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The map label for this gene is htpX [H]

Identifier: 157961629

GI number: 157961629

Start: 2204080

End: 2204943

Strand: Direct

Name: htpX [H]

Synonym: Spea_1805

Alternate gene names: 157961629

Gene position: 2204080-2204943 (Clockwise)

Preceding gene: 157961628

Following gene: 157961630

Centisome position: 42.59

GC content: 45.6

Gene sequence:

>864_bases
ATGAAGCGTATATTTTTACTGATTGCCACTAACATGGCGATCTTATTGGTGGCATCGATTGTGATGTCAATTTTAGGTGT
TAACACCTCAACCATGGGCGGCTTACTTGTGTTTGCTGCAATATTTGGTTTCGGTGGTGCATTTATCAGCTTGGCAATCT
CAAAGTGGATGGCTAAGAAGACCATGGGTTGTGAGGTTATTACTACGCCACGTGATAACACCGAGCGTTGGTTAGTTGAG
ACGGTTGCCCGTCAAGCTGAGCAAGCTGGGATTAAGATGCCAGAAGTCGCGATTTACCAATCGCCAGAACTGAACGCATT
TGCAACGGGTCCAAGCAAGGACAACTCGTTAGTCGCTGTGAGTAGCGGTTTACTTTATGGCATGAATCAAGATGAGATTG
AAGCGGTACTTGCTCACGAAGTTAGTCACGTTGCCAACGGTGATATGGTGACGCTGACGCTTATTCAAGGCGTGGTGAAC
ACCTTCGTTATTTTCGCAGCACGTGTTGTTGCGGGTATCATTGATAACTTTGTTTCAAGCAATGATGAAGAGGGCGAAGG
CCTAGGCATGTTCGCTTATATGGCAGTCGTGTTCGTACTAGATATGCTATTCGGTATCTTAGCCTCAATGATTGTTGCTT
ACTTCTCTCGTATTCGCGAATACAGAGCCGATGAAGGCGCTGCAAAACTTGCTGGTAAAGAGAAGATGATTGCTGCGCTG
GATAGATTACGTCAAGGCCCTGAAACAGGTGCGATGCCTGCATCTATGTCAGCATTGGGTATTAACGGTAAGAAATCTAT
GGCGGAATTGATGATGAGTCATCCACCATTAGAAAAGCGTATCGAAGCGTTAAGAGCTCACTAA

Upstream 100 bases:

>100_bases
GATAGATTATTTTCGTTCTCTCCCCTTGAATTCTTGTTTTTTGGACATATTATGTCTCCAAGAGTGTATATCAGGTACTT
TGTATCCTACAGGAGCTTAA

Downstream 100 bases:

>100_bases
ATTATCTTACTTGCAAGTAAAGCGGTTTGGGACTAAAAGTCTCAAACCGCTTTTTTATTGCTCAAAATCAAAGTGATAAA
TAGTGAAAACAAGCATGTTC

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKRIFLLIATNMAILLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDNTERWLVE
TVARQAEQAGIKMPEVAIYQSPELNAFATGPSKDNSLVAVSSGLLYGMNQDEIEAVLAHEVSHVANGDMVTLTLIQGVVN
TFVIFAARVVAGIIDNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASMIVAYFSRIREYRADEGAAKLAGKEKMIAAL
DRLRQGPETGAMPASMSALGINGKKSMAELMMSHPPLEKRIEALRAH

Sequences:

>Translated_287_residues
MKRIFLLIATNMAILLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDNTERWLVE
TVARQAEQAGIKMPEVAIYQSPELNAFATGPSKDNSLVAVSSGLLYGMNQDEIEAVLAHEVSHVANGDMVTLTLIQGVVN
TFVIFAARVVAGIIDNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASMIVAYFSRIREYRADEGAAKLAGKEKMIAAL
DRLRQGPETGAMPASMSALGINGKKSMAELMMSHPPLEKRIEALRAH
>Mature_287_residues
MKRIFLLIATNMAILLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDNTERWLVE
TVARQAEQAGIKMPEVAIYQSPELNAFATGPSKDNSLVAVSSGLLYGMNQDEIEAVLAHEVSHVANGDMVTLTLIQGVVN
TFVIFAARVVAGIIDNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASMIVAYFSRIREYRADEGAAKLAGKEKMIAAL
DRLRQGPETGAMPASMSALGINGKKSMAELMMSHPPLEKRIEALRAH

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=288, Percent_Identity=57.9861111111111, Blast_Score=331, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30859; Mature: 30859

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIFLLIATNMAILLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKK
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMGCEVITTPRDNTERWLVETVARQAEQAGIKMPEVAIYQSPELNAFATGPSKDNSLVAV
HCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCCCCEEEE
SSGLLYGMNQDEIEAVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIIDNFVSS
ECCEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDEEGEGLGMFAYMAVVFVLDMLFGILASMIVAYFSRIREYRADEGAAKLAGKEKMIAAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DRLRQGPETGAMPASMSALGINGKKSMAELMMSHPPLEKRIEALRAH
HHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKRIFLLIATNMAILLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKK
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMGCEVITTPRDNTERWLVETVARQAEQAGIKMPEVAIYQSPELNAFATGPSKDNSLVAV
HCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCCCCCCCEEEE
SSGLLYGMNQDEIEAVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIIDNFVSS
ECCEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDEEGEGLGMFAYMAVVFVLDMLFGILASMIVAYFSRIREYRADEGAAKLAGKEKMIAAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DRLRQGPETGAMPASMSALGINGKKSMAELMMSHPPLEKRIEALRAH
HHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA