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The map label for this gene is cat [H]

Identifier: 157962680

GI number: 157962680

Start: 3493843

End: 3494472

Strand: Direct

Name: cat [H]

Synonym: Spea_2861

Alternate gene names: 157962680

Gene position: 3493843-3494472 (Clockwise)

Preceding gene: 157962679

Following gene: 157962681

Centisome position: 67.52

GC content: 49.52

Gene sequence:

>630_bases
ATGGAAAAGCCAGCAGTAACTAAGCCCGATTACCGAACTCAGCATCAAAAGCGCTTGTCTTACATGCCTTGGCTTTATTT
CTCACTAAAAGAGAAACATCTTCAGTGGGCCAAGCCATGGCAAGCTGAAGTGCAAGCTCATTTTAGTGCGGTAGAAACCA
TCTCTATTGGCGATAACTGTTTCGTGGCGCCAGAGGCGAACCTTTTTGCAGAGCCTGGACGTGATATCAATATCGGCAAT
CAATGTATGATAGCCGCTGACAGCTTCTTGCACGGCCCTATTACATTAGGCAATGAAGTGGCGATTAATCACGGTTGCTC
CCTCGATGGTGGCCGTCACGGGATCAAGATAGGCAATCAAACCCGCATCGCTAATAACGTTACCATCTACGCCTTTAATC
ACGGTATGGCGCCCGATACCCCAATCTATCAACAAGCCTCTAACTCCAAAGGTGTGGTGATAGGGGAAGACGTATGGATT
GGCGCTCAAGCGGGGATTGTGGATGGTGTCACCATAGGTAATCACGCCGTAATAGGCATGGGGGCCGTGGTGACCAAAGA
TGTGGCCGACTACGCGATTGTGGCGGGTAATCCAGCTCGAGTAATTGGCGATAGACGAGAAAAGCGCTAA

Upstream 100 bases:

>100_bases
AAGGTATTGAAGTCACTGAACTGCGCCCGTCAACGATTGGTAAAGATTTACCGTCTGCTCCGCAATCAGTTCAGCCAACA
TCGCAGAGTTAAGCAAACCT

Downstream 100 bases:

>100_bases
CAGCGTCACTCTCGTTAAATTTCAAATCTACCAATGTGAAAGTATAAAAGTGACTATCGATTTAAATCACTTTCAATTTA
GGTCACTTTATGCTCTTTTC

Product: hexapaptide repeat-containing transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MEKPAVTKPDYRTQHQKRLSYMPWLYFSLKEKHLQWAKPWQAEVQAHFSAVETISIGDNCFVAPEANLFAEPGRDINIGN
QCMIAADSFLHGPITLGNEVAINHGCSLDGGRHGIKIGNQTRIANNVTIYAFNHGMAPDTPIYQQASNSKGVVIGEDVWI
GAQAGIVDGVTIGNHAVIGMGAVVTKDVADYAIVAGNPARVIGDRREKR

Sequences:

>Translated_209_residues
MEKPAVTKPDYRTQHQKRLSYMPWLYFSLKEKHLQWAKPWQAEVQAHFSAVETISIGDNCFVAPEANLFAEPGRDINIGN
QCMIAADSFLHGPITLGNEVAINHGCSLDGGRHGIKIGNQTRIANNVTIYAFNHGMAPDTPIYQQASNSKGVVIGEDVWI
GAQAGIVDGVTIGNHAVIGMGAVVTKDVADYAIVAGNPARVIGDRREKR
>Mature_209_residues
MEKPAVTKPDYRTQHQKRLSYMPWLYFSLKEKHLQWAKPWQAEVQAHFSAVETISIGDNCFVAPEANLFAEPGRDINIGN
QCMIAADSFLHGPITLGNEVAINHGCSLDGGRHGIKIGNQTRIANNVTIYAFNHGMAPDTPIYQQASNSKGVVIGEDVWI
GAQAGIVDGVTIGNHAVIGMGAVVTKDVADYAIVAGNPARVIGDRREKR

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=112, Percent_Identity=45.5357142857143, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786537, Length=186, Percent_Identity=27.9569892473118, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788345, Length=130, Percent_Identity=31.5384615384615, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322243, Length=116, Percent_Identity=37.0689655172414, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 22719; Mature: 22719

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKPAVTKPDYRTQHQKRLSYMPWLYFSLKEKHLQWAKPWQAEVQAHFSAVETISIGDNC
CCCCCCCCCCCHHHHHHHHCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHEEEEEEECCCE
FVAPEANLFAEPGRDINIGNQCMIAADSFLHGPITLGNEVAINHGCSLDGGRHGIKIGNQ
EECCCCCEEECCCCCCCCCCEEEEEECCCCCCCEECCCEEEEECCCCCCCCCCCEEECCC
TRIANNVTIYAFNHGMAPDTPIYQQASNSKGVVIGEDVWIGAQAGIVDGVTIGNHAVIGM
EEEECCEEEEEEECCCCCCCCHHHCCCCCCCEEEECCEEECCCCCCCCCEEECCEEEEEC
GAVVTKDVADYAIVAGNPARVIGDRREKR
CHHHHHCCCCEEEECCCCHHEECCCCCCC
>Mature Secondary Structure
MEKPAVTKPDYRTQHQKRLSYMPWLYFSLKEKHLQWAKPWQAEVQAHFSAVETISIGDNC
CCCCCCCCCCCHHHHHHHHCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHEEEEEEECCCE
FVAPEANLFAEPGRDINIGNQCMIAADSFLHGPITLGNEVAINHGCSLDGGRHGIKIGNQ
EECCCCCEEECCCCCCCCCCEEEEEECCCCCCCEECCCEEEEECCCCCCCCCCCEEECCC
TRIANNVTIYAFNHGMAPDTPIYQQASNSKGVVIGEDVWIGAQAGIVDGVTIGNHAVIGM
EEEECCEEEEEEECCCCCCCCHHHCCCCCCCEEEECCEEECCCCCCCCCEEECCEEEEEC
GAVVTKDVADYAIVAGNPARVIGDRREKR
CHHHHHCCCCEEEECCCCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2013403; 11743193; 11743194 [H]