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The map label for this gene is icfA [H]

Identifier: 158423417

GI number: 158423417

Start: 2051841

End: 2052800

Strand: Direct

Name: icfA [H]

Synonym: AZC_1793

Alternate gene names: 158423417

Gene position: 2051841-2052800 (Clockwise)

Preceding gene: 158423416

Following gene: 158423418

Centisome position: 38.21

GC content: 66.25

Gene sequence:

>960_bases
GTGCTTTGCCGGCTCTGGCGGGTCATCGGCGCCCGTGCGCCACGGCGGCTTGCGGCCGCGACGCTTCGCTCAAAGCCGGC
TGCGCTTTCTCTGAGGCGCGCGGTCTGCCGTCAGACACCTCATCTATTTCTGCGCGGATCGAAAGTTCTTCCTCGAACAT
TCCGGGGCGTGCAAAGGCACGAGATTCGAGGCATGATCGGCAATACTGCCCCGCTCGCCTCGATACGCGCGCATCTTGAG
GAACATGGGATGATCGACGACAGTCATACGGGTGATACTCCGTCCGCGTGCGCCGCCGAATGCCGGGATGTTGATCATCT
TCTTGAGGGTGTCCGCCGCTTCAAGGCACGCTTCTACGACGAAGCGCCTGCGCTGATGCAGGGGCTGGTCGAGAAGGGCC
AGAAGCCGGCGGTCCTGATGATCTCCTGTTCCGACTCGCGCGTCGATCCTGCGCTCCTGACGGGGGCCCTGCCGGGCGAA
CTGTTCGTCGTGCGGAACGTCGCCAATCTCGTGCCCGCCTATGCCCCGGACGACGGGCTGCACGGAACAGGCGCGGCGCT
GGAATATGCGGTGCGTGACCTCGGCGTCGATCACATCGTGGTGCTGGGGCACGCCCATTGCGGGGGCATCAAGGCGATGC
TGGCGACCGCCGGTGGCGAGCGCCCGCCGCGCGAGTTCGTGGGGCCGTGGGTGGAGATGGCGCTCGCCGCCAGCCGCCTG
CATCTGCCCGCCGAGGATGGCGAACAGCGCGAGATGCCCCTCGACCATCTCAAGGCCGTGCCCTTCCTTGCCGAGCGTGC
CTCAATCCTCGGCTCGCTGGACAATCTCATGACCTATCCCTGGGTCCGCGAGCGCGTCGAGGCCGGATCGCTGAGCCTGC
ACGGCTGGTGGTTCGATCTCGAAAGCGGTGACCTCTGGGTCACGGATGCTCCCGGAACGCCTCTGATGCCGGCCACCTGA

Upstream 100 bases:

>100_bases
CACGCTCGCCGCCGCACGCGCCCACCGGGCACCGGCACCGCTGCACTGAGCCGCCACGCTGCCGCTGCTTCGGTAGCCGT
CGCCCGCGCCATCCCTGAGC

Downstream 100 bases:

>100_bases
GCCGGCCCCCCCATGCGCAAACCCCAGAATCTCGTCTATGGCGTGGACGATCTGCCGCCCGCGCGCGTCGGCCTTTTGAG
TGCGCTCCAGCAGGTGGCCT

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MLCRLWRVIGARAPRRLAAATLRSKPAALSLRRAVCRQTPHLFLRGSKVLPRTFRGVQRHEIRGMIGNTAPLASIRAHLE
EHGMIDDSHTGDTPSACAAECRDVDHLLEGVRRFKARFYDEAPALMQGLVEKGQKPAVLMISCSDSRVDPALLTGALPGE
LFVVRNVANLVPAYAPDDGLHGTGAALEYAVRDLGVDHIVVLGHAHCGGIKAMLATAGGERPPREFVGPWVEMALAASRL
HLPAEDGEQREMPLDHLKAVPFLAERASILGSLDNLMTYPWVRERVEAGSLSLHGWWFDLESGDLWVTDAPGTPLMPAT

Sequences:

>Translated_319_residues
MLCRLWRVIGARAPRRLAAATLRSKPAALSLRRAVCRQTPHLFLRGSKVLPRTFRGVQRHEIRGMIGNTAPLASIRAHLE
EHGMIDDSHTGDTPSACAAECRDVDHLLEGVRRFKARFYDEAPALMQGLVEKGQKPAVLMISCSDSRVDPALLTGALPGE
LFVVRNVANLVPAYAPDDGLHGTGAALEYAVRDLGVDHIVVLGHAHCGGIKAMLATAGGERPPREFVGPWVEMALAASRL
HLPAEDGEQREMPLDHLKAVPFLAERASILGSLDNLMTYPWVRERVEAGSLSLHGWWFDLESGDLWVTDAPGTPLMPAT
>Mature_319_residues
MLCRLWRVIGARAPRRLAAATLRSKPAALSLRRAVCRQTPHLFLRGSKVLPRTFRGVQRHEIRGMIGNTAPLASIRAHLE
EHGMIDDSHTGDTPSACAAECRDVDHLLEGVRRFKARFYDEAPALMQGLVEKGQKPAVLMISCSDSRVDPALLTGALPGE
LFVVRNVANLVPAYAPDDGLHGTGAALEYAVRDLGVDHIVVLGHAHCGGIKAMLATAGGERPPREFVGPWVEMALAASRL
HLPAEDGEQREMPLDHLKAVPFLAERASILGSLDNLMTYPWVRERVEAGSLSLHGWWFDLESGDLWVTDAPGTPLMPAT

Specific function: Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation [H]

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=214, Percent_Identity=34.5794392523364, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786318, Length=212, Percent_Identity=31.6037735849057, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25147564, Length=233, Percent_Identity=28.3261802575107, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI115532990, Length=244, Percent_Identity=23.3606557377049, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324292, Length=222, Percent_Identity=28.3783783783784, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 34751; Mature: 34751

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCRLWRVIGARAPRRLAAATLRSKPAALSLRRAVCRQTPHLFLRGSKVLPRTFRGVQRH
CHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
EIRGMIGNTAPLASIRAHLEEHGMIDDSHTGDTPSACAAECRDVDHLLEGVRRFKARFYD
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
EAPALMQGLVEKGQKPAVLMISCSDSRVDPALLTGALPGELFVVRNVANLVPAYAPDDGL
CCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
HGTGAALEYAVRDLGVDHIVVLGHAHCGGIKAMLATAGGERPPREFVGPWVEMALAASRL
CCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
HLPAEDGEQREMPLDHLKAVPFLAERASILGSLDNLMTYPWVRERVEAGSLSLHGWWFDL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEEEEE
ESGDLWVTDAPGTPLMPAT
CCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MLCRLWRVIGARAPRRLAAATLRSKPAALSLRRAVCRQTPHLFLRGSKVLPRTFRGVQRH
CHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
EIRGMIGNTAPLASIRAHLEEHGMIDDSHTGDTPSACAAECRDVDHLLEGVRRFKARFYD
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
EAPALMQGLVEKGQKPAVLMISCSDSRVDPALLTGALPGELFVVRNVANLVPAYAPDDGL
CCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
HGTGAALEYAVRDLGVDHIVVLGHAHCGGIKAMLATAGGERPPREFVGPWVEMALAASRL
CCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
HLPAEDGEQREMPLDHLKAVPFLAERASILGSLDNLMTYPWVRERVEAGSLSLHGWWFDL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEEEEE
ESGDLWVTDAPGTPLMPAT
CCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584776 [H]