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The map label for this gene is pqqL [C]

Identifier: 157963259

GI number: 157963259

Start: 4210948

End: 4212420

Strand: Direct

Name: pqqL [C]

Synonym: Spea_3445

Alternate gene names: 157963259

Gene position: 4210948-4212420 (Clockwise)

Preceding gene: 157963258

Following gene: 157963260

Centisome position: 81.38

GC content: 50.03

Gene sequence:

>1473_bases
TTGAAACGATTAATATTCATCAACAAAGCGAAAAACTATATCACCACAGTGACTGTGGCAGCCCTGTCGACATTGGCGAT
CAGTTTACCTGTTAGTGCGCTAACCAAAACTGAGCCTGCTGCCTGCAATCTAAATAAACTCGCTCAGCCCCTCTACGAAG
TTGAGCAGAGAATTCAATATCGTCAGCTGGATAATGGTCTGCAAGTGCGCACCCTGCCCCTTAAAAATACTCAAGCCGTG
TCAATCGCTAGCCAGTTTGATGTGGGCTCGCGCAATGAAGTTAAGGGTCAAGCCGGTTATGCCCACCTGTTTGAACACAT
GCTGTTTAAAGGCAGTAAGCATGCACCGGGTGATAGCTATACCCAGACCATGAGCGCCTTAAGCGGCCAGTTTAATGCCA
GCACCTTTTTCGATTTCACCAATTATTACTTAACCATCCCCTCCCAAGCACTCGAACTGAGCCTATGGCTAGAAGCCGAC
CGCTTTCGCTACCCAAGCTTGAATGAAACCACAGTTAAAAATCAACAAGGCGCGGTGCTTGAAGAGATGGCCACCAGCAT
AGATAACCAGCCCTATGTGCGCAAAGCGATGGAGTTTTTATTGTCTCAGGTTGAAGGGACGCCCTATGGTCATGCGGTTA
TCGGCAGTGTGGCTGATGTCAAAGCTGCCACACCACAAAGCTTAAATGCGTTTCATCAACGCTATTACCGCCCCGACGCC
ATGCAGCTAAGTTTAGTGGGCGATATCCCTAAGCAGACTCAGGATTGGATAGATGCGCAGTTTAGCGATTGGCAGGCGCC
TGATATCGAGCTGACTCAAATGGATGATCTTAAGGTTTCGCCAAAGCCAGTATATGGCGAAATCGTCGACGAGCGTGGCC
CTTGGCCTGCGGTGCTATTTGCTTGGCACACAGTTGGCTCAAACTCAAAAGATGCCGCGGGCCTTGCACTGCTGGAAGCT
TATCTGTTTCAAAACAAGAGCAGTCTAATTCAAGGTACTAGCCTTAGCGATCCCGACCAACTGCTGAGTTACTCGATCCC
GTTGACCATGACCCATCACGGCATGACCAATCTGGTACTCGTGCCCCGCGCCCGCACCTCCCTCGATAAGCTCAGTAAGA
ATGTCGAGTCACTGATAGCCTCTGTCGCCGCGCAGACCCTAGATGATGCACACCTATGCCAGTTAAAACAAATTTGGCTC
AATAAGGCGTTATCCACTTTAGACTCCCCCTCTCGGCTAGCGAGAAGCCTTTCGGCAACTCAACCCCGAGATAAACTCCA
TCCGCTTACCGGGCCATGGCAACGTATCGATGCCGTTAGCGCTAAAGAGCTTCAAGCCATCGCCCAGAGGTACTTTATCG
GCAATACCGTGCGGCTGGATCTGCTGCCCCCTTGGTATATTCGCGCCACTAAATCGATTCTTGAGTTGTTACCTAAAGAG
ATGAGCGATAGCCTTGAAGAGAGTGTAATGTGA

Upstream 100 bases:

>100_bases
GCAACCGCAAGGGCACTCGATGTCGACTCGGGCAACCTACACCGCCTAGCAAAGCGCATCGGCATAAAATAACTCGGACG
TTAAAGAGGGTTAAAAGGAA

Downstream 100 bases:

>100_bases
TGCAATCAATTAAAAATCTTAGCTTTTTAGCACTAGCTTGTAGTCTCATTATCAGTGCGCTTGGTTGCCAGCAGACTCAG
ATAGCCTTTACGCCAAAAGC

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MKRLIFINKAKNYITTVTVAALSTLAISLPVSALTKTEPAACNLNKLAQPLYEVEQRIQYRQLDNGLQVRTLPLKNTQAV
SIASQFDVGSRNEVKGQAGYAHLFEHMLFKGSKHAPGDSYTQTMSALSGQFNASTFFDFTNYYLTIPSQALELSLWLEAD
RFRYPSLNETTVKNQQGAVLEEMATSIDNQPYVRKAMEFLLSQVEGTPYGHAVIGSVADVKAATPQSLNAFHQRYYRPDA
MQLSLVGDIPKQTQDWIDAQFSDWQAPDIELTQMDDLKVSPKPVYGEIVDERGPWPAVLFAWHTVGSNSKDAAGLALLEA
YLFQNKSSLIQGTSLSDPDQLLSYSIPLTMTHHGMTNLVLVPRARTSLDKLSKNVESLIASVAAQTLDDAHLCQLKQIWL
NKALSTLDSPSRLARSLSATQPRDKLHPLTGPWQRIDAVSAKELQAIAQRYFIGNTVRLDLLPPWYIRATKSILELLPKE
MSDSLEESVM

Sequences:

>Translated_490_residues
MKRLIFINKAKNYITTVTVAALSTLAISLPVSALTKTEPAACNLNKLAQPLYEVEQRIQYRQLDNGLQVRTLPLKNTQAV
SIASQFDVGSRNEVKGQAGYAHLFEHMLFKGSKHAPGDSYTQTMSALSGQFNASTFFDFTNYYLTIPSQALELSLWLEAD
RFRYPSLNETTVKNQQGAVLEEMATSIDNQPYVRKAMEFLLSQVEGTPYGHAVIGSVADVKAATPQSLNAFHQRYYRPDA
MQLSLVGDIPKQTQDWIDAQFSDWQAPDIELTQMDDLKVSPKPVYGEIVDERGPWPAVLFAWHTVGSNSKDAAGLALLEA
YLFQNKSSLIQGTSLSDPDQLLSYSIPLTMTHHGMTNLVLVPRARTSLDKLSKNVESLIASVAAQTLDDAHLCQLKQIWL
NKALSTLDSPSRLARSLSATQPRDKLHPLTGPWQRIDAVSAKELQAIAQRYFIGNTVRLDLLPPWYIRATKSILELLPKE
MSDSLEESVM
>Mature_490_residues
MKRLIFINKAKNYITTVTVAALSTLAISLPVSALTKTEPAACNLNKLAQPLYEVEQRIQYRQLDNGLQVRTLPLKNTQAV
SIASQFDVGSRNEVKGQAGYAHLFEHMLFKGSKHAPGDSYTQTMSALSGQFNASTFFDFTNYYLTIPSQALELSLWLEAD
RFRYPSLNETTVKNQQGAVLEEMATSIDNQPYVRKAMEFLLSQVEGTPYGHAVIGSVADVKAATPQSLNAFHQRYYRPDA
MQLSLVGDIPKQTQDWIDAQFSDWQAPDIELTQMDDLKVSPKPVYGEIVDERGPWPAVLFAWHTVGSNSKDAAGLALLEA
YLFQNKSSLIQGTSLSDPDQLLSYSIPLTMTHHGMTNLVLVPRARTSLDKLSKNVESLIASVAAQTLDDAHLCQLKQIWL
NKALSTLDSPSRLARSLSATQPRDKLHPLTGPWQRIDAVSAKELQAIAQRYFIGNTVRLDLLPPWYIRATKSILELLPKE
MSDSLEESVM

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=222, Percent_Identity=27.4774774774775, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI155969707, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1787770, Length=197, Percent_Identity=29.9492385786802, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI2367164, Length=196, Percent_Identity=29.5918367346939, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71999683, Length=447, Percent_Identity=22.1476510067114, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17553678, Length=303, Percent_Identity=24.4224422442244, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21357875, Length=192, Percent_Identity=25.5208333333333, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646943, Length=192, Percent_Identity=25.5208333333333, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 54548; Mature: 54548

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLIFINKAKNYITTVTVAALSTLAISLPVSALTKTEPAACNLNKLAQPLYEVEQRIQY
CCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
RQLDNGLQVRTLPLKNTQAVSIASQFDVGSRNEVKGQAGYAHLFEHMLFKGSKHAPGDSY
HHHCCCCEEEEECCCCCCEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHH
TQTMSALSGQFNASTFFDFTNYYLTIPSQALELSLWLEADRFRYPSLNETTVKNQQGAVL
HHHHHHHCCCCCCCEEEEECCEEEECCCHHEEEEEEEECCCCCCCCCCCCCCCCCCCHHH
EEMATSIDNQPYVRKAMEFLLSQVEGTPYGHAVIGSVADVKAATPQSLNAFHQRYYRPDA
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHCCCCC
MQLSLVGDIPKQTQDWIDAQFSDWQAPDIELTQMDDLKVSPKPVYGEIVDERGPWPAVLF
EEEEEECCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCCCEEEE
AWHTVGSNSKDAAGLALLEAYLFQNKSSLIQGTSLSDPDQLLSYSIPLTMTHHGMTNLVL
EEECCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHCCCCEEEECCCCCEEEE
VPRARTSLDKLSKNVESLIASVAAQTLDDAHLCQLKQIWLNKALSTLDSPSRLARSLSAT
ECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
QPRDKLHPLTGPWQRIDAVSAKELQAIAQRYFIGNTVRLDLLPPWYIRATKSILELLPKE
CCHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
MSDSLEESVM
HHHHHHHHCC
>Mature Secondary Structure
MKRLIFINKAKNYITTVTVAALSTLAISLPVSALTKTEPAACNLNKLAQPLYEVEQRIQY
CCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
RQLDNGLQVRTLPLKNTQAVSIASQFDVGSRNEVKGQAGYAHLFEHMLFKGSKHAPGDSY
HHHCCCCEEEEECCCCCCEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHH
TQTMSALSGQFNASTFFDFTNYYLTIPSQALELSLWLEADRFRYPSLNETTVKNQQGAVL
HHHHHHHCCCCCCCEEEEECCEEEECCCHHEEEEEEEECCCCCCCCCCCCCCCCCCCHHH
EEMATSIDNQPYVRKAMEFLLSQVEGTPYGHAVIGSVADVKAATPQSLNAFHQRYYRPDA
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHCCCCCHHHHHHHHHHCCCCC
MQLSLVGDIPKQTQDWIDAQFSDWQAPDIELTQMDDLKVSPKPVYGEIVDERGPWPAVLF
EEEEEECCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCCCEEEE
AWHTVGSNSKDAAGLALLEAYLFQNKSSLIQGTSLSDPDQLLSYSIPLTMTHHGMTNLVL
EEECCCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHCCCCEEEECCCCCEEEE
VPRARTSLDKLSKNVESLIASVAAQTLDDAHLCQLKQIWLNKALSTLDSPSRLARSLSAT
ECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
QPRDKLHPLTGPWQRIDAVSAKELQAIAQRYFIGNTVRLDLLPPWYIRATKSILELLPKE
CCHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
MSDSLEESVM
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]