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The map label for this gene is torA [H]

Identifier: 157963159

GI number: 157963159

Start: 4084665

End: 4087157

Strand: Direct

Name: torA [H]

Synonym: Spea_3343

Alternate gene names: 157963159

Gene position: 4084665-4087157 (Clockwise)

Preceding gene: 157963158

Following gene: 157963160

Centisome position: 78.94

GC content: 46.65

Gene sequence:

>2493_bases
ATGAACAGAAGAGACTTTCTAAAAGGCTTAGTTGGAACATCTTATGTCGTACTTAGCGGTTCATCAGTACTTGCACCGCT
AAACGCTTTAGCGGCATCAGGAGCTGATGCGTCAGACGGTTGGCTTACAACTGGTTCGCACATGGGTGCGTTCAAGATGA
AGCGTAAAAACGGCGTGATCTCTGAAGTTAAGCCTTTCGATACCGATATGTATCCAACAGATATGATCAACGGTATTAAG
GGCTTAGTTTACAACCCATCACGCGTTCGCTACCCAATGGTTCGCTTAGACTTTTTATTGAAAGGTCACCAAAGCGATAC
CACACAACGCGGTGACTTCCGCTTTGTACGTGTGACTTGGGACAAGGCGCTCGGTTTATTTAAAGACTCACTCGATCTTA
TTCAAACTAAATATGGTCCATCGGGACTACACGCGGGGCAAACAGGTTGGCGTGCAACGGGTCAGTTGCATTCAAGCACC
AGCCATATGCAACGCGCTGTGGGCATGCATGGTAACTTCGTTAAGAAGATTGGTGACTATTCAACAGGTGCAGGGCAAAC
CATTTTGCCTTACATCTTAGGTTCTACCGAAGTTTACGCTCAAGGTACCTCTTGGTCGTTAATTCTGGAACATTCTAAAA
CCATCATTTTATGGTCGAATGATCCATACAAGAACCTACAGGTCGGCTGGAACGCTGAAACACATGAGTCTTATGCTTAC
CTTGCTCAATTAAAAGAGAAAGTAGCCAAAGGCGAAATTCGTGTGATCAGTATCGATCCTGTCGTCACGAAAACACAGCA
ATACCTAGGTTGTGAGCAACTTTACATTAATCCGCAAACCGACGTAGCGTTAATGCTCGGTATTGCTCACGAAATGGTAG
ACAAGAACCTTCACGATAATGCGTTTATCGAAGGTTATAGCTTAGGCTTCGATCAGTTCTTACCTTACATTAAAGGCGAA
ACTGACGGTGTTGAGAAAACACCTGAGTGGGCAGCGGAGATCACAGGCGTTTCAGCCGAGATCATCCGTGATCTTGCTAA
GGTAATGACAAAAGATCGCACCCAGATGTTGATGGGCTGGTGTATTCAGCGTCAACAACATGGTGAGCAGCCTTATTGGA
TGGCAGCGGTACTTGCAACCATGATTGGCCAAATTGGTCTTCCGGGCGGCGGCATTAGTTATGGTCACCACTACTCAAGT
ATTGGTGTTCCGTCTTCGGGTGCGGCAGCGCCAGGTGCGTTCCCACGTAACTTAGATGATGGTCAGAAGCCAATTTTTGA
TAGCACTGATTTTAAAGGCGCGAGCAATACGATTCCAGTTGCTCGTTGGATTGACTCAATCCTAGAGCCAGGTAAAACCA
TTGACTCAAACGGCTCTAAAGTTACCTATCCAGACATTAAGATGATGGTGTTCTCGGGCAACAACCCATGGAACCATCAC
CAAGATCGTAACCGCATGAAGAAAGCGTTCCATAAGCTTGAGTGCATCGTGTCGATTGACATGAACTGGACGGCGACTTG
TCGTTTCTCTGACATAGTACTACCAGCTTGTACGACGTTTGAACGTAACGATATCGATATCTATGGCGCATACGCAAACC
GTGGTTTGCTTGCCATGCAGAAGATGGTTGAACCGTTATTTGAGAGTCTTTCTGATTTCGAGATCTTTACTCGTTTTGCT
GCACTACTTGGCAAAGAGAAAGAGTACACTCGCGGCATGACCGAGCACGATTGGTTAGTGAAGCTTTACAACGACTGTAA
AGCAGCAAACGCTGGCAAGTTCGAAATGCCTGAATTCGAAGAGTTCTGGAAAGCGGGTTATGTTTACTTCGGTGAAGGTG
AGCCTTGGGTTCGTCACGCGGCATTTAGAGATGATCCAGAAATCAACCCACTTGGAACACCATCTGGTTTGATTGAGATC
TTCAGCCGTAAGATTGCCCACTACGAATACGATGACTGCCCTGGCCACCCTACTTGGATGGAAAAAGCAGAACGTAGCCA
TGGCGGCCCTGGCTCAGACAAGCACCCAATTTGGCTGCAGTCTTGCCACCCAGATAAGCGTTTGCATTCACAAATGTGTG
AATCAGAAGAGTACCGTGAAACTTACACTGTACAAGGCCGTGAACCTGTATACCTAAACCCTGAAGATGCTAAGAAACGC
GGCATTAAATCAGGCGATGTGGTACGCGTGTTTAATGACCGTGGTCAGTTGCTTGCTGGTGCAGTGGTATCGGATAAGTT
CCCTAAAGGGGTTATCCGTATTCAAGAGGGTGCTTGGTATGGCCCAGTTGGTAAAGACGGTAGCAAAGAGGGCGGCGCAG
AAATTGGTGCTATCTGTAGTTATGGCGATCCAAACACTCTAACGCTAGATATCGGTACCTCTAAGCTTGCACAAGCTTGC
TCGGCTTATACCTGCCTTGTTGACTACGAAAAGTATCAAGGTAAAGTACCAGCAGTAAGTTCATTTAGCGGCCCGGTTGA
GATTGCATTATGA

Upstream 100 bases:

>100_bases
TCGTCAACATGGATCAAGATACCCAAGCTTTGGTACAGAAATATTTACAAGAGCATTCATCAACTTTCGATAAGTCGGCT
CACTAATAGGACATAGCGTA

Downstream 100 bases:

>100_bases
TTAAAGATGCTGTGAACACAGAGACAGTAGAAGTTAACCCAGTTGATCAGGTTAGAAGCACGATTTATCAATTACTTTCG
TCACTATTTGCCAAAGAAAT

Product: trimethylamine-N-oxide reductase TorA

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase [H]

Number of amino acids: Translated: 830; Mature: 830

Protein sequence:

>830_residues
MNRRDFLKGLVGTSYVVLSGSSVLAPLNALAASGADASDGWLTTGSHMGAFKMKRKNGVISEVKPFDTDMYPTDMINGIK
GLVYNPSRVRYPMVRLDFLLKGHQSDTTQRGDFRFVRVTWDKALGLFKDSLDLIQTKYGPSGLHAGQTGWRATGQLHSST
SHMQRAVGMHGNFVKKIGDYSTGAGQTILPYILGSTEVYAQGTSWSLILEHSKTIILWSNDPYKNLQVGWNAETHESYAY
LAQLKEKVAKGEIRVISIDPVVTKTQQYLGCEQLYINPQTDVALMLGIAHEMVDKNLHDNAFIEGYSLGFDQFLPYIKGE
TDGVEKTPEWAAEITGVSAEIIRDLAKVMTKDRTQMLMGWCIQRQQHGEQPYWMAAVLATMIGQIGLPGGGISYGHHYSS
IGVPSSGAAAPGAFPRNLDDGQKPIFDSTDFKGASNTIPVARWIDSILEPGKTIDSNGSKVTYPDIKMMVFSGNNPWNHH
QDRNRMKKAFHKLECIVSIDMNWTATCRFSDIVLPACTTFERNDIDIYGAYANRGLLAMQKMVEPLFESLSDFEIFTRFA
ALLGKEKEYTRGMTEHDWLVKLYNDCKAANAGKFEMPEFEEFWKAGYVYFGEGEPWVRHAAFRDDPEINPLGTPSGLIEI
FSRKIAHYEYDDCPGHPTWMEKAERSHGGPGSDKHPIWLQSCHPDKRLHSQMCESEEYRETYTVQGREPVYLNPEDAKKR
GIKSGDVVRVFNDRGQLLAGAVVSDKFPKGVIRIQEGAWYGPVGKDGSKEGGAEIGAICSYGDPNTLTLDIGTSKLAQAC
SAYTCLVDYEKYQGKVPAVSSFSGPVEIAL

Sequences:

>Translated_830_residues
MNRRDFLKGLVGTSYVVLSGSSVLAPLNALAASGADASDGWLTTGSHMGAFKMKRKNGVISEVKPFDTDMYPTDMINGIK
GLVYNPSRVRYPMVRLDFLLKGHQSDTTQRGDFRFVRVTWDKALGLFKDSLDLIQTKYGPSGLHAGQTGWRATGQLHSST
SHMQRAVGMHGNFVKKIGDYSTGAGQTILPYILGSTEVYAQGTSWSLILEHSKTIILWSNDPYKNLQVGWNAETHESYAY
LAQLKEKVAKGEIRVISIDPVVTKTQQYLGCEQLYINPQTDVALMLGIAHEMVDKNLHDNAFIEGYSLGFDQFLPYIKGE
TDGVEKTPEWAAEITGVSAEIIRDLAKVMTKDRTQMLMGWCIQRQQHGEQPYWMAAVLATMIGQIGLPGGGISYGHHYSS
IGVPSSGAAAPGAFPRNLDDGQKPIFDSTDFKGASNTIPVARWIDSILEPGKTIDSNGSKVTYPDIKMMVFSGNNPWNHH
QDRNRMKKAFHKLECIVSIDMNWTATCRFSDIVLPACTTFERNDIDIYGAYANRGLLAMQKMVEPLFESLSDFEIFTRFA
ALLGKEKEYTRGMTEHDWLVKLYNDCKAANAGKFEMPEFEEFWKAGYVYFGEGEPWVRHAAFRDDPEINPLGTPSGLIEI
FSRKIAHYEYDDCPGHPTWMEKAERSHGGPGSDKHPIWLQSCHPDKRLHSQMCESEEYRETYTVQGREPVYLNPEDAKKR
GIKSGDVVRVFNDRGQLLAGAVVSDKFPKGVIRIQEGAWYGPVGKDGSKEGGAEIGAICSYGDPNTLTLDIGTSKLAQAC
SAYTCLVDYEKYQGKVPAVSSFSGPVEIAL
>Mature_830_residues
MNRRDFLKGLVGTSYVVLSGSSVLAPLNALAASGADASDGWLTTGSHMGAFKMKRKNGVISEVKPFDTDMYPTDMINGIK
GLVYNPSRVRYPMVRLDFLLKGHQSDTTQRGDFRFVRVTWDKALGLFKDSLDLIQTKYGPSGLHAGQTGWRATGQLHSST
SHMQRAVGMHGNFVKKIGDYSTGAGQTILPYILGSTEVYAQGTSWSLILEHSKTIILWSNDPYKNLQVGWNAETHESYAY
LAQLKEKVAKGEIRVISIDPVVTKTQQYLGCEQLYINPQTDVALMLGIAHEMVDKNLHDNAFIEGYSLGFDQFLPYIKGE
TDGVEKTPEWAAEITGVSAEIIRDLAKVMTKDRTQMLMGWCIQRQQHGEQPYWMAAVLATMIGQIGLPGGGISYGHHYSS
IGVPSSGAAAPGAFPRNLDDGQKPIFDSTDFKGASNTIPVARWIDSILEPGKTIDSNGSKVTYPDIKMMVFSGNNPWNHH
QDRNRMKKAFHKLECIVSIDMNWTATCRFSDIVLPACTTFERNDIDIYGAYANRGLLAMQKMVEPLFESLSDFEIFTRFA
ALLGKEKEYTRGMTEHDWLVKLYNDCKAANAGKFEMPEFEEFWKAGYVYFGEGEPWVRHAAFRDDPEINPLGTPSGLIEI
FSRKIAHYEYDDCPGHPTWMEKAERSHGGPGSDKHPIWLQSCHPDKRLHSQMCESEEYRETYTVQGREPVYLNPEDAKKR
GIKSGDVVRVFNDRGQLLAGAVVSDKFPKGVIRIQEGAWYGPVGKDGSKEGGAEIGAICSYGDPNTLTLDIGTSKLAQAC
SAYTCLVDYEKYQGKVPAVSSFSGPVEIAL

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787231, Length=835, Percent_Identity=52.0958083832335, Blast_Score=877, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=845, Percent_Identity=39.1715976331361, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI145693196, Length=761, Percent_Identity=40.6044678055191, Blast_Score=574, Evalue=1e-165,
Organism=Escherichia coli, GI87081797, Length=864, Percent_Identity=29.9768518518519, Blast_Score=295, Evalue=9e-81,
Organism=Escherichia coli, GI1787870, Length=863, Percent_Identity=28.3893395133256, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI171474008, Length=773, Percent_Identity=29.1073738680466, Blast_Score=244, Evalue=2e-65,
Organism=Escherichia coli, GI3868721, Length=710, Percent_Identity=22.3943661971831, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 92177; Mature: 92177

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRDFLKGLVGTSYVVLSGSSVLAPLNALAASGADASDGWLTTGSHMGAFKMKRKNGVI
CCHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEHHCCCCH
SEVKPFDTDMYPTDMINGIKGLVYNPSRVRYPMVRLDFLLKGHQSDTTQRGDFRFVRVTW
HCCCCCCCCCCCHHHHHCCCCEEECCCCCCCHHHHEEHHHCCCCCCCCCCCCEEEEEEEH
DKALGLFKDSLDLIQTKYGPSGLHAGQTGWRATGQLHSSTSHMQRAVGMHGNFVKKIGDY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCC
STGAGQTILPYILGSTEVYAQGTSWSLILEHSKTIILWSNDPYKNLQVGWNAETHESYAY
CCCCCCEEHHHHCCCCEEEECCCCEEEEEECCCEEEEECCCCCCCCEECCCCCCHHHHHH
LAQLKEKVAKGEIRVISIDPVVTKTQQYLGCEQLYINPQTDVALMLGIAHEMVDKNLHDN
HHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCC
AFIEGYSLGFDQFLPYIKGETDGVEKTPEWAAEITGVSAEIIRDLAKVMTKDRTQMLMGW
CEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
CIQRQQHGEQPYWMAAVLATMIGQIGLPGGGISYGHHYSSIGVPSSGAAAPGAFPRNLDD
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GQKPIFDSTDFKGASNTIPVARWIDSILEPGKTIDSNGSKVTYPDIKMMVFSGNNPWNHH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEEECCCCCCCCC
QDRNRMKKAFHKLECIVSIDMNWTATCRFSDIVLPACTTFERNDIDIYGAYANRGLLAMQ
HHHHHHHHHHHHEEEEEEECCCEEEEEEECCEEECCCCCCCCCCCEEEECCCCCCHHHHH
KMVEPLFESLSDFEIFTRFAALLGKEKEYTRGMTEHDWLVKLYNDCKAANAGKFEMPEFE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHH
EFWKAGYVYFGEGEPWVRHAAFRDDPEINPLGTPSGLIEIFSRKIAHYEYDDCPGHPTWM
HHHHCCEEEECCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHH
EKAERSHGGPGSDKHPIWLQSCHPDKRLHSQMCESEEYRETYTVQGREPVYLNPEDAKKR
HHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHCCHHHHHEEEECCCCCEEECCCHHHHC
GIKSGDVVRVFNDRGQLLAGAVVSDKFPKGVIRIQEGAWYGPVGKDGSKEGGAEIGAICS
CCCCCCEEEEECCCCCEEECHHHHCCCCCCEEEEECCCEECCCCCCCCCCCCCCEEEEEE
YGDPNTLTLDIGTSKLAQACSAYTCLVDYEKYQGKVPAVSSFSGPVEIAL
CCCCCEEEEECCHHHHHHHHHHEEEEEEHHHHCCCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MNRRDFLKGLVGTSYVVLSGSSVLAPLNALAASGADASDGWLTTGSHMGAFKMKRKNGVI
CCHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEHHCCCCH
SEVKPFDTDMYPTDMINGIKGLVYNPSRVRYPMVRLDFLLKGHQSDTTQRGDFRFVRVTW
HCCCCCCCCCCCHHHHHCCCCEEECCCCCCCHHHHEEHHHCCCCCCCCCCCCEEEEEEEH
DKALGLFKDSLDLIQTKYGPSGLHAGQTGWRATGQLHSSTSHMQRAVGMHGNFVKKIGDY
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCC
STGAGQTILPYILGSTEVYAQGTSWSLILEHSKTIILWSNDPYKNLQVGWNAETHESYAY
CCCCCCEEHHHHCCCCEEEECCCCEEEEEECCCEEEEECCCCCCCCEECCCCCCHHHHHH
LAQLKEKVAKGEIRVISIDPVVTKTQQYLGCEQLYINPQTDVALMLGIAHEMVDKNLHDN
HHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCC
AFIEGYSLGFDQFLPYIKGETDGVEKTPEWAAEITGVSAEIIRDLAKVMTKDRTQMLMGW
CEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
CIQRQQHGEQPYWMAAVLATMIGQIGLPGGGISYGHHYSSIGVPSSGAAAPGAFPRNLDD
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GQKPIFDSTDFKGASNTIPVARWIDSILEPGKTIDSNGSKVTYPDIKMMVFSGNNPWNHH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEEECCCCCCCCC
QDRNRMKKAFHKLECIVSIDMNWTATCRFSDIVLPACTTFERNDIDIYGAYANRGLLAMQ
HHHHHHHHHHHHEEEEEEECCCEEEEEEECCEEECCCCCCCCCCCEEEECCCCCCHHHHH
KMVEPLFESLSDFEIFTRFAALLGKEKEYTRGMTEHDWLVKLYNDCKAANAGKFEMPEFE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHH
EFWKAGYVYFGEGEPWVRHAAFRDDPEINPLGTPSGLIEIFSRKIAHYEYDDCPGHPTWM
HHHHCCEEEECCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHH
EKAERSHGGPGSDKHPIWLQSCHPDKRLHSQMCESEEYRETYTVQGREPVYLNPEDAKKR
HHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHCCHHHHHEEEECCCCCEEECCCHHHHC
GIKSGDVVRVFNDRGQLLAGAVVSDKFPKGVIRIQEGAWYGPVGKDGSKEGGAEIGAICS
CCCCCCEEEEECCCCCEEECHHHHCCCCCCEEEEECCCEECCCCCCCCCCCCCCEEEEEE
YGDPNTLTLDIGTSKLAQACSAYTCLVDYEKYQGKVPAVSSFSGPVEIAL
CCCCCEEEEECCHHHHHHHHHHEEEEEEHHHHCCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9813127; 9813128 [H]