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The map label for this gene is lptA [H]

Identifier: 157963428

GI number: 157963428

Start: 4405734

End: 4406273

Strand: Direct

Name: lptA [H]

Synonym: Spea_3614

Alternate gene names: 157963428

Gene position: 4405734-4406273 (Clockwise)

Preceding gene: 157963427

Following gene: 157963429

Centisome position: 85.14

GC content: 46.48

Gene sequence:

>540_bases
ATGAAATACAATAAATCTATCCTTGCTGGCCTTTTTTGCCTGCTAAGTTTCAGCTCTACAGCTAAAGTCGATGATCTACT
GCAAGAAGTGAAAATTGCAGCGGCAAGCCAAGAAGCCGACATTAAGAATAATCAGGTTATCTTTTTTGGGCCTGTTGAAG
TGACTCAGGGCTCTATTAAGATGAATGCCGATGAGCTACGTGTATTTTCAAAAGAAGATAAGAGCGGTAAAACGCTAGTG
GCTACAGGTAATCCAGCCACCTACACCCAAATGATGGAAGATGGTCGCCCAGCGACCGCTAGCGCGAAAGAGATCCGCTA
CGAACTTGCGACTCGCACATTGACCTTAGTCGGTGAAGCGACCCTAGCGCAAGACGGCAGCCAAGTCACTGGTAACCGCA
TTAAGTACAACATTAGTCTACAACAGCTTATTGCTGAAAGTACTGGCAAGGGCGATGACAGAGTCATCACCATTATTCAG
CCTGAAACCTACCAGGAAGAGAAGCCTGACACGCCAGTGAACAAGCAGGAACAGCAATGA

Upstream 100 bases:

>100_bases
CAAGTCGAAGGCATCTACGAAGCTAAGTAACACTCATAAATTGAACACTTTTGCACTCATGCTAACTAAGCGAATCGCTT
TAGCTGAGTAGAAGGACGCT

Downstream 100 bases:

>100_bases
CCCAAATTACCTTAAAAGCGGCTAATCTTGCTAAAAGCTATAAAAACCGTGCCGTCGTACAAGATGTCAGTCTCACCGTA
AAAACGGGGCAAATTGTGGG

Product: cell envelope biogenesis YhbN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKYNKSILAGLFCLLSFSSTAKVDDLLQEVKIAAASQEADIKNNQVIFFGPVEVTQGSIKMNADELRVFSKEDKSGKTLV
ATGNPATYTQMMEDGRPATASAKEIRYELATRTLTLVGEATLAQDGSQVTGNRIKYNISLQQLIAESTGKGDDRVITIIQ
PETYQEEKPDTPVNKQEQQ

Sequences:

>Translated_179_residues
MKYNKSILAGLFCLLSFSSTAKVDDLLQEVKIAAASQEADIKNNQVIFFGPVEVTQGSIKMNADELRVFSKEDKSGKTLV
ATGNPATYTQMMEDGRPATASAKEIRYELATRTLTLVGEATLAQDGSQVTGNRIKYNISLQQLIAESTGKGDDRVITIIQ
PETYQEEKPDTPVNKQEQQ
>Mature_179_residues
MKYNKSILAGLFCLLSFSSTAKVDDLLQEVKIAAASQEADIKNNQVIFFGPVEVTQGSIKMNADELRVFSKEDKSGKTLV
ATGNPATYTQMMEDGRPATASAKEIRYELATRTLTLVGEATLAQDGSQVTGNRIKYNISLQQLIAESTGKGDDRVITIIQ
PETYQEEKPDTPVNKQEQQ

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=173, Percent_Identity=35.8381502890173, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 19637; Mature: 19637

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYNKSILAGLFCLLSFSSTAKVDDLLQEVKIAAASQEADIKNNQVIFFGPVEVTQGSIK
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEECCCEE
MNADELRVFSKEDKSGKTLVATGNPATYTQMMEDGRPATASAKEIRYELATRTLTLVGEA
ECHHHHEEECCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEEECH
TLAQDGSQVTGNRIKYNISLQQLIAESTGKGDDRVITIIQPETYQEEKPDTPVNKQEQQ
HHHCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKYNKSILAGLFCLLSFSSTAKVDDLLQEVKIAAASQEADIKNNQVIFFGPVEVTQGSIK
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEECCCEE
MNADELRVFSKEDKSGKTLVATGNPATYTQMMEDGRPATASAKEIRYELATRTLTLVGEA
ECHHHHEEECCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEEECH
TLAQDGSQVTGNRIKYNISLQQLIAESTGKGDDRVITIIQPETYQEEKPDTPVNKQEQQ
HHHCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]