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The map label for this gene is fadE [H]

Identifier: 157962214

GI number: 157962214

Start: 2915939

End: 2918386

Strand: Direct

Name: fadE [H]

Synonym: Spea_2393

Alternate gene names: 157962214

Gene position: 2915939-2918386 (Clockwise)

Preceding gene: 157962212

Following gene: 157962219

Centisome position: 56.35

GC content: 47.39

Gene sequence:

>2448_bases
GTGACTACCCTACTTTGGATCATGGCGTTGATTTTTACCATAGGCGCTTTAGCTTATCTAAGAGTCTCTCTTTTAACCGC
CACCTTAGGCACCGCGGTTGTATTAGCAATCGGAACCGGCGCCGCGAGCTTAAGCCCATTACTCTGGGTAGTATTTCTTG
CCATTGCCCTGCCTCTTAATATCAGCTCATTCAGACAGAACGTCATCACTCGACCCCTTCTTAAGATGTACCGTGGCATT
ATGCCGGAGATGTCTTCAACAGAAAAAGAAGCCATCGAAGCGGGAACCACATGGTGGGAAGCAGACCTATTTGCAGGTAA
GCCCGATTGGAGCAAACTTCATAACTATCCAAAAGCTAGCCTAAGTGCCGAAGAGCAAGCTTTCCTCGACGGTCCTGTTG
AAGAAGTTTGTCGCATGCTAAACCAACATCAAGTTTCTCATGAGTTAGGTGATTTACCAGAAGAAATCTGGCAATACCTT
AAAGATCATGGCTTCTTTGCGATGATCATTAAAAAGAAATATGGCGGCTTAGAGTATTCAGCTTATGCACAATCACGTGT
ATTGCAAAAACTTGCAGGTCTAAGCAGCGAGCTTGCCTCAACGGTTGGTGTTCCTAACTCATTAGGCCCTGGTGAACTAC
TGCAGCATTATGGCACCAAAGCTCAGCAAGACCATTACCTGCCCCGTCTTGCTCAAGGTCTAGAAGTCCCTTGCTTTGCA
TTAACTAGCCCAGAAGCTGGCAGCGATGCAGGCGCTATTCCTGATTTCGGTATCGTGTGTAAAGGCGAATGGGAAGGCGA
AGAAGTACTGGGTATGAAACTAACCTGGAACAAGCGTTATATTACCCTTGCGCCAGTAGCTACAGTACTTGGCCTTGCAT
TTAAGCTTCGCGATCCAGACCAATTACTTGGCAATCAAGAAGATTTAGGCATTACCTGTGCACTTATTCCTACCGACATT
GAAGGTGTTGAAACTGGCCGCCGCCACTTCCCACTAAACTGTATGTTCCAAAATGGTCCTACTCGCGGTAATGAAGTGTT
TGTACCACTGAGCTTCATTATTGGTGGCGTTGAAATGGCTGGCCAAGGCTGGAGAATGCTGGTTGAGTGCCTATCGGTTG
GACGTGGTATTACTTTGCCGTCAAACTCTGCCGGTGGTATTAAAACTGCAGCCGTTGCAACGGGGGCTTACGCCCGCATT
CGCCGCCAGTTCAAGCTACCTATCGGTAAACTTGAAGGCATCGAAGAGCCGATGGCTCGCATTGGTGGTAACGCTTATCT
TATGGATGCGGTAACCACACTGACTACAACGGGTATCGACCTTGGTGAAAAGCCATCGGTTATCTCAGCGATTGTGAAAT
TTCATCTCACTGACAGAATGCAACGATGTGTCATTGACGCCATGGACATTCACGGTGGTAAAGGGGTGTGTTTAGGCCCA
AATAACTATCTTGGTCGTGGTTATCAGGCAGCGCCTATTGCAATTACGGTTGAGGGGGCAAACATTCTCACTCGCTCGAT
GATTATCTATGGTCAAGGTGCTATTCGCTGCCATCCGTATGTATTAGCCGAAATGGAATCGGCGTTCGATCCAGATGCAA
ACAAGGGCCTACGTGATTTTGATGCGGCTATCTTTGGGCATATCGGATTTACCACCAGCAACCTAGTACGTAGCTTGTGG
ATGGGTCTAACGTCTAGCCGTTTCTCTAATGCGCCATACTCGGATAAGACGAAGCGTTACTATCAGCAGATGAACCGGTT
CAGTGCAAACTTGGCGTTACTATCAGATCTAGCAATGGCAACATTAGGTGGTAACCTTAAGCGCAAAGAACGGATCTCAG
CACGTCTTGGCGACTTACTCAGCCAGCTTTATTTAGCATCGGCAACCCTTAAGCGCTACGAAGATGAAGGCCGACTCACC
GAAGATCTACCATTAGTACAGTGGGCAGTTGAAGACTCACTCTACAAATTACAATCATCTTTAGATGATCTACTCGACAA
CTTCCCCATGGGTTTAGGTATTGGACTACGCGCAGTGATCTTCCCATTCGGTCGTCCACTTAAGCGCCCAAGTGATGTGC
TTGACCATAAGGTCGCTAAGATCATGCAAACCCCTTGTGCAAGCCGCGACCGCCTTGGTAAAGGCCAGTTCTGGACGCCA
ACAGAGCATAATGCTGTGGGTATTCAAGAGCAGACCTTTAAGGATATCTTGGCATCAGAACCTATCTACGACAAAGTCTG
TAAGGCCGCAGGTAAACGCCTACCCTTTATGTGGTTAGATAAAATAGCTGCAGAAGGTAAAGAGCTTGGTGTGCTAAGTG
AAGAAGAAGTCGCATTACTTGAACGAGCCGAAATTGGCCGTATGAAGTCAATCAACGTCGATGACTTTGATCCTGAAGAG
CTAAAAGCTCGCACGCTTGAGTACACAAAAGAGGTGCAAGCAGCTTAA

Upstream 100 bases:

>100_bases
TTATGAAACACAGGTCTGACCACAGGCTATAATTGTGAGATAGAACTCAAAATAAGTGTCTTTAGGTTAACTATAGCTCA
CACATAAAAGGAGAATTACA

Downstream 100 bases:

>100_bases
TTACTGAGCAGAAGCACGCAGTAAAAGGCTTAAGTATTCACTTAAGCCTTTTTTATTTTTCATTCGTAATCAGCTTTCAA
CTAATCCAGTACTAAAACTA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MTTLLWIMALIFTIGALAYLRVSLLTATLGTAVVLAIGTGAASLSPLLWVVFLAIALPLNISSFRQNVITRPLLKMYRGI
MPEMSSTEKEAIEAGTTWWEADLFAGKPDWSKLHNYPKASLSAEEQAFLDGPVEEVCRMLNQHQVSHELGDLPEEIWQYL
KDHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTKAQQDHYLPRLAQGLEVPCFA
LTSPEAGSDAGAIPDFGIVCKGEWEGEEVLGMKLTWNKRYITLAPVATVLGLAFKLRDPDQLLGNQEDLGITCALIPTDI
EGVETGRRHFPLNCMFQNGPTRGNEVFVPLSFIIGGVEMAGQGWRMLVECLSVGRGITLPSNSAGGIKTAAVATGAYARI
RRQFKLPIGKLEGIEEPMARIGGNAYLMDAVTTLTTTGIDLGEKPSVISAIVKFHLTDRMQRCVIDAMDIHGGKGVCLGP
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDPDANKGLRDFDAAIFGHIGFTTSNLVRSLW
MGLTSSRFSNAPYSDKTKRYYQQMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRLT
EDLPLVQWAVEDSLYKLQSSLDDLLDNFPMGLGIGLRAVIFPFGRPLKRPSDVLDHKVAKIMQTPCASRDRLGKGQFWTP
TEHNAVGIQEQTFKDILASEPIYDKVCKAAGKRLPFMWLDKIAAEGKELGVLSEEEVALLERAEIGRMKSINVDDFDPEE
LKARTLEYTKEVQAA

Sequences:

>Translated_815_residues
MTTLLWIMALIFTIGALAYLRVSLLTATLGTAVVLAIGTGAASLSPLLWVVFLAIALPLNISSFRQNVITRPLLKMYRGI
MPEMSSTEKEAIEAGTTWWEADLFAGKPDWSKLHNYPKASLSAEEQAFLDGPVEEVCRMLNQHQVSHELGDLPEEIWQYL
KDHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTKAQQDHYLPRLAQGLEVPCFA
LTSPEAGSDAGAIPDFGIVCKGEWEGEEVLGMKLTWNKRYITLAPVATVLGLAFKLRDPDQLLGNQEDLGITCALIPTDI
EGVETGRRHFPLNCMFQNGPTRGNEVFVPLSFIIGGVEMAGQGWRMLVECLSVGRGITLPSNSAGGIKTAAVATGAYARI
RRQFKLPIGKLEGIEEPMARIGGNAYLMDAVTTLTTTGIDLGEKPSVISAIVKFHLTDRMQRCVIDAMDIHGGKGVCLGP
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDPDANKGLRDFDAAIFGHIGFTTSNLVRSLW
MGLTSSRFSNAPYSDKTKRYYQQMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRLT
EDLPLVQWAVEDSLYKLQSSLDDLLDNFPMGLGIGLRAVIFPFGRPLKRPSDVLDHKVAKIMQTPCASRDRLGKGQFWTP
TEHNAVGIQEQTFKDILASEPIYDKVCKAAGKRLPFMWLDKIAAEGKELGVLSEEEVALLERAEIGRMKSINVDDFDPEE
LKARTLEYTKEVQAA
>Mature_814_residues
TTLLWIMALIFTIGALAYLRVSLLTATLGTAVVLAIGTGAASLSPLLWVVFLAIALPLNISSFRQNVITRPLLKMYRGIM
PEMSSTEKEAIEAGTTWWEADLFAGKPDWSKLHNYPKASLSAEEQAFLDGPVEEVCRMLNQHQVSHELGDLPEEIWQYLK
DHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTKAQQDHYLPRLAQGLEVPCFAL
TSPEAGSDAGAIPDFGIVCKGEWEGEEVLGMKLTWNKRYITLAPVATVLGLAFKLRDPDQLLGNQEDLGITCALIPTDIE
GVETGRRHFPLNCMFQNGPTRGNEVFVPLSFIIGGVEMAGQGWRMLVECLSVGRGITLPSNSAGGIKTAAVATGAYARIR
RQFKLPIGKLEGIEEPMARIGGNAYLMDAVTTLTTTGIDLGEKPSVISAIVKFHLTDRMQRCVIDAMDIHGGKGVCLGPN
NYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDPDANKGLRDFDAAIFGHIGFTTSNLVRSLWM
GLTSSRFSNAPYSDKTKRYYQQMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRLTE
DLPLVQWAVEDSLYKLQSSLDDLLDNFPMGLGIGLRAVIFPFGRPLKRPSDVLDHKVAKIMQTPCASRDRLGKGQFWTPT
EHNAVGIQEQTFKDILASEPIYDKVCKAAGKRLPFMWLDKIAAEGKELGVLSEEEVALLERAEIGRMKSINVDDFDPEEL
KARTLEYTKEVQAA

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=552, Percent_Identity=26.268115942029, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI4557235, Length=410, Percent_Identity=25.3658536585366, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI76496475, Length=389, Percent_Identity=25.706940874036, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4557233, Length=421, Percent_Identity=26.3657957244656, Blast_Score=74, Evalue=6e-13,
Organism=Escherichia coli, GI87081702, Length=819, Percent_Identity=65.4456654456654, Blast_Score=1101, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506239, Length=354, Percent_Identity=23.728813559322, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=324, Percent_Identity=22.8395061728395, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=329, Percent_Identity=24.3161094224924, Blast_Score=66, Evalue=8e-11,
Organism=Drosophila melanogaster, GI281363737, Length=449, Percent_Identity=24.7216035634744, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24646207, Length=354, Percent_Identity=24.8587570621469, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356377, Length=393, Percent_Identity=25.4452926208651, Blast_Score=70, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 89452; Mature: 89321

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLWIMALIFTIGALAYLRVSLLTATLGTAVVLAIGTGAASLSPLLWVVFLAIALPLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCC
ISSFRQNVITRPLLKMYRGIMPEMSSTEKEAIEAGTTWWEADLFAGKPDWSKLHNYPKAS
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEECCCCCCCCCHHHHHCCCCCC
LSAEEQAFLDGPVEEVCRMLNQHQVSHELGDLPEEIWQYLKDHGFFAMIIKKKYGGLEYS
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEEHHCCCCCHH
AYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTKAQQDHYLPRLAQGLEVPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEE
LTSPEAGSDAGAIPDFGIVCKGEWEGEEVLGMKLTWNKRYITLAPVATVLGLAFKLRDPD
ECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCEEEHHHHHHHHHHHHHCCCHH
QLLGNQEDLGITCALIPTDIEGVETGRRHFPLNCMFQNGPTRGNEVFVPLSFIIGGVEMA
HHHCCCCCCCEEEEEECCCCCHHCCCCCCCCEEEEECCCCCCCCEEEEEHHHHHCCHHHC
GQGWRMLVECLSVGRGITLPSNSAGGIKTAAVATGAYARIRRQFKLPIGKLEGIEEPMAR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
IGGNAYLMDAVTTLTTTGIDLGEKPSVISAIVKFHLTDRMQRCVIDAMDIHGGKGVCLGP
HCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDPDANKGLRDF
CCCCCCCCCCCCEEEEECCCHHHHHEEEEECCCCEEECHHHHHHHHHHCCCCCCCCHHHH
DAAIFGHIGFTTSNLVRSLWMGLTSSRFSNAPYSDKTKRYYQQMNRFSANLALLSDLAMA
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRLTEDLPLVQWAVEDSLYKLQSS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LDDLLDNFPMGLGIGLRAVIFPFGRPLKRPSDVLDHKVAKIMQTPCASRDRLGKGQFWTP
HHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TEHNAVGIQEQTFKDILASEPIYDKVCKAAGKRLPFMWLDKIAAEGKELGVLSEEEVALL
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCHHCCCCCHHHHHHH
ERAEIGRMKSINVDDFDPEELKARTLEYTKEVQAA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTLLWIMALIFTIGALAYLRVSLLTATLGTAVVLAIGTGAASLSPLLWVVFLAIALPLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCC
ISSFRQNVITRPLLKMYRGIMPEMSSTEKEAIEAGTTWWEADLFAGKPDWSKLHNYPKAS
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEECCCCCCCCCHHHHHCCCCCC
LSAEEQAFLDGPVEEVCRMLNQHQVSHELGDLPEEIWQYLKDHGFFAMIIKKKYGGLEYS
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEEHHCCCCCHH
AYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTKAQQDHYLPRLAQGLEVPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEE
LTSPEAGSDAGAIPDFGIVCKGEWEGEEVLGMKLTWNKRYITLAPVATVLGLAFKLRDPD
ECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCEEEHHHHHHHHHHHHHCCCHH
QLLGNQEDLGITCALIPTDIEGVETGRRHFPLNCMFQNGPTRGNEVFVPLSFIIGGVEMA
HHHCCCCCCCEEEEEECCCCCHHCCCCCCCCEEEEECCCCCCCCEEEEEHHHHHCCHHHC
GQGWRMLVECLSVGRGITLPSNSAGGIKTAAVATGAYARIRRQFKLPIGKLEGIEEPMAR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
IGGNAYLMDAVTTLTTTGIDLGEKPSVISAIVKFHLTDRMQRCVIDAMDIHGGKGVCLGP
HCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDPDANKGLRDF
CCCCCCCCCCCCEEEEECCCHHHHHEEEEECCCCEEECHHHHHHHHHHCCCCCCCCHHHH
DAAIFGHIGFTTSNLVRSLWMGLTSSRFSNAPYSDKTKRYYQQMNRFSANLALLSDLAMA
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRLTEDLPLVQWAVEDSLYKLQSS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LDDLLDNFPMGLGIGLRAVIFPFGRPLKRPSDVLDHKVAKIMQTPCASRDRLGKGQFWTP
HHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TEHNAVGIQEQTFKDILASEPIYDKVCKAAGKRLPFMWLDKIAAEGKELGVLSEEEVALL
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCHHCCCCCHHHHHHH
ERAEIGRMKSINVDDFDPEELKARTLEYTKEVQAA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]