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The map label for this gene is norR [H]

Identifier: 157963258

GI number: 157963258

Start: 4209369

End: 4210919

Strand: Direct

Name: norR [H]

Synonym: Spea_3444

Alternate gene names: 157963258

Gene position: 4209369-4210919 (Clockwise)

Preceding gene: 157963255

Following gene: 157963259

Centisome position: 81.35

GC content: 49.07

Gene sequence:

>1551_bases
ATGGCACTGAGTCAAAGCGACCTTACCCGTATTGCACTGGATATCACTTCAGGCTTGTCCGACCATGACAGATTCTCAAG
GCTACTCGATACAGTGAGGCAAACTCTGCACTGTGACGCCGCCGCGCTGCTGCAATTTACTGGGCGACAATTTACGCCGC
TGGCGATCGATGGTTTGAGCCCCGACGTGCTAGGCAGGCGCTTTATCTTAAGCGAGCATCCAAGGCTCGAGGCCATTGCT
CGTGCTGGCGATGTGGTGAGATTTCCTGCCGACAGTGAACTACCCGACCCTTATGATGGTTTAATCCCTCATCAAGAAGA
TCATTTGATGGTGCATGCCTGTATTGGTCTGCCTTTAGTCGCTGACGGCGCGCTTATCGGCGCGGTCACTATCGATGGTT
TCGACCCTGAGCAGTTCAACGATTTTAGCGATAAAGAGCTACGCACCTTAAGTGCTATCGCTTCGGCATCACTGAATAAC
GCCCTGCTTATTGAGAAGCTAGAAAAACAGGCGCTGCAGTCGCAAGAGCCATCATCATTTAATCACAGCAGCGACAGTGA
AGTTGAAATGATTGGCCAATCACCTGCCATGCTAGCGATGAAAAATGAGCTTAAGGTAGTGGCCAGCACCGATCTTAACG
TGTTGATTTTAGGTGATACAGGTACCGGTAAGGAGCTAGTCGCTAAATCCATCCACCAAGGTTCTCCCCGTTCAAGCAAG
TCTCTGGTTTATCTTAACTGCGCAGCATTACCAGAATCTGTCGCCGAAAGTGAGCTGTTCGGTCATGTAAAAGGGGCCTT
TACTGGCGCTATCAGCCACCGTAGTGGTAAGTTTGAAATCGCCGATAAGGGCACACTATTTTTAGATGAAATAGGCGAGT
TACCGCTGTCATTACAGTCTAAATTGCTGCGAGTATTACAGTATGGCGACTTGCAAAAAGTCGGCTCAGATAAAAGCCTA
AAAGTGGATGTGCGGATCATTGCCGCTACCAATAAAGATCTCAAACAAGAAGTGTTAGCGGGTCGTTTTAGAGCCGACCT
TTACCACAGACTCAGTGTATTTCCCGTTATAGTGCCGCCTCTAAAAGAGCGCGAAGGTGACATTATTTTACTGAGCGGTT
TCTTCGTCGAGCGCAGCAGAGGGAAATTGGGTCTAAAGAGCCTTAGACTCAGCCCAGATAGCATAAAATTGCTAAACAGT
TACGACTGGCCCGGTAATGTGCGAGAACTCGAACATGTATTGCACCGCGCCGCGGTGTTAGCTCGCGCCCAAGCCCAATC
TAACATTGCACTGATCACGCCGCAGCACTTTGATTTTTATAATCAACAAGCAAAAAATATCGCAGCAGTGCCCCCTAGTA
TCGGCTCTAAATCAGTCTTACAGTCAACAAAGACTGAGCAAACTCTTAAGCTGGCAACCGAAGCATTTCAGGCGCAATAT
ATTCGCCAAGCATTAGCTGCCAACGGCCATAACTGGGCGGCAACCGCAAGGGCACTCGATGTCGACTCGGGCAACCTACA
CCGCCTAGCAAAGCGCATCGGCATAAAATAA

Upstream 100 bases:

>100_bases
TCTAGTAGCCTATATGCATGCACTAGAAATCAGCACACTGGAATGTGCGCACTAGAAAACTCGCACAAGGTTAACGATTT
AACCTGAAATTGGAGCACCC

Downstream 100 bases:

>100_bases
CTCGGACGTTAAAGAGGGTTAAAAGGAATTGAAACGATTAATATTCATCAACAAAGCGAAAAACTATATCACCACAGTGA
CTGTGGCAGCCCTGTCGACA

Product: anaerobic nitric oxide reductase transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MALSQSDLTRIALDITSGLSDHDRFSRLLDTVRQTLHCDAAALLQFTGRQFTPLAIDGLSPDVLGRRFILSEHPRLEAIA
RAGDVVRFPADSELPDPYDGLIPHQEDHLMVHACIGLPLVADGALIGAVTIDGFDPEQFNDFSDKELRTLSAIASASLNN
ALLIEKLEKQALQSQEPSSFNHSSDSEVEMIGQSPAMLAMKNELKVVASTDLNVLILGDTGTGKELVAKSIHQGSPRSSK
SLVYLNCAALPESVAESELFGHVKGAFTGAISHRSGKFEIADKGTLFLDEIGELPLSLQSKLLRVLQYGDLQKVGSDKSL
KVDVRIIAATNKDLKQEVLAGRFRADLYHRLSVFPVIVPPLKEREGDIILLSGFFVERSRGKLGLKSLRLSPDSIKLLNS
YDWPGNVRELEHVLHRAAVLARAQAQSNIALITPQHFDFYNQQAKNIAAVPPSIGSKSVLQSTKTEQTLKLATEAFQAQY
IRQALAANGHNWAATARALDVDSGNLHRLAKRIGIK

Sequences:

>Translated_516_residues
MALSQSDLTRIALDITSGLSDHDRFSRLLDTVRQTLHCDAAALLQFTGRQFTPLAIDGLSPDVLGRRFILSEHPRLEAIA
RAGDVVRFPADSELPDPYDGLIPHQEDHLMVHACIGLPLVADGALIGAVTIDGFDPEQFNDFSDKELRTLSAIASASLNN
ALLIEKLEKQALQSQEPSSFNHSSDSEVEMIGQSPAMLAMKNELKVVASTDLNVLILGDTGTGKELVAKSIHQGSPRSSK
SLVYLNCAALPESVAESELFGHVKGAFTGAISHRSGKFEIADKGTLFLDEIGELPLSLQSKLLRVLQYGDLQKVGSDKSL
KVDVRIIAATNKDLKQEVLAGRFRADLYHRLSVFPVIVPPLKEREGDIILLSGFFVERSRGKLGLKSLRLSPDSIKLLNS
YDWPGNVRELEHVLHRAAVLARAQAQSNIALITPQHFDFYNQQAKNIAAVPPSIGSKSVLQSTKTEQTLKLATEAFQAQY
IRQALAANGHNWAATARALDVDSGNLHRLAKRIGIK
>Mature_515_residues
ALSQSDLTRIALDITSGLSDHDRFSRLLDTVRQTLHCDAAALLQFTGRQFTPLAIDGLSPDVLGRRFILSEHPRLEAIAR
AGDVVRFPADSELPDPYDGLIPHQEDHLMVHACIGLPLVADGALIGAVTIDGFDPEQFNDFSDKELRTLSAIASASLNNA
LLIEKLEKQALQSQEPSSFNHSSDSEVEMIGQSPAMLAMKNELKVVASTDLNVLILGDTGTGKELVAKSIHQGSPRSSKS
LVYLNCAALPESVAESELFGHVKGAFTGAISHRSGKFEIADKGTLFLDEIGELPLSLQSKLLRVLQYGDLQKVGSDKSLK
VDVRIIAATNKDLKQEVLAGRFRADLYHRLSVFPVIVPPLKEREGDIILLSGFFVERSRGKLGLKSLRLSPDSIKLLNSY
DWPGNVRELEHVLHRAAVLARAQAQSNIALITPQHFDFYNQQAKNIAAVPPSIGSKSVLQSTKTEQTLKLATEAFQAQYI
RQALAANGHNWAATARALDVDSGNLHRLAKRIGIK

Specific function: Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54 [H]

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082152, Length=518, Percent_Identity=61.5830115830116, Blast_Score=613, Evalue=1e-177,
Organism=Escherichia coli, GI1789087, Length=334, Percent_Identity=41.6167664670659, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI87082117, Length=237, Percent_Identity=52.3206751054852, Blast_Score=256, Evalue=4e-69,
Organism=Escherichia coli, GI1790437, Length=270, Percent_Identity=50.7407407407407, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1788550, Length=231, Percent_Identity=48.4848484848485, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1790299, Length=262, Percent_Identity=45.0381679389313, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1788905, Length=231, Percent_Identity=46.3203463203463, Blast_Score=221, Evalue=8e-59,
Organism=Escherichia coli, GI1789233, Length=326, Percent_Identity=36.5030674846626, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1786524, Length=263, Percent_Identity=43.3460076045627, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI87081872, Length=230, Percent_Identity=44.3478260869565, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI1787583, Length=248, Percent_Identity=41.1290322580645, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1789828, Length=312, Percent_Identity=32.6923076923077, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081858, Length=212, Percent_Identity=33.4905660377358, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002078 [H]

Pfam domain/function: PF01590 GAF; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 56272; Mature: 56141

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSQSDLTRIALDITSGLSDHDRFSRLLDTVRQTLHCDAAALLQFTGRQFTPLAIDGLS
CCCCHHHHHEEEEEHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEECCCC
PDVLGRRFILSEHPRLEAIARAGDVVRFPADSELPDPYDGLIPHQEDHLMVHACIGLPLV
HHHHCCHHHHCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEE
ADGALIGAVTIDGFDPEQFNDFSDKELRTLSAIASASLNNALLIEKLEKQALQSQEPSSF
ECCEEEEEEEECCCCHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
NHSSDSEVEMIGQSPAMLAMKNELKVVASTDLNVLILGDTGTGKELVAKSIHQGSPRSSK
CCCCCCCCEEECCCCCEEEECCCEEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCC
SLVYLNCAALPESVAESELFGHVKGAFTGAISHRSGKFEIADKGTLFLDEIGELPLSLQS
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEECCCCCEEHHHHCCCCHHHHH
KLLRVLQYGDLQKVGSDKSLKVDVRIIAATNKDLKQEVLAGRFRADLYHRLSVFPVIVPP
HHHHHHHCCCHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEECCC
LKEREGDIILLSGFFVERSRGKLGLKSLRLSPDSIKLLNSYDWPGNVRELEHVLHRAAVL
CCCCCCCEEEEEEEEEECCCCCCCHHHEECCCCHHHEEECCCCCCCHHHHHHHHHHHHHH
ARAQAQSNIALITPQHFDFYNQQAKNIAAVPPSIGSKSVLQSTKTEQTLKLATEAFQAQY
HHHHHCCCEEEECCCHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IRQALAANGHNWAATARALDVDSGNLHRLAKRIGIK
HHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure 
ALSQSDLTRIALDITSGLSDHDRFSRLLDTVRQTLHCDAAALLQFTGRQFTPLAIDGLS
CCCHHHHHEEEEEHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEECCCC
PDVLGRRFILSEHPRLEAIARAGDVVRFPADSELPDPYDGLIPHQEDHLMVHACIGLPLV
HHHHCCHHHHCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEE
ADGALIGAVTIDGFDPEQFNDFSDKELRTLSAIASASLNNALLIEKLEKQALQSQEPSSF
ECCEEEEEEEECCCCHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
NHSSDSEVEMIGQSPAMLAMKNELKVVASTDLNVLILGDTGTGKELVAKSIHQGSPRSSK
CCCCCCCCEEECCCCCEEEECCCEEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCC
SLVYLNCAALPESVAESELFGHVKGAFTGAISHRSGKFEIADKGTLFLDEIGELPLSLQS
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEECCCCCEEHHHHCCCCHHHHH
KLLRVLQYGDLQKVGSDKSLKVDVRIIAATNKDLKQEVLAGRFRADLYHRLSVFPVIVPP
HHHHHHHCCCHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEECCC
LKEREGDIILLSGFFVERSRGKLGLKSLRLSPDSIKLLNSYDWPGNVRELEHVLHRAAVL
CCCCCCCEEEEEEEEEECCCCCCCHHHEECCCCHHHEEECCCCCCCHHHHHHHHHHHHHH
ARAQAQSNIALITPQHFDFYNQQAKNIAAVPPSIGSKSVLQSTKTEQTLKLATEAFQAQY
HHHHHCCCEEEECCCHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IRQALAANGHNWAATARALDVDSGNLHRLAKRIGIK
HHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA