Click here to switch to the map view.

The map label for this gene is ipk [H]

Identifier: 157962946

GI number: 157962946

Start: 3832224

End: 3833078

Strand: Direct

Name: ipk [H]

Synonym: Spea_3129

Alternate gene names: 157962946

Gene position: 3832224-3833078 (Clockwise)

Preceding gene: 157962945

Following gene: 157962947

Centisome position: 74.06

GC content: 46.78

Gene sequence:

>855_bases
ATGACAGCGTCACTTTCATTAGGCTGGCCGGCTCCGGCTAAACTAAACCTATTTCTACATATCAACGCTCAGCGTCATGA
CGGCTATCACGAACTGCAAACTCTGTTTCAGTTTATCGAACATTGTGACTATCTAGACTTCAAAGTGTTAGATACGCCAA
AGCTGAAATTACATTCGAATATGTCATCAGCTGTTGCCGACAGCGATAACTTAATTCTCAAAGCCGCAAAATCGCTGCAA
CAACGAACAGATTGTCAGCTAGGGGCTGAAATTTGGCTAGATAAACGCCTTCCTATGGGCGGCGGTCTCGGCGGCGGTTC
CTCCGACGCAGCCACCACGCTAGTCGCACTTAATCAACTATGGGAAACAGGATTGTCGCTACGAGAGCTCGGTGAAATAG
GCTTAAAGCTTGGCGCAGATGTTCCTGTTTTTATTAATGGTTTTTCAGCATTTGCCGAAGGTGTAGGCGAAAAATTGCAA
AACGTTGAGCCCGCCGAGCCTTGGTATCTGGTGTTGACTCCCCAAGTACATGTTTCTACGGCTGAAGTCTTTCAAGACCC
AGACCTACCTCGAAACACGCCAAAGTTAAGTCTCGAGTCATTGATGAACAGCCCATGGCAAAATGACTGCCAAACATTAG
TCGCAAAACGCTACCCTCAAGTTGCCAAAACCTTAGCGTGGCTGCTAGAATATGCGCCGTCCAGAATGACCGGAACAGGA
GCATGTGTTTTTGGTCAATTCGAACAGGAGCAAGAAGCTAAAGATGTATTGGCGAAGTTGCCTGCATCGATACAAGGCTT
TGTTGCGAAAGGGGCAAATATATCACCGTTGATGCTGAGATTAGCTCAGTGTTAA

Upstream 100 bases:

>100_bases
GTGGTGAGATTCGCCTAAAATTACAGCTGAGTCAGTGGCAAGCTTTAGCACCACAAAGCCAAACGCTTTTCCAACAGACG
TCACCAACTGAGAACTCTTT

Downstream 100 bases:

>100_bases
CCACATTCTGGGATATTTTTAAATCCCAGCCACAATCATGAAGCATACGCCTGAGGTTCCTACAGTGCCTGACATTAAAC
TTTTTGCCGGTAACGCTACA

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTASLSLGWPAPAKLNLFLHINAQRHDGYHELQTLFQFIEHCDYLDFKVLDTPKLKLHSNMSSAVADSDNLILKAAKSLQ
QRTDCQLGAEIWLDKRLPMGGGLGGGSSDAATTLVALNQLWETGLSLRELGEIGLKLGADVPVFINGFSAFAEGVGEKLQ
NVEPAEPWYLVLTPQVHVSTAEVFQDPDLPRNTPKLSLESLMNSPWQNDCQTLVAKRYPQVAKTLAWLLEYAPSRMTGTG
ACVFGQFEQEQEAKDVLAKLPASIQGFVAKGANISPLMLRLAQC

Sequences:

>Translated_284_residues
MTASLSLGWPAPAKLNLFLHINAQRHDGYHELQTLFQFIEHCDYLDFKVLDTPKLKLHSNMSSAVADSDNLILKAAKSLQ
QRTDCQLGAEIWLDKRLPMGGGLGGGSSDAATTLVALNQLWETGLSLRELGEIGLKLGADVPVFINGFSAFAEGVGEKLQ
NVEPAEPWYLVLTPQVHVSTAEVFQDPDLPRNTPKLSLESLMNSPWQNDCQTLVAKRYPQVAKTLAWLLEYAPSRMTGTG
ACVFGQFEQEQEAKDVLAKLPASIQGFVAKGANISPLMLRLAQC
>Mature_283_residues
TASLSLGWPAPAKLNLFLHINAQRHDGYHELQTLFQFIEHCDYLDFKVLDTPKLKLHSNMSSAVADSDNLILKAAKSLQQ
RTDCQLGAEIWLDKRLPMGGGLGGGSSDAATTLVALNQLWETGLSLRELGEIGLKLGADVPVFINGFSAFAEGVGEKLQN
VEPAEPWYLVLTPQVHVSTAEVFQDPDLPRNTPKLSLESLMNSPWQNDCQTLVAKRYPQVAKTLAWLLEYAPSRMTGTGA
CVFGQFEQEQEAKDVLAKLPASIQGFVAKGANISPLMLRLAQC

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=275, Percent_Identity=56.3636363636364, Blast_Score=298, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 31076; Mature: 30945

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASLSLGWPAPAKLNLFLHINAQRHDGYHELQTLFQFIEHCDYLDFKVLDTPKLKLHSN
CCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHCC
MSSAVADSDNLILKAAKSLQQRTDCQLGAEIWLDKRLPMGGGLGGGSSDAATTLVALNQL
CHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHH
WETGLSLRELGEIGLKLGADVPVFINGFSAFAEGVGEKLQNVEPAEPWYLVLTPQVHVST
HHCCCCHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCEECCH
AEVFQDPDLPRNTPKLSLESLMNSPWQNDCQTLVAKRYPQVAKTLAWLLEYAPSRMTGTG
HHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCC
ACVFGQFEQEQEAKDVLAKLPASIQGFVAKGANISPLMLRLAQC
EEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure 
TASLSLGWPAPAKLNLFLHINAQRHDGYHELQTLFQFIEHCDYLDFKVLDTPKLKLHSN
CCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHCC
MSSAVADSDNLILKAAKSLQQRTDCQLGAEIWLDKRLPMGGGLGGGSSDAATTLVALNQL
CHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHH
WETGLSLRELGEIGLKLGADVPVFINGFSAFAEGVGEKLQNVEPAEPWYLVLTPQVHVST
HHCCCCHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCEECCH
AEVFQDPDLPRNTPKLSLESLMNSPWQNDCQTLVAKRYPQVAKTLAWLLEYAPSRMTGTG
HHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCC
ACVFGQFEQEQEAKDVLAKLPASIQGFVAKGANISPLMLRLAQC
EEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA