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The map label for this gene is lysR [C]

Identifier: 158423033

GI number: 158423033

Start: 1604111

End: 1605025

Strand: Reverse

Name: lysR [C]

Synonym: AZC_1409

Alternate gene names: 158423033

Gene position: 1605025-1604111 (Counterclockwise)

Preceding gene: 158423045

Following gene: 158423031

Centisome position: 29.89

GC content: 67.32

Gene sequence:

>915_bases
ATGGATCGCCTGGCCCAGATCGAGGTCTTCCTGAAGACGGCCGAATTGCGCAGCCTCTCCCGCGCGGCCGAGGCGCTGGG
TATGTCGAACGCCGCCGTGAGCCGCCATCTCTCGGCGCTGGAGGAGCGCCTGTCCGCCCGGCTCGTCGAGCGCAACACGC
GCCGCCTCTGGCTCACGGAAGCCGGACAGGAATTCTACCAGCGCAGCGGCGCGCTCCTTGCCGAGCTCGCCGAGGCGGAG
GAGGCCGTCAATGAGCACACGCTTTCTCCGCAGGGATTGTTGCGTGTGACGAGTTCTTTGTCCTTCGCCACCATCTATCT
GGCGCCCATGCTCCCGGAGCTGCGCCGGCTCTATCCCAAGCTCAGCGTGCACATCGCGGTGGCGAACCGCTATCTCGACT
TCATCGAAGCGGGGATCGATGTCGCCATCCGCACCCGCCTGCACGAGCCGGACACCAACATCGTGGTGCGGCGGCTCGGG
CGCATGCGCCGGGTGCTGGCCGCCTCCCCCGCCTATCTGGAGGAACGCGGCCGGCCGAAGGAGCCCGCCGACCTCGCCCG
GCATGACATGCTGGTCTACAATCTGGCGCAGGATCCCTTCTCCCTGCGCCTCTCCAAGGGCGAGGCAGAGCGCACCGTCC
GCATCACCGCGGCGCTCGATTGCAATGACGGGCAGGTGATCCGGCAGGCGGCCATCGCCGGGCTCGGCATTCTCGTCCAG
CCCCTCTACATCGTGCAGGAGGATCTCGAGGCCGGGCGGCTGGTGCCGGTGCTGCTGGACTGGCAACTGCCCATGCTGAC
CATGAACATTGCCTACCAGAACCGCGAGCGTCTGCCGGCCAAGATCCGCGTCTTCACGGACTTCCTGGTCAATTACGTGC
GGCGGACCTCGGACGGCGGCATCTGGTCCGCGTGA

Upstream 100 bases:

>100_bases
TTCCTCGACCTTATTGGTCTTTGATTGCTTGCAGTTTTGACTTGCACGCGGTGGAAATAAACCGGAATTTTCGGAACGGT
CTTTTGCGCGGAGCGGAAAG

Downstream 100 bases:

>100_bases
GCGCACCGACGCGACCCGTCAGCAGAAATCGAAATCGCACCCCTCGTCCGCCTGAAGGACGTGGGTAAGATAAAGGTGCT
GATAGCCGCGCGCCGCCTCG

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDRLAQIEVFLKTAELRSLSRAAEALGMSNAAVSRHLSALEERLSARLVERNTRRLWLTEAGQEFYQRSGALLAELAEAE
EAVNEHTLSPQGLLRVTSSLSFATIYLAPMLPELRRLYPKLSVHIAVANRYLDFIEAGIDVAIRTRLHEPDTNIVVRRLG
RMRRVLAASPAYLEERGRPKEPADLARHDMLVYNLAQDPFSLRLSKGEAERTVRITAALDCNDGQVIRQAAIAGLGILVQ
PLYIVQEDLEAGRLVPVLLDWQLPMLTMNIAYQNRERLPAKIRVFTDFLVNYVRRTSDGGIWSA

Sequences:

>Translated_304_residues
MDRLAQIEVFLKTAELRSLSRAAEALGMSNAAVSRHLSALEERLSARLVERNTRRLWLTEAGQEFYQRSGALLAELAEAE
EAVNEHTLSPQGLLRVTSSLSFATIYLAPMLPELRRLYPKLSVHIAVANRYLDFIEAGIDVAIRTRLHEPDTNIVVRRLG
RMRRVLAASPAYLEERGRPKEPADLARHDMLVYNLAQDPFSLRLSKGEAERTVRITAALDCNDGQVIRQAAIAGLGILVQ
PLYIVQEDLEAGRLVPVLLDWQLPMLTMNIAYQNRERLPAKIRVFTDFLVNYVRRTSDGGIWSA
>Mature_304_residues
MDRLAQIEVFLKTAELRSLSRAAEALGMSNAAVSRHLSALEERLSARLVERNTRRLWLTEAGQEFYQRSGALLAELAEAE
EAVNEHTLSPQGLLRVTSSLSFATIYLAPMLPELRRLYPKLSVHIAVANRYLDFIEAGIDVAIRTRLHEPDTNIVVRRLG
RMRRVLAASPAYLEERGRPKEPADLARHDMLVYNLAQDPFSLRLSKGEAERTVRITAALDCNDGQVIRQAAIAGLGILVQ
PLYIVQEDLEAGRLVPVLLDWQLPMLTMNIAYQNRERLPAKIRVFTDFLVNYVRRTSDGGIWSA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=31.6666666666667, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1786401, Length=305, Percent_Identity=30.8196721311475, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=30.8219178082192, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=32.7645051194539, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=31.0344827586207, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=29.616724738676, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=26.1168384879725, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789173, Length=253, Percent_Identity=31.2252964426877, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788706, Length=141, Percent_Identity=32.6241134751773, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI157672245, Length=120, Percent_Identity=30.8333333333333, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082132, Length=271, Percent_Identity=23.9852398523985, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790011, Length=291, Percent_Identity=22.3367697594502, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34237; Mature: 34237

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLAQIEVFLKTAELRSLSRAAEALGMSNAAVSRHLSALEERLSARLVERNTRRLWLTE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEH
AGQEFYQRSGALLAELAEAEEAVNEHTLSPQGLLRVTSSLSFATIYLAPMLPELRRLYPK
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LSVHIAVANRYLDFIEAGIDVAIRTRLHEPDTNIVVRRLGRMRRVLAASPAYLEERGRPK
HEEEEHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
EPADLARHDMLVYNLAQDPFSLRLSKGEAERTVRITAALDCNDGQVIRQAAIAGLGILVQ
CCHHHHHHHHHEEEECCCCCEEEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHH
PLYIVQEDLEAGRLVPVLLDWQLPMLTMNIAYQNRERLPAKIRVFTDFLVNYVRRTSDGG
HHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCC
IWSA
CCCC
>Mature Secondary Structure
MDRLAQIEVFLKTAELRSLSRAAEALGMSNAAVSRHLSALEERLSARLVERNTRRLWLTE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEH
AGQEFYQRSGALLAELAEAEEAVNEHTLSPQGLLRVTSSLSFATIYLAPMLPELRRLYPK
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LSVHIAVANRYLDFIEAGIDVAIRTRLHEPDTNIVVRRLGRMRRVLAASPAYLEERGRPK
HEEEEHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
EPADLARHDMLVYNLAQDPFSLRLSKGEAERTVRITAALDCNDGQVIRQAAIAGLGILVQ
CCHHHHHHHHHEEEECCCCCEEEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHH
PLYIVQEDLEAGRLVPVLLDWQLPMLTMNIAYQNRERLPAKIRVFTDFLVNYVRRTSDGG
HHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCC
IWSA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]