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The map label for this gene is uspE [H]

Identifier: 157962044

GI number: 157962044

Start: 2695050

End: 2695982

Strand: Direct

Name: uspE [H]

Synonym: Spea_2223

Alternate gene names: 157962044

Gene position: 2695050-2695982 (Clockwise)

Preceding gene: 157962043

Following gene: 157962045

Centisome position: 52.08

GC content: 44.05

Gene sequence:

>933_bases
ATGATGGACTATCAGAAACTCCTTGTGGTTGTCGACCCAACGACAGAAAAACAGGCGGCTCTAGCAAGAGCCGTTGAACT
CGCCTCAGAAAGCAAAGCCGAAATTACGGTCTTTTTATCGATTTTCGACTTCTCCTACGAGATGACCTCAATTCTTTCCG
GTCAAGAAAGAGAAGCGATGCGGGAAGGTGTCATTAACCAGCGTAAAGCTTGGATAGATGACATTATAAAACCTTATTGT
AAAGATGGCATAAAAGTCACATCTGAAGTTATCTGGCATAACCGCCCTTTCGAAAGCATTATCAGACAGGCAATTGACGG
TAACTACGACCTTATCGTTAAGGGTACTCACGAGCACGATAAGCTTAAGTCGGTAATATTCACACCGACAGACTGGCATC
TTATGCGAAAAGCCCCTATCCCAGTGCTGCTAGTTAAAGAACATGACTGGCCTGTAGCGGGTAAGATAGTTTGCGCCATT
AACGTCAGTGCAGAAGACGACGCAAATGAGACGCTTAATGGTAAAATTATCACTCACGCCAGCAAACTCGCTAAGCAATT
TAATGCTCAGGTACATCTAGTTAATGGTTACCCTGGCACTCCTGTTAATTTAGCCATAGAGCTGCCTGATTTCGATGCCC
ACACTTACAGTGAAACCATTAGGCTTCAACACGAAGAACGAATTTGCTATCTAGCAAATGCCTACGGGATCTCTCCTGAC
TTTTGTCATGTAAAAGAAGGCTTACCAGAAGATGTCATCCCCGATTTAGCCGCTGAGTTAGATGCAGAGCTAGTGATTTT
AGGCACGGTAGGCAGAACCGGACTTTCTGCTGCATTAATCGGTAATACGGCAGAGCATGTCATCGACAGTATCAACTGTG
ACTTATTGGCGATAAAACCTGATGGTTATAAATCACCATTAGAAGAGGTCTAA

Upstream 100 bases:

>100_bases
GCGATAGGATTTATTCGGCAATCAGCTTGATCTAAAACAATATAAATTCATCGCAATCATGCAAGATGAAACTAGACGAT
ATTTAGATAAGGAAACGGCT

Downstream 100 bases:

>100_bases
CCGCTTTCTAAGCTTTACCCGAAGCCATTAAGCTGGAATAATACGCGCCCTGAACTATTGTGTACTAGGCGCGTTTTTTA
TGTCCGAAGAATTAACTCCA

Product: universal stress protein UspE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MMDYQKLLVVVDPTTEKQAALARAVELASESKAEITVFLSIFDFSYEMTSILSGQEREAMREGVINQRKAWIDDIIKPYC
KDGIKVTSEVIWHNRPFESIIRQAIDGNYDLIVKGTHEHDKLKSVIFTPTDWHLMRKAPIPVLLVKEHDWPVAGKIVCAI
NVSAEDDANETLNGKIITHASKLAKQFNAQVHLVNGYPGTPVNLAIELPDFDAHTYSETIRLQHEERICYLANAYGISPD
FCHVKEGLPEDVIPDLAAELDAELVILGTVGRTGLSAALIGNTAEHVIDSINCDLLAIKPDGYKSPLEEV

Sequences:

>Translated_310_residues
MMDYQKLLVVVDPTTEKQAALARAVELASESKAEITVFLSIFDFSYEMTSILSGQEREAMREGVINQRKAWIDDIIKPYC
KDGIKVTSEVIWHNRPFESIIRQAIDGNYDLIVKGTHEHDKLKSVIFTPTDWHLMRKAPIPVLLVKEHDWPVAGKIVCAI
NVSAEDDANETLNGKIITHASKLAKQFNAQVHLVNGYPGTPVNLAIELPDFDAHTYSETIRLQHEERICYLANAYGISPD
FCHVKEGLPEDVIPDLAAELDAELVILGTVGRTGLSAALIGNTAEHVIDSINCDLLAIKPDGYKSPLEEV
>Mature_310_residues
MMDYQKLLVVVDPTTEKQAALARAVELASESKAEITVFLSIFDFSYEMTSILSGQEREAMREGVINQRKAWIDDIIKPYC
KDGIKVTSEVIWHNRPFESIIRQAIDGNYDLIVKGTHEHDKLKSVIFTPTDWHLMRKAPIPVLLVKEHDWPVAGKIVCAI
NVSAEDDANETLNGKIITHASKLAKQFNAQVHLVNGYPGTPVNLAIELPDFDAHTYSETIRLQHEERICYLANAYGISPD
FCHVKEGLPEDVIPDLAAELDAELVILGTVGRTGLSAALIGNTAEHVIDSINCDLLAIKPDGYKSPLEEV

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1787594, Length=309, Percent_Identity=52.7508090614887, Blast_Score=347, Evalue=7e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 34441; Mature: 34441

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDYQKLLVVVDPTTEKQAALARAVELASESKAEITVFLSIFDFSYEMTSILSGQEREAM
CCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHCCHHHHHH
REGVINQRKAWIDDIIKPYCKDGIKVTSEVIWHNRPFESIIRQAIDGNYDLIVKGTHEHD
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCHH
KLKSVIFTPTDWHLMRKAPIPVLLVKEHDWPVAGKIVCAINVSAEDDANETLNGKIITHA
HHHEEEECCCCCHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCEEEHHH
SKLAKQFNAQVHLVNGYPGTPVNLAIELPDFDAHTYSETIRLQHEERICYLANAYGISPD
HHHHHHHCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHEEEECCCCEEEEEECCCCCCC
FCHVKEGLPEDVIPDLAAELDAELVILGTVGRTGLSAALIGNTAEHVIDSINCDLLAIKP
HHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCHHHHHHHCCCCEEEECC
DGYKSPLEEV
CCCCCCHHCC
>Mature Secondary Structure
MMDYQKLLVVVDPTTEKQAALARAVELASESKAEITVFLSIFDFSYEMTSILSGQEREAM
CCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHCCHHHHHH
REGVINQRKAWIDDIIKPYCKDGIKVTSEVIWHNRPFESIIRQAIDGNYDLIVKGTHEHD
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCHH
KLKSVIFTPTDWHLMRKAPIPVLLVKEHDWPVAGKIVCAINVSAEDDANETLNGKIITHA
HHHEEEECCCCCHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCEEEHHH
SKLAKQFNAQVHLVNGYPGTPVNLAIELPDFDAHTYSETIRLQHEERICYLANAYGISPD
HHHHHHHCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHEEEECCCCEEEEEECCCCCCC
FCHVKEGLPEDVIPDLAAELDAELVILGTVGRTGLSAALIGNTAEHVIDSINCDLLAIKP
HHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCHHHHHHHCCCCEEEECC
DGYKSPLEEV
CCCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]