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The map label for this gene is sucD [H]

Identifier: 157961615

GI number: 157961615

Start: 2187923

End: 2188795

Strand: Direct

Name: sucD [H]

Synonym: Spea_1791

Alternate gene names: 157961615

Gene position: 2187923-2188795 (Clockwise)

Preceding gene: 157961614

Following gene: 157961616

Centisome position: 42.28

GC content: 45.82

Gene sequence:

>873_bases
ATGTCTGTATTAATTAACAAAGATACCAAAGTTATCTGTCAAGGTTTCACTGGCGGTCAAGGTACGTTCCACTCTGAGCA
AGCTATCGCTTATGGCACAAAGATGGTCGGTGGTGTGTCTCCAGGAAAAGGCGGTCAAATCCACTTAGGTCTTCCAGTAT
TCAATACTGTTAAAGACGCTGTGGAAGTGACAGGTGCAACGGCTTCAGTTATCTACGTTCCAGCACCTTTCTGTAAAGAT
GCAATCCTAGAAGCAATCGACGGTGGCATCGAGCTAATCGTTTGTATTACTGAAGGGATCCCAACGTTAGATATGCTTCA
AGTTAAAGTTAAGCTTGAAGAAACTGGCGTTCGCATGATTGGTCCAAACTGCCCAGGTGTTATTACTCCTGGTGAGTGTA
AGATTGGTATCATGCCTGGTCACATCCACAAGCCAGGTAAAGTCGGCATTGTTTCTCGCTCTGGTACATTAACCTACGAA
GCGGTTAAGCAAACTACTGATGAAGGTTTTGGCCAATCAACTTGTGTCGGTATTGGTGGAGACCCAATTCCAGGTACTAA
CTTCATCGACGTATTGGAAATGTTCCAAAACGATCCACTTACTGAAGCAATCGTGATGATTGGTGAAATTGGTGGTACTG
CTGAAGAAGAAGCGGCTGAATACATCAAGGCTAACGTCACTAAGCCTGTAGTTTCATACATTGCCGGTGTGACTGCACCA
GAAGGCAAGCGTATGGGTCATGCTGGCGCAATTATCGCTGGCGGTAAGGGTACGGCAGAAGACAAGTTTGCAGCTCTTGA
AGCTGCAGGCGTTACGACAGTACGTTCACTTGCTGACATCGGTAAGGCATTACGCACTAAGACTGGTTGGTAA

Upstream 100 bases:

>100_bases
TAGGTCGTGAAGTTCTAGCTAACTCTGACCTTGATATCATCGCTGCTACAAGTCTAACTGACGCGGCTGAGCAAGTAGTT
AAAGCTGCGGAGGGCAAATA

Downstream 100 bases:

>100_bases
ACACTAATTAGTTATTAAAAGGCGCCTAGAGCGCCTTTTTTATTGCCTAAAAAGAAGGTGTTCCTACGTATTTAATCATA
CTGGTATAAGTCTATTTTTG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSVLINKDTKVICQGFTGGQGTFHSEQAIAYGTKMVGGVSPGKGGQIHLGLPVFNTVKDAVEVTGATASVIYVPAPFCKD
AILEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMIGPNCPGVITPGECKIGIMPGHIHKPGKVGIVSRSGTLTYE
AVKQTTDEGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPLTEAIVMIGEIGGTAEEEAAEYIKANVTKPVVSYIAGVTAP
EGKRMGHAGAIIAGGKGTAEDKFAALEAAGVTTVRSLADIGKALRTKTGW

Sequences:

>Translated_290_residues
MSVLINKDTKVICQGFTGGQGTFHSEQAIAYGTKMVGGVSPGKGGQIHLGLPVFNTVKDAVEVTGATASVIYVPAPFCKD
AILEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMIGPNCPGVITPGECKIGIMPGHIHKPGKVGIVSRSGTLTYE
AVKQTTDEGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPLTEAIVMIGEIGGTAEEEAAEYIKANVTKPVVSYIAGVTAP
EGKRMGHAGAIIAGGKGTAEDKFAALEAAGVTTVRSLADIGKALRTKTGW
>Mature_289_residues
SVLINKDTKVICQGFTGGQGTFHSEQAIAYGTKMVGGVSPGKGGQIHLGLPVFNTVKDAVEVTGATASVIYVPAPFCKDA
ILEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMIGPNCPGVITPGECKIGIMPGHIHKPGKVGIVSRSGTLTYEA
VKQTTDEGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPLTEAIVMIGEIGGTAEEEAAEYIKANVTKPVVSYIAGVTAPE
GKRMGHAGAIIAGGKGTAEDKFAALEAAGVTTVRSLADIGKALRTKTGW

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=284, Percent_Identity=68.6619718309859, Blast_Score=335, Evalue=4e-92,
Organism=Homo sapiens, GI38569423, Length=259, Percent_Identity=33.5907335907336, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI38569421, Length=259, Percent_Identity=33.5907335907336, Blast_Score=108, Evalue=4e-24,
Organism=Escherichia coli, GI1786949, Length=286, Percent_Identity=87.0629370629371, Blast_Score=504, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17550194, Length=290, Percent_Identity=63.1034482758621, Blast_Score=339, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17553126, Length=289, Percent_Identity=62.9757785467128, Blast_Score=337, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI17557344, Length=255, Percent_Identity=31.3725490196078, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17551266, Length=255, Percent_Identity=30.9803921568627, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=53.7671232876712, Blast_Score=290, Evalue=2e-79,
Organism=Drosophila melanogaster, GI28574296, Length=288, Percent_Identity=62.5, Blast_Score=327, Evalue=5e-90,
Organism=Drosophila melanogaster, GI21356559, Length=288, Percent_Identity=58.6805555555556, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI281363477, Length=255, Percent_Identity=29.0196078431373, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363475, Length=255, Percent_Identity=29.0196078431373, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363473, Length=255, Percent_Identity=29.0196078431373, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29926; Mature: 29795

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLINKDTKVICQGFTGGQGTFHSEQAIAYGTKMVGGVSPGKGGQIHLGLPVFNTVKDA
CEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHH
VEVTGATASVIYVPAPFCKDAILEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMI
HHHCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEEEEECCCEEEE
GPNCPGVITPGECKIGIMPGHIHKPGKVGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGG
CCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIPGTNFIDVLEMFQNDPLTEAIVMIGEIGGTAEEEAAEYIKANVTKPVVSYIAGVTAP
CCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCC
EGKRMGHAGAIIAGGKGTAEDKFAALEAAGVTTVRSLADIGKALRTKTGW
CCCCCCCCCEEEECCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVLINKDTKVICQGFTGGQGTFHSEQAIAYGTKMVGGVSPGKGGQIHLGLPVFNTVKDA
EEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHH
VEVTGATASVIYVPAPFCKDAILEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMI
HHHCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEEEEECCCEEEE
GPNCPGVITPGECKIGIMPGHIHKPGKVGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGG
CCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIPGTNFIDVLEMFQNDPLTEAIVMIGEIGGTAEEEAAEYIKANVTKPVVSYIAGVTAP
CCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCC
EGKRMGHAGAIIAGGKGTAEDKFAALEAAGVTTVRSLADIGKALRTKTGW
CCCCCCCCCEEEECCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]