTGCACGGCTGGTGGTTCGATCTCGAAAGCGGTGACCTCTGGGTCACGGATGCTCCCGGAACGCCTCTGATGCCGG
CCACCTGAGCCGGCCCCCCC

Downstream 100 bases:

>100_bases
GGCGGGAGCGGGTGTACCCGCCCCCGCATAGGATCAGCCGGCGATGGCCGTCAGCTTGTCCAGCAGCGCCTGAGGGATCT
TCACGCCCTCGCGCGCGGTG

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MRKPQNLVYGVDDLPPARVGLLSALQQVAFLSALLSVPSIALANLGLDDDQFLRLAAATLFCSGFVLVLQGFGIGGVGAR
LFYPLQCTTAAIPALVYASSAGLSLAENFTMVGMVGVSQVLFSFVIFRLRAIFTVEVAGLAVFLIGVGLGQQGLFLVLDL
PPDRPDAIAHLTIVGVTLATLVILHVYVQSRLRLFTNLIGLCVGMVLSVALGQLDPHDLRLFADARVVDFPRPPLFGWAF
NLGAVIPFMVTGFVFALTSMGVQTIAQRNNDRDWKSPDLVSIGRGIRAEGVMHMMAGFLNAMPMVASGGAVALAAASGCT
ARALAFWTGGLLMTFSLLPKVIGFWLLMPVSVTGALFIFLSTFTTVNGIQLVASRVLDARKVLAIGMGFVAAIAYEPLHR
LLDGQVPGLRLFTFSAFAVSILVTVVLLAIFRIGVTRKVVRRFPASGARHDDVANFIEAEGARWSARVDVVQRAAQVTWH
ALELIGRDYVDPERPVIEVTTRYNDILFDIVLRYEGTAPALASRPPTAEELLENPALAEQLTGFLITRLAPDLKIQRIGS
SWELHFRLPV

Sequences:

>Translated_570_residues
MRKPQNLVYGVDDLPPARVGLLSALQQVAFLSALLSVPSIALANLGLDDDQFLRLAAATLFCSGFVLVLQGFGIGGVGAR
LFYPLQCTTAAIPALVYASSAGLSLAENFTMVGMVGVSQVLFSFVIFRLRAIFTVEVAGLAVFLIGVGLGQQGLFLVLDL
PPDRPDAIAHLTIVGVTLATLVILHVYVQSRLRLFTNLIGLCVGMVLSVALGQLDPHDLRLFADARVVDFPRPPLFGWAF
NLGAVIPFMVTGFVFALTSMGVQTIAQRNNDRDWKSPDLVSIGRGIRAEGVMHMMAGFLNAMPMVASGGAVALAAASGCT
ARALAFWTGGLLMTFSLLPKVIGFWLLMPVSVTGALFIFLSTFTTVNGIQLVASRVLDARKVLAIGMGFVAAIAYEPLHR
LLDGQVPGLRLFTFSAFAVSILVTVVLLAIFRIGVTRKVVRRFPASGARHDDVANFIEAEGARWSARVDVVQRAAQVTWH
ALELIGRDYVDPERPVIEVTTRYNDILFDIVLRYEGTAPALASRPPTAEELLENPALAEQLTGFLITRLAPDLKIQRIGS
SWELHFRLPV
>Mature_570_residues
MRKPQNLVYGVDDLPPARVGLLSALQQVAFLSALLSVPSIALANLGLDDDQFLRLAAATLFCSGFVLVLQGFGIGGVGAR
LFYPLQCTTAAIPALVYASSAGLSLAENFTMVGMVGVSQVLFSFVIFRLRAIFTVEVAGLAVFLIGVGLGQQGLFLVLDL
PPDRPDAIAHLTIVGVTLATLVILHVYVQSRLRLFTNLIGLCVGMVLSVALGQLDPHDLRLFADARVVDFPRPPLFGWAF
NLGAVIPFMVTGFVFALTSMGVQTIAQRNNDRDWKSPDLVSIGRGIRAEGVMHMMAGFLNAMPMVASGGAVALAAASGCT
ARALAFWTGGLLMTFSLLPKVIGFWLLMPVSVTGALFIFLSTFTTVNGIQLVASRVLDARKVLAIGMGFVAAIAYEPLHR
LLDGQVPGLRLFTFSAFAVSILVTVVLLAIFRIGVTRKVVRRFPASGARHDDVANFIEAEGARWSARVDVVQRAAQVTWH
ALELIGRDYVDPERPVIEVTTRYNDILFDIVLRYEGTAPALASRPPTAEELLENPALAEQLTGFLITRLAPDLKIQRIGS
SWELHFRLPV

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082178, Length=415, Percent_Identity=22.6506024096386, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790087, Length=411, Percent_Identity=21.8978102189781, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082181, Length=336, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 61452; Mature: 61452

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCEEEECCCCEEEEEECCC
>Mature Secondary Structure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HHHHHHHHHCCCCEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11792842; 8162194 [H]