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The map label for this gene is gpo [H]

Identifier: 157962782

GI number: 157962782

Start: 3628609

End: 3629091

Strand: Direct

Name: gpo [H]

Synonym: Spea_2964

Alternate gene names: 157962782

Gene position: 3628609-3629091 (Clockwise)

Preceding gene: 157962781

Following gene: 157962784

Centisome position: 70.12

GC content: 41.41

Gene sequence:

>483_bases
ATGACAGCTTCCATTTACGATTTTTCAGTTAACAATATTCAGGGAAAAACGGTTTCACTGGCGAACTTTAAAGACAAAGT
CATATTGATTGTTAATACAGCCAGCGAATGTGGCTTTACGCCTCAATATAAGGAGCTTGAGGCTCTGTACCAAAAACACC
AGTCTCAAGGGCTGGCGGTGCTTGGGTTTCCATGTAACCAGTTTGGCGAGCAAGAAAAAGGGGATAACCAAGCCATTAGC
TCATTTTGTGAATTAAATTTTGGTGTGACCTTCCCACTATTTGAAAAAATTGAAGTAAATGGCGCCAATACCGCTCCACT
GTATGCACATTTAAAGCAATCTGCTAAAGGCTTACTGGGTTCTGAAGCAATAAAGTGGAACTTTACCAAGTTTTTAGTCG
ATAGGCAGGGCAAAGTCACCCAACGCTTTGCGCCAACGACGAAGCCAATGGCAATTGAAGGTGAAATATTAAAGCTACTT
TAG

Upstream 100 bases:

>100_bases
AACCGCCCCCTCCCGCTGTAAGCTAACGCCGCCAACAAAAACTCTGCACAAACCCATAAAATACCGTTAGAGTATCCCTA
GCTAAACAAAGGGGGAAATG

Downstream 100 bases:

>100_bases
TCATTAAAATGAATAACTTAAAATCACCTTTTAAAAAGATCATATATTCTGGATTCTTTTTTGAACTTTATCACAATACT
CATCTCTAACTTCTTGAGCA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTASIYDFSVNNIQGKTVSLANFKDKVILIVNTASECGFTPQYKELEALYQKHQSQGLAVLGFPCNQFGEQEKGDNQAIS
SFCELNFGVTFPLFEKIEVNGANTAPLYAHLKQSAKGLLGSEAIKWNFTKFLVDRQGKVTQRFAPTTKPMAIEGEILKLL

Sequences:

>Translated_160_residues
MTASIYDFSVNNIQGKTVSLANFKDKVILIVNTASECGFTPQYKELEALYQKHQSQGLAVLGFPCNQFGEQEKGDNQAIS
SFCELNFGVTFPLFEKIEVNGANTAPLYAHLKQSAKGLLGSEAIKWNFTKFLVDRQGKVTQRFAPTTKPMAIEGEILKLL
>Mature_159_residues
TASIYDFSVNNIQGKTVSLANFKDKVILIVNTASECGFTPQYKELEALYQKHQSQGLAVLGFPCNQFGEQEKGDNQAISS
FCELNFGVTFPLFEKIEVNGANTAPLYAHLKQSAKGLLGSEAIKWNFTKFLVDRQGKVTQRFAPTTKPMAIEGEILKLL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=41.6666666666667, Blast_Score=127, Evalue=5e-30,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=41.6666666666667, Blast_Score=126, Evalue=6e-30,
Organism=Homo sapiens, GI15618997, Length=156, Percent_Identity=42.3076923076923, Blast_Score=123, Evalue=7e-29,
Organism=Homo sapiens, GI192455698, Length=158, Percent_Identity=38.6075949367089, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=42.7480916030534, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI4557629, Length=178, Percent_Identity=36.5168539325843, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI41406084, Length=182, Percent_Identity=36.2637362637363, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI6006001, Length=180, Percent_Identity=35, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI32967607, Length=187, Percent_Identity=32.620320855615, Blast_Score=88, Evalue=2e-18,
Organism=Homo sapiens, GI33186887, Length=180, Percent_Identity=33.8888888888889, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI1788003, Length=168, Percent_Identity=43.452380952381, Blast_Score=144, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17535473, Length=158, Percent_Identity=50, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17506887, Length=159, Percent_Identity=46.5408805031447, Blast_Score=142, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI193210707, Length=164, Percent_Identity=48.1707317073171, Blast_Score=139, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71993584, Length=162, Percent_Identity=40.7407407407407, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17550320, Length=164, Percent_Identity=35.9756097560976, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=170, Percent_Identity=34.1176470588235, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI193210709, Length=76, Percent_Identity=51.3157894736842, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=38.1578947368421, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71993573, Length=100, Percent_Identity=36, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=55.625, Blast_Score=197, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6322228, Length=158, Percent_Identity=50.6329113924051, Blast_Score=182, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=48.3870967741936, Blast_Score=159, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=48.125, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=48.125, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=48.125, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=38.9937106918239, Blast_Score=109, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17714; Mature: 17583

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASIYDFSVNNIQGKTVSLANFKDKVILIVNTASECGFTPQYKELEALYQKHQSQGLAV
CCCEEEEEECCCCCCCEEEECCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHCCCCEE
LGFPCNQFGEQEKGDNQAISSFCELNFGVTFPLFEKIEVNGANTAPLYAHLKQSAKGLLG
EECCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCC
SEAIKWNFTKFLVDRQGKVTQRFAPTTKPMAIEGEILKLL
CCCEEECHHEEEECCCCCCHHHCCCCCCCEEECCCCEECC
>Mature Secondary Structure 
TASIYDFSVNNIQGKTVSLANFKDKVILIVNTASECGFTPQYKELEALYQKHQSQGLAV
CCEEEEEECCCCCCCEEEECCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHCCCCEE
LGFPCNQFGEQEKGDNQAISSFCELNFGVTFPLFEKIEVNGANTAPLYAHLKQSAKGLLG
EECCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCC
SEAIKWNFTKFLVDRQGKVTQRFAPTTKPMAIEGEILKLL
CCCEEECHHEEEECCCCCCHHHCCCCCCCEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]