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The map label for this gene is ureC [H]

Identifier: 158423390

GI number: 158423390

Start: 2017235

End: 2018950

Strand: Direct

Name: ureC [H]

Synonym: AZC_1766

Alternate gene names: 158423390

Gene position: 2017235-2018950 (Clockwise)

Preceding gene: 158423389

Following gene: 158423391

Centisome position: 37.57

GC content: 66.2

Gene sequence:

>1716_bases
ATGACCAAGGCCCGTATGTCCCGTTCTGCTTATGCGCACATGTTCGGCCCCACGGTGGGCGACAAGGTGCGCCTCGCCGA
CACCGCGCTCTATATCGAGATCGAGAAGGACTTCACCGTCCATGGCGAGGAGGTGAAGTTCGGCGGCGGCAAGGTGATCC
GCGACGGCATGGGCCAGAGCCAGGTGGCCAATGCCGACGGCGCGGTGGACACCGTCATCACCAATGCGGTGATCCTCGAT
CACTGGGGCATCGTGAAAGCGGACGTCGGCCTGAAAGACGGGCGCATCTTCAAGATCGGCAAGGCCGGCAATCCCGATGT
GCAGAGCGGCGTCGACATCATCATCGGTCCCGGCACGGAGGTGATTGCGGGCGAGGGCAAGATCCTCACCGCCGGCGGCT
TCGACAGCCACATCCATTTCATCTGCCCGCAGCAGATCGAGGAGGCGCTGGCCTCCGGCGTCACCACCATGCTGGGCGGC
GGCACCGGTCCGGCCACCGGCACCTTCGCCACCACCTGCACCCCCGGCCCGTGGCACATCGCCCGCATGATCGAGGCGGC
GGATGCCTTCCCCATGAACCTTGCCTTCGCGGGCAAGGGCAATGCCTCCCAGCCCAAGGCGCTGGAAGAGATGGTGCGTG
CCGGCGCCTGCGCGCTGAAGCTCCATGAGGACTGGGGCACCACGCCCGCCGCCATCGATACCTGCCTCTCGGTGGCCGAT
GCCTTCGACATTCAGGTGATGATCCACACGGACACGCTGAACGAAAGCGGCTTCGTGGAGGACACCATCGCCGCCTTCAA
GGGCCGCACCATCCATGCCTTCCACACGGAAGGTGCGGGCGGCGGCCACGCGCCGGACATCATCAAGGTGGCGGGCCTGC
CCAACGTGCTGCCGTCCTCCACCAATCCGACCCGGCCCTATACGCGCAACACCATCGACGAGCATCTCGACATGCTCATG
GTGTGCCACCACCTCTCGCCGTCCATCCCCGAAGACCTCGCCTTCGCCGAGAGCCGCATCCGCAAGGAGACCATCGCGGC
CGAGGACATCCTGCACGACATCGGCGCCCTCTCCATGATGAGCTCCGACAGCCAGGCCATGGGCCGCGTGGGCGAGGTGG
TGATCCGCACCTGGCAGACGGCGGATAAGATGAAGCGCCAGCGCGGCGCGCTGCCCGGCGAGAGCGGCGGCAACGACAAT
CTGCGCGCCCGCCGCTATGTGGCGAAATACACCATCAACCCGGCCATCGCCCATGGCGTGTCGAAGCACATCGGCTCGGT
GGAGGCCGGCAAGCTCGCCGACCTCGTGCTGTGGTCGCCGGCCTTCTTCGGCGTCAAGCCGGATCTGGTGCTGAAGGGCG
GCTCCATCGCGGTGGCCCAGATGGGCGATCCCAACGCCTCCATTCCGACCCCGCAGCCGGTGCATTACAGGCCCATGTTC
GGTGCCTATGGCCGCGCCCGCACCCATTCCAGCCTGACCTTCGTCTCCAAGGCGGCAGTGGAGGATGGTCTCGCCGCCCG
GCTCCAGACGGCCAAGACGCTGGTGGCGGTGGAGAATGTCCGTTCCGGCATTTCCAAAAAGGACATGGTGCTGAACGGCG
CCACCCCCCATATCGAGGTGGACCCGGAGACCTATGACGTGCGCGCCGACGGCGAGCTTCTGGTCTGCGAGCCCGCGGAC
GTGCTGCCCATGGCGCAGCGCTACTTTTTGTTCTAA

Upstream 100 bases:

>100_bases
GAGTTCAAGGTGGCGGTGAACGTGCGCTGCCTCGACGGCGTGGACCTGAAAGCGCTGACCCCCCGCGAATTCGACGGCGC
GAGCCTCTGAAGGATACGCC

Downstream 100 bases:

>100_bases
CCGGGCGCGACCGCCTTCGCCGGCCGCTGCCTCGGGAGCCTCACATGATCCGTTCGACCAAGATCGTCCGGCACCTCGCG
GTGCGTCCCGACCGGGTGGT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MTKARMSRSAYAHMFGPTVGDKVRLADTALYIEIEKDFTVHGEEVKFGGGKVIRDGMGQSQVANADGAVDTVITNAVILD
HWGIVKADVGLKDGRIFKIGKAGNPDVQSGVDIIIGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGG
GTGPATGTFATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASQPKALEEMVRAGACALKLHEDWGTTPAAIDTCLSVAD
AFDIQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLPNVLPSSTNPTRPYTRNTIDEHLDMLM
VCHHLSPSIPEDLAFAESRIRKETIAAEDILHDIGALSMMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGESGGNDN
LRARRYVAKYTINPAIAHGVSKHIGSVEAGKLADLVLWSPAFFGVKPDLVLKGGSIAVAQMGDPNASIPTPQPVHYRPMF
GAYGRARTHSSLTFVSKAAVEDGLAARLQTAKTLVAVENVRSGISKKDMVLNGATPHIEVDPETYDVRADGELLVCEPAD
VLPMAQRYFLF

Sequences:

>Translated_571_residues
MTKARMSRSAYAHMFGPTVGDKVRLADTALYIEIEKDFTVHGEEVKFGGGKVIRDGMGQSQVANADGAVDTVITNAVILD
HWGIVKADVGLKDGRIFKIGKAGNPDVQSGVDIIIGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGG
GTGPATGTFATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASQPKALEEMVRAGACALKLHEDWGTTPAAIDTCLSVAD
AFDIQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLPNVLPSSTNPTRPYTRNTIDEHLDMLM
VCHHLSPSIPEDLAFAESRIRKETIAAEDILHDIGALSMMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGESGGNDN
LRARRYVAKYTINPAIAHGVSKHIGSVEAGKLADLVLWSPAFFGVKPDLVLKGGSIAVAQMGDPNASIPTPQPVHYRPMF
GAYGRARTHSSLTFVSKAAVEDGLAARLQTAKTLVAVENVRSGISKKDMVLNGATPHIEVDPETYDVRADGELLVCEPAD
VLPMAQRYFLF
>Mature_570_residues
TKARMSRSAYAHMFGPTVGDKVRLADTALYIEIEKDFTVHGEEVKFGGGKVIRDGMGQSQVANADGAVDTVITNAVILDH
WGIVKADVGLKDGRIFKIGKAGNPDVQSGVDIIIGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGGG
TGPATGTFATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASQPKALEEMVRAGACALKLHEDWGTTPAAIDTCLSVADA
FDIQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLPNVLPSSTNPTRPYTRNTIDEHLDMLMV
CHHLSPSIPEDLAFAESRIRKETIAAEDILHDIGALSMMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGESGGNDNL
RARRYVAKYTINPAIAHGVSKHIGSVEAGKLADLVLWSPAFFGVKPDLVLKGGSIAVAQMGDPNASIPTPQPVHYRPMFG
AYGRARTHSSLTFVSKAAVEDGLAARLQTAKTLVAVENVRSGISKKDMVLNGATPHIEVDPETYDVRADGELLVCEPADV
LPMAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 60690; Mature: 60559

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKARMSRSAYAHMFGPTVGDKVRLADTALYIEIEKDFTVHGEEVKFGGGKVIRDGMGQS
CCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEECCEEECCCEEEECCCEEEECCCCCC
QVANADGAVDTVITNAVILDHWGIVKADVGLKDGRIFKIGKAGNPDVQSGVDIIIGPGTE
CCCCCCCCHHHHHHCEEEEECCCEEEECCCCCCCCEEEECCCCCCCHHCCCEEEECCCCE
VIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGGGTGPATGTFATTCTPGPWHI
EEECCCEEEEECCCCCCEEEECHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCCCHHHH
ARMIEAADAFPMNLAFAGKGNASQPKALEEMVRAGACALKLHEDWGTTPAAIDTCLSVAD
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHC
AFDIQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLPNVLPSS
CEEEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCC
TNPTRPYTRNTIDEHLDMLMVCHHLSPSIPEDLAFAESRIRKETIAAEDILHDIGALSMM
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGESGGNDNLRARRYVAKYTINPAIAHGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEEEEECCHHHHHHH
SKHIGSVEAGKLADLVLWSPAFFGVKPDLVLKGGSIAVAQMGDPNASIPTPQPVHYRPMF
HHHHCCCCCCCHHEEEEECCHHCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCEECCCC
GAYGRARTHSSLTFVSKAAVEDGLAARLQTAKTLVAVENVRSGISKKDMVLNGATPHIEV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEE
DPETYDVRADGELLVCEPADVLPMAQRYFLF
CCCEEEEECCCCEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
TKARMSRSAYAHMFGPTVGDKVRLADTALYIEIEKDFTVHGEEVKFGGGKVIRDGMGQS
CHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEECCEEECCCEEEECCCEEEECCCCCC
QVANADGAVDTVITNAVILDHWGIVKADVGLKDGRIFKIGKAGNPDVQSGVDIIIGPGTE
CCCCCCCCHHHHHHCEEEEECCCEEEECCCCCCCCEEEECCCCCCCHHCCCEEEECCCCE
VIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGGGTGPATGTFATTCTPGPWHI
EEECCCEEEEECCCCCCEEEECHHHHHHHHHCCCHHHHCCCCCCCCCCEEECCCCCHHHH
ARMIEAADAFPMNLAFAGKGNASQPKALEEMVRAGACALKLHEDWGTTPAAIDTCLSVAD
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHC
AFDIQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLPNVLPSS
CEEEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCC
TNPTRPYTRNTIDEHLDMLMVCHHLSPSIPEDLAFAESRIRKETIAAEDILHDIGALSMM
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGESGGNDNLRARRYVAKYTINPAIAHGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEEEEECCHHHHHHH
SKHIGSVEAGKLADLVLWSPAFFGVKPDLVLKGGSIAVAQMGDPNASIPTPQPVHYRPMF
HHHHCCCCCCCHHEEEEECCHHCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCEECCCC
GAYGRARTHSSLTFVSKAAVEDGLAARLQTAKTLVAVENVRSGISKKDMVLNGATPHIEV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEE
DPETYDVRADGELLVCEPADVLPMAQRYFLF
CCCEEEEECCCCEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA