Click here to switch to the map view.

The map label for this gene is csgD [H]

Identifier: 157961641

GI number: 157961641

Start: 2220539

End: 2221174

Strand: Direct

Name: csgD [H]

Synonym: Spea_1817

Alternate gene names: 157961641

Gene position: 2220539-2221174 (Clockwise)

Preceding gene: 157961640

Following gene: 157961642

Centisome position: 42.91

GC content: 42.45

Gene sequence:

>636_bases
ATGTTTAAAGTGATACATTGGGTCGTCGTTACCCGTTCGCATCTGTTTGCGGATCTTCTCAATACTCGATGGCCACAAGA
GTTTTTGGTCAAACTTCATCGGATCTCTCCTGAACACTTTAATGGTGATCTATTAGAGAGTCGCATTACGATTATTTTAA
TCGATCTTGCAACTGTCGATGTTCAAACCGCCTATCAGATCCAAAAACGGGTTGAAAAAGGTAGCAACATTGCACGAGTG
GTATTTGTGCACTTCCCTAAGCAAGTTGATGCCAAGTTTTTAGTGCAGTCATCTATTACTGCTGGTGTGTTTTATTCTGA
CGCTTCACTAGAAGCCATTGGAGAAGGCATGGCAGAGATAGTAAAAGGTAAAGTTGTTATTCCTCAGGCCATTATTGAAG
CTAACACCAATAAAGATCCTGCCTTAGATAATGTCGATACCCTCACTATCCGTGAGCGAGAAGTGCTACAGGTGCTGCGT
AATGGTAGTACCAATATCGATATCGCTAATAGGTTATTTGTCAGCGAAAGCACCATCAAAACCCATCTTTATAGAGCCTT
TAGAAAGATTGGAGTCTCTAGCCGAGGACAAGCAATTGCCTGGGCGCAGACTAACCTACATGAAGTGACTCAGTGA

Upstream 100 bases:

>100_bases
CGTTGTGTTTGTGTGAATATTTTGATGTTTCTTTCTCGATTAAATATATTACAATAACGGTCACACGGATGGTGATATAG
AACAAACACGGAGTGAGTTT

Downstream 100 bases:

>100_bases
AGCGCTTGTATCTAAGCTTACTACTCTTTTTGCAACCCGCAGCAGCAGAGGAGATTGTATTAGATAAGCAGTCTCCTCCT
GCAGCTAAAAATACCAGCGA

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFKVIHWVVVTRSHLFADLLNTRWPQEFLVKLHRISPEHFNGDLLESRITIILIDLATVDVQTAYQIQKRVEKGSNIARV
VFVHFPKQVDAKFLVQSSITAGVFYSDASLEAIGEGMAEIVKGKVVIPQAIIEANTNKDPALDNVDTLTIREREVLQVLR
NGSTNIDIANRLFVSESTIKTHLYRAFRKIGVSSRGQAIAWAQTNLHEVTQ

Sequences:

>Translated_211_residues
MFKVIHWVVVTRSHLFADLLNTRWPQEFLVKLHRISPEHFNGDLLESRITIILIDLATVDVQTAYQIQKRVEKGSNIARV
VFVHFPKQVDAKFLVQSSITAGVFYSDASLEAIGEGMAEIVKGKVVIPQAIIEANTNKDPALDNVDTLTIREREVLQVLR
NGSTNIDIANRLFVSESTIKTHLYRAFRKIGVSSRGQAIAWAQTNLHEVTQ
>Mature_211_residues
MFKVIHWVVVTRSHLFADLLNTRWPQEFLVKLHRISPEHFNGDLLESRITIILIDLATVDVQTAYQIQKRVEKGSNIARV
VFVHFPKQVDAKFLVQSSITAGVFYSDASLEAIGEGMAEIVKGKVVIPQAIIEANTNKDPALDNVDTLTIREREVLQVLR
NGSTNIDIANRLFVSESTIKTHLYRAFRKIGVSSRGQAIAWAQTNLHEVTQ

Specific function: The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA t

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787277, Length=218, Percent_Identity=30.7339449541284, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 23787; Mature: 23787

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKVIHWVVVTRSHLFADLLNTRWPQEFLVKLHRISPEHFNGDLLESRITIILIDLATVD
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHCCEEEEEEEEHHCC
VQTAYQIQKRVEKGSNIARVVFVHFPKQVDAKFLVQSSITAGVFYSDASLEAIGEGMAEI
HHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHH
VKGKVVIPQAIIEANTNKDPALDNVDTLTIREREVLQVLRNGSTNIDIANRLFVSESTIK
HCCCEEECHHHHCCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCEEEHHEEEECHHHHH
THLYRAFRKIGVSSRGQAIAWAQTNLHEVTQ
HHHHHHHHHHCCCCCCCEEEEECCCHHHHCC
>Mature Secondary Structure
MFKVIHWVVVTRSHLFADLLNTRWPQEFLVKLHRISPEHFNGDLLESRITIILIDLATVD
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHCCEEEEEEEEHHCC
VQTAYQIQKRVEKGSNIARVVFVHFPKQVDAKFLVQSSITAGVFYSDASLEAIGEGMAEI
HHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHH
VKGKVVIPQAIIEANTNKDPALDNVDTLTIREREVLQVLRNGSTNIDIANRLFVSESTIK
HCCCEEECHHHHCCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCCEEEHHEEEECHHHHH
THLYRAFRKIGVSSRGQAIAWAQTNLHEVTQ
HHHHHHHHHHCCCCCCCEEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8817489; 8905232; 9278503 [H]