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The map label for this gene is mrdB [H]

Identifier: 157962967

GI number: 157962967

Start: 3855460

End: 3856566

Strand: Direct

Name: mrdB [H]

Synonym: Spea_3150

Alternate gene names: 157962967

Gene position: 3855460-3856566 (Clockwise)

Preceding gene: 157962966

Following gene: 157962968

Centisome position: 74.51

GC content: 48.33

Gene sequence:

>1107_bases
ATGAGTGCACACAATCACCGCCCAAATATCTGGCAGCGTCTACACATAGACCTACCTCTGCTGTTAGGCCTTTTAGCACT
AATGGCCTTTGGTCTAGTCGTTATCTACTCGGCCGGTGGTGAAGACTTAGCCCTGATGGACAGACAACTGTTTCGCATGG
GCTTGTCGCTATTAGTGATGTTTACCGTGGCACAGATAAACCCGGAAGTACTCAGACGCTGGGCCTTCCCCATCTATCTA
GCCGGAATCGTTTTGCTGATAGGTGTGCATTTTTTTGGTGAGATCAATAAGGGCGCTCAGCGCTGGCTAAACCTTGGATT
TATGGAGTTTCAGCCATCTGAGCTGATTAAGCTCGCCTTCCCAATCACCATGGCTTGGTACATTAGTAAGTTCCCTTTGC
CGCCAAAGAAACGCTACCTCGCGGGCGCTGGCGTCATCTTACTGGTACCTACCCTACTTATCGCTAAACAACCAGATCTA
GGGACCTCGATTCTCGTTGCAGCATCTGGGATCTTCGTGCTGTTTTTATCCGGTATGAGCTGGCGCATTGTGGGTGGTTT
TATCGGTAGTGCGTTAGCAATGTTGCCCGTACTCTGGTTCTTCTTGATGCACGATTATCAGCGTACTAGAGTGCTCACTC
TACTTGACCCAGAGAAAGATCCTCTCGGTGCTGGCTACCATATTATTCAGTCCAAGATTGCCATCGGTTCCGGCGGTTTA
TGGGGTAAAGGCTGGCTGCAAGGCACGCAGTCACAACTCGAATTCTTGCCCGAACGCCATACCGACTTTATCTTCGCCGT
TATTGGTGAAGAGTTTGGCCTCATTGGTGCTTTATTACTACTGTCACTCTATATCTACGTCATTGGCCGCGGATTAGTTA
TTGCCTCCCGCGCACAAACCAGCTTTGCCCGCTTGCTTGCCGGCAGTATTACCCTAACCTTCTTCGTGTATATTTTTGTT
AATATCGGTATGGTTTCAGGGCTTTTACCCGTAGTGGGTGTACCTCTGCCACTAATCAGTTATGGTGGTACCTCGATGCT
GACATTGATGACAGGTTTTGGCATCTTAATGAGTATTCATACCCATAGACGCTTTATTGATAGATAG

Upstream 100 bases:

>100_bases
TCGTACTTGAGAATGCTGGTTGGGGCGGTGTAAACGCAGGCCCCGTAGCTCGCGCCTTGTTAGACGAGTATTTATTAAGA
GATTCATGGGATAAGACTAA

Downstream 100 bases:

>100_bases
CGACTAGTTCAAGCCATTTGATAATTAATCCTCGGAAGCATTATGGTGCATTCAAATCGCCTAACCATGATGCCTATAGA
CCACTAAGGACTGCACAATA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSAHNHRPNIWQRLHIDLPLLLGLLALMAFGLVVIYSAGGEDLALMDRQLFRMGLSLLVMFTVAQINPEVLRRWAFPIYL
AGIVLLIGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWYISKFPLPPKKRYLAGAGVILLVPTLLIAKQPDL
GTSILVAASGIFVLFLSGMSWRIVGGFIGSALAMLPVLWFFLMHDYQRTRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGL
WGKGWLQGTQSQLEFLPERHTDFIFAVIGEEFGLIGALLLLSLYIYVIGRGLVIASRAQTSFARLLAGSITLTFFVYIFV
NIGMVSGLLPVVGVPLPLISYGGTSMLTLMTGFGILMSIHTHRRFIDR

Sequences:

>Translated_368_residues
MSAHNHRPNIWQRLHIDLPLLLGLLALMAFGLVVIYSAGGEDLALMDRQLFRMGLSLLVMFTVAQINPEVLRRWAFPIYL
AGIVLLIGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWYISKFPLPPKKRYLAGAGVILLVPTLLIAKQPDL
GTSILVAASGIFVLFLSGMSWRIVGGFIGSALAMLPVLWFFLMHDYQRTRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGL
WGKGWLQGTQSQLEFLPERHTDFIFAVIGEEFGLIGALLLLSLYIYVIGRGLVIASRAQTSFARLLAGSITLTFFVYIFV
NIGMVSGLLPVVGVPLPLISYGGTSMLTLMTGFGILMSIHTHRRFIDR
>Mature_367_residues
SAHNHRPNIWQRLHIDLPLLLGLLALMAFGLVVIYSAGGEDLALMDRQLFRMGLSLLVMFTVAQINPEVLRRWAFPIYLA
GIVLLIGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAFPITMAWYISKFPLPPKKRYLAGAGVILLVPTLLIAKQPDLG
TSILVAASGIFVLFLSGMSWRIVGGFIGSALAMLPVLWFFLMHDYQRTRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGLW
GKGWLQGTQSQLEFLPERHTDFIFAVIGEEFGLIGALLLLSLYIYVIGRGLVIASRAQTSFARLLAGSITLTFFVYIFVN
IGMVSGLLPVVGVPLPLISYGGTSMLTLMTGFGILMSIHTHRRFIDR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=368, Percent_Identity=59.2391304347826, Blast_Score=416, Evalue=1e-118,
Organism=Escherichia coli, GI1786277, Length=364, Percent_Identity=36.2637362637363, Blast_Score=174, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40714; Mature: 40583

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHNHRPNIWQRLHIDLPLLLGLLALMAFGLVVIYSAGGEDLALMDRQLFRMGLSLLVM
CCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHH
FTVAQINPEVLRRWAFPIYLAGIVLLIGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECHHHHHHHHH
PITMAWYISKFPLPPKKRYLAGAGVILLVPTLLIAKQPDLGTSILVAASGIFVLFLSGMS
HHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
WRIVGGFIGSALAMLPVLWFFLMHDYQRTRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHEECCCCC
WGKGWLQGTQSQLEFLPERHTDFIFAVIGEEFGLIGALLLLSLYIYVIGRGLVIASRAQT
CCCHHHCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHH
SFARLLAGSITLTFFVYIFVNIGMVSGLLPVVGVPLPLISYGGTSMLTLMTGFGILMSIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHH
THRRFIDR
HHHHHHCC
>Mature Secondary Structure 
SAHNHRPNIWQRLHIDLPLLLGLLALMAFGLVVIYSAGGEDLALMDRQLFRMGLSLLVM
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHH
FTVAQINPEVLRRWAFPIYLAGIVLLIGVHFFGEINKGAQRWLNLGFMEFQPSELIKLAF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECHHHHHHHHH
PITMAWYISKFPLPPKKRYLAGAGVILLVPTLLIAKQPDLGTSILVAASGIFVLFLSGMS
HHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
WRIVGGFIGSALAMLPVLWFFLMHDYQRTRVLTLLDPEKDPLGAGYHIIQSKIAIGSGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHEECCCCC
WGKGWLQGTQSQLEFLPERHTDFIFAVIGEEFGLIGALLLLSLYIYVIGRGLVIASRAQT
CCCHHHCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHH
SFARLLAGSITLTFFVYIFVNIGMVSGLLPVVGVPLPLISYGGTSMLTLMTGFGILMSIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHH
THRRFIDR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]