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The map label for this gene is sucC [H]

Identifier: 157961614

GI number: 157961614

Start: 2186757

End: 2187923

Strand: Direct

Name: sucC [H]

Synonym: Spea_1790

Alternate gene names: 157961614

Gene position: 2186757-2187923 (Clockwise)

Preceding gene: 157961613

Following gene: 157961615

Centisome position: 42.26

GC content: 45.84

Gene sequence:

>1167_bases
ATGAATTTGCATGAATATCAGGCAAAAGCCCTATTTGCCGAATATGGTTTACCAGTGTCAGAAGGTTTTGCATGTGATAC
TGCCCAAGAAGCAGTTGAAGCAGCAGGCCATATTGGCGGTGATATGTGGGTTGTTAAGTGTCAAGTACACGCTGGCGGCC
GTGGTAAAGCGGGTGGCGTTAAAGTCACTGGCGACAAAGAAGAGATCAGAGCATTTGCTGAGCATTGGTTAGGTAAGAAC
CTTGTTACTTATCAGACTGATGAGAAAGGTCAGCCAGTTGCTAAAATTTTAGTAGAAAGCTGTACTGATATCGCAAATGA
ATTGTACCTAGGTGCAGTAGTCGATCGCTCAACACGTCGCGTTGTGTTTATGGCATCGACTGAAGGCGGTGTGGAAATTG
AAACTGTGGCCGAAGAAACGCCAGAGTTGATCCACAAAGCTATCATCGATCCGCTTACAGGCCCTCAGCCATACCAAGCT
CGCGATCTTGGCTTCAAGTTAGGTCTTAACCCAACACAAATGAAGCAATTCACTAAAGTCTTTATGGGCTTAGCGAAAAT
GTTTGAAGATCATGATTTTGCTCTACTTGAAATCAACCCACTTGTTATCACTGACGAAGGCAACATTCACTGTCTTGATG
GCAAGATTGGTATCGATGGCAACGCTTTATTCCGTCAGCCTAAGATCCGTGATATGCACGATCCATCACAAGATGATGCT
CGTGAAGCGCACGCGGCTAAGTTCGAGCTTAACTATGTAGCACTAGACGGAAACGTTGGCTGCATGGTGAATGGTGCAGG
CCTAGCGATGGGCACTATGGATATCGTTAACCTACACGGTGGCAAGCCAGCTAACTTCTTAGACGTTGGTGGTGGAGCAA
CTAAAGAGCGAGTAGCTGAAGCATTCAAGATCATCTTGTCTGATTCAAACGTTAAAGCGGTTCTTGTGAACATCTTTGGT
GGCATCGTTCGTTGTGACATGATTGCTGAAGGTATCATCGGTGCAGTTAAAGAAGTGGGTGTTGAAGTACCAGTTGTTGT
TCGTCTTGAAGGTACTAACGCCGACCTAGGTCGTGAAGTTCTAGCTAACTCTGACCTTGATATCATCGCTGCTACAAGTC
TAACTGACGCGGCTGAGCAAGTAGTTAAAGCTGCGGAGGGCAAATAA

Upstream 100 bases:

>100_bases
TCGTCTGCTTCTTGACCTATAAGTCAAGACAGACAATACCCTAGCTGCGGGCCCGTTTGGGCCTGCTGAAATACATAAGA
AGTATAATGGATAGATCATC

Downstream 100 bases:

>100_bases
TGTCTGTATTAATTAACAAAGATACCAAAGTTATCTGTCAAGGTTTCACTGGCGGTCAAGGTACGTTCCACTCTGAGCAA
GCTATCGCTTATGGCACAAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRRVVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKVFMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDA
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNADLGREVLANSDLDIIAATSLTDAAEQVVKAAEGK

Sequences:

>Translated_388_residues
MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRRVVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKVFMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDA
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNADLGREVLANSDLDIIAATSLTDAAEQVVKAAEGK
>Mature_388_residues
MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRRVVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKVFMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDA
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNADLGREVLANSDLDIIAATSLTDAAEQVVKAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=46.0559796437659, Blast_Score=339, Evalue=3e-93,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=45.2196382428941, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=45.7300275482094, Blast_Score=299, Evalue=2e-81,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=76.2886597938144, Blast_Score=585, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=43.7017994858612, Blast_Score=315, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=41.5, Blast_Score=300, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=42.1717171717172, Blast_Score=322, Evalue=5e-89,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=43.3249370277078, Blast_Score=304, Evalue=6e-83,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=42.2391857506361, Blast_Score=287, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=42.2391857506361, Blast_Score=287, Evalue=7e-78,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=42.3857868020305, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=42.3857868020305, Blast_Score=285, Evalue=3e-77,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41484; Mature: 41484

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCE
KVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRR
EEECCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEHEEECCCCCE
VVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKV
EEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEECCCHHHHHHHHHH
FMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDA
HHHHHHHHCCCCEEEEEEEEEEEECCCCEEEECCEEECCCCCEECCCCCCCCCCCCCHHH
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHEEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNADLGREV
HHHHEECCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
LANSDLDIIAATSLTDAAEQVVKAAEGK
HCCCCCCEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLHEYQAKALFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCE
KVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRR
EEECCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEHEEECCCCCE
VVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKV
EEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEECCCHHHHHHHHHH
FMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQPKIRDMHDPSQDDA
HHHHHHHHCCCCEEEEEEEEEEEECCCCEEEECCEEECCCCCEECCCCCCCCCCCCCHHH
REAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHEEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVEVPVVVRLEGTNADLGREV
HHHHEECCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
LANSDLDIIAATSLTDAAEQVVKAAEGK
HCCCCCCEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA