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The map label for this gene is hlyB [H]

Identifier: 157962219

GI number: 157962219

Start: 2923555

End: 2925525

Strand: Direct

Name: hlyB [H]

Synonym: Spea_2398

Alternate gene names: 157962219

Gene position: 2923555-2925525 (Clockwise)

Preceding gene: 157962214

Following gene: 157962224

Centisome position: 56.5

GC content: 38.91

Gene sequence:

>1971_bases
ATGACGGTAAATTACATGGATTTAAGTGATATTTCGATAAGAGCAAGATTACTTGCTAGTAATATTATTATTTGTAGCAT
CCTGATTGTATTCAATATTGTTGTATACAAATCAATATCAACCATGGAAACAACTTCACACTGGGTAGACCACACTGAAG
AGGTAATAGCTCTAACCAATGGTCTCGTCAACTCAATGGTTAATCAAGAAACAGGAATTAGAGGGTATGCCATAACTGGA
GAAAATGAATACCTAGAGCCCTATTTATCAGGCAAGGAAGACTTTCAAACATTTTTTAATGCTGCAAAATTGTTAACCTC
AGACAACCCTTCTCAGCAAGTACGCTATGATGACGTTGCAAAGCAATCAAAGCTATGGGGTGAGTATGCCGAATCCATTA
TTTCGCTGCGTAAAAATATCCGAAGTGGTGAACAAATTAATACACAGCTTAAGGAATTAATTAATTCAGGTATCGGCAAG
CAACAAATGGATAACATAAGGCTTGAGTTAAATAAGCTTGGATCTTCAAATTTAAATATCACAGTACTAAATGCCATGGT
TAATATGGAGACAGGTTTACGCGGCTTTTTACTCAACCGTCAAGAAACTTATCTTGAACCATATCAAACTGGAAAAAACG
TGATAGACCAACAAAACTCCAATATCAAGGAAACTAGACTCGCAGAGTCTATTGATTCATGGATTAATGACTACGCCCAA
CAAGCGATTACATTAACTCGTCAATCAACTCAGTTCAAATCAATGTCAGATCTCTATGCTGTGCTAGACAAGAAGCAGGG
GAAAGTATACATGGATGAATTGCGTTCGAAAGTAACTGGCATCATTGATGTTGAGCTTAGTTTGATGGAACAAAGAAAAG
CCGAATCAGCAAGTGCGGCAACTATGGCAACAAGGGTCATCATATGGGGTTGCATTATAGTCATTCTACTTGTCTTTGTA
TTTTCTCATATCACATCAGTAAGTATCATTAACCCCATCCAACAAGCCGTAGCCTATGCAAAACAATTAGCCGCAGGTAA
TTTAAATATTAATGTTGGACAACAAGGTAAGAGTGAATCAGGCGTACTGCTATTAGCAATCCAAACTGTTTCAAATAATC
TGAAGGACATGATCGGACACATTGCACAAACCAGTAGTAAACTCAATGACGCTTCAACGTACCTAAACTCAGTGCTTGAT
AAGACAGGCTCTGGCGCAAAAGATCAGCTAGATAAAACTGAGCAAATAACAGATGCCATGCAACAGTTATCGCTTGCCGT
ACAGGAGGTCTCGCAAAATACCGTAAATGCTTCGCATGTCGCGACGAAAGCTGTTGATGAAGCCGAGGCTGGCTATGGAG
TTATCCAAAATACCATCGGACATATTGGTGATTTAAATGATGAGATTAAACGAACGTCCTTAAAAATTACTAGTCTTGCA
GAAGAGACAAACAATATCGGTAAGATTCTCGACGTAATTGGTGGCGTTGCTGAGCAAACTAATTTATTGGCACTAAACGC
TGCGATAGAAGCTGCTCGGGCGGGTGAACAAGGGCGAGGATTTGCAGTTGTCGCTGACGAAGTGCGTGTGCTAGCTCAAA
GAACACAAGAATCGACTACTGAAATACATTCTTTAATTGAAAGTATTCAAAGTGGTACAAAAGATGTTGTTAATAGTATG
CAGCAAAGTACTGGCTTATTAACAGCAAGCATCGACTCAGCAAGTCATTCAGGTGGGACATTTTCAGAAATTACGCGATC
CATCACCAAAATTAATGACATGAATACGCAAAGCGCTAGCGCAACAGAGCAGCAAAGCGTTGCAACTGAACAAGTTAATA
CTAGTATGTTGGCAGTCAATAGCATCTCTCAAGAAAATTACACTTTAATGATGGACTCAGTTAGGTCGTGTGAAGACCTA
ACAAACCTGTCAAATTCATTAAATGCTACTGTTAAGCAATTCAAGATGTAA

Upstream 100 bases:

>100_bases
TAATTAATGATAACGGCCCCTACTGAAGTAGGTGGTTTAGGGCTGAAAACAAAATGAGCACACACCTCACGCGTACCCTA
CACTTAATTTATTACGGACA

Downstream 100 bases:

>100_bases
CCAGAAATACTGACTTAATTAAAGTATGTAAATTAAGTCAGTATTCATCGCTAGCTAGGGTTAACCATGGCTATAGCCAA
ATTGAACTCGGTTAAAATTA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 655

Protein sequence:

>656_residues
MTVNYMDLSDISIRARLLASNIIICSILIVFNIVVYKSISTMETTSHWVDHTEEVIALTNGLVNSMVNQETGIRGYAITG
ENEYLEPYLSGKEDFQTFFNAAKLLTSDNPSQQVRYDDVAKQSKLWGEYAESIISLRKNIRSGEQINTQLKELINSGIGK
QQMDNIRLELNKLGSSNLNITVLNAMVNMETGLRGFLLNRQETYLEPYQTGKNVIDQQNSNIKETRLAESIDSWINDYAQ
QAITLTRQSTQFKSMSDLYAVLDKKQGKVYMDELRSKVTGIIDVELSLMEQRKAESASAATMATRVIIWGCIIVILLVFV
FSHITSVSIINPIQQAVAYAKQLAAGNLNINVGQQGKSESGVLLLAIQTVSNNLKDMIGHIAQTSSKLNDASTYLNSVLD
KTGSGAKDQLDKTEQITDAMQQLSLAVQEVSQNTVNASHVATKAVDEAEAGYGVIQNTIGHIGDLNDEIKRTSLKITSLA
EETNNIGKILDVIGGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLAQRTQESTTEIHSLIESIQSGTKDVVNSM
QQSTGLLTASIDSASHSGGTFSEITRSITKINDMNTQSASATEQQSVATEQVNTSMLAVNSISQENYTLMMDSVRSCEDL
TNLSNSLNATVKQFKM

Sequences:

>Translated_656_residues
MTVNYMDLSDISIRARLLASNIIICSILIVFNIVVYKSISTMETTSHWVDHTEEVIALTNGLVNSMVNQETGIRGYAITG
ENEYLEPYLSGKEDFQTFFNAAKLLTSDNPSQQVRYDDVAKQSKLWGEYAESIISLRKNIRSGEQINTQLKELINSGIGK
QQMDNIRLELNKLGSSNLNITVLNAMVNMETGLRGFLLNRQETYLEPYQTGKNVIDQQNSNIKETRLAESIDSWINDYAQ
QAITLTRQSTQFKSMSDLYAVLDKKQGKVYMDELRSKVTGIIDVELSLMEQRKAESASAATMATRVIIWGCIIVILLVFV
FSHITSVSIINPIQQAVAYAKQLAAGNLNINVGQQGKSESGVLLLAIQTVSNNLKDMIGHIAQTSSKLNDASTYLNSVLD
KTGSGAKDQLDKTEQITDAMQQLSLAVQEVSQNTVNASHVATKAVDEAEAGYGVIQNTIGHIGDLNDEIKRTSLKITSLA
EETNNIGKILDVIGGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLAQRTQESTTEIHSLIESIQSGTKDVVNSM
QQSTGLLTASIDSASHSGGTFSEITRSITKINDMNTQSASATEQQSVATEQVNTSMLAVNSISQENYTLMMDSVRSCEDL
TNLSNSLNATVKQFKM
>Mature_655_residues
TVNYMDLSDISIRARLLASNIIICSILIVFNIVVYKSISTMETTSHWVDHTEEVIALTNGLVNSMVNQETGIRGYAITGE
NEYLEPYLSGKEDFQTFFNAAKLLTSDNPSQQVRYDDVAKQSKLWGEYAESIISLRKNIRSGEQINTQLKELINSGIGKQ
QMDNIRLELNKLGSSNLNITVLNAMVNMETGLRGFLLNRQETYLEPYQTGKNVIDQQNSNIKETRLAESIDSWINDYAQQ
AITLTRQSTQFKSMSDLYAVLDKKQGKVYMDELRSKVTGIIDVELSLMEQRKAESASAATMATRVIIWGCIIVILLVFVF
SHITSVSIINPIQQAVAYAKQLAAGNLNINVGQQGKSESGVLLLAIQTVSNNLKDMIGHIAQTSSKLNDASTYLNSVLDK
TGSGAKDQLDKTEQITDAMQQLSLAVQEVSQNTVNASHVATKAVDEAEAGYGVIQNTIGHIGDLNDEIKRTSLKITSLAE
ETNNIGKILDVIGGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLAQRTQESTTEIHSLIESIQSGTKDVVNSMQ
QSTGLLTASIDSASHSGGTFSEITRSITKINDMNTQSASATEQQSVATEQVNTSMLAVNSISQENYTLMMDSVRSCEDLT
NLSNSLNATVKQFKM

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=352, Percent_Identity=30.1136363636364, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI2367378, Length=328, Percent_Identity=32.0121951219512, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1788195, Length=328, Percent_Identity=30.4878048780488, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1787690, Length=443, Percent_Identity=25.5079006772009, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1789453, Length=355, Percent_Identity=27.3239436619718, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 71749; Mature: 71618

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVNYMDLSDISIRARLLASNIIICSILIVFNIVVYKSISTMETTSHWVDHTEEVIALTN
CEECEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVNSMVNQETGIRGYAITGENEYLEPYLSGKEDFQTFFNAAKLLTSDNPSQQVRYDDVA
HHHHHHHHHCCCCCEEEECCCCCHHCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
KQSKLWGEYAESIISLRKNIRSGEQINTQLKELINSGIGKQQMDNIRLELNKLGSSNLNI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCE
TVLNAMVNMETGLRGFLLNRQETYLEPYQTGKNVIDQQNSNIKETRLAESIDSWINDYAQ
EEEEHHHHHHCCCHHHHCCCHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QAITLTRQSTQFKSMSDLYAVLDKKQGKVYMDELRSKVTGIIDVELSLMEQRKAESASAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHH
TMATRVIIWGCIIVILLVFVFSHITSVSIINPIQQAVAYAKQLAAGNLNINVGQQGKSES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
GVLLLAIQTVSNNLKDMIGHIAQTSSKLNDASTYLNSVLDKTGSGAKDQLDKTEQITDAM
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QQLSLAVQEVSQNTVNASHVATKAVDEAEAGYGVIQNTIGHIGDLNDEIKRTSLKITSLA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EETNNIGKILDVIGGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLAQRTQESTT
HHHHHHHHHHHHHCCHHHCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
EIHSLIESIQSGTKDVVNSMQQSTGLLTASIDSASHSGGTFSEITRSITKINDMNTQSAS
HHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
ATEQQSVATEQVNTSMLAVNSISQENYTLMMDSVRSCEDLTNLSNSLNATVKQFKM
CHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVNYMDLSDISIRARLLASNIIICSILIVFNIVVYKSISTMETTSHWVDHTEEVIALTN
EECEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVNSMVNQETGIRGYAITGENEYLEPYLSGKEDFQTFFNAAKLLTSDNPSQQVRYDDVA
HHHHHHHHHCCCCCEEEECCCCCHHCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
KQSKLWGEYAESIISLRKNIRSGEQINTQLKELINSGIGKQQMDNIRLELNKLGSSNLNI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCE
TVLNAMVNMETGLRGFLLNRQETYLEPYQTGKNVIDQQNSNIKETRLAESIDSWINDYAQ
EEEEHHHHHHCCCHHHHCCCHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
QAITLTRQSTQFKSMSDLYAVLDKKQGKVYMDELRSKVTGIIDVELSLMEQRKAESASAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHH
TMATRVIIWGCIIVILLVFVFSHITSVSIINPIQQAVAYAKQLAAGNLNINVGQQGKSES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
GVLLLAIQTVSNNLKDMIGHIAQTSSKLNDASTYLNSVLDKTGSGAKDQLDKTEQITDAM
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
QQLSLAVQEVSQNTVNASHVATKAVDEAEAGYGVIQNTIGHIGDLNDEIKRTSLKITSLA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
EETNNIGKILDVIGGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLAQRTQESTT
HHHHHHHHHHHHHCCHHHCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
EIHSLIESIQSGTKDVVNSMQQSTGLLTASIDSASHSGGTFSEITRSITKINDMNTQSAS
HHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
ATEQQSVATEQVNTSMLAVNSISQENYTLMMDSVRSCEDLTNLSNSLNATVKQFKM
CHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]