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The map label for this gene is zraS [C]

Identifier: 158423045

GI number: 158423045

Start: 1616332

End: 1618869

Strand: Reverse

Name: zraS [C]

Synonym: AZC_1421

Alternate gene names: 158423045

Gene position: 1618869-1616332 (Counterclockwise)

Preceding gene: 158423047

Following gene: 158423033

Centisome position: 30.15

GC content: 66.27

Gene sequence:

>2538_bases
TTGACCGGCTCTGCGTTGTTCATCCTTGAGCCTGGCAGCAATGCCGAACAGTCGTTCATCTTGGGGGGCCGCGTGGGAAG
ATCGACGCCAGATCTGGACGATATTTTCCCCGGTGACAGCGCCATGGCCAAGCTCATGCGCCAGCATGACTGGTCCGCGA
CGCCGCTCGGCTGCCCGAGCACGTGGCCGGACGGGCTGACCATCCCTCTGCGCATGCTGCTCACCTCGCGCTTCGAGATG
TGGCTCGGCTGGGGCGAGGATCTGCGTTTCTTCTACAACGATGCCTACATCCCGACGCTCGGCATCAAGCACCCCAGCAT
GCTGGGGCGGCCGTTCCGCGAGGTGTGGGCCGAGGTCTATGACGACGTGGCCGATCAGGTGGCCAAGGTCCGCGCCGGTG
AGGCCACCTGGAACGACAGCCTGATGCTCATCCTGGAGCGCAGCGGCTATCCAGAGGAGACCTACCACAGCTTCTCCTAC
AGCCCGCTCTATGGAGCAGAACGGGCGGTAGAGGGCCTGCTATGCATCGTGACCGAGGTCACGCGGCCAGTCATCAGCGA
CCGCCGGCTCAGCACGTTGCGGCAGCTCGGTACGGCATTGGTAGGTGTGACCTCGCGGGACGAAGTGAGCCTTGCGGTCT
GTGCCGTGCTCGGCGCCAACCGGCGGGACTTTCCCTTCGCCCTTCTGTTCCTCGGCGACGGGAGCACACGGCAGGCCGTC
GCCTGCTCTGCGGATGCGGCCCATCTGCTGAACGGGCCATGGCCGGATGATCCGCCAGCGAACGGCATCAGCTTCGCCCT
GCCGCCAGACGTGGATTATCCCGCCGGCGACTGGCCCGCGCGGCCGCGCGAGGCCCTGTCCGTGCCCATTCCCGGCGCCG
CCGGCCGGCCCGCCGCCGGCTTTCTCATCCTCGGCCTCAATCCCTTTCGCCAGCGCGGCGAAAATGTCGCCGATCTCGCC
AATCTCCTCGCCGGCCAGATCAGCGGCGCCCTCGCCAATGTGGCGACGCTGGCCACCGAGCGCCGCCGGGCCGATCGCAT
CTGGACCAACTCCCGCGATCTTCTGGTGACGGTGGACGCAGCGGGCGTCTTCCAGTCCGTCAGCCCGTCCTGGACCCGCA
TCCTCAAGCACCCCATCGAAGCCGTGGTCGGCCGGAGCTTTTCCGATTTCATCCACCCCGACGATCTGGAGCCGGCGCAT
CAGGCGCTCCGCAAGGCCATGTCGGGCTCCTATCTGACGGGCCTCGAGAACCGCTTCCAGACGGCGGACGGCGAGGTGCG
CCACATCTCGTGGAACACTGCCATGGAGGATGGCCTCGTCTATGGCTATGGGCGTGACGTCACCGAGGAGAAGGCCAAGG
CCGCCGCACTCGCCAATGCGGAGGAAGCGTTGCGCCATGCCCAGAAGATGGAGGCAGTAGGACAGCTCACCGGCGGCATC
GCGCATGATTTCAACAATCTGCTGACTGGCATCATCGGCTCGCTGGATCTGGTGCGCCGGAGGATCAAGCCCGACTGGCC
GTCGGATGTGGACCGCTTCCTGACCGTCGCCACGAGTTCGGCGGAGCGTGCGGCCTCGCTCACACAGCGCCTGCTCGCCT
TCGCCCGCCGGCAGTCGCTCGATCCGCAGCCGGTACAGGCGCACCAGCTGGTGGTGGGCATGCTGGACCTCATCAAGAAG
TCCATCGGCGAACTGATCGTGCTGCGCATCGAGACCGAGGAGGATCTCTGGAACGCCCGCTGCGATCCCAACCAGTTGGA
GAGTTCGGTCCTCAATCTCGCGATCAACTCGCGGGATGCCATGCCGGACGGCGGAACGCTCACCATCCGGACGGAAAATG
TCCGGGTCGAGCCCGCCGATCTCGGGCGCGTGGCGCTCCCGGCGCCGGGGGACTATGTGCTGCTCCAGGTCGAGGACACG
GGGCACGGCATGCCGGCCCATGTCATCTCGAAGGCCTTCGAGCCCTTCTTCACCACCAAGCCGCTCGGCAAGGGCACGGG
CCTCGGCCTCTCCATGATCTACGGCTTTGCCCAGCAGTCCGGCGGTACCGTCCTTATCGAGAGCGTGGAGCAGCAAGGCA
CGGTGGTCTCGCTGTATATCCCCCGCTCGCGGGAAGATGCCCGGCCCATCGTGCCCGCCGGGGGCGATGCCGATCGCGCG
GAAGCGATCAAGCACGCGGCGACCATCCTGATCGTCGAGGACGAGCCTGCGGTCCGGCTGCTGGTCACGGAATCACTTGG
CGCGCTCGGCTATGAGACGCTGGTGGCCTCTACCGGGCCCGATGGCCTCAGGATCCTCCAGTCCGACCAGCCCATCGACC
TGCTGCTGACGGACGTGGGATTGCCCGGCCTCAACGGACGCCAGCTTGCGGACGCCGCCCGCGTCACCCGCCCCAATCTG
AAAGTCCTGTTCGTGACCGGATATGTGCACGATTCCGGCCTGTACGAGGATGGTCTGGAACCGGGCATGGCGGTCGTCAC
CAAGCCGTTCGACATCGATAAGCTTGCCAAACGGGTCGCGGAGCTCATCGGGCAATGA

Upstream 100 bases:

>100_bases
CGGCCCCGCGCATCTGTGTTCTGCGGTCCACATCCTGCGCCTCCGAAAGGCATCGACCGGACGCTTCGGCACTTCTAAGA
TCGCGCGATAACAGAACCTC

Downstream 100 bases:

>100_bases
GGCTCCGCATCCGCGTTTGAGCGACGGCCTCAGCCCTGACGGCGGATGAAGCCGGTGATGGTGACGCGAGCCCAGATGCC
CGCCTTCTTGAACGGGTCGG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 845; Mature: 844

Protein sequence:

>845_residues
MTGSALFILEPGSNAEQSFILGGRVGRSTPDLDDIFPGDSAMAKLMRQHDWSATPLGCPSTWPDGLTIPLRMLLTSRFEM
WLGWGEDLRFFYNDAYIPTLGIKHPSMLGRPFREVWAEVYDDVADQVAKVRAGEATWNDSLMLILERSGYPEETYHSFSY
SPLYGAERAVEGLLCIVTEVTRPVISDRRLSTLRQLGTALVGVTSRDEVSLAVCAVLGANRRDFPFALLFLGDGSTRQAV
ACSADAAHLLNGPWPDDPPANGISFALPPDVDYPAGDWPARPREALSVPIPGAAGRPAAGFLILGLNPFRQRGENVADLA
NLLAGQISGALANVATLATERRRADRIWTNSRDLLVTVDAAGVFQSVSPSWTRILKHPIEAVVGRSFSDFIHPDDLEPAH
QALRKAMSGSYLTGLENRFQTADGEVRHISWNTAMEDGLVYGYGRDVTEEKAKAAALANAEEALRHAQKMEAVGQLTGGI
AHDFNNLLTGIIGSLDLVRRRIKPDWPSDVDRFLTVATSSAERAASLTQRLLAFARRQSLDPQPVQAHQLVVGMLDLIKK
SIGELIVLRIETEEDLWNARCDPNQLESSVLNLAINSRDAMPDGGTLTIRTENVRVEPADLGRVALPAPGDYVLLQVEDT
GHGMPAHVISKAFEPFFTTKPLGKGTGLGLSMIYGFAQQSGGTVLIESVEQQGTVVSLYIPRSREDARPIVPAGGDADRA
EAIKHAATILIVEDEPAVRLLVTESLGALGYETLVASTGPDGLRILQSDQPIDLLLTDVGLPGLNGRQLADAARVTRPNL
KVLFVTGYVHDSGLYEDGLEPGMAVVTKPFDIDKLAKRVAELIGQ

Sequences:

>Translated_845_residues
MTGSALFILEPGSNAEQSFILGGRVGRSTPDLDDIFPGDSAMAKLMRQHDWSATPLGCPSTWPDGLTIPLRMLLTSRFEM
WLGWGEDLRFFYNDAYIPTLGIKHPSMLGRPFREVWAEVYDDVADQVAKVRAGEATWNDSLMLILERSGYPEETYHSFSY
SPLYGAERAVEGLLCIVTEVTRPVISDRRLSTLRQLGTALVGVTSRDEVSLAVCAVLGANRRDFPFALLFLGDGSTRQAV
ACSADAAHLLNGPWPDDPPANGISFALPPDVDYPAGDWPARPREALSVPIPGAAGRPAAGFLILGLNPFRQRGENVADLA
NLLAGQISGALANVATLATERRRADRIWTNSRDLLVTVDAAGVFQSVSPSWTRILKHPIEAVVGRSFSDFIHPDDLEPAH
QALRKAMSGSYLTGLENRFQTADGEVRHISWNTAMEDGLVYGYGRDVTEEKAKAAALANAEEALRHAQKMEAVGQLTGGI
AHDFNNLLTGIIGSLDLVRRRIKPDWPSDVDRFLTVATSSAERAASLTQRLLAFARRQSLDPQPVQAHQLVVGMLDLIKK
SIGELIVLRIETEEDLWNARCDPNQLESSVLNLAINSRDAMPDGGTLTIRTENVRVEPADLGRVALPAPGDYVLLQVEDT
GHGMPAHVISKAFEPFFTTKPLGKGTGLGLSMIYGFAQQSGGTVLIESVEQQGTVVSLYIPRSREDARPIVPAGGDADRA
EAIKHAATILIVEDEPAVRLLVTESLGALGYETLVASTGPDGLRILQSDQPIDLLLTDVGLPGLNGRQLADAARVTRPNL
KVLFVTGYVHDSGLYEDGLEPGMAVVTKPFDIDKLAKRVAELIGQ
>Mature_844_residues
TGSALFILEPGSNAEQSFILGGRVGRSTPDLDDIFPGDSAMAKLMRQHDWSATPLGCPSTWPDGLTIPLRMLLTSRFEMW
LGWGEDLRFFYNDAYIPTLGIKHPSMLGRPFREVWAEVYDDVADQVAKVRAGEATWNDSLMLILERSGYPEETYHSFSYS
PLYGAERAVEGLLCIVTEVTRPVISDRRLSTLRQLGTALVGVTSRDEVSLAVCAVLGANRRDFPFALLFLGDGSTRQAVA
CSADAAHLLNGPWPDDPPANGISFALPPDVDYPAGDWPARPREALSVPIPGAAGRPAAGFLILGLNPFRQRGENVADLAN
LLAGQISGALANVATLATERRRADRIWTNSRDLLVTVDAAGVFQSVSPSWTRILKHPIEAVVGRSFSDFIHPDDLEPAHQ
ALRKAMSGSYLTGLENRFQTADGEVRHISWNTAMEDGLVYGYGRDVTEEKAKAAALANAEEALRHAQKMEAVGQLTGGIA
HDFNNLLTGIIGSLDLVRRRIKPDWPSDVDRFLTVATSSAERAASLTQRLLAFARRQSLDPQPVQAHQLVVGMLDLIKKS
IGELIVLRIETEEDLWNARCDPNQLESSVLNLAINSRDAMPDGGTLTIRTENVRVEPADLGRVALPAPGDYVLLQVEDTG
HGMPAHVISKAFEPFFTTKPLGKGTGLGLSMIYGFAQQSGGTVLIESVEQQGTVVSLYIPRSREDARPIVPAGGDADRAE
AIKHAATILIVEDEPAVRLLVTESLGALGYETLVASTGPDGLRILQSDQPIDLLLTDVGLPGLNGRQLADAARVTRPNLK
VLFVTGYVHDSGLYEDGLEPGMAVVTKPFDIDKLAKRVAELIGQ

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=26.4462809917355, Blast_Score=93, Evalue=8e-20,
Organism=Escherichia coli, GI1788549, Length=393, Percent_Identity=26.2086513994911, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI87081816, Length=381, Percent_Identity=22.5721784776903, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=297, Percent_Identity=25.2525252525253, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=243, Percent_Identity=28.8065843621399, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI48994928, Length=501, Percent_Identity=24.1516966067864, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=253, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91542; Mature: 91411

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSALFILEPGSNAEQSFILGGRVGRSTPDLDDIFPGDSAMAKLMRQHDWSATPLGCPS
CCCCEEEEECCCCCCCCEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
TWPDGLTIPLRMLLTSRFEMWLGWGEDLRFFYNDAYIPTLGIKHPSMLGRPFREVWAEVY
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCEECCCCHHHHCCHHHHHHHHHH
DDVADQVAKVRAGEATWNDSLMLILERSGYPEETYHSFSYSPLYGAERAVEGLLCIVTEV
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TRPVISDRRLSTLRQLGTALVGVTSRDEVSLAVCAVLGANRRDFPFALLFLGDGSTRQAV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEE
ACSADAAHLLNGPWPDDPPANGISFALPPDVDYPAGDWPARPREALSVPIPGAAGRPAAG
EECCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHEECCCCCCCCCCCCC
FLILGLNPFRQRGENVADLANLLAGQISGALANVATLATERRRADRIWTNSRDLLVTVDA
EEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
AGVFQSVSPSWTRILKHPIEAVVGRSFSDFIHPDDLEPAHQALRKAMSGSYLTGLENRFQ
CHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHC
TADGEVRHISWNTAMEDGLVYGYGRDVTEEKAKAAALANAEEALRHAQKMEAVGQLTGGI
CCCCCEEEEEECCHHHCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHH
AHDFNNLLTGIIGSLDLVRRRIKPDWPSDVDRFLTVATSSAERAASLTQRLLAFARRQSL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
DPQPVQAHQLVVGMLDLIKKSIGELIVLRIETEEDLWNARCDPNQLESSVLNLAINSRDA
CCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHCCCCCHHHHHHHHHHHEECCCCC
MPDGGTLTIRTENVRVEPADLGRVALPAPGDYVLLQVEDTGHGMPAHVISKAFEPFFTTK
CCCCCEEEEEECCEEECHHCCCEEECCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCC
PLGKGTGLGLSMIYGFAQQSGGTVLIESVEQQGTVVSLYIPRSREDARPIVPAGGDADRA
CCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCHHHH
EAIKHAATILIVEDEPAVRLLVTESLGALGYETLVASTGPDGLRILQSDQPIDLLLTDVG
HHHHHHEEEEEECCCCCEEEEEEHHCCCCCHHHHEECCCCCCEEEECCCCCCEEEEEECC
LPGLNGRQLADAARVTRPNLKVLFVTGYVHDSGLYEDGLEPGMAVVTKPFDIDKLAKRVA
CCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHH
ELIGQ
HHHCC
>Mature Secondary Structure 
TGSALFILEPGSNAEQSFILGGRVGRSTPDLDDIFPGDSAMAKLMRQHDWSATPLGCPS
CCCEEEEECCCCCCCCEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCC
TWPDGLTIPLRMLLTSRFEMWLGWGEDLRFFYNDAYIPTLGIKHPSMLGRPFREVWAEVY
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCEECCCCHHHHCCHHHHHHHHHH
DDVADQVAKVRAGEATWNDSLMLILERSGYPEETYHSFSYSPLYGAERAVEGLLCIVTEV
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TRPVISDRRLSTLRQLGTALVGVTSRDEVSLAVCAVLGANRRDFPFALLFLGDGSTRQAV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEE
ACSADAAHLLNGPWPDDPPANGISFALPPDVDYPAGDWPARPREALSVPIPGAAGRPAAG
EECCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHEECCCCCCCCCCCCC
FLILGLNPFRQRGENVADLANLLAGQISGALANVATLATERRRADRIWTNSRDLLVTVDA
EEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
AGVFQSVSPSWTRILKHPIEAVVGRSFSDFIHPDDLEPAHQALRKAMSGSYLTGLENRFQ
CHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHC
TADGEVRHISWNTAMEDGLVYGYGRDVTEEKAKAAALANAEEALRHAQKMEAVGQLTGGI
CCCCCEEEEEECCHHHCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHH
AHDFNNLLTGIIGSLDLVRRRIKPDWPSDVDRFLTVATSSAERAASLTQRLLAFARRQSL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
DPQPVQAHQLVVGMLDLIKKSIGELIVLRIETEEDLWNARCDPNQLESSVLNLAINSRDA
CCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHCCCCCHHHHHHHHHHHEECCCCC
MPDGGTLTIRTENVRVEPADLGRVALPAPGDYVLLQVEDTGHGMPAHVISKAFEPFFTTK
CCCCCEEEEEECCEEECHHCCCEEECCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCC
PLGKGTGLGLSMIYGFAQQSGGTVLIESVEQQGTVVSLYIPRSREDARPIVPAGGDADRA
CCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCHHHH
EAIKHAATILIVEDEPAVRLLVTESLGALGYETLVASTGPDGLRILQSDQPIDLLLTDVG
HHHHHHEEEEEECCCCCEEEEEEHHCCCCCHHHHEECCCCCCEEEECCCCCCEEEEEECC
LPGLNGRQLADAARVTRPNLKVLFVTGYVHDSGLYEDGLEPGMAVVTKPFDIDKLAKRVA
CCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHH
ELIGQ
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA