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The map label for this gene is aer [H]

Identifier: 157962841

GI number: 157962841

Start: 3705427

End: 3706971

Strand: Direct

Name: aer [H]

Synonym: Spea_3023

Alternate gene names: 157962841

Gene position: 3705427-3706971 (Clockwise)

Preceding gene: 157962839

Following gene: 157962842

Centisome position: 71.61

GC content: 45.31

Gene sequence:

>1545_bases
ATGACAAACAACCAAGCAAACTTAAGCAATCAAGAAGTTAAGTTAATCCCTAGCGATCAACTCATCTCCACCACGGATAG
GCGTGGCGTGATCACCTACGTTAACCAAAGGTTTATTGAAGTATCAGGTTTCGAGCAAGCAGAACTGATTGGACATAATC
ACAATATAGTACGTCATCCAGATATGCCCAAGGCCGCATTTGAAGAGATGTGGGGCAAACTAAAACTAGGGCTTTCTTGG
CGCGGAGTGGTCAAGAATCGTTGTAAAGACGGCAAGTACTATTGGGTCGATGCCTTCGTCTCGCCCCTGTTTGAAAGAGG
TGAGCTCATCGGGTATCAATCAGTCCGCATGGCTGCAAGCCCTCAACTCACCGATAAAGCCTCTAAAGTCTACCAGCGCC
TAAATCAGGGTAAACGTGTTGATGATCCCATCAGCTTAGCCAATAAAAGATTGTTGTCAGCAATTTGTGTCTGCACTGGG
CTATTGATTGCTGGTGCGATATGGGGATGGACAGTCATCATTGCTGGCATCATTCTAATGGGGATCAATCTTGCCATCTT
TTACGATGAAGCTTTTCGAGTGCCTGAAAAACTGATGAGAATGAAGCAAAAATATGACTCGGTCAGTCGCTTTATCTATT
GTGGGCGCGATACCTCTTCTCTATTAGATTTCCAGTTAATGATGAAAGACGCCAAGCTACAAGGGGTACTTGGACGCTCC
CAAGATAATGCCGAGCATATTGAAGATATTGCCAACCAACTGATTGCCGCTACAGAGCAAACCCATACTGGCTTAAACAT
TGAAAAACAACAGATAGAGCAGATGGCCAGTGCCACCGAAGAGATGGGAACCACCATCAGCGAAGTCGCTAGAAACACCC
AATCCACCTCAGACAGCATTCAACATAGCTATCAGTTTTGCCAAGAGAGTCGTGAGAAAATGCAGCAAAATGCCGCAGGT
ATTCATCAGCTGTCAGATTCTGTTGCCGAAGCCGCAGCTAACGCACTCTTACTGAATAAAGAGGCCGAGCGAGTCGCCAG
CGCGATGTCAGAAATCGATTCAATTGCCGAGCAAACCAACTTGCTCGCACTCAATGCAGCTATCGAAGCCGCTCGAGCTG
GAGAGCAAGGACGAGGGTTTGCGGTTGTCGCCGATGAAGTAAGAGCACTATCGAGCCGTACTCAGCAATCAACCACTAGC
ATTTCTGAGAGTGTTGATAAAATGTTTAGCATGCTCACGCTCTGGTCTAAGCAGATGAATCACAGTAAATCCCAAGCATT
ATTATGCAGCAAAGATGCCGAAATCTCCGTACAAAAGGTGGATACCATCTATCAATCGATGAAGAATATTCAACAATTAG
CCATCCAAAATGCGGTTGCGGCAGAACAACAAACCTTAGTTGTGGCCGAGATAAACCAAAATATCAGTCAAATTAGCCAA
GCATCGAGTGAGAATCTATGCGCCGTGAACTCGGTTGAGGCCTCAGTGAAGCAGTTAATAATTAATGCAGAGAAAGCAAA
ATCTTTGAGGAAAACATTTAGTTAA

Upstream 100 bases:

>100_bases
ACCACAATGTAAACAACTGTATTAATGTTATATTATATGAGCTTGTGTTAATGCGTTGCGAGCAAATCGCAATACTTTGC
TGTCACACGGAATAATAATA

Downstream 100 bases:

>100_bases
TTCCTCTTTTAAAGTCCTTTTGGTCGTTACGCAGTCTGCGTGGCGACCAAAACCAACACCAAGCACGCAACAGCAACCCA
ACATTTATAAACATCTGTTT

Product: Pas/Pac sensor containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MTNNQANLSNQEVKLIPSDQLISTTDRRGVITYVNQRFIEVSGFEQAELIGHNHNIVRHPDMPKAAFEEMWGKLKLGLSW
RGVVKNRCKDGKYYWVDAFVSPLFERGELIGYQSVRMAASPQLTDKASKVYQRLNQGKRVDDPISLANKRLLSAICVCTG
LLIAGAIWGWTVIIAGIILMGINLAIFYDEAFRVPEKLMRMKQKYDSVSRFIYCGRDTSSLLDFQLMMKDAKLQGVLGRS
QDNAEHIEDIANQLIAATEQTHTGLNIEKQQIEQMASATEEMGTTISEVARNTQSTSDSIQHSYQFCQESREKMQQNAAG
IHQLSDSVAEAAANALLLNKEAERVASAMSEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQQSTTS
ISESVDKMFSMLTLWSKQMNHSKSQALLCSKDAEISVQKVDTIYQSMKNIQQLAIQNAVAAEQQTLVVAEINQNISQISQ
ASSENLCAVNSVEASVKQLIINAEKAKSLRKTFS

Sequences:

>Translated_514_residues
MTNNQANLSNQEVKLIPSDQLISTTDRRGVITYVNQRFIEVSGFEQAELIGHNHNIVRHPDMPKAAFEEMWGKLKLGLSW
RGVVKNRCKDGKYYWVDAFVSPLFERGELIGYQSVRMAASPQLTDKASKVYQRLNQGKRVDDPISLANKRLLSAICVCTG
LLIAGAIWGWTVIIAGIILMGINLAIFYDEAFRVPEKLMRMKQKYDSVSRFIYCGRDTSSLLDFQLMMKDAKLQGVLGRS
QDNAEHIEDIANQLIAATEQTHTGLNIEKQQIEQMASATEEMGTTISEVARNTQSTSDSIQHSYQFCQESREKMQQNAAG
IHQLSDSVAEAAANALLLNKEAERVASAMSEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQQSTTS
ISESVDKMFSMLTLWSKQMNHSKSQALLCSKDAEISVQKVDTIYQSMKNIQQLAIQNAVAAEQQTLVVAEINQNISQISQ
ASSENLCAVNSVEASVKQLIINAEKAKSLRKTFS
>Mature_513_residues
TNNQANLSNQEVKLIPSDQLISTTDRRGVITYVNQRFIEVSGFEQAELIGHNHNIVRHPDMPKAAFEEMWGKLKLGLSWR
GVVKNRCKDGKYYWVDAFVSPLFERGELIGYQSVRMAASPQLTDKASKVYQRLNQGKRVDDPISLANKRLLSAICVCTGL
LIAGAIWGWTVIIAGIILMGINLAIFYDEAFRVPEKLMRMKQKYDSVSRFIYCGRDTSSLLDFQLMMKDAKLQGVLGRSQ
DNAEHIEDIANQLIAATEQTHTGLNIEKQQIEQMASATEEMGTTISEVARNTQSTSDSIQHSYQFCQESREKMQQNAAGI
HQLSDSVAEAAANALLLNKEAERVASAMSEIDSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQQSTTSI
SESVDKMFSMLTLWSKQMNHSKSQALLCSKDAEISVQKVDTIYQSMKNIQQLAIQNAVAAEQQTLVVAEINQNISQISQA
SSENLCAVNSVEASVKQLIINAEKAKSLRKTFS

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=498, Percent_Identity=29.3172690763052, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1788195, Length=160, Percent_Identity=35.625, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787690, Length=227, Percent_Identity=28.1938325991189, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788194, Length=242, Percent_Identity=28.9256198347107, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI2367378, Length=244, Percent_Identity=30.327868852459, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 56926; Mature: 56795

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNQANLSNQEVKLIPSDQLISTTDRRGVITYVNQRFIEVSGFEQAELIGHNHNIVRHP
CCCCCCCCCCCCEEECCCCCHHCCCCCCCHHHHHHHHHEEECCCCHHHHHCCCCCCCCCC
DMPKAAFEEMWGKLKLGLSWRGVVKNRCKDGKYYWVDAFVSPLFERGELIGYQSVRMAAS
CCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHCCC
PQLTDKASKVYQRLNQGKRVDDPISLANKRLLSAICVCTGLLIAGAIWGWTVIIAGIILM
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GINLAIFYDEAFRVPEKLMRMKQKYDSVSRFIYCGRDTSSLLDFQLMMKDAKLQGVLGRS
HHHHEEEEHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
QDNAEHIEDIANQLIAATEQTHTGLNIEKQQIEQMASATEEMGTTISEVARNTQSTSDSI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHH
QHSYQFCQESREKMQQNAAGIHQLSDSVAEAAANALLLNKEAERVASAMSEIDSIAEQTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQQSTTSISESVDKMFSMLTLWSKQMN
HHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HSKSQALLCSKDAEISVQKVDTIYQSMKNIQQLAIQNAVAAEQQTLVVAEINQNISQISQ
CCHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHH
ASSENLCAVNSVEASVKQLIINAEKAKSLRKTFS
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNNQANLSNQEVKLIPSDQLISTTDRRGVITYVNQRFIEVSGFEQAELIGHNHNIVRHP
CCCCCCCCCCCEEECCCCCHHCCCCCCCHHHHHHHHHEEECCCCHHHHHCCCCCCCCCC
DMPKAAFEEMWGKLKLGLSWRGVVKNRCKDGKYYWVDAFVSPLFERGELIGYQSVRMAAS
CCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHCCC
PQLTDKASKVYQRLNQGKRVDDPISLANKRLLSAICVCTGLLIAGAIWGWTVIIAGIILM
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GINLAIFYDEAFRVPEKLMRMKQKYDSVSRFIYCGRDTSSLLDFQLMMKDAKLQGVLGRS
HHHHEEEEHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
QDNAEHIEDIANQLIAATEQTHTGLNIEKQQIEQMASATEEMGTTISEVARNTQSTSDSI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHH
QHSYQFCQESREKMQQNAAGIHQLSDSVAEAAANALLLNKEAERVASAMSEIDSIAEQTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLALNAAIEAARAGEQGRGFAVVADEVRALSSRTQQSTTSISESVDKMFSMLTLWSKQMN
HHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HSKSQALLCSKDAEISVQKVDTIYQSMKNIQQLAIQNAVAAEQQTLVVAEINQNISQISQ
CCHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHH
ASSENLCAVNSVEASVKQLIINAEKAKSLRKTFS
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]