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The map label for this gene is ltrA [H]

Identifier: 157963014

GI number: 157963014

Start: 3919563

End: 3920456

Strand: Direct

Name: ltrA [H]

Synonym: Spea_3197

Alternate gene names: 157963014

Gene position: 3919563-3920456 (Clockwise)

Preceding gene: 157963011

Following gene: 157963020

Centisome position: 75.75

GC content: 47.32

Gene sequence:

>894_bases
ATGTTAAGTGCGATGCGGATCTTCATCAAAGTGGTTGAACTAGGAAGCTTCTCCAAAGCTGCCGAAGTACTCAATATGGC
GCCATCAAGTGTCGCCCGCAATATCGACAGTCTTGAGCAAGACTTTAATGCAGTCTTGCTCAAGCGCAGCACTCGTCAGC
TATTACTCACTGAAGCCGGTGAACTCTTCTTAGAAGGTGCACGCAAGCTGGTTAATGATGAAGAGACCCTGAAAACGTCG
CTTTCAAAACGAGATAGCCAACCTGAAGGAATATTAAGGATATCGGTCTTTGAAGGATTTGGGCGGGTAAAAATCTGCCC
TATTCTGCCCGATTTCTTAGCTCAATACCCTAAAGTAAAGATTGAAATAGACTTAGATAATCAACTGGTAGATTTACACT
CAGAAAATGTGGACATTGCAATTCGCATTGGCAATGCACAAGATTCGAGTCTAAACGCCAGAATGCTGATGGCAAACCAA
ACTTCGCTCTGTGCTAGCGCTAAATACCTGGCTCAATTTGGCACTCCTAAGAAGCCTGAAGAGTTGCAGCATCATAACTG
TTTACTCCTCGACCGGGACAGGCAGCGCACCTACTGGCATTTCAAAAAGGGCAATCAATATAAGAAAGTCCCAGTGCAAG
GCAACTTAACCTCAAGAGGCGGCACGCCCATTCTAGAGGCGGCGATACATCACGGCGGCATAGTGCAACTGTCGAGTTGG
ATGATGGAAGACTTAATCCAAGATGGCAGTTTAGTGCGCTGCCTACCCGACTGGACACCCTCACTGTCAGAGCAATCCAG
TGGCGATATCTATGCGCTCTACCGCGGCGGTAAGCACATGCGGCCAGTGATCCGCGCCTTTATCGATTACTTAGTAAAGG
CGCTAAAGCGATAA

Upstream 100 bases:

>100_bases
ATTGAACAAGAGACATTATCCATAGATAGAAAAAAGCTGGAATACAGATAAAAACTGTTTTACCTTTGCGTAAAACGCAA
AGGTAAAGTTAGGACAATTC

Downstream 100 bases:

>100_bases
TATTACCCACTTTAGAACAGCAAAAAGCCGCATAACTAAATGATATGCGGCTTTTATTAGCCCTGGCGATCTTAGCTAGC
TTATGCCAAGAGCATACGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLSAMRIFIKVVELGSFSKAAEVLNMAPSSVARNIDSLEQDFNAVLLKRSTRQLLLTEAGELFLEGARKLVNDEETLKTS
LSKRDSQPEGILRISVFEGFGRVKICPILPDFLAQYPKVKIEIDLDNQLVDLHSENVDIAIRIGNAQDSSLNARMLMANQ
TSLCASAKYLAQFGTPKKPEELQHHNCLLLDRDRQRTYWHFKKGNQYKKVPVQGNLTSRGGTPILEAAIHHGGIVQLSSW
MMEDLIQDGSLVRCLPDWTPSLSEQSSGDIYALYRGGKHMRPVIRAFIDYLVKALKR

Sequences:

>Translated_297_residues
MLSAMRIFIKVVELGSFSKAAEVLNMAPSSVARNIDSLEQDFNAVLLKRSTRQLLLTEAGELFLEGARKLVNDEETLKTS
LSKRDSQPEGILRISVFEGFGRVKICPILPDFLAQYPKVKIEIDLDNQLVDLHSENVDIAIRIGNAQDSSLNARMLMANQ
TSLCASAKYLAQFGTPKKPEELQHHNCLLLDRDRQRTYWHFKKGNQYKKVPVQGNLTSRGGTPILEAAIHHGGIVQLSSW
MMEDLIQDGSLVRCLPDWTPSLSEQSSGDIYALYRGGKHMRPVIRAFIDYLVKALKR
>Mature_297_residues
MLSAMRIFIKVVELGSFSKAAEVLNMAPSSVARNIDSLEQDFNAVLLKRSTRQLLLTEAGELFLEGARKLVNDEETLKTS
LSKRDSQPEGILRISVFEGFGRVKICPILPDFLAQYPKVKIEIDLDNQLVDLHSENVDIAIRIGNAQDSSLNARMLMANQ
TSLCASAKYLAQFGTPKKPEELQHHNCLLLDRDRQRTYWHFKKGNQYKKVPVQGNLTSRGGTPILEAAIHHGGIVQLSSW
MMEDLIQDGSLVRCLPDWTPSLSEQSSGDIYALYRGGKHMRPVIRAFIDYLVKALKR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=30.9027777777778, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=32.1917808219178, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=31.0580204778157, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789639, Length=300, Percent_Identity=29.3333333333333, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=26.6211604095563, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI145693193, Length=261, Percent_Identity=29.1187739463602, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787589, Length=287, Percent_Identity=27.8745644599303, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789173, Length=251, Percent_Identity=27.8884462151394, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788706, Length=305, Percent_Identity=24.9180327868852, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790011, Length=269, Percent_Identity=24.1635687732342, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786448, Length=297, Percent_Identity=25.9259259259259, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082132, Length=296, Percent_Identity=26.3513513513513, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI157672245, Length=165, Percent_Identity=26.0606060606061, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=131, Percent_Identity=28.2442748091603, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI145693105, Length=154, Percent_Identity=25.3246753246753, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33380; Mature: 33380

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAMRIFIKVVELGSFSKAAEVLNMAPSSVARNIDSLEQDFNAVLLKRSTRQLLLTEAG
CCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELFLEGARKLVNDEETLKTSLSKRDSQPEGILRISVFEGFGRVKICPILPDFLAQYPKVK
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEECCHHHHHHCCCEE
IEIDLDNQLVDLHSENVDIAIRIGNAQDSSLNARMLMANQTSLCASAKYLAQFGTPKKPE
EEEECCCCEEEECCCCEEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCH
ELQHHNCLLLDRDRQRTYWHFKKGNQYKKVPVQGNLTSRGGTPILEAAIHHGGIVQLSSW
HHCCCCEEEEECCCCCCEEEECCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCHHHHHHH
MMEDLIQDGSLVRCLPDWTPSLSEQSSGDIYALYRGGKHMRPVIRAFIDYLVKALKR
HHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSAMRIFIKVVELGSFSKAAEVLNMAPSSVARNIDSLEQDFNAVLLKRSTRQLLLTEAG
CCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELFLEGARKLVNDEETLKTSLSKRDSQPEGILRISVFEGFGRVKICPILPDFLAQYPKVK
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEECCHHHHHHCCCEE
IEIDLDNQLVDLHSENVDIAIRIGNAQDSSLNARMLMANQTSLCASAKYLAQFGTPKKPE
EEEECCCCEEEECCCCEEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCH
ELQHHNCLLLDRDRQRTYWHFKKGNQYKKVPVQGNLTSRGGTPILEAAIHHGGIVQLSSW
HHCCCCEEEEECCCCCCEEEECCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCHHHHHHH
MMEDLIQDGSLVRCLPDWTPSLSEQSSGDIYALYRGGKHMRPVIRAFIDYLVKALKR
HHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]