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The map label for this gene is gltS [H]

Identifier: 157963068

GI number: 157963068

Start: 3987774

End: 3988997

Strand: Direct

Name: gltS [H]

Synonym: Spea_3251

Alternate gene names: 157963068

Gene position: 3987774-3988997 (Clockwise)

Preceding gene: 157963066

Following gene: 157963077

Centisome position: 77.06

GC content: 46.81

Gene sequence:

>1224_bases
ATGAATACAGTTTATACAATCGGCGAACTAGAATCGTTTTTGGTAGCGATCCTAGTGCTGTTCATCGGGCATACGGTCAA
TCGTCATATTCCTATATTGAAAAAATATAATATCCCCGAACCTATTGTCGGCGGCCTGTTGATAGCAGCATTAATCACGG
TATTGCATTTCAACGATATTACCGTGGCATTTAGCCTATCGATGCAAAACACCTTGATGTTGATGTTCTTCAGCACTGTT
GGTCTGGCGGCAAACTATAAGCTATTGCTCAAGGGAGGCAGTAAGGTATTTCTGTTCCTTGGTGTCGCCTCCTTATTTAT
TGTGATCCAAAATATTGTCGGTGTTAGTCTTGCCAATCTGTTGGGCCTTGAGTCATTTATGGGCTTAATCGCAGGCTCTA
TCACTCTATCTGGTGGCCACGGTACCGGAGCCGCTTGGGCTGATACCTTCCAAAGTGAATATGGTATCAATACCCTTGAG
TTCGCCATGGCGGCGGCAACATTTGGTTTGGTGATGGGTGGTATTATCGGTGGCCCCGTGGCGCAGCGACTCATCAACAA
GAACAACTTGGTATCGAGCTACGGTGTTGGCGGTAACCACCATACAGACCATCCAGATCTGGTTACCTATGATCAATTTG
AAGAAGACAGAGTCACGGCTAAAAGTGTATTAGAAACCCTGTTTATCATGCTGCTGTGTGTGGCGGGAGCGAAGTGGACT
ACGCTGTTAATCGATACAGTCGGTGCCAGTTGGCTGAAGATGCCAGAATTCGTTTATGCGCTGTTTATTGGTGTGATCAT
TACTAACCTAACCGAGATCTCTCGCGGCTATAAGATCAACAGTGAGTGTGTCGACGTACTCGGCTCGGTGTCTCTCGCAT
TATTCCTATCGATGGCTTTGATGAACTTAAAGCTGTGGGAGATTTTTGATCTTGCCATTCCACTGCTGATCATCCTTGTT
GTGCAAACTGCCGTACTAGGACTGTTTGCCTACTTTGTGACATTTAAGATGATGGGCAGCAACTATGATGCTGCGGTTAT
GGCTGGCGGTCATTGCGGTTTTGGCCTAGGTGCGACTCCAACAGCGGTGATGAACATGGGCGCTTTGGTATCGAGAACCG
GTCCGTCACCACAAGCCTTTATGGTAGTCCCCATTGTGGGTGCCTTCTTCGTGGATATCGTTAACGCGGTGATCCTAAAA
GGCTTCATGATTTTTGTTGGCTAG

Upstream 100 bases:

>100_bases
AAAAAGGCATGACCAAACACAAATAACCAAATAAAAACAAAAGTTTAATAACAAAAAGGTCACTTACTGCAACAACTTAA
CCTATTTTGCAAGGAATCAT

Downstream 100 bases:

>100_bases
GTTTCAATAGCAAGCAGCATTCATAGCCGTAAAAAAGCCAGCGATTAACGCTGGCTTTTTAGTCTTTGCTTTATAAAGAA
GGGGCTAGGTTCTAGGGCGC

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNTVYTIGELESFLVAILVLFIGHTVNRHIPILKKYNIPEPIVGGLLIAALITVLHFNDITVAFSLSMQNTLMLMFFSTV
GLAANYKLLLKGGSKVFLFLGVASLFIVIQNIVGVSLANLLGLESFMGLIAGSITLSGGHGTGAAWADTFQSEYGINTLE
FAMAAATFGLVMGGIIGGPVAQRLINKNNLVSSYGVGGNHHTDHPDLVTYDQFEEDRVTAKSVLETLFIMLLCVAGAKWT
TLLIDTVGASWLKMPEFVYALFIGVIITNLTEISRGYKINSECVDVLGSVSLALFLSMALMNLKLWEIFDLAIPLLIILV
VQTAVLGLFAYFVTFKMMGSNYDAAVMAGGHCGFGLGATPTAVMNMGALVSRTGPSPQAFMVVPIVGAFFVDIVNAVILK
GFMIFVG

Sequences:

>Translated_407_residues
MNTVYTIGELESFLVAILVLFIGHTVNRHIPILKKYNIPEPIVGGLLIAALITVLHFNDITVAFSLSMQNTLMLMFFSTV
GLAANYKLLLKGGSKVFLFLGVASLFIVIQNIVGVSLANLLGLESFMGLIAGSITLSGGHGTGAAWADTFQSEYGINTLE
FAMAAATFGLVMGGIIGGPVAQRLINKNNLVSSYGVGGNHHTDHPDLVTYDQFEEDRVTAKSVLETLFIMLLCVAGAKWT
TLLIDTVGASWLKMPEFVYALFIGVIITNLTEISRGYKINSECVDVLGSVSLALFLSMALMNLKLWEIFDLAIPLLIILV
VQTAVLGLFAYFVTFKMMGSNYDAAVMAGGHCGFGLGATPTAVMNMGALVSRTGPSPQAFMVVPIVGAFFVDIVNAVILK
GFMIFVG
>Mature_407_residues
MNTVYTIGELESFLVAILVLFIGHTVNRHIPILKKYNIPEPIVGGLLIAALITVLHFNDITVAFSLSMQNTLMLMFFSTV
GLAANYKLLLKGGSKVFLFLGVASLFIVIQNIVGVSLANLLGLESFMGLIAGSITLSGGHGTGAAWADTFQSEYGINTLE
FAMAAATFGLVMGGIIGGPVAQRLINKNNLVSSYGVGGNHHTDHPDLVTYDQFEEDRVTAKSVLETLFIMLLCVAGAKWT
TLLIDTVGASWLKMPEFVYALFIGVIITNLTEISRGYKINSECVDVLGSVSLALFLSMALMNLKLWEIFDLAIPLLIILV
VQTAVLGLFAYFVTFKMMGSNYDAAVMAGGHCGFGLGATPTAVMNMGALVSRTGPSPQAFMVVPIVGAFFVDIVNAVILK
GFMIFVG

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=399, Percent_Identity=48.3709273182957, Blast_Score=301, Evalue=6e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 43531; Mature: 43531

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVYTIGELESFLVAILVLFIGHTVNRHIPILKKYNIPEPIVGGLLIAALITVLHFNDI
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCE
TVAFSLSMQNTLMLMFFSTVGLAANYKLLLKGGSKVFLFLGVASLFIVIQNIVGVSLANL
EEEEEECHHHHHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHH
LGLESFMGLIAGSITLSGGHGTGAAWADTFQSEYGINTLEFAMAAATFGLVMGGIIGGPV
HHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHH
AQRLINKNNLVSSYGVGGNHHTDHPDLVTYDQFEEDRVTAKSVLETLFIMLLCVAGAKWT
HHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
TLLIDTVGASWLKMPEFVYALFIGVIITNLTEISRGYKINSECVDVLGSVSLALFLSMAL
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
MNLKLWEIFDLAIPLLIILVVQTAVLGLFAYFVTFKMMGSNYDAAVMAGGHCGFGLGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
TAVMNMGALVSRTGPSPQAFMVVPIVGAFFVDIVNAVILKGFMIFVG
HHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTVYTIGELESFLVAILVLFIGHTVNRHIPILKKYNIPEPIVGGLLIAALITVLHFNDI
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCE
TVAFSLSMQNTLMLMFFSTVGLAANYKLLLKGGSKVFLFLGVASLFIVIQNIVGVSLANL
EEEEEECHHHHHHHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHH
LGLESFMGLIAGSITLSGGHGTGAAWADTFQSEYGINTLEFAMAAATFGLVMGGIIGGPV
HHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHH
AQRLINKNNLVSSYGVGGNHHTDHPDLVTYDQFEEDRVTAKSVLETLFIMLLCVAGAKWT
HHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
TLLIDTVGASWLKMPEFVYALFIGVIITNLTEISRGYKINSECVDVLGSVSLALFLSMAL
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
MNLKLWEIFDLAIPLLIILVVQTAVLGLFAYFVTFKMMGSNYDAAVMAGGHCGFGLGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
TAVMNMGALVSRTGPSPQAFMVVPIVGAFFVDIVNAVILKGFMIFVG
HHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]