Click here to switch to the map view.

The map label for this gene is speB [H]

Identifier: 157962299

GI number: 157962299

Start: 3022869

End: 3023798

Strand: Reverse

Name: speB [H]

Synonym: Spea_2478

Alternate gene names: 157962299

Gene position: 3023798-3022869 (Counterclockwise)

Preceding gene: 157962300

Following gene: 157962298

Centisome position: 58.44

GC content: 45.81

Gene sequence:

>930_bases
ATGACCACTATTGCAGATAAGCCTGATTATTCGCTTTATTCAAATGCATTTGGTTACTTAAGACAGCCGCTAGACTTCAA
ACCATTAGAAGGCGATGCGGATGTTGTAGTGTTAGGCTTACCTTTTGATATGGCTACTACGGGTCGCTCTGGTGGACGTA
TGGGCCCAGGTGCAATTCGTAATGCTTCAGTAAACCTGGCTTGGGAAGAAACTCGCTGGCCTTATCAGTTTAAACTAAGC
GAGCATGTTAAAATCGTCGATGCAGGCGATCTCGTTTATAACTGTGGTGATTCTGCAGACTTCACACAGCGTGTTGAAGA
TTTCGCAACTAAGATCTTAGAAGCTGATAAGGCTATGCTAAGTTTTGGTGGCGATCACTTTGTGACTTTGCCCCTGCTAC
GTGCTCACTATAAGAAGCACGGTAAGATGGCGCTATTGCACTTTGATGCACATACCGACACTTATAGCCAAGGTAGTAAG
TATGATCACGGCACCATGTTTTATCATGCGCCAAACGAAGGGATCATTGCTGCAGAGAACTCAATTCAAGTCGGTATCCG
TACTGAATACGATACTTCCAATCATCTTTTCAAAGTTATCGATGCGGCGGCAGCTAATGAAATGACTGCTGATGAGATCG
TTGCACAAATTCGTGAACGTGTTGGCGATATGCCGCTATACGTGACTTTCGATATTGACTGTTTAGACCCAGCTTTCGCT
CCTGGCACAGGTACGCCAGTATGTGGCGGTTTGACCAGTGACAAGGCGATGAAAATCATTCGTGGTTTAAAAGGCATGAA
GATTGTGGGTATGGACGTGGTTGAAGTGGCACCAGCCTACGACAGCGCAGAGATCACTGCTTTAGCGGGTGCTACTTTGG
GCCTAGAGATGTTGCACGTTTGGGCTGAGTCTAACGGCAAGATCAAATAA

Upstream 100 bases:

>100_bases
AAATCAACTTAATGAATTTAATTACAATCACTATATTCAAGCGGACAGTGAAATCCTGTGTGCAGAAGTATTGTGACTCT
AGACACTTTATGGAGTATTT

Downstream 100 bases:

>100_bases
GTCATCATAGCTAGCATGTTAGATGAAAATATCTAGTTAGGGAGTGTATTAAAAGGCTCCCGTCTAACGGCTAAGATTGT
TATGATTAAAGAAGCGCTCA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTTIADKPDYSLYSNAFGYLRQPLDFKPLEGDADVVVLGLPFDMATTGRSGGRMGPGAIRNASVNLAWEETRWPYQFKLS
EHVKIVDAGDLVYNCGDSADFTQRVEDFATKILEADKAMLSFGGDHFVTLPLLRAHYKKHGKMALLHFDAHTDTYSQGSK
YDHGTMFYHAPNEGIIAAENSIQVGIRTEYDTSNHLFKVIDAAAANEMTADEIVAQIRERVGDMPLYVTFDIDCLDPAFA
PGTGTPVCGGLTSDKAMKIIRGLKGMKIVGMDVVEVAPAYDSAEITALAGATLGLEMLHVWAESNGKIK

Sequences:

>Translated_309_residues
MTTIADKPDYSLYSNAFGYLRQPLDFKPLEGDADVVVLGLPFDMATTGRSGGRMGPGAIRNASVNLAWEETRWPYQFKLS
EHVKIVDAGDLVYNCGDSADFTQRVEDFATKILEADKAMLSFGGDHFVTLPLLRAHYKKHGKMALLHFDAHTDTYSQGSK
YDHGTMFYHAPNEGIIAAENSIQVGIRTEYDTSNHLFKVIDAAAANEMTADEIVAQIRERVGDMPLYVTFDIDCLDPAFA
PGTGTPVCGGLTSDKAMKIIRGLKGMKIVGMDVVEVAPAYDSAEITALAGATLGLEMLHVWAESNGKIK
>Mature_308_residues
TTIADKPDYSLYSNAFGYLRQPLDFKPLEGDADVVVLGLPFDMATTGRSGGRMGPGAIRNASVNLAWEETRWPYQFKLSE
HVKIVDAGDLVYNCGDSADFTQRVEDFATKILEADKAMLSFGGDHFVTLPLLRAHYKKHGKMALLHFDAHTDTYSQGSKY
DHGTMFYHAPNEGIIAAENSIQVGIRTEYDTSNHLFKVIDAAAANEMTADEIVAQIRERVGDMPLYVTFDIDCLDPAFAP
GTGTPVCGGLTSDKAMKIIRGLKGMKIVGMDVVEVAPAYDSAEITALAGATLGLEMLHVWAESNGKIK

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=291, Percent_Identity=38.4879725085911, Blast_Score=194, Evalue=6e-50,
Organism=Homo sapiens, GI4502215, Length=305, Percent_Identity=24.2622950819672, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI10947139, Length=283, Percent_Identity=24.0282685512367, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789306, Length=307, Percent_Identity=61.5635179153095, Blast_Score=392, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6325146, Length=206, Percent_Identity=27.1844660194175, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33708; Mature: 33576

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIADKPDYSLYSNAFGYLRQPLDFKPLEGDADVVVLGLPFDMATTGRSGGRMGPGAIR
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
NASVNLAWEETRWPYQFKLSEHVKIVDAGDLVYNCGDSADFTQRVEDFATKILEADKAML
CCEEEEEECCCCCCEEEEECCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SFGGDHFVTLPLLRAHYKKHGKMALLHFDAHTDTYSQGSKYDHGTMFYHAPNEGIIAAEN
HCCCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEECC
SIQVGIRTEYDTSNHLFKVIDAAAANEMTADEIVAQIRERVGDMPLYVTFDIDCLDPAFA
CEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
PGTGTPVCGGLTSDKAMKIIRGLKGMKIVGMDVVEVAPAYDSAEITALAGATLGLEMLHV
CCCCCCCCCCCCCHHHHHHHHCCCCCEEECCHHEEECCCCCCCEEEEECCCHHHHHHHEE
WAESNGKIK
EECCCCCCC
>Mature Secondary Structure 
TTIADKPDYSLYSNAFGYLRQPLDFKPLEGDADVVVLGLPFDMATTGRSGGRMGPGAIR
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
NASVNLAWEETRWPYQFKLSEHVKIVDAGDLVYNCGDSADFTQRVEDFATKILEADKAML
CCEEEEEECCCCCCEEEEECCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
SFGGDHFVTLPLLRAHYKKHGKMALLHFDAHTDTYSQGSKYDHGTMFYHAPNEGIIAAEN
HCCCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEECC
SIQVGIRTEYDTSNHLFKVIDAAAANEMTADEIVAQIRERVGDMPLYVTFDIDCLDPAFA
CEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
PGTGTPVCGGLTSDKAMKIIRGLKGMKIVGMDVVEVAPAYDSAEITALAGATLGLEMLHV
CCCCCCCCCCCCCHHHHHHHHCCCCCEEECCHHEEECCCCCCCEEEEECCCHHHHHHHEE
WAESNGKIK
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA