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The map label for this gene is ifcA [H]

Identifier: 157963183

GI number: 157963183

Start: 4115174

End: 4116733

Strand: Direct

Name: ifcA [H]

Synonym: Spea_3368

Alternate gene names: 157963183

Gene position: 4115174-4116733 (Clockwise)

Preceding gene: 157963181

Following gene: 157963184

Centisome position: 79.53

GC content: 51.15

Gene sequence:

>1560_bases
ATGAACGAAAAAGAACTGGCGAGTCCTAGCAGACGCCAACTACTGAAAGGCGGTGCTGCGATGGCAGTTGCAGGCTTAGG
TAGCACTGTTGCCTTGTCGGCAAACGCCGCTTGCGTCTCTATAGAAGAAGCCAAGTTTGACGAAGTTGTCGACGTTATCG
TCGTTGGCAGTGGCTTTGCGGGTATGTCTGCAGCGCTACAGGCAAAAGAAGCTGGCGCAAGCGTTATGGTTATCGACAAG
ATGCCAGTCTTTGGAGGTAACTCTACTATCAACGGCGGCGCAATGGCGGTGGCAGGCTCACCTCTACAGAAGAAAGAAGG
CATCGAAGATTCTGTCGACGTCATGGTTGCCGACATGCTGGAGTCAGGTCGCGGCATGAACGATGTCGAGATGCTAAAGC
TTGTGTGTAATGGCACAGCCGAGTCTTGTGAATGGCTAATCGATCACGGTGTAGAGTGGAAACCTTTCGTACAACACTTC
GGCGGCCACTCAATTCCACGCGTATTACAAACAGTACAGAGTTCGGGCGCAGGCATTATTCGTCCACTAATCAAAGCGGC
TAAGAAGAGTGGCATCGAAATGCGCAATCAAGCCAAGCTCGAAGGCTTTATTAAAGATGAAAGCGGCCGTGTTATCGGTC
TAGACGTGCGCCAAGGTTATTACTTCCCTAAAGACCGCACCGGAAAAATGGTTAAAATTGGTGCCCGTAAAGGCGTGATC
ATGGCAACGGGTGGTTTCGGTAACGATATTGAATACCGTCAAATGCAGCAACCTGAATATACCAGTGAGCTGGACTCGAC
CAACCACGCAGGAGCAACCTCTGAAGCACTTAAGCAGATGATGCTACTGGGTGCCAACCCAATTCACTTAGATCAGATCC
AGCTTGGCCCATGGGCATCTCCCGATGAGAAAGGCTTCGGTACTGCATCGCAGTTCAACACGATTGCGACCTACCCTAGT
GGCATCGTAGTTGACGTACGCACAGGCGAGCGCTTCTTTAATGAACTCGCCGACCGTAAGGCTCGTGCCGACGCCATCAT
GACTCGTCGCGACGAACAAGGTAAGCCAGTATACCCAATCGGCTTTACCAATGCCGAAGGCGCCAAAGATGCACAAACTC
TAGCTTGGGGCCTTAAATACAATGTTATTAAGAAAGCCGACAACCTAGACGAACTAGCCAAAATCTACAACATGCCAGCC
GAAGCGCTAAAAGCACAGGTTGCACGCTGGAACGAAGCCGTCACCAAGGGTGAAGACGGTGAGTTTGGTCGTCCAATGCA
AAAAGCTATGTTGCTAGACAAAGGCCCTTGGTATGGCGTACGCATGTGGCCAAAAGTTCACTACTGCATGGGTGGCGTTA
AGGTAAACACCGCCTCAGAAGTACTACACCTTGTCAGCAACAAACCAATCCCAGGTCTATACGCAGCGGGTGAAGCCACT
GGTGGCATTCACGGTGCCAGTCGTTTAGGTGCCTGCGCGGTAGCTGAAGGAGTAGTAACTGGACGTAATGCTGGTCGTCA
TTGTTCACAGAGCCAGCCAGTGAAACTGAATCTCGCTTAG

Upstream 100 bases:

>100_bases
CCATTATTAGCGAGTTGGCACAGTCGCTGCACTTTATCTGCATACATTGGGCTCCAATAGCCTGATAAACAAATTAAAAT
CGATATAGGGAAACAGATAG

Downstream 100 bases:

>100_bases
CTCAAATAAAAATCAAATTCGCTTAGCTAAGTGCCCTGCACTGAGCAGCAAAAAATTATGGAATTGATCAAGATGAAAAC
AACTAAAAATGCTGTATTAA

Product: flavocytochrome c

Products: NA

Alternate protein names: Fe(3+)-induced flavocytochrome C3; Ifc3; Iron(III)-induced flavocytochrome C3 [H]

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MNEKELASPSRRQLLKGGAAMAVAGLGSTVALSANAACVSIEEAKFDEVVDVIVVGSGFAGMSAALQAKEAGASVMVIDK
MPVFGGNSTINGGAMAVAGSPLQKKEGIEDSVDVMVADMLESGRGMNDVEMLKLVCNGTAESCEWLIDHGVEWKPFVQHF
GGHSIPRVLQTVQSSGAGIIRPLIKAAKKSGIEMRNQAKLEGFIKDESGRVIGLDVRQGYYFPKDRTGKMVKIGARKGVI
MATGGFGNDIEYRQMQQPEYTSELDSTNHAGATSEALKQMMLLGANPIHLDQIQLGPWASPDEKGFGTASQFNTIATYPS
GIVVDVRTGERFFNELADRKARADAIMTRRDEQGKPVYPIGFTNAEGAKDAQTLAWGLKYNVIKKADNLDELAKIYNMPA
EALKAQVARWNEAVTKGEDGEFGRPMQKAMLLDKGPWYGVRMWPKVHYCMGGVKVNTASEVLHLVSNKPIPGLYAAGEAT
GGIHGASRLGACAVAEGVVTGRNAGRHCSQSQPVKLNLA

Sequences:

>Translated_519_residues
MNEKELASPSRRQLLKGGAAMAVAGLGSTVALSANAACVSIEEAKFDEVVDVIVVGSGFAGMSAALQAKEAGASVMVIDK
MPVFGGNSTINGGAMAVAGSPLQKKEGIEDSVDVMVADMLESGRGMNDVEMLKLVCNGTAESCEWLIDHGVEWKPFVQHF
GGHSIPRVLQTVQSSGAGIIRPLIKAAKKSGIEMRNQAKLEGFIKDESGRVIGLDVRQGYYFPKDRTGKMVKIGARKGVI
MATGGFGNDIEYRQMQQPEYTSELDSTNHAGATSEALKQMMLLGANPIHLDQIQLGPWASPDEKGFGTASQFNTIATYPS
GIVVDVRTGERFFNELADRKARADAIMTRRDEQGKPVYPIGFTNAEGAKDAQTLAWGLKYNVIKKADNLDELAKIYNMPA
EALKAQVARWNEAVTKGEDGEFGRPMQKAMLLDKGPWYGVRMWPKVHYCMGGVKVNTASEVLHLVSNKPIPGLYAAGEAT
GGIHGASRLGACAVAEGVVTGRNAGRHCSQSQPVKLNLA
>Mature_519_residues
MNEKELASPSRRQLLKGGAAMAVAGLGSTVALSANAACVSIEEAKFDEVVDVIVVGSGFAGMSAALQAKEAGASVMVIDK
MPVFGGNSTINGGAMAVAGSPLQKKEGIEDSVDVMVADMLESGRGMNDVEMLKLVCNGTAESCEWLIDHGVEWKPFVQHF
GGHSIPRVLQTVQSSGAGIIRPLIKAAKKSGIEMRNQAKLEGFIKDESGRVIGLDVRQGYYFPKDRTGKMVKIGARKGVI
MATGGFGNDIEYRQMQQPEYTSELDSTNHAGATSEALKQMMLLGANPIHLDQIQLGPWASPDEKGFGTASQFNTIATYPS
GIVVDVRTGERFFNELADRKARADAIMTRRDEQGKPVYPIGFTNAEGAKDAQTLAWGLKYNVIKKADNLDELAKIYNMPA
EALKAQVARWNEAVTKGEDGEFGRPMQKAMLLDKGPWYGVRMWPKVHYCMGGVKVNTASEVLHLVSNKPIPGLYAAGEAT
GGIHGASRLGACAVAEGVVTGRNAGRHCSQSQPVKLNLA

Specific function: Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1788928, Length=219, Percent_Identity=28.310502283105, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71986328, Length=487, Percent_Identity=28.7474332648871, Blast_Score=148, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6320788, Length=480, Percent_Identity=26.6666666666667, Blast_Score=138, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6322511, Length=485, Percent_Identity=25.360824742268, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 55446; Mature: 55446

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKELASPSRRQLLKGGAAMAVAGLGSTVALSANAACVSIEEAKFDEVVDVIVVGSGFA
CCCHHCCCHHHHHHHHCCCCEEEECCCCEEEEECCCEEEEEHHHHHHHHEEEEEECCCCC
GMSAALQAKEAGASVMVIDKMPVFGGNSTINGGAMAVAGSPLQKKEGIEDSVDVMVADML
CHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHH
ESGRGMNDVEMLKLVCNGTAESCEWLIDHGVEWKPFVQHFGGHSIPRVLQTVQSSGAGII
HCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHCCCHHH
RPLIKAAKKSGIEMRNQAKLEGFIKDESGRVIGLDVRQGYYFPKDRTGKMVKIGARKGVI
HHHHHHHHHCCCCHHHHHHHEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCEE
MATGGFGNDIEYRQMQQPEYTSELDSTNHAGATSEALKQMMLLGANPIHLDQIQLGPWAS
EEECCCCCCCHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCC
PDEKGFGTASQFNTIATYPSGIVVDVRTGERFFNELADRKARADAIMTRRDEQGKPVYPI
CCCCCCCCHHHCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
GFTNAEGAKDAQTLAWGLKYNVIKKADNLDELAKIYNMPAEALKAQVARWNEAVTKGEDG
CCCCCCCCCCHHHHHHHHEHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
EFGRPMQKAMLLDKGPWYGVRMWPKVHYCMGGVKVNTASEVLHLVSNKPIPGLYAAGEAT
CCCCHHHHHHHHCCCCCCCEEECCEEEEHCCCEEECHHHHHHHHHHCCCCCCEEECCCCC
GGIHGASRLGACAVAEGVVTGRNAGRHCSQSQPVKLNLA
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MNEKELASPSRRQLLKGGAAMAVAGLGSTVALSANAACVSIEEAKFDEVVDVIVVGSGFA
CCCHHCCCHHHHHHHHCCCCEEEECCCCEEEEECCCEEEEEHHHHHHHHEEEEEECCCCC
GMSAALQAKEAGASVMVIDKMPVFGGNSTINGGAMAVAGSPLQKKEGIEDSVDVMVADML
CHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHH
ESGRGMNDVEMLKLVCNGTAESCEWLIDHGVEWKPFVQHFGGHSIPRVLQTVQSSGAGII
HCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHCCCHHH
RPLIKAAKKSGIEMRNQAKLEGFIKDESGRVIGLDVRQGYYFPKDRTGKMVKIGARKGVI
HHHHHHHHHCCCCHHHHHHHEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCEE
MATGGFGNDIEYRQMQQPEYTSELDSTNHAGATSEALKQMMLLGANPIHLDQIQLGPWAS
EEECCCCCCCHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCC
PDEKGFGTASQFNTIATYPSGIVVDVRTGERFFNELADRKARADAIMTRRDEQGKPVYPI
CCCCCCCCHHHCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
GFTNAEGAKDAQTLAWGLKYNVIKKADNLDELAKIYNMPAEALKAQVARWNEAVTKGEDG
CCCCCCCCCCHHHHHHHHEHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
EFGRPMQKAMLLDKGPWYGVRMWPKVHYCMGGVKVNTASEVLHLVSNKPIPGLYAAGEAT
CCCCHHHHHHHHCCCCCCCEEECCEEEEHCCCEEECHHHHHHHHHHCCCCCCEEECCCCC
GGIHGASRLGACAVAEGVVTGRNAGRHCSQSQPVKLNLA
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10455032; 10581549 [H]