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The map label for this gene is dppA [H]

Identifier: 157962492

GI number: 157962492

Start: 3253779

End: 3255407

Strand: Direct

Name: dppA [H]

Synonym: Spea_2671

Alternate gene names: 157962492

Gene position: 3253779-3255407 (Clockwise)

Preceding gene: 157962491

Following gene: 157962493

Centisome position: 62.88

GC content: 45.0

Gene sequence:

>1629_bases
ATGAAACAGCTGCTTAAGAGAATAAAGTTAATCGCTGGGATCTCTTTGATTAACTTGTTACTCACCGCCTGTGGTCCACA
GCAAGTTCCGACAGGGTTAGTCTATTGTTCGGAAGGCAACCCTGAGACTTTTAATCCTCAATTGGTGACCTCTGGCACCA
CGATTGATGCCACCTCACAGCAGTTATACGACAGTTTAGTCGATTACGACCCGGTATCTGGTGAAATAGTGCCTGCGCTC
GCCACTTCTTGGGAGACTTCTGCTGACGGTCTAAGCTACCGCTTTAAATTGCGCCATGGGGTACAGTTCCATCAAACATC
GCTATTTAGCCCGACTCGCCTCTTTAACGCCGATGATGTCTTGTTCTCTTTCAATCGCGTCATAGATACCGACAACCCTT
ATCATCGAGTTTCAAAAACAGGTTACCCCTTCTTCCAGAGTATCGGCTTTAATCAAACGATTAATCAGATTGAAAGAGTC
GCCGATGATGAGGTGGTATTTCATTTAAATCAAAGCGACGCTTCGTTCCTTTCCAACCTAGCAACGGGTTTTTCAGTCAT
TCTTTCTAAAGAATATGCCGATAACCTCTTGGCTCAGGGCACACCGGAACTACTGGATAGAAAGCCCGTGGGTACCGGCC
CTTTTAAGCTAGTAAAGTATGTGAAAAACGAACTGATCCGCTACCATCGCAATGATAACTTTTGGCGCACACTACCGGAA
TTTGAACAGCTAGTGTTTAACATCACGCCACAAAGTAGTACCAGATTAACTAAGTTGATCACCGGTGATTGTAGCGTATC
GGCATTGCCGAAGGCGGGCGAGTTGCCCGTCATTAAAGAGCATCCTAATCTTGAACTCGACACTCAACTCGGCTTCAATG
TCGCTTTTTGGGCGTTCAATACCAAGAAAAAACCTTTCGATGATGTACGGGTACGCCAAGCGTTAGCCTACGCCGTCGAT
AAGCAGAATATCTTACGCGCGGTATACCAAGAAACGGCCATTAAGGCGACAGGCATGCTGCCGCCGCAATCTTGGGCTTA
TCACTACAATAAAAGTACTTATCAATATAACCCTGAAAAAGCACGGGCGTTATTAGATGATGCTGGCATCGAAAATTTAA
CTATCGATATCTGGGCAATGCCCGTCGCTCGAATTTACAATCCTAATGCATTAAAAACCGCCGAGTTAATTCAGGCCGAT
TTGGCCAACATTGGGGTGAAAGTGAATATCGTGACCTACGATTGGAGTGTGTTTAACCAAAAGCTCAGTCTTAACGATTA
TGACTCGGTACTGATTGGTTGGAATGCAGACAATAGCGACCCCGATAATTTCTTCTCGCCTATGATGAGTTGTGATGCAC
TTAAATCATCGAGTAACCGCGCTCAGTGGTGCAATCTTGAGTTGGATCGGATTCTAGCCAAGGCAAAAGCCACAACATCA
GAATCAGAACGTAAAGTACTCTATCAGCAAGCTGAAGCCTTATTTACAGAGCATGTGCCGATGATGACATTTGCCCATGC
CACGCAACTGACCTTTAAGAGCAAAGATATTAAACAAACTCAGCTTACTCCTTTTGGTGGGATCTCATTTGAACGAGCCA
AGAAAATAACATCAGAGGAGGAGCTATAA

Upstream 100 bases:

>100_bases
GGGATCTTAAAGAAATACAACTTGCTGGATAAATAATTGCTGTTAGCTAGCAGGCACTGTTAAAATAGCTAATAATGTTC
AGTTCAAAAATGACTGCTTA

Downstream 100 bases:

>100_bases
TGGGCCGCTATCTCCTACGCAGATTAAACCTGTTTATAGCAACCAGTTTTGTCCTAATTGCTGTCTTGTTCATAACAACG
GGTTATTTTCCAACCAATAA

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MKQLLKRIKLIAGISLINLLLTACGPQQVPTGLVYCSEGNPETFNPQLVTSGTTIDATSQQLYDSLVDYDPVSGEIVPAL
ATSWETSADGLSYRFKLRHGVQFHQTSLFSPTRLFNADDVLFSFNRVIDTDNPYHRVSKTGYPFFQSIGFNQTINQIERV
ADDEVVFHLNQSDASFLSNLATGFSVILSKEYADNLLAQGTPELLDRKPVGTGPFKLVKYVKNELIRYHRNDNFWRTLPE
FEQLVFNITPQSSTRLTKLITGDCSVSALPKAGELPVIKEHPNLELDTQLGFNVAFWAFNTKKKPFDDVRVRQALAYAVD
KQNILRAVYQETAIKATGMLPPQSWAYHYNKSTYQYNPEKARALLDDAGIENLTIDIWAMPVARIYNPNALKTAELIQAD
LANIGVKVNIVTYDWSVFNQKLSLNDYDSVLIGWNADNSDPDNFFSPMMSCDALKSSSNRAQWCNLELDRILAKAKATTS
ESERKVLYQQAEALFTEHVPMMTFAHATQLTFKSKDIKQTQLTPFGGISFERAKKITSEEEL

Sequences:

>Translated_542_residues
MKQLLKRIKLIAGISLINLLLTACGPQQVPTGLVYCSEGNPETFNPQLVTSGTTIDATSQQLYDSLVDYDPVSGEIVPAL
ATSWETSADGLSYRFKLRHGVQFHQTSLFSPTRLFNADDVLFSFNRVIDTDNPYHRVSKTGYPFFQSIGFNQTINQIERV
ADDEVVFHLNQSDASFLSNLATGFSVILSKEYADNLLAQGTPELLDRKPVGTGPFKLVKYVKNELIRYHRNDNFWRTLPE
FEQLVFNITPQSSTRLTKLITGDCSVSALPKAGELPVIKEHPNLELDTQLGFNVAFWAFNTKKKPFDDVRVRQALAYAVD
KQNILRAVYQETAIKATGMLPPQSWAYHYNKSTYQYNPEKARALLDDAGIENLTIDIWAMPVARIYNPNALKTAELIQAD
LANIGVKVNIVTYDWSVFNQKLSLNDYDSVLIGWNADNSDPDNFFSPMMSCDALKSSSNRAQWCNLELDRILAKAKATTS
ESERKVLYQQAEALFTEHVPMMTFAHATQLTFKSKDIKQTQLTPFGGISFERAKKITSEEEL
>Mature_542_residues
MKQLLKRIKLIAGISLINLLLTACGPQQVPTGLVYCSEGNPETFNPQLVTSGTTIDATSQQLYDSLVDYDPVSGEIVPAL
ATSWETSADGLSYRFKLRHGVQFHQTSLFSPTRLFNADDVLFSFNRVIDTDNPYHRVSKTGYPFFQSIGFNQTINQIERV
ADDEVVFHLNQSDASFLSNLATGFSVILSKEYADNLLAQGTPELLDRKPVGTGPFKLVKYVKNELIRYHRNDNFWRTLPE
FEQLVFNITPQSSTRLTKLITGDCSVSALPKAGELPVIKEHPNLELDTQLGFNVAFWAFNTKKKPFDDVRVRQALAYAVD
KQNILRAVYQETAIKATGMLPPQSWAYHYNKSTYQYNPEKARALLDDAGIENLTIDIWAMPVARIYNPNALKTAELIQAD
LANIGVKVNIVTYDWSVFNQKLSLNDYDSVLIGWNADNSDPDNFFSPMMSCDALKSSSNRAQWCNLELDRILAKAKATTS
ESERKVLYQQAEALFTEHVPMMTFAHATQLTFKSKDIKQTQLTPFGGISFERAKKITSEEEL

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=533, Percent_Identity=43.9024390243902, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI1787551, Length=533, Percent_Identity=39.9624765478424, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1787052, Length=541, Percent_Identity=24.0295748613678, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789887, Length=558, Percent_Identity=23.6559139784946, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787762, Length=471, Percent_Identity=23.7791932059448, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789397, Length=509, Percent_Identity=26.5225933202358, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787495, Length=521, Percent_Identity=23.6084452975048, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87081878, Length=522, Percent_Identity=22.7969348659004, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61025; Mature: 61025

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLLKRIKLIAGISLINLLLTACGPQQVPTGLVYCSEGNPETFNPQLVTSGTTIDATSQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEECCCEECCHHH
QLYDSLVDYDPVSGEIVPALATSWETSADGLSYRFKLRHGVQFHQTSLFSPTRLFNADDV
HHHHHHHCCCCCCCCEEHHHHCCCCCCCCCCEEEEEECCCCEEHHHCCCCCHHHCCCCHH
LFSFNRVIDTDNPYHRVSKTGYPFFQSIGFNQTINQIERVADDEVVFHLNQSDASFLSNL
HHHHHHHCCCCCCHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
ATGFSVILSKEYADNLLAQGTPELLDRKPVGTGPFKLVKYVKNELIRYHRNDNFWRTLPE
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHH
FEQLVFNITPQSSTRLTKLITGDCSVSALPKAGELPVIKEHPNLELDTQLGFNVAFWAFN
HHHHHEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCEEECCCCCEEEEEEEC
TKKKPFDDVRVRQALAYAVDKQNILRAVYQETAIKATGMLPPQSWAYHYNKSTYQYNPEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEECHHH
ARALLDDAGIENLTIDIWAMPVARIYNPNALKTAELIQADLANIGVKVNIVTYDWSVFNQ
HHHHHHHCCCCEEEEEEEECCHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEEEEHHHHCC
KLSLNDYDSVLIGWNADNSDPDNFFSPMMSCDALKSSSNRAQWCNLELDRILAKAKATTS
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCC
ESERKVLYQQAEALFTEHVPMMTFAHATQLTFKSKDIKQTQLTPFGGISFERAKKITSEE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCHHCCCCCCCCCHHHHHHCCCCC
EL
CC
>Mature Secondary Structure
MKQLLKRIKLIAGISLINLLLTACGPQQVPTGLVYCSEGNPETFNPQLVTSGTTIDATSQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEECCCEECCHHH
QLYDSLVDYDPVSGEIVPALATSWETSADGLSYRFKLRHGVQFHQTSLFSPTRLFNADDV
HHHHHHHCCCCCCCCEEHHHHCCCCCCCCCCEEEEEECCCCEEHHHCCCCCHHHCCCCHH
LFSFNRVIDTDNPYHRVSKTGYPFFQSIGFNQTINQIERVADDEVVFHLNQSDASFLSNL
HHHHHHHCCCCCCHHHHCCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
ATGFSVILSKEYADNLLAQGTPELLDRKPVGTGPFKLVKYVKNELIRYHRNDNFWRTLPE
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHH
FEQLVFNITPQSSTRLTKLITGDCSVSALPKAGELPVIKEHPNLELDTQLGFNVAFWAFN
HHHHHEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCEEECCCCCEEEEEEEC
TKKKPFDDVRVRQALAYAVDKQNILRAVYQETAIKATGMLPPQSWAYHYNKSTYQYNPEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEECHHH
ARALLDDAGIENLTIDIWAMPVARIYNPNALKTAELIQADLANIGVKVNIVTYDWSVFNQ
HHHHHHHCCCCEEEEEEEECCHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEEEEHHHHCC
KLSLNDYDSVLIGWNADNSDPDNFFSPMMSCDALKSSSNRAQWCNLELDRILAKAKATTS
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCC
ESERKVLYQQAEALFTEHVPMMTFAHATQLTFKSKDIKQTQLTPFGGISFERAKKITSEE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCHHCCCCCCCCCHHHHHHCCCCC
EL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]