Click here to switch to the map view.

The map label for this gene is marC [C]

Identifier: 158423163

GI number: 158423163

Start: 1751422

End: 1752105

Strand: Reverse

Name: marC [C]

Synonym: AZC_1539

Alternate gene names: 158423163

Gene position: 1752105-1751422 (Counterclockwise)

Preceding gene: 158423164

Following gene: 158423161

Centisome position: 32.63

GC content: 66.08

Gene sequence:

>684_bases
TTGAGCCAGTTCATCAACATCTTCGTGGCGGTCTTCGCCGCCCTCTTTCCCATCGTGAACCCGCTCGGCGGCGCGCCCAT
CTTCTATGAGATGACCCGCGCCTGCGCGCCGCAGGTGCGCGCCTCGCTGGCGATGAAGGTGGCCATCTACGGCTTCATCC
TGCTGGTGGTTTCTCTGGTGGCGGGCTCGCGCATCCTCACCTTCTTCGGCATCAGCCTGCCGGTGCTGCGGGTGGCGGGC
GGGCTCGTCGTCACCTTCGTCGGCTGGAACATCCTGCATCAGGGAGACGCGAGCGCGGAGAAGGCGCCGGACGCCACCGC
AACGCGGGACGTGGACGTCCTGCGGGTGGAGCAGCAGGCATTCTATCCGCTCACCATGCCCCTTACGATGGGCCCCGGCT
CCATCGCCACCGCCATCGCGCTCGGCTCGCAGGGCACGTTCAATCCGGCGGACGGCTACGGCCATATGATCATCGAGGCC
ATGGGGGCGCTCTCGGGCATCGCGGCGGTCTCGGCCTCGGTCTATTTCGCCTATCGCTATGCCAGCGATATCGAGCGCTT
CCTCGGGCCCAACGGCACCAACGTGCTGGTGCGCCTGTTCGCCTTCATCCTGCTCTGCATCGGCATGCAGATCATGTGGC
TGGGCATCCGCGATCTCGTCGCAAGTCTGCCCGTCCACGGCTGA

Upstream 100 bases:

>100_bases
GCTTCCTGCCGCAGGAGCGTCTTTCGCCCCACGGCTGGGAGCGCGTGGACGAATAGTCGAAGGTCCTTCAAAACCTTAAA
GACCAAGGCCGGGGAGCGGC

Downstream 100 bases:

>100_bases
CCGGCGCCCGGTTCAGGCCTCGCCAGCTTCTGCCGCCGCGCGACCGAGCGGCGCCGCGAAGGTGAGGAGGTTCCAGGCCC
CTCTGCCGCCACGCAGTTCC

Product: multiple antibiotic resistance (MarC)-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSQFINIFVAVFAALFPIVNPLGGAPIFYEMTRACAPQVRASLAMKVAIYGFILLVVSLVAGSRILTFFGISLPVLRVAG
GLVVTFVGWNILHQGDASAEKAPDATATRDVDVLRVEQQAFYPLTMPLTMGPGSIATAIALGSQGTFNPADGYGHMIIEA
MGALSGIAAVSASVYFAYRYASDIERFLGPNGTNVLVRLFAFILLCIGMQIMWLGIRDLVASLPVHG

Sequences:

>Translated_227_residues
MSQFINIFVAVFAALFPIVNPLGGAPIFYEMTRACAPQVRASLAMKVAIYGFILLVVSLVAGSRILTFFGISLPVLRVAG
GLVVTFVGWNILHQGDASAEKAPDATATRDVDVLRVEQQAFYPLTMPLTMGPGSIATAIALGSQGTFNPADGYGHMIIEA
MGALSGIAAVSASVYFAYRYASDIERFLGPNGTNVLVRLFAFILLCIGMQIMWLGIRDLVASLPVHG
>Mature_226_residues
SQFINIFVAVFAALFPIVNPLGGAPIFYEMTRACAPQVRASLAMKVAIYGFILLVVSLVAGSRILTFFGISLPVLRVAGG
LVVTFVGWNILHQGDASAEKAPDATATRDVDVLRVEQQAFYPLTMPLTMGPGSIATAIALGSQGTFNPADGYGHMIIEAM
GALSGIAAVSASVYFAYRYASDIERFLGPNGTNVLVRLFAFILLCIGMQIMWLGIRDLVASLPVHG

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=203, Percent_Identity=27.5862068965517, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787494, Length=220, Percent_Identity=27.7272727272727, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789842, Length=216, Percent_Identity=25, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 24133; Mature: 24002

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFINIFVAVFAALFPIVNPLGGAPIFYEMTRACAPQVRASLAMKVAIYGFILLVVSLV
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSRILTFFGISLPVLRVAGGLVVTFVGWNILHQGDASAEKAPDATATRDVDVLRVEQQA
CCCHHHHHHHHHHHHHHHHCCHHEEEHHHHHHCCCCCCCCCCCCCCCCCCHHHEEEHHHH
FYPLTMPLTMGPGSIATAIALGSQGTFNPADGYGHMIIEAMGALSGIAAVSASVYFAYRY
CCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDIERFLGPNGTNVLVRLFAFILLCIGMQIMWLGIRDLVASLPVHG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQFINIFVAVFAALFPIVNPLGGAPIFYEMTRACAPQVRASLAMKVAIYGFILLVVSLV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSRILTFFGISLPVLRVAGGLVVTFVGWNILHQGDASAEKAPDATATRDVDVLRVEQQA
CCCHHHHHHHHHHHHHHHHCCHHEEEHHHHHHCCCCCCCCCCCCCCCCCCHHHEEEHHHH
FYPLTMPLTMGPGSIATAIALGSQGTFNPADGYGHMIIEAMGALSGIAAVSASVYFAYRY
CCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASDIERFLGPNGTNVLVRLFAFILLCIGMQIMWLGIRDLVASLPVHG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]